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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for HOXC9
Z-value: 1.22
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Transcription factors associated with HOXC9
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXC9 | hg19_v2_chr12_+_54393880_54393962 | -0.41 | 5.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_+_65266507 Show fit | 1.22 |
ENST00000544868.1
|
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) |
|
| chr6_-_52859046 Show fit | 1.19 |
ENST00000457564.1
ENST00000541324.1 ENST00000370960.1 |
glutathione S-transferase alpha 4 |
|
| chr3_+_149191723 Show fit | 0.91 |
ENST00000305354.4
|
transmembrane 4 L six family member 4 |
|
| chr2_+_38177575 Show fit | 0.82 |
ENST00000407257.1
ENST00000417700.2 ENST00000234195.3 ENST00000442857.1 |
regulator of microtubule dynamics 2 |
|
| chr16_-_66907139 Show fit | 0.80 |
ENST00000561579.2
|
NEDD8 activating enzyme E1 subunit 1 |
|
| chr4_+_155484103 Show fit | 0.67 |
ENST00000302068.4
|
fibrinogen beta chain |
|
| chr4_+_155484155 Show fit | 0.65 |
ENST00000509493.1
|
fibrinogen beta chain |
|
| chr15_+_52155001 Show fit | 0.65 |
ENST00000544199.1
|
tropomodulin 3 (ubiquitous) |
|
| chr1_-_197115818 Show fit | 0.63 |
ENST00000367409.4
ENST00000294732.7 |
asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
|
| chr1_+_241695424 Show fit | 0.62 |
ENST00000366558.3
ENST00000366559.4 |
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXC9
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:1901685 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.1 | 1.3 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 0.9 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.1 | 0.8 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.0 | 0.7 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.2 | 0.6 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.1 | 0.6 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.1 | 0.6 | GO:1990034 | cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034) |
| 0.0 | 0.6 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.0 | 0.6 | GO:0002643 | regulation of tolerance induction(GO:0002643) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 0.7 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 0.0 | 0.7 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 0.6 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.0 | 0.6 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.0 | 0.6 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.5 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 0.4 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.0 | 0.3 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.0 | 0.3 | GO:0097165 | nuclear stress granule(GO:0097165) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.1 | 0.9 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.3 | 0.8 | GO:0019781 | NEDD8 activating enzyme activity(GO:0019781) |
| 0.1 | 0.7 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 0.6 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.1 | 0.6 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.0 | 0.6 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 0.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 0.5 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.1 | 0.5 | GO:0047493 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.4 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 1.3 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.9 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.0 | 0.7 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.7 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.5 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.5 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.0 | 0.5 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.5 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.5 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |