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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HOXD11_HOXA11

Z-value: 1.19

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Transcription factors associated with HOXD11_HOXA11

Gene Symbol Gene ID Gene Info
ENSG00000128713.11 homeobox D11
ENSG00000005073.5 homeobox A11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA11hg19_v2_chr7_-_27224795_27224840-0.396.1e-01Click!
HOXD11hg19_v2_chr2_+_176972000_176972025-0.049.6e-01Click!

Activity profile of HOXD11_HOXA11 motif

Sorted Z-values of HOXD11_HOXA11 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_58018269 1.03 ENST00000591035.1
Uncharacterized protein
chr6_-_15548591 0.74 ENST00000509674.1
dystrobrevin binding protein 1
chr6_+_32812568 0.67 ENST00000414474.1
proteasome (prosome, macropain) subunit, beta type, 9
chr14_+_39944025 0.66 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr17_-_46690839 0.64 ENST00000498634.2
homeobox B8
chr12_+_54384370 0.61 ENST00000504315.1
homeobox C6
chr9_-_130889990 0.53 ENST00000449878.1
prostaglandin E synthase 2
chr10_-_10504285 0.50 ENST00000602311.1
RP11-271F18.4
chr7_+_79763271 0.49 ENST00000442586.1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr1_-_204135450 0.48 ENST00000272190.8
ENST00000367195.2
renin
chr17_-_39646116 0.48 ENST00000328119.6
keratin 36
chr19_-_54618650 0.46 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr19_-_10420459 0.45 ENST00000403352.1
ENST00000403903.3
zinc finger, GATA-like protein 1
chr6_+_27114861 0.41 ENST00000377459.1
histone cluster 1, H2ah
chr2_-_228497888 0.39 ENST00000264387.4
ENST00000409066.1
chromosome 2 open reading frame 83
chr6_-_26189304 0.37 ENST00000340756.2
histone cluster 1, H4d
chr17_-_72772425 0.36 ENST00000578822.1
N-acetyltransferase 9 (GCN5-related, putative)
chr11_-_47447970 0.36 ENST00000298852.3
ENST00000530912.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr19_+_4402659 0.35 ENST00000301280.5
ENST00000585854.1
chromatin assembly factor 1, subunit A (p150)
chr19_-_19739321 0.35 ENST00000588461.1
lysophosphatidic acid receptor 2
chr12_-_118796910 0.34 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr7_+_35756186 0.34 ENST00000430518.1
AC018647.3
chr17_-_57158523 0.33 ENST00000581468.1
tripartite motif containing 37
chr6_+_71104588 0.33 ENST00000418403.1
RP11-462G2.1
chr3_+_184534994 0.33 ENST00000441141.1
ENST00000445089.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr11_+_34645791 0.32 ENST00000529527.1
ENST00000531728.1
ENST00000525253.1
ets homologous factor
chr14_-_25479811 0.31 ENST00000550887.1
syntaxin binding protein 6 (amisyn)
chr1_+_28527070 0.31 ENST00000596102.1
AL353354.2
chr5_+_121465207 0.31 ENST00000296600.4
zinc finger protein 474
chr15_-_85197501 0.30 ENST00000434634.2
WD repeat domain 73
chr12_+_43086018 0.30 ENST00000550177.1
RP11-25I15.3
chr10_+_96698406 0.29 ENST00000260682.6
cytochrome P450, family 2, subfamily C, polypeptide 9
chr1_+_23345943 0.28 ENST00000400181.4
ENST00000542151.1
lysine (K)-specific demethylase 1A
chr6_+_26156551 0.28 ENST00000304218.3
histone cluster 1, H1e
chr4_+_169013666 0.28 ENST00000359299.3
annexin A10
chr8_+_1993173 0.27 ENST00000523438.1
myomesin 2
chr19_+_41281282 0.27 ENST00000263369.3
melanoma inhibitory activity
chr4_+_86396321 0.27 ENST00000503995.1
Rho GTPase activating protein 24
chr15_-_76304731 0.27 ENST00000394907.3
neuregulin 4
chr14_-_51027838 0.26 ENST00000555216.1
mitogen-activated protein kinase kinase kinase kinase 5
chr9_-_35658007 0.26 ENST00000602361.1
RNA component of mitochondrial RNA processing endoribonuclease
chr2_+_220306238 0.26 ENST00000435853.1
SPEG complex locus
chr7_-_130080977 0.26 ENST00000223208.5
centrosomal protein 41kDa
chr19_-_54619006 0.25 ENST00000391759.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr7_+_35756092 0.25 ENST00000458087.3
AC018647.3
chr19_-_36233332 0.25 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGF-like family receptor 1
chr1_+_62439037 0.25 ENST00000545929.1
InaD-like (Drosophila)
chr21_+_17792672 0.25 ENST00000602620.1
long intergenic non-protein coding RNA 478
chr12_+_34175398 0.25 ENST00000538927.1
ALG10, alpha-1,2-glucosyltransferase
chr4_+_86396265 0.25 ENST00000395184.1
Rho GTPase activating protein 24
chr4_+_146539415 0.24 ENST00000281317.5
methylmalonic aciduria (cobalamin deficiency) cblA type
chr16_+_15031300 0.24 ENST00000328085.6
nuclear pore complex interacting protein family, member A1
chr1_+_23345930 0.24 ENST00000356634.3
lysine (K)-specific demethylase 1A
chr9_+_137979506 0.24 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
olfactomedin 1
chr12_-_118796971 0.23 ENST00000542902.1
TAO kinase 3
chr11_-_74204692 0.23 ENST00000528085.1
lipoyl(octanoyl) transferase 2 (putative)
chr10_-_103599591 0.23 ENST00000348850.5
Kv channel interacting protein 2
chr1_+_92545862 0.23 ENST00000370382.3
ENST00000342818.3
BTB (POZ) domain containing 8
chr4_-_129491686 0.23 ENST00000514265.1
RP11-184M15.1
chr6_+_13272904 0.22 ENST00000379335.3
ENST00000379329.1
phosphatase and actin regulator 1
chr19_-_22018966 0.22 ENST00000599906.1
ENST00000354959.4
zinc finger protein 43
chr17_-_28257080 0.22 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr5_+_61874562 0.22 ENST00000334994.5
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr22_+_30821732 0.22 ENST00000355143.4
mitochondrial fission process 1
chr8_+_1993152 0.22 ENST00000262113.4
myomesin 2
chr20_-_45530365 0.22 ENST00000414085.1
RP11-323C15.2
chr11_+_4510109 0.22 ENST00000307632.3
olfactory receptor, family 52, subfamily K, member 1
chr2_+_181988560 0.21 ENST00000424170.1
ENST00000435411.1
AC104820.2
chr1_-_154909329 0.21 ENST00000368467.3
phosphomevalonate kinase
chr12_-_71551868 0.21 ENST00000247829.3
tetraspanin 8
chr18_+_70536215 0.20 ENST00000578967.1
RP11-676J15.1
chr3_-_52188397 0.20 ENST00000474012.1
ENST00000296484.2
POC1 centriolar protein A
chr1_+_120254510 0.20 ENST00000369409.4
phosphoglycerate dehydrogenase
chr11_+_127140956 0.20 ENST00000608214.1
RP11-480C22.1
chr16_-_12062333 0.20 ENST00000597717.1
Uncharacterized protein
chr1_-_12679171 0.19 ENST00000606790.1
RP11-474O21.5
chr11_+_120039685 0.19 ENST00000530303.1
ENST00000319763.1
Uncharacterized protein
chr22_+_22723969 0.19 ENST00000390295.2
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr7_+_128784712 0.19 ENST00000289407.4
tetraspanin 33
chr17_-_48450534 0.19 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
mitochondrial ribosomal protein L27
chr15_+_93749295 0.19 ENST00000599897.1
AC112693.2
chr11_-_47447767 0.19 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr19_-_5785630 0.19 ENST00000586012.1
ENST00000590343.1
Uncharacterized protein
dihydrouridine synthase 3-like (S. cerevisiae)
chr2_+_109204909 0.19 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr16_-_48281305 0.18 ENST00000356608.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr7_-_138666053 0.18 ENST00000440172.1
ENST00000422774.1
KIAA1549
chr14_-_38028689 0.18 ENST00000553425.1
RP11-356O9.2
chr19_+_19626531 0.18 ENST00000507754.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr9_-_130829588 0.18 ENST00000373078.4
nuclear apoptosis inducing factor 1
chr11_-_62358972 0.18 ENST00000278279.3
terminal uridylyl transferase 1, U6 snRNA-specific
chr2_-_207023918 0.18 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr5_-_138534071 0.18 ENST00000394817.2
SIL1 nucleotide exchange factor
chr17_-_41132410 0.18 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr6_+_12290586 0.17 ENST00000379375.5
endothelin 1
chr1_-_230991747 0.17 ENST00000523410.1
chromosome 1 open reading frame 198
chr20_+_36405665 0.17 ENST00000373469.1
catenin, beta like 1
chr2_-_176046391 0.17 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr19_+_54619125 0.17 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
pre-mRNA processing factor 31
chr9_+_44868935 0.17 ENST00000448436.2
RP11-160N1.10
chr2_+_28618532 0.17 ENST00000545753.1
FOS-like antigen 2
chr11_+_34664014 0.17 ENST00000527935.1
ets homologous factor
chr8_+_107738240 0.17 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chr16_+_66613351 0.17 ENST00000379486.2
ENST00000268595.2
CKLF-like MARVEL transmembrane domain containing 2
chr7_-_110174754 0.16 ENST00000435466.1
AC003088.1
chr16_-_4852915 0.16 ENST00000322048.7
rogdi homolog (Drosophila)
chr4_-_178169927 0.16 ENST00000512516.1
Uncharacterized protein
chr12_+_76653682 0.16 ENST00000553247.1
RP11-54A9.1
chr2_+_242750274 0.16 ENST00000405370.1
sialidase 4
chr9_+_116263778 0.16 ENST00000394646.3
regulator of G-protein signaling 3
chr9_+_70856397 0.16 ENST00000360171.6
COBW domain containing 3
chr17_-_62340581 0.16 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
testis expressed 2
chr10_-_74283694 0.16 ENST00000398763.4
ENST00000418483.2
ENST00000489666.2
mitochondrial calcium uptake 1
chr6_+_25754927 0.16 ENST00000377905.4
ENST00000439485.2
solute carrier family 17, member 4
chr10_+_98741041 0.16 ENST00000286067.2
chromosome 10 open reading frame 12
chrX_+_149867681 0.16 ENST00000438018.1
ENST00000436701.1
myotubularin related protein 1
chr1_+_52682052 0.16 ENST00000371591.1
zinc finger, FYVE domain containing 9
chrX_-_135962923 0.15 ENST00000565438.1
RNA binding motif protein, X-linked
chr5_+_61874696 0.15 ENST00000491184.2
leucine rich repeat containing 70
chr3_+_173116225 0.15 ENST00000457714.1
neuroligin 1
chr4_+_144354644 0.15 ENST00000512843.1
GRB2-associated binding protein 1
chr14_-_69444957 0.15 ENST00000556571.1
ENST00000553659.1
ENST00000555616.1
actinin, alpha 1
chr21_+_30673091 0.15 ENST00000447177.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr16_+_14805546 0.15 ENST00000552140.1
nuclear pore complex interacting protein family, member A3
chr1_+_110993795 0.15 ENST00000271331.3
prokineticin 1
chr8_-_107782463 0.15 ENST00000311955.3
actin-binding Rho activating protein
chr4_-_156787425 0.15 ENST00000537611.2
acid-sensing (proton-gated) ion channel family member 5
chr9_-_133814455 0.15 ENST00000448616.1
fibrinogen C domain containing 1
chr4_+_56814968 0.15 ENST00000422247.2
centrosomal protein 135kDa
chr11_+_126173647 0.15 ENST00000263579.4
decapping enzyme, scavenger
chr16_-_21663950 0.15 ENST00000268389.4
immunoglobulin superfamily, member 6
chr12_-_71148413 0.15 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
protein tyrosine phosphatase, receptor type, R
chr3_+_174158732 0.15 ENST00000434257.1
N-acetylated alpha-linked acidic dipeptidase-like 2
chr7_-_41742697 0.15 ENST00000242208.4
inhibin, beta A
chr10_+_13652047 0.14 ENST00000601460.1
Uncharacterized protein
chr13_-_46626847 0.14 ENST00000242848.4
ENST00000282007.3
zinc finger CCCH-type containing 13
chr11_-_1606513 0.14 ENST00000382171.2
keratin associated protein 5-1
chr9_+_105757590 0.14 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr12_-_62586543 0.14 ENST00000416284.3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr8_+_66955648 0.14 ENST00000522619.1
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr12_+_49961990 0.14 ENST00000551063.1
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr4_-_103998439 0.14 ENST00000503230.1
ENST00000503818.1
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr1_-_101360205 0.14 ENST00000450240.1
exostosin-like glycosyltransferase 2
chr12_+_130646999 0.14 ENST00000539839.1
ENST00000229030.4
frizzled family receptor 10
chr6_+_30029008 0.14 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
zinc ribbon domain containing 1
chr22_+_50981079 0.14 ENST00000609268.1
CTA-384D8.34
chr22_-_30642782 0.14 ENST00000249075.3
leukemia inhibitory factor
chr6_+_30687978 0.14 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr12_+_123465033 0.14 ENST00000454885.2
ADP-ribosylation-like factor 6 interacting protein 4
chr13_+_78315466 0.13 ENST00000314070.5
ENST00000462234.1
SLAIN motif family, member 1
chr12_+_76653611 0.13 ENST00000550380.1
RP11-54A9.1
chr19_-_45982076 0.13 ENST00000423698.2
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr15_-_99789736 0.13 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
tetratricopeptide repeat domain 23
chr12_-_71148357 0.13 ENST00000378778.1
protein tyrosine phosphatase, receptor type, R
chr8_-_38326139 0.13 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
fibroblast growth factor receptor 1
chr17_-_48450265 0.13 ENST00000507088.1
mitochondrial ribosomal protein L27
chr6_-_167797887 0.13 ENST00000476779.2
ENST00000460930.2
ENST00000397829.4
ENST00000366827.2
t-complex 10
chr1_-_155880672 0.13 ENST00000609492.1
ENST00000368322.3
Ras-like without CAAX 1
chr4_+_169633310 0.13 ENST00000510998.1
palladin, cytoskeletal associated protein
chr12_+_58176525 0.13 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
Ts translation elongation factor, mitochondrial
chr12_-_49418407 0.13 ENST00000526209.1
lysine (K)-specific methyltransferase 2D
chr11_-_62342375 0.13 ENST00000378019.3
eukaryotic translation elongation factor 1 gamma
chr17_+_38083977 0.13 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
chr8_-_38326119 0.13 ENST00000356207.5
ENST00000326324.6
fibroblast growth factor receptor 1
chr6_+_36839616 0.13 ENST00000359359.2
ENST00000510325.2
chromosome 6 open reading frame 89
chr17_-_34257731 0.13 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RAD52 motif 1
chr3_-_112127981 0.13 ENST00000486726.2
RP11-231E6.1
chr1_-_109399682 0.13 ENST00000369995.3
ENST00000370001.3
AKNA domain containing 1
chr6_+_88054530 0.13 ENST00000388923.4
chromosome 6 open reading frame 163
chr2_+_234602305 0.13 ENST00000406651.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr6_-_121655850 0.13 ENST00000422369.1
TBC1 domain family, member 32
chr8_+_77593448 0.13 ENST00000521891.2
zinc finger homeobox 4
chr5_-_125930929 0.12 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr2_+_138721850 0.12 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase
chr6_+_149539053 0.12 ENST00000451095.1
RP1-111D6.3
chr2_+_220143989 0.12 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr2_+_101591314 0.12 ENST00000450763.1
neuronal PAS domain protein 2
chr5_+_142286887 0.12 ENST00000451259.1
Rho GTPase activating protein 26
chr1_-_106161540 0.12 ENST00000420901.1
ENST00000610126.1
ENST00000435253.2
RP11-251P6.1
chr3_-_138048682 0.12 ENST00000383180.2
NME/NM23 family member 9
chr11_+_64001962 0.12 ENST00000309422.2
vascular endothelial growth factor B
chr5_-_36301984 0.12 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RAN binding protein 3-like
chr9_+_101705893 0.12 ENST00000375001.3
collagen, type XV, alpha 1
chr16_-_67965756 0.12 ENST00000571044.1
ENST00000571605.1
chymotrypsin-like
chr17_-_71410794 0.12 ENST00000424778.1
sidekick cell adhesion molecule 2
chr17_+_54230819 0.12 ENST00000318698.2
ENST00000566473.2
ankyrin-repeat and fibronectin type III domain containing 1
chr1_-_95391315 0.12 ENST00000545882.1
ENST00000415017.1
calponin 3, acidic
chr12_-_95510743 0.12 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chr1_+_948803 0.12 ENST00000379389.4
ISG15 ubiquitin-like modifier
chr11_-_104827425 0.12 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr10_+_47658234 0.12 ENST00000447511.2
ENST00000537271.1
anthrax toxin receptor-like
chr6_+_167584081 0.12 ENST00000366832.2
t-complex 10-like 2
chr12_-_49961883 0.12 ENST00000553173.1
ENST00000550165.1
ENST00000546244.1
ENST00000343810.4
microspherule protein 1
chr2_+_29336855 0.12 ENST00000404424.1
CAP-GLY domain containing linker protein family, member 4
chr6_+_55192267 0.12 ENST00000340465.2
GDNF family receptor alpha like
chr12_+_58087738 0.12 ENST00000552285.1
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr9_-_95244781 0.12 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
asporin
chr1_-_89736434 0.12 ENST00000370459.3
guanylate binding protein 5
chr4_-_76957214 0.11 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr15_-_101817492 0.11 ENST00000528346.1
ENST00000531964.1
VCP-interacting membrane protein
chr17_-_38545799 0.11 ENST00000577541.1
topoisomerase (DNA) II alpha 170kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD11_HOXA11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.3 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.4 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.5 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.2 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.9 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.2 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.2 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.0 GO:0061041 regulation of coagulation(GO:0050818) regulation of wound healing(GO:0061041)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.2 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.5 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.6 GO:0021516 grooming behavior(GO:0007625) dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.1 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.0 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.0 0.0 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.0 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.1 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0 0.1 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.3 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.0 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.8 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0034709 methylosome(GO:0034709)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.4 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.3 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0016160 amylase activity(GO:0016160)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.1 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.3 GO:0070990 snRNP binding(GO:0070990)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.0 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.0 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0045029 uridine nucleotide receptor activity(GO:0015065) UDP-activated nucleotide receptor activity(GO:0045029) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends