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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for ID4_TCF4_SNAI2
Z-value: 1.38
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Transcription factors associated with ID4_TCF4_SNAI2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ID4 | hg19_v2_chr6_+_19837592_19837621 | -1.00 | 3.0e-03 | Click! |
| TCF4 | hg19_v2_chr18_-_52989525_52989623 | -0.88 | 1.2e-01 | Click! |
| SNAI2 | hg19_v2_chr8_-_49834299_49834446 | -0.44 | 5.6e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ID4_TCF4_SNAI2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 0.2 | 1.5 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.0 | 1.3 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 1.2 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.2 | 1.0 | GO:0015864 | uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864) |
| 0.1 | 1.0 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.1 | 1.0 | GO:0071316 | cellular response to nicotine(GO:0071316) |
| 0.0 | 1.0 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.0 | 1.0 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 0.9 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.1 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 2.0 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 1.9 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 1.6 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 1.4 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.2 | 1.2 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.1 | 1.2 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.0 | 1.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 1.1 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 1.1 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 1.9 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 1.3 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.1 | 1.2 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.1 | 1.0 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.0 | 1.0 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.8 | GO:0004473 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.1 | 0.8 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.1 | 0.8 | GO:0051525 | NFAT protein binding(GO:0051525) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.4 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 2.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.9 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 1.7 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 1.3 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 1.3 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 1.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.8 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.0 | 0.8 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.3 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 1.1 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 1.1 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 1.0 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 1.0 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.9 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.9 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.9 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.8 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |