ISMARA results: IKZF1

Project

A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for IKZF1

Z-value: 1.72

Motif logo

Transcription factors associated with IKZF1

Gene Symbol	Gene ID	Gene Info
IKZF1 Ensembl NCBI GeneCards UniProt	ENSG00000185811.12	IKAROS family zinc finger 1

Activity profile of IKZF1 motif

Sorted Z-values of IKZF1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_+_130184888 Show fit	0.81	ENST00000602376.1 ENST00000532116.3 ENST00000602310.1	RP11-121M22.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-121M22.1
chr7_-_139727118 Show fit	0.78	ENST00000484111.1	PARP12 Ensembl NCBI GeneCards UniProt Show fit	poly (ADP-ribose) polymerase family, member 12
chr12_-_25150373 Show fit	0.74	ENST00000549828.1	C12orf77 Ensembl NCBI GeneCards UniProt Show fit	chromosome 12 open reading frame 77
chr19_-_47128294 Show fit	0.73	ENST00000596260.1 ENST00000597185.1 ENST00000598865.1 ENST00000594275.1 ENST00000291294.2	PTGIR Ensembl NCBI GeneCards UniProt Show fit	prostaglandin I2 (prostacyclin) receptor (IP)
chr15_-_74284558 Show fit	0.71	ENST00000359750.4 ENST00000541638.1 ENST00000562453.1	STOML1 Ensembl NCBI GeneCards UniProt Show fit	stomatin (EPB72)-like 1
chr19_-_17010360 Show fit	0.68	ENST00000599287.2	CPAMD8 Ensembl NCBI GeneCards UniProt Show fit	C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr12_-_58212487 Show fit	0.66	ENST00000549994.1	AVIL Ensembl NCBI GeneCards UniProt Show fit	advillin
chr12_+_14369524 Show fit	0.63	ENST00000538329.1	RP11-134N1.2 Ensembl NCBI GeneCards UniProt Show fit	RP11-134N1.2
chr19_+_29493486 Show fit	0.62	ENST00000589821.1	CTD-2081K17.2 Ensembl NCBI GeneCards UniProt Show fit	CTD-2081K17.2
chr19_+_39759154 Show fit	0.62	ENST00000331982.5	IFNL2 Ensembl NCBI GeneCards UniProt Show fit	interferon, lambda 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.7	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	5.8	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	3.9	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	2.9	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.1	1.7	GO:0003373	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0	1.7	GO:0070126	mitochondrial translational termination(GO:0070126)
0.2	1.5	GO:0036018	cellular response to erythropoietin(GO:0036018)
0.1	1.5	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0	1.4	GO:0070268	cornification(GO:0070268)
0.1	1.2	GO:0030150	protein import into mitochondrial matrix(GO:0030150)

Showing 1 to 10 of 1,077 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.9	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	3.2	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	2.9	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	2.1	GO:0031430	M band(GO:0031430)
0.0	2.0	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2	1.5	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	1.4	GO:0045095	keratin filament(GO:0045095)
0.0	1.3	GO:0044295	axonal growth cone(GO:0044295)
0.1	1.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	1.2	GO:0000118	histone deacetylase complex(GO:0000118)

Showing 1 to 10 of 327 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	9.0	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	4.9	GO:0005125	cytokine activity(GO:0005125)
0.0	2.6	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2	2.5	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	2.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	2.3	GO:0051082	unfolded protein binding(GO:0051082)
0.1	1.8	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	1.8	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	1.7	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	1.3	GO:0042826	histone deacetylase binding(GO:0042826)

Showing 1 to 10 of 605 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	7.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	2.7	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	2.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	1.9	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.6	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.4	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	1.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling

Showing 1 to 10 of 56 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	11.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	7.5	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	4.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	3.8	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	2.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	1.7	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	1.5	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	1.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	1.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA

Showing 1 to 10 of 114 entries

Results for IKZF1

Z-value: 1.72

Motif logo

Transcription factors associated with IKZF1

Activity profile of IKZF1 motif

Sorted Z-values of IKZF1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: