A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
ENSG00000168310.6 | interferon regulatory factor 2 | |
ENSG00000170581.9 | signal transducer and activator of transcription 2 | |
ENSG00000140968.6 | interferon regulatory factor 8 | |
ENSG00000125347.9 | interferon regulatory factor 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
STAT2 | hg19_v2_chr12_-_56753858_56753930 | 1.00 | 4.5e-03 | Click! |
IRF1 | hg19_v2_chr5_-_131826457_131826514 | 0.99 | 8.7e-03 | Click! |
IRF2 | hg19_v2_chr4_-_185395672_185395734 | 0.96 | 3.6e-02 | Click! |
IRF8 | hg19_v2_chr16_+_85942594_85942635 | -0.59 | 4.1e-01 | Click! |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr10_+_91152303 Show fit | 88.81 |
ENST00000371804.3
|
interferon-induced protein with tetratricopeptide repeats 1 |
|
chr10_+_91087651 Show fit | 79.72 |
ENST00000371818.4
|
interferon-induced protein with tetratricopeptide repeats 3 |
|
chr1_+_948803 Show fit | 77.51 |
ENST00000379389.4
|
ISG15 ubiquitin-like modifier |
|
chr10_+_91092241 Show fit | 72.82 |
ENST00000371811.4
|
interferon-induced protein with tetratricopeptide repeats 3 |
|
chr12_+_113416191 Show fit | 67.42 |
ENST00000342315.4
ENST00000392583.2 |
2'-5'-oligoadenylate synthetase 2, 69/71kDa |
|
chr2_-_7005785 Show fit | 59.02 |
ENST00000256722.5
ENST00000404168.1 ENST00000458098.1 |
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial |
|
chr1_+_79086088 Show fit | 56.54 |
ENST00000370751.5
ENST00000342282.3 |
interferon-induced protein 44-like |
|
chr21_+_42792442 Show fit | 54.02 |
ENST00000398600.2
|
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) |
|
chr22_+_18632666 Show fit | 53.31 |
ENST00000215794.7
|
ubiquitin specific peptidase 18 |
|
chr11_-_64764435 Show fit | 51.17 |
ENST00000534177.1
ENST00000301887.4 |
basic leucine zipper transcription factor, ATF-like 2 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.8 | 379.8 | GO:0071357 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
14.5 | 202.6 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
2.9 | 192.4 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
13.8 | 166.2 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
6.8 | 142.0 | GO:0003373 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
11.8 | 130.0 | GO:0018377 | protein myristoylation(GO:0018377) |
22.6 | 90.5 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
22.3 | 89.3 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
22.2 | 88.8 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
8.0 | 88.4 | GO:0045341 | MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 269.6 | GO:0005739 | mitochondrion(GO:0005739) |
0.0 | 157.8 | GO:0005634 | nucleus(GO:0005634) |
0.1 | 157.2 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.1 | 148.9 | GO:0005730 | nucleolus(GO:0005730) |
0.3 | 106.8 | GO:0031965 | nuclear membrane(GO:0031965) |
1.0 | 80.4 | GO:0015030 | Cajal body(GO:0015030) |
0.1 | 75.2 | GO:0042175 | nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175) |
0.4 | 74.1 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.6 | 70.5 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
0.6 | 68.5 | GO:0005811 | lipid particle(GO:0005811) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
23.6 | 282.8 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
0.3 | 184.2 | GO:0005525 | GTP binding(GO:0005525) |
2.9 | 137.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
1.0 | 126.6 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.7 | 96.4 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
0.5 | 83.7 | GO:0001047 | core promoter binding(GO:0001047) |
6.0 | 77.5 | GO:0031386 | protein tag(GO:0031386) |
0.0 | 73.8 | GO:0042802 | identical protein binding(GO:0042802) |
4.1 | 73.1 | GO:0008035 | high-density lipoprotein particle binding(GO:0008035) |
1.4 | 69.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.3 | 88.5 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.4 | 70.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.4 | 40.8 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
0.5 | 38.3 | PID AURORA A PATHWAY | Aurora A signaling |
0.6 | 33.6 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
0.1 | 28.9 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.8 | 28.7 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
0.4 | 23.5 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
0.5 | 23.2 | PID MYC PATHWAY | C-MYC pathway |
0.2 | 19.5 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
13.5 | 1291.7 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
2.2 | 116.8 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
6.5 | 104.1 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
1.3 | 78.8 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.2 | 63.9 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.8 | 57.9 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
1.3 | 37.8 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.9 | 34.2 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
1.3 | 27.1 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.5 | 17.9 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |