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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for HOXC11
Z-value: 1.09
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Transcription factors associated with HOXC11
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXC11 | hg19_v2_chr12_+_54366894_54366922 | 0.40 | 6.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_+_32812568 Show fit | 1.46 |
ENST00000414474.1
|
proteasome (prosome, macropain) subunit, beta type, 9 |
|
| chr17_+_58018269 Show fit | 1.28 |
ENST00000591035.1
|
Uncharacterized protein |
|
| chr11_-_115127611 Show fit | 0.83 |
ENST00000545094.1
|
cell adhesion molecule 1 |
|
| chr10_-_10504285 Show fit | 0.79 |
ENST00000602311.1
|
RP11-271F18.4 |
|
| chr1_-_204135450 Show fit | 0.78 |
ENST00000272190.8
ENST00000367195.2 |
renin |
|
| chrX_-_133792480 Show fit | 0.73 |
ENST00000359237.4
|
placenta-specific 1 |
|
| chr17_-_39646116 Show fit | 0.70 |
ENST00000328119.6
|
keratin 36 |
|
| chr7_+_35756186 Show fit | 0.68 |
ENST00000430518.1
|
AC018647.3 |
|
| chr4_+_169013666 Show fit | 0.64 |
ENST00000359299.3
|
annexin A10 |
|
| chr7_-_20826504 Show fit | 0.63 |
ENST00000418710.2
ENST00000361443.4 |
Sp8 transcription factor |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXC11
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 0.0 | 0.9 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.0 | 0.9 | GO:0045616 | regulation of keratinocyte differentiation(GO:0045616) |
| 0.2 | 0.8 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.2 | 0.8 | GO:0002018 | renin-angiotensin regulation of aldosterone production(GO:0002018) |
| 0.0 | 0.8 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.1 | 0.7 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 0.0 | 0.7 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
| 0.0 | 0.7 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.1 | 0.6 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.5 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.1 | 0.9 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 0.7 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.7 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.1 | 0.6 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.0 | 0.6 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 0.5 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.0 | 0.5 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.5 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.1 | 0.4 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.3 | 0.9 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.1 | 0.9 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.9 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.8 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.2 | 0.7 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
| 0.0 | 0.7 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 0.6 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.0 | 0.6 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.5 | GO:0005497 | androgen binding(GO:0005497) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.4 | ST STAT3 PATHWAY | STAT3 Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.0 | 0.9 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.9 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.8 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.7 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.5 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.4 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 0.4 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.4 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.3 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |