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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HOXC13

Z-value: 1.44

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Transcription factors associated with HOXC13

Gene Symbol Gene ID Gene Info
ENSG00000123364.3 homeobox C13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC13hg19_v2_chr12_+_54332535_54332636-0.019.9e-01Click!

Activity profile of HOXC13 motif

Sorted Z-values of HOXC13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_53207842 1.96 ENST00000458244.2
keratin 4
chr9_+_67977438 1.35 ENST00000456982.1
Protein LOC644249
chr20_-_52687059 1.27 ENST00000371435.2
ENST00000395961.3
breast carcinoma amplified sequence 1
chr4_-_155533787 1.16 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr16_-_66907139 1.14 ENST00000561579.2
NEDD8 activating enzyme E1 subunit 1
chr2_+_201390843 1.11 ENST00000357799.4
ENST00000409203.3
shugoshin-like 2 (S. pombe)
chr8_-_95274536 1.06 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr3_+_158449972 0.85 ENST00000486568.1
major facilitator superfamily domain containing 1
chr4_+_95679072 0.83 ENST00000515059.1
bone morphogenetic protein receptor, type IB
chr6_-_130031358 0.81 ENST00000368149.2
Rho GTPase activating protein 18
chr1_+_219347203 0.80 ENST00000366927.3
lysophospholipase-like 1
chr19_+_21106081 0.80 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
zinc finger protein 85
chr2_+_172778952 0.76 ENST00000392584.1
ENST00000264108.4
histone acetyltransferase 1
chr3_-_123339343 0.72 ENST00000578202.1
myosin light chain kinase
chr1_-_150208498 0.72 ENST00000314136.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_+_219347186 0.71 ENST00000366928.5
lysophospholipase-like 1
chr6_+_134274322 0.70 ENST00000367871.1
ENST00000237264.4
TBP-like 1
chr1_+_174128639 0.69 ENST00000251507.4
RAB GTPase activating protein 1-like
chr9_+_40028620 0.68 ENST00000426179.1
AL353791.1
chr3_-_179169181 0.67 ENST00000497513.1
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr13_+_34392185 0.67 ENST00000380071.3
replication factor C (activator 1) 3, 38kDa
chr1_-_150208412 0.66 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_-_74639886 0.66 ENST00000156626.7
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr14_-_80678512 0.65 ENST00000553968.1
deiodinase, iodothyronine, type II
chr16_+_53483983 0.65 ENST00000544545.1
retinoblastoma-like 2 (p130)
chr2_+_161993465 0.64 ENST00000457476.1
TRAF family member-associated NFKB activator
chr4_+_141178440 0.64 ENST00000394205.3
short coiled-coil protein
chr14_-_50319482 0.64 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
nuclear export mediator factor
chr1_+_174128704 0.63 ENST00000457696.1
RAB GTPase activating protein 1-like
chrM_+_8366 0.63 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr4_+_48485341 0.63 ENST00000273861.4
solute carrier family 10, member 4
chr5_-_79287060 0.61 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
metaxin 3
chr4_-_148605265 0.60 ENST00000541232.1
ENST00000322396.6
protein arginine methyltransferase 10 (putative)
chr5_+_35852797 0.60 ENST00000508941.1
interleukin 7 receptor
chr3_-_160117035 0.59 ENST00000489004.1
ENST00000496589.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr14_-_88200641 0.59 ENST00000556168.1
RP11-1152H15.1
chr7_+_90012986 0.58 ENST00000416322.1
claudin 12
chr4_+_128702969 0.58 ENST00000508776.1
ENST00000439123.2
heat shock 70kDa protein 4-like
chr7_-_16872932 0.58 ENST00000419572.2
ENST00000412973.1
anterior gradient 2
chr7_-_69062391 0.57 ENST00000436600.2
RP5-942I16.1
chr2_+_33359687 0.54 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr8_+_101170563 0.53 ENST00000520508.1
ENST00000388798.2
sperm associated antigen 1
chr21_+_25801041 0.53 ENST00000453784.2
ENST00000423581.1
AP000476.1
chr13_+_103451399 0.51 ENST00000257336.1
ENST00000448849.2
basic, immunoglobulin-like variable motif containing
chr14_-_50319758 0.51 ENST00000298310.5
nuclear export mediator factor
chr2_+_33359646 0.50 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr4_+_119200215 0.50 ENST00000602573.1
small nucleolar RNA host gene 8 (non-protein coding)
chr6_-_52628271 0.50 ENST00000493422.1
glutathione S-transferase alpha 2
chr11_+_107643129 0.50 ENST00000447610.1
Uncharacterized protein
chr7_+_64838712 0.49 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
zinc finger protein 92
chr13_+_34392200 0.49 ENST00000434425.1
replication factor C (activator 1) 3, 38kDa
chr11_+_101785727 0.47 ENST00000263468.8
KIAA1377
chr14_-_92333873 0.46 ENST00000435962.2
tandem C2 domains, nuclear
chr10_+_51549498 0.45 ENST00000358559.2
ENST00000298239.6
microseminoprotein, beta-
chr1_-_150208320 0.45 ENST00000534220.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr6_+_88182643 0.45 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr12_-_64062583 0.44 ENST00000542209.1
dpy-19-like 2 (C. elegans)
chr3_-_195310802 0.44 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr1_-_150208363 0.44 ENST00000436748.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr9_-_35361262 0.44 ENST00000599954.1
HCG17281; PRO0038; Uncharacterized protein
chr6_+_151358048 0.43 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr20_-_52687030 0.43 ENST00000411563.1
breast carcinoma amplified sequence 1
chr6_-_11807277 0.43 ENST00000379415.2
androgen-dependent TFPI-regulating protein
chr15_+_71185148 0.43 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr1_-_169680745 0.43 ENST00000236147.4
selectin L
chr7_-_27169801 0.41 ENST00000511914.1
homeobox A4
chr15_+_71184931 0.41 ENST00000560369.1
ENST00000260382.5
leucine rich repeat containing 49
chr7_+_129710350 0.40 ENST00000335420.5
ENST00000463413.1
kelch domain containing 10
chr8_+_35649365 0.40 ENST00000437887.1
Uncharacterized protein
chr18_+_3466248 0.39 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
chr2_+_138721850 0.39 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase
chr1_+_17559776 0.39 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
peptidyl arginine deiminase, type I
chr9_-_69229650 0.38 ENST00000416428.1
COBW domain containing 6
chr3_+_113667354 0.38 ENST00000491556.1
zinc finger, DHHC-type containing 23
chrX_-_38186775 0.37 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
retinitis pigmentosa GTPase regulator
chr1_+_174128536 0.37 ENST00000357444.6
ENST00000367689.3
RAB GTPase activating protein 1-like
chr4_+_119199904 0.37 ENST00000602483.1
ENST00000602819.1
small nucleolar RNA host gene 8 (non-protein coding)
chr15_+_77224045 0.37 ENST00000320963.5
ENST00000394883.3
reticulocalbin 2, EF-hand calcium binding domain
chr15_+_77223960 0.36 ENST00000394885.3
reticulocalbin 2, EF-hand calcium binding domain
chr7_-_152373216 0.36 ENST00000359321.1
X-ray repair complementing defective repair in Chinese hamster cells 2
chr4_+_119199864 0.36 ENST00000602414.1
ENST00000602520.1
small nucleolar RNA host gene 8 (non-protein coding)
chr3_+_99986036 0.34 ENST00000471098.1
TBC1 domain family, member 23
chr6_+_168434678 0.34 ENST00000496008.1
kinesin family member 25
chr8_-_17555164 0.34 ENST00000297488.6
microtubule associated tumor suppressor 1
chr17_+_17685422 0.34 ENST00000395774.1
retinoic acid induced 1
chr1_-_17231271 0.33 ENST00000606899.1
RP11-108M9.6
chr2_+_161993412 0.33 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr10_-_113943447 0.33 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
glycerol-3-phosphate acyltransferase, mitochondrial
chr14_+_97925151 0.33 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
chr1_+_90460661 0.33 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
zinc finger protein 326
chr3_+_101498269 0.32 ENST00000491511.2
neurexophilin and PC-esterase domain family, member 3
chr12_+_102514019 0.32 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARP1 binding protein
chr10_+_30723533 0.31 ENST00000413724.1
mitogen-activated protein kinase kinase kinase 8
chr3_-_98241760 0.31 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
claudin domain containing 1
chr17_+_29664830 0.30 ENST00000444181.2
ENST00000417592.2
neurofibromin 1
chr6_+_88117683 0.30 ENST00000369562.4
UPF0704 protein C6orf165
chr19_-_20748614 0.30 ENST00000596797.1
zinc finger protein 737
chr4_+_175204818 0.30 ENST00000503780.1
centrosomal protein 44kDa
chr11_+_63449045 0.29 ENST00000354497.4
reticulon 3
chr1_+_213224572 0.29 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr7_-_104909435 0.29 ENST00000357311.3
SRSF protein kinase 2
chr3_-_123339418 0.29 ENST00000583087.1
myosin light chain kinase
chr3_-_112320749 0.29 ENST00000610103.1
RP11-572C15.6
chr7_+_23719749 0.29 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
family with sequence similarity 221, member A
chr10_+_94352956 0.28 ENST00000260731.3
kinesin family member 11
chr7_-_30066233 0.28 ENST00000222803.5
FK506 binding protein 14, 22 kDa
chr1_-_150208291 0.28 ENST00000533654.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr3_-_46037299 0.28 ENST00000296137.2
FYVE and coiled-coil domain containing 1
chrY_+_14958970 0.28 ENST00000453031.1
ubiquitin specific peptidase 9, Y-linked
chr15_-_44069741 0.28 ENST00000319359.3
elongation factor RNA polymerase II-like 3
chr7_-_64023441 0.28 ENST00000309683.6
zinc finger protein 680
chr12_-_4647606 0.28 ENST00000261250.3
ENST00000541014.1
ENST00000545746.1
ENST00000542080.1
chromosome 12 open reading frame 4
chr16_-_46865286 0.28 ENST00000285697.4
chromosome 16 open reading frame 87
chr18_-_73967160 0.27 ENST00000579714.1
RP11-94B19.7
chrX_+_41583408 0.27 ENST00000302548.4
G protein-coupled receptor 82
chr7_-_25219897 0.26 ENST00000283905.3
ENST00000409280.1
ENST00000415598.1
chromosome 7 open reading frame 31
chr2_+_27760247 0.26 ENST00000447166.1
Uncharacterized protein
chr6_+_10585979 0.26 ENST00000265012.4
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr18_-_46895066 0.26 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
dymeclin
chr15_+_69373210 0.26 ENST00000435479.1
ENST00000559870.1
long intergenic non-protein coding RNA 277
RP11-809H16.5
chr5_-_19142450 0.25 ENST00000504827.1
RP11-124N3.3
chr5_+_56471592 0.25 ENST00000511209.1
GC-rich promoter binding protein 1
chr12_-_78934441 0.25 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1
chr15_+_85523671 0.24 ENST00000310298.4
ENST00000557957.1
phosphodiesterase 8A
chr13_-_20077417 0.24 ENST00000382978.1
ENST00000400230.2
ENST00000255310.6
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr1_+_47603109 0.23 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
cytochrome P450, family 4, subfamily A, polypeptide 22
chr4_+_124571409 0.23 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
long intergenic non-protein coding RNA 1091
chr22_-_19435209 0.23 ENST00000546308.1
ENST00000541063.1
ENST00000399568.1
ENST00000333059.5
histone cell cycle regulator
chromosome 22 open reading frame 39
chr12_-_47473425 0.23 ENST00000550413.1
adhesion molecule with Ig-like domain 2
chr15_+_77713222 0.22 ENST00000558176.1
high mobility group 20A
chr5_+_138678131 0.22 ENST00000394795.2
ENST00000510080.1
poly(A) binding protein interacting protein 2
chr17_-_2415169 0.22 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
methyltransferase like 16
chr15_+_69854027 0.22 ENST00000498938.2
RP11-279F6.1
chr9_-_5304432 0.22 ENST00000416837.1
ENST00000308420.3
relaxin 2
chr2_-_86850949 0.22 ENST00000237455.4
ring finger protein 103
chr2_-_223520770 0.22 ENST00000536361.1
phenylalanyl-tRNA synthetase, beta subunit
chr7_-_32534850 0.22 ENST00000409952.3
ENST00000409909.3
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_-_50065882 0.21 ENST00000539688.1
Full-length cDNA clone CS0DK012YO09 of HeLa cells of Homo sapiens (human); Uncharacterized protein
chr4_-_69536346 0.21 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chrX_-_135338503 0.21 ENST00000370663.5
MAP7 domain containing 3
chr13_+_28813645 0.21 ENST00000282391.5
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr8_-_82608409 0.21 ENST00000518568.1
solute carrier family 10, member 5
chr15_+_77713299 0.21 ENST00000559099.1
high mobility group 20A
chr2_+_48010312 0.21 ENST00000540021.1
mutS homolog 6
chr17_-_76824975 0.20 ENST00000586066.2
ubiquitin specific peptidase 36
chr17_-_74639730 0.20 ENST00000589992.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr17_+_43861680 0.20 ENST00000314537.5
corticotropin releasing hormone receptor 1
chr7_+_64838786 0.20 ENST00000450302.2
zinc finger protein 92
chr1_+_206858232 0.20 ENST00000294981.4
mitogen-activated protein kinase-activated protein kinase 2
chrX_-_100129128 0.19 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NADPH oxidase 1
chr4_-_175204765 0.19 ENST00000513696.1
ENST00000503293.1
F-box protein 8
chr3_+_122513642 0.19 ENST00000261038.5
disrupted in renal carcinoma 2
chr19_+_29456034 0.19 ENST00000589921.1
long intergenic non-protein coding RNA 906
chr17_-_46806540 0.19 ENST00000290295.7
homeobox B13
chr13_-_103451307 0.19 ENST00000376004.4
KDEL (Lys-Asp-Glu-Leu) containing 1
chr19_+_50084561 0.19 ENST00000246794.5
proline rich Gla (G-carboxyglutamic acid) 2
chr1_-_55266926 0.18 ENST00000371276.4
tetratricopeptide repeat domain 22
chr2_+_162016916 0.18 ENST00000405852.1
TRAF family member-associated NFKB activator
chr21_+_39628655 0.18 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr7_-_38389573 0.18 ENST00000390344.2
T cell receptor gamma variable 5
chr5_-_64920115 0.18 ENST00000381018.3
ENST00000274327.7
tripartite motif containing 23
chr4_-_170533723 0.18 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NIMA-related kinase 1
chr12_-_15815626 0.18 ENST00000540613.1
epidermal growth factor receptor pathway substrate 8
chr11_+_34999328 0.17 ENST00000526309.1
pyruvate dehydrogenase complex, component X
chr1_-_220220000 0.17 ENST00000366923.3
glutamyl-prolyl-tRNA synthetase
chr8_-_27850180 0.17 ENST00000380385.2
ENST00000301906.4
ENST00000354914.3
scavenger receptor class A, member 5 (putative)
chr14_+_24701870 0.17 ENST00000561035.1
ENST00000559409.1
ENST00000558865.1
ENST00000558279.1
guanosine monophosphate reductase 2
chr7_+_23749945 0.17 ENST00000354639.3
ENST00000531170.1
ENST00000444333.2
ENST00000428484.1
serine/threonine kinase 31
chr10_-_70287172 0.16 ENST00000539557.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr1_-_246670614 0.16 ENST00000403792.3
SET and MYND domain containing 3
chrX_+_78003204 0.16 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr6_-_36515177 0.16 ENST00000229812.7
serine/threonine kinase 38
chr17_-_39538550 0.16 ENST00000394001.1
keratin 34
chr17_-_3496171 0.16 ENST00000399756.4
transient receptor potential cation channel, subfamily V, member 1
chr7_+_134551583 0.15 ENST00000435928.1
caldesmon 1
chr16_-_2379688 0.15 ENST00000567910.1
ATP-binding cassette, sub-family A (ABC1), member 3
chr19_+_45409011 0.15 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chr12_+_70219052 0.15 ENST00000552032.2
ENST00000547771.2
myelin regulatory factor-like
chr1_+_222886694 0.14 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BRO1 domain and CAAX motif containing
chr2_+_172309634 0.14 ENST00000339506.3
DDB1 and CUL4 associated factor 17
chr4_+_170581213 0.14 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr12_-_11287243 0.14 ENST00000539585.1
taste receptor, type 2, member 30
chr5_+_5140436 0.14 ENST00000511368.1
ENST00000274181.7
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr2_+_162016827 0.13 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TRAF family member-associated NFKB activator
chr12_+_59194154 0.13 ENST00000548969.1
Protein LOC100506869
chr2_+_61372226 0.13 ENST00000426997.1
chromosome 2 open reading frame 74
chr13_-_81801115 0.13 ENST00000567258.1
long intergenic non-protein coding RNA 564
chr3_+_100428316 0.13 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TRK-fused gene
chr17_-_28257080 0.12 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr1_-_86174065 0.12 ENST00000370574.3
ENST00000431532.2
zinc finger, HIT-type containing 6
chr2_+_102953608 0.12 ENST00000311734.2
ENST00000409584.1
interleukin 1 receptor-like 1
chr4_+_175204865 0.12 ENST00000505124.1
centrosomal protein 44kDa
chr15_-_71184724 0.12 ENST00000560604.1
THAP domain containing 10
chr19_+_52102540 0.11 ENST00000601315.1
AC018755.17
chr1_+_40862501 0.11 ENST00000539317.1
small ArfGAP2
chr1_+_55107449 0.11 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
maestro heat-like repeat family member 7
chr16_-_18908196 0.10 ENST00000565324.1
ENST00000561947.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr11_+_94706804 0.10 ENST00000335080.5
lysine (K)-specific demethylase 4D
chr4_-_128887069 0.10 ENST00000541133.1
ENST00000296468.3
ENST00000513559.1
major facilitator superfamily domain containing 8
chr7_+_138915102 0.10 ENST00000486663.1
ubinuclein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 1.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 1.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.8 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.3 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.4 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.4 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 1.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.8 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 1.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.6 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.4 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:1903555 regulation of tumor necrosis factor production(GO:0032680) regulation of tumor necrosis factor superfamily cytokine production(GO:1903555)
0.1 0.2 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.6 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:2000646 lipid transport involved in lipid storage(GO:0010877) positive regulation of receptor catabolic process(GO:2000646)
0.0 1.4 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 2.6 GO:0043486 histone exchange(GO:0043486)
0.0 0.4 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.7 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.3 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.5 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475) mRNA methylation(GO:0080009)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0035933 glucocorticoid secretion(GO:0035933) regulation of glucocorticoid secretion(GO:2000849)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 1.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.9 GO:0042073 intraciliary transport(GO:0042073)
0.0 2.0 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.3 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 2.6 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.3 GO:0044609 DBIRD complex(GO:0044609)
0.1 1.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 1.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 2.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.7 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 1.1 GO:0050436 microfibril binding(GO:0050436)
0.2 1.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 1.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.7 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.2 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.2 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 2.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.2 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.2 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.2 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction