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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HSF2

Z-value: 1.66

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Transcription factors associated with HSF2

Gene Symbol Gene ID Gene Info
HSF2
ENSG00000025156.8 heat shock transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF2hg19_v2_chr6_+_122720681_122720713-0.964.4e-02Click!

Activity profile of HSF2 motif

Sorted Z-values of HSF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_33025209 1.60 ENST00000330899.4
ENST00000544625.1
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr14_-_67859422 1.40 ENST00000556532.1
PLEK2
pleckstrin 2
chrX_+_135279179 1.31 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr12_-_10007448 1.27 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chrX_+_135230712 0.94 ENST00000535737.1
FHL1
four and a half LIM domains 1
chrX_+_135278908 0.92 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr1_-_228613026 0.91 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr15_-_81616446 0.90 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr1_+_41448820 0.89 ENST00000372616.1
CTPS1
CTP synthase 1
chr1_-_6453399 0.85 ENST00000608083.1
ACOT7
acyl-CoA thioesterase 7
chr10_+_135340859 0.79 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr4_+_14113592 0.79 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085
long intergenic non-protein coding RNA 1085
chr2_+_219824357 0.77 ENST00000302625.4
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr1_-_6453426 0.72 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chr6_+_151646800 0.70 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr3_-_48632593 0.69 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr10_-_90611566 0.67 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr14_-_77889860 0.67 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chr17_+_41052808 0.65 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
G6PC
glucose-6-phosphatase, catalytic subunit
chrX_-_152989499 0.64 ENST00000423827.1
BCAP31
B-cell receptor-associated protein 31
chr2_+_202937972 0.58 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr7_+_75931861 0.56 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chr11_-_133826852 0.55 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr6_-_31782813 0.55 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr8_-_81083618 0.55 ENST00000520795.1
TPD52
tumor protein D52
chr14_-_25479811 0.54 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr14_-_52535712 0.54 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr8_+_145065521 0.54 ENST00000534791.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr12_+_11802753 0.53 ENST00000396373.4
ETV6
ets variant 6
chr3_-_64673668 0.53 ENST00000498707.1
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr18_+_3451646 0.52 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr3_+_177534653 0.52 ENST00000436078.1
RP11-91K9.1
RP11-91K9.1
chr7_-_33080506 0.51 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr17_-_76573465 0.51 ENST00000585328.1
ENST00000389840.5
DNAH17
dynein, axonemal, heavy chain 17
chr19_+_19516561 0.51 ENST00000457895.2
GATAD2A
GATA zinc finger domain containing 2A
chr3_-_171489085 0.50 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr2_+_198365122 0.50 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr12_+_52404270 0.49 ENST00000552049.1
ENST00000546756.1
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr3_+_39509070 0.49 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr18_-_19284724 0.48 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr3_+_39509163 0.47 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chrX_-_152989531 0.44 ENST00000458587.2
ENST00000416815.1
BCAP31
B-cell receptor-associated protein 31
chr17_-_79817091 0.44 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr19_+_54606145 0.44 ENST00000485876.1
ENST00000391762.1
ENST00000471292.1
ENST00000391763.3
ENST00000391764.3
ENST00000303553.5
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr18_+_3449695 0.43 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr5_+_79331164 0.42 ENST00000350881.2
THBS4
thrombospondin 4
chr22_+_24577183 0.41 ENST00000358321.3
SUSD2
sushi domain containing 2
chrX_-_30993201 0.41 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr16_+_68119764 0.40 ENST00000570212.1
ENST00000562926.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr19_+_17416609 0.39 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr18_+_3451584 0.39 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr6_+_31783291 0.39 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
HSPA1A
heat shock 70kDa protein 1A
chr19_+_1438351 0.39 ENST00000233609.4
RPS15
ribosomal protein S15
chr17_+_35294075 0.39 ENST00000254457.5
LHX1
LIM homeobox 1
chr10_-_4285923 0.38 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr14_+_89060739 0.38 ENST00000318308.6
ZC3H14
zinc finger CCCH-type containing 14
chr16_+_55600580 0.38 ENST00000457326.2
CAPNS2
calpain, small subunit 2
chr16_+_4606347 0.36 ENST00000444310.4
C16orf96
chromosome 16 open reading frame 96
chr5_-_146833485 0.36 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr11_+_65769550 0.36 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
BANF1
barrier to autointegration factor 1
chr5_-_148442584 0.35 ENST00000394358.2
ENST00000512049.1
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr17_+_73663402 0.35 ENST00000355423.3
SAP30BP
SAP30 binding protein
chr8_+_145065705 0.35 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr17_-_7297833 0.34 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr13_+_24144796 0.34 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr12_+_50794891 0.34 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chr6_+_32121908 0.34 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr6_+_106534192 0.33 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr14_+_103800513 0.33 ENST00000560338.1
ENST00000560763.1
ENST00000558316.1
ENST00000558265.1
EIF5
eukaryotic translation initiation factor 5
chr5_-_146833222 0.32 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr18_+_3449821 0.32 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr21_+_45148735 0.32 ENST00000327574.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr19_+_1438383 0.32 ENST00000586686.2
ENST00000591032.1
ENST00000586656.1
ENST00000589656.2
ENST00000593052.1
ENST00000586096.2
ENST00000591804.2
RPS15
ribosomal protein S15
chr3_-_129407535 0.31 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr18_-_52989525 0.31 ENST00000457482.3
TCF4
transcription factor 4
chr20_+_44746939 0.30 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr13_+_46276441 0.29 ENST00000310521.1
ENST00000533564.1
SPERT
spermatid associated
chr2_+_162272605 0.29 ENST00000389554.3
TBR1
T-box, brain, 1
chr12_+_119616447 0.28 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr15_+_54305101 0.28 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C
unc-13 homolog C (C. elegans)
chr12_-_123011476 0.27 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2
arginine/serine-rich coiled-coil 2
chr6_+_31795506 0.26 ENST00000375650.3
HSPA1B
heat shock 70kDa protein 1B
chrX_-_110655306 0.26 ENST00000371993.2
DCX
doublecortin
chr8_+_134125727 0.26 ENST00000521107.1
TG
thyroglobulin
chr11_-_414948 0.25 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr12_+_69979113 0.25 ENST00000299300.6
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chrX_-_153775426 0.25 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr18_-_22804637 0.25 ENST00000577775.1
ZNF521
zinc finger protein 521
chr2_+_28615669 0.25 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr12_+_107078474 0.25 ENST00000552866.1
ENST00000229387.5
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr3_-_64673656 0.25 ENST00000459780.1
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr9_-_91793675 0.25 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chrX_-_128782722 0.25 ENST00000427399.1
APLN
apelin
chr3_-_185655795 0.25 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
TRA2B
transformer 2 beta homolog (Drosophila)
chr6_+_32121789 0.24 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chrY_-_20935572 0.24 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2
heat shock transcription factor, Y linked 2
chr6_+_32121218 0.24 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr4_-_186877502 0.24 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186877806 0.24 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr11_+_12696102 0.23 ENST00000527636.1
ENST00000527376.1
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_+_158733088 0.23 ENST00000605860.1
UPP2
uridine phosphorylase 2
chr12_+_69979210 0.23 ENST00000544368.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr15_-_93965805 0.23 ENST00000556708.1
RP11-164C12.2
RP11-164C12.2
chr2_-_122247879 0.22 ENST00000545861.1
CLASP1
cytoplasmic linker associated protein 1
chr1_+_27248203 0.22 ENST00000321265.5
NUDC
nudC nuclear distribution protein
chr2_+_143886877 0.22 ENST00000295095.6
ARHGAP15
Rho GTPase activating protein 15
chr7_+_120629653 0.22 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr11_-_65769594 0.22 ENST00000532707.1
ENST00000533544.1
ENST00000526451.1
ENST00000312234.2
ENST00000530462.1
ENST00000525767.1
ENST00000529964.1
ENST00000527249.1
EIF1AD
eukaryotic translation initiation factor 1A domain containing
chrY_+_20708557 0.22 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1
heat shock transcription factor, Y-linked 1
chr9_-_34589734 0.21 ENST00000378980.3
CNTFR
ciliary neurotrophic factor receptor
chr15_-_43785274 0.21 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chr19_-_14629224 0.21 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr3_+_10312604 0.21 ENST00000426850.1
TATDN2
TatD DNase domain containing 2
chr15_-_70388599 0.21 ENST00000560996.1
ENST00000558201.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr9_-_34589700 0.21 ENST00000351266.4
CNTFR
ciliary neurotrophic factor receptor
chr15_-_43785303 0.20 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1
tumor protein p53 binding protein 1
chr14_-_23624511 0.20 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chrX_-_72347916 0.19 ENST00000373518.1
NAP1L6
nucleosome assembly protein 1-like 6
chr12_+_69979446 0.19 ENST00000543146.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr3_+_96533621 0.19 ENST00000542517.1
ENST00000506569.1
EPHA6
EPH receptor A6
chr14_+_101293687 0.19 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr18_+_32173276 0.19 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr18_+_59000815 0.18 ENST00000262717.4
CDH20
cadherin 20, type 2
chr17_-_71410794 0.18 ENST00000424778.1
SDK2
sidekick cell adhesion molecule 2
chr4_+_123161120 0.18 ENST00000446180.1
KIAA1109
KIAA1109
chrX_-_19983260 0.18 ENST00000340625.3
CXorf23
chromosome X open reading frame 23
chr4_-_159644507 0.18 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chr11_+_65769946 0.18 ENST00000533166.1
BANF1
barrier to autointegration factor 1
chr6_+_42584847 0.18 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr5_+_133859996 0.17 ENST00000512386.1
PHF15
jade family PHD finger 2
chr12_-_45270077 0.17 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr15_-_58357866 0.17 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chrX_+_101478829 0.17 ENST00000372763.1
ENST00000372758.1
NXF2
nuclear RNA export factor 2
chr6_+_153019069 0.16 ENST00000532295.1
MYCT1
myc target 1
chr3_+_177545563 0.16 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr10_-_104913367 0.16 ENST00000423468.2
NT5C2
5'-nucleotidase, cytosolic II
chr7_-_80548493 0.16 ENST00000536800.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr17_-_60883993 0.16 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr9_-_4666421 0.16 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr7_-_78400598 0.15 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_-_112770674 0.15 ENST00000390666.3
TSSK1B
testis-specific serine kinase 1B
chr19_-_344786 0.15 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr9_-_4666337 0.15 ENST00000381890.5
SPATA6L
spermatogenesis associated 6-like
chr2_-_97405775 0.14 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chr1_+_151171012 0.13 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr2_-_178128149 0.13 ENST00000423513.1
NFE2L2
nuclear factor, erythroid 2-like 2
chrX_-_110655391 0.13 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chr20_+_31755934 0.13 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr15_+_78556428 0.13 ENST00000394855.3
ENST00000489435.2
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr19_-_55691472 0.13 ENST00000537500.1
SYT5
synaptotagmin V
chr2_-_219151487 0.13 ENST00000444881.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr12_+_2904102 0.12 ENST00000001008.4
FKBP4
FK506 binding protein 4, 59kDa
chr20_+_57427765 0.12 ENST00000371100.4
GNAS
GNAS complex locus
chr4_-_22517620 0.12 ENST00000502482.1
ENST00000334304.5
GPR125
G protein-coupled receptor 125
chr1_-_197744763 0.12 ENST00000422998.1
DENND1B
DENN/MADD domain containing 1B
chr1_-_184006611 0.11 ENST00000546159.1
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr3_-_49131473 0.11 ENST00000430979.1
ENST00000357496.2
ENST00000437939.1
QRICH1
glutamine-rich 1
chr13_-_20805109 0.11 ENST00000241124.6
GJB6
gap junction protein, beta 6, 30kDa
chr3_-_49131013 0.11 ENST00000424300.1
QRICH1
glutamine-rich 1
chrX_-_101718085 0.11 ENST00000372750.1
ENST00000372752.1
NXF2B
nuclear RNA export factor 2B
chr1_-_216596738 0.11 ENST00000307340.3
ENST00000366943.2
ENST00000366942.3
USH2A
Usher syndrome 2A (autosomal recessive, mild)
chr15_-_70388943 0.10 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr7_-_36764004 0.10 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr11_+_71791693 0.10 ENST00000289488.2
ENST00000447974.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr20_+_61867235 0.09 ENST00000342412.6
ENST00000217169.3
BIRC7
baculoviral IAP repeat containing 7
chr12_-_45269430 0.09 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr6_-_155635583 0.09 ENST00000367166.4
TFB1M
transcription factor B1, mitochondrial
chr8_+_38261880 0.09 ENST00000527175.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr7_-_103086598 0.09 ENST00000339444.6
ENST00000356767.4
ENST00000393735.2
ENST00000306312.3
ENST00000432958.2
SLC26A5
solute carrier family 26 (anion exchanger), member 5
chr13_+_42712178 0.09 ENST00000536612.1
DGKH
diacylglycerol kinase, eta
chr3_+_186692745 0.09 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr19_-_2085323 0.09 ENST00000591638.1
MOB3A
MOB kinase activator 3A
chr5_-_148442687 0.08 ENST00000515425.1
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chrX_+_51075658 0.08 ENST00000356450.2
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr4_-_48136217 0.08 ENST00000264316.4
TXK
TXK tyrosine kinase
chr12_+_54891495 0.08 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr13_+_49684445 0.08 ENST00000398316.3
FNDC3A
fibronectin type III domain containing 3A
chr7_+_18330035 0.07 ENST00000413509.2
HDAC9
histone deacetylase 9
chrX_+_153775821 0.07 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr19_+_6135646 0.07 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr15_+_78556809 0.07 ENST00000343789.3
ENST00000394852.3
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr20_+_44746885 0.07 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr7_-_26240357 0.07 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr5_-_35089722 0.06 ENST00000511486.1
ENST00000310101.5
ENST00000231423.3
ENST00000513753.1
ENST00000348262.3
ENST00000397391.3
ENST00000542609.1
PRLR
prolactin receptor
chr19_-_55691614 0.06 ENST00000592470.1
ENST00000354308.3
SYT5
synaptotagmin V
chr17_-_39661947 0.06 ENST00000590425.1
KRT13
keratin 13
chr5_+_148442844 0.05 ENST00000515519.1
CTC-529P8.1
CTC-529P8.1
chr1_+_206516200 0.05 ENST00000295713.5
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr12_-_123011536 0.05 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr11_+_117063295 0.05 ENST00000525478.1
ENST00000532062.1
SIDT2
SID1 transmembrane family, member 2
chr13_+_24144509 0.05 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr6_-_123958141 0.04 ENST00000334268.4
TRDN
triadin
chr17_-_39661849 0.04 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr1_+_18958008 0.04 ENST00000420770.2
ENST00000400661.3
PAX7
paired box 7
chr11_+_75273246 0.04 ENST00000526397.1
ENST00000529643.1
ENST00000525492.1
ENST00000530284.1
ENST00000532356.1
ENST00000524558.1
SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr11_-_122933043 0.04 ENST00000534624.1
ENST00000453788.2
ENST00000527387.1
HSPA8
heat shock 70kDa protein 8
chr22_+_36784632 0.03 ENST00000424761.1
RP4-633O19__A.1
RP4-633O19__A.1
chr19_-_14628645 0.03 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr22_+_41253080 0.03 ENST00000541156.1
ENST00000414396.1
ENST00000357137.4
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr12_-_53012343 0.03 ENST00000305748.3
KRT73
keratin 73

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.3 0.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.3 0.8 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 0.7 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.2 0.9 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.2 0.7 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2 0.8 GO:0010193 response to ozone(GO:0010193)
0.2 1.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.6 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.4 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 1.3 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1 0.3 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.3 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.7 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.4 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.8 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.6 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.3 GO:0021764 amygdala development(GO:0021764)
0.0 0.9 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.4 GO:0033590 response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.0 0.2 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.8 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 3.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.4 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.6 GO:0015074 DNA integration(GO:0015074)
0.0 0.6 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:1901631 positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.9 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:2000504 negative regulation of Fas signaling pathway(GO:1902045) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.8 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.5 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.2 GO:0035799 ureter maturation(GO:0035799)
0.0 0.4 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.5 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0030856 regulation of epithelial cell differentiation(GO:0030856)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 1.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 1.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.7 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.4 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 1.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0044305 calyx of Held(GO:0044305)
0.1 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.5 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.6 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 2.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 0.9 GO:0003883 CTP synthase activity(GO:0003883)
0.2 1.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.3 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 0.5 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.4 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.9 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.8 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0052811 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 1.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.7 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 3.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0004028 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0031852 beta-2 adrenergic receptor binding(GO:0031698) mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation