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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HOXB7

Z-value: 1.06

Motif logo

Transcription factors associated with HOXB7

Gene Symbol Gene ID Gene Info
ENSG00000260027.3 homeobox B7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB7hg19_v2_chr17_-_46688334_46688385-0.954.9e-02Click!

Activity profile of HOXB7 motif

Sorted Z-values of HOXB7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102668879 1.17 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr2_+_169926047 0.84 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr2_+_176972000 0.84 ENST00000249504.5
homeobox D11
chr11_+_57365150 0.68 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr7_-_105926058 0.68 ENST00000417537.1
nicotinamide phosphoribosyltransferase
chr3_-_185270342 0.67 ENST00000424591.2
lipase, member H
chr17_+_7758374 0.65 ENST00000301599.6
ENST00000574668.1
transmembrane protein 88
chr16_+_15596123 0.64 ENST00000452191.2
chromosome 16 open reading frame 45
chr17_+_58018269 0.59 ENST00000591035.1
Uncharacterized protein
chr14_+_101299520 0.57 ENST00000455531.1
maternally expressed 3 (non-protein coding)
chr11_-_74800799 0.57 ENST00000305159.3
olfactory receptor, family 2, subfamily AT, member 4
chrX_-_1331527 0.57 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
cytokine receptor-like factor 2
chr14_+_55034599 0.54 ENST00000392067.3
ENST00000357634.3
sterile alpha motif domain containing 4A
chr18_+_21464737 0.54 ENST00000586751.1
laminin, alpha 3
chr4_-_120243545 0.54 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr9_-_32526299 0.52 ENST00000379882.1
ENST00000379883.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chrX_+_1734051 0.52 ENST00000381229.4
ENST00000381233.3
acetylserotonin O-methyltransferase
chr12_+_43086018 0.50 ENST00000550177.1
RP11-25I15.3
chr4_-_141075330 0.49 ENST00000509479.2
mastermind-like 3 (Drosophila)
chr14_+_101295638 0.47 ENST00000523671.2
maternally expressed 3 (non-protein coding)
chr11_+_5646213 0.46 ENST00000429814.2
tripartite motif containing 34
chr15_-_60683326 0.45 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
annexin A2
chr10_+_13142075 0.42 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
optineurin
chr3_-_4927447 0.42 ENST00000449914.1
Uncharacterized protein
chr13_-_103719196 0.41 ENST00000245312.3
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr7_-_33080506 0.41 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
5'-nucleotidase, cytosolic IIIA
chr22_-_30642728 0.39 ENST00000403987.3
leukemia inhibitory factor
chr1_+_104615595 0.39 ENST00000418362.1
RP11-364B6.1
chr14_-_101295407 0.39 ENST00000596284.1
AL117190.2
chr4_+_169013666 0.38 ENST00000359299.3
annexin A10
chr22_-_30642782 0.37 ENST00000249075.3
leukemia inhibitory factor
chr14_+_35591858 0.37 ENST00000603544.1
KIAA0391
chr10_+_13141585 0.37 ENST00000378764.2
optineurin
chr22_+_46449674 0.36 ENST00000381051.2
hsa-mir-4763
chr12_+_40787194 0.36 ENST00000425730.2
ENST00000454784.4
mucin 19, oligomeric
chr10_+_13142225 0.35 ENST00000378747.3
optineurin
chr14_-_65769392 0.35 ENST00000555736.1
CTD-2509G16.5
chr4_+_26323764 0.35 ENST00000514730.1
ENST00000507574.1
recombination signal binding protein for immunoglobulin kappa J region
chr6_-_51952418 0.34 ENST00000371117.3
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr15_+_67418047 0.34 ENST00000540846.2
SMAD family member 3
chr3_+_173116225 0.34 ENST00000457714.1
neuroligin 1
chr4_-_44653636 0.33 ENST00000415895.4
ENST00000332990.5
Yip1 domain family, member 7
chr6_-_51952367 0.32 ENST00000340994.4
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr17_+_76494911 0.32 ENST00000598378.1
DNAH17 antisense RNA 1
chr10_+_13141441 0.32 ENST00000263036.5
optineurin
chr2_-_70780770 0.32 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
transforming growth factor, alpha
chr1_-_92952433 0.32 ENST00000294702.5
growth factor independent 1 transcription repressor
chr2_-_99917639 0.32 ENST00000308528.4
lysozyme G-like 1
chr11_-_111649074 0.31 ENST00000534218.1
RP11-108O10.2
chr10_+_47894572 0.31 ENST00000355876.5
family with sequence similarity 21, member B
chrX_-_77225135 0.31 ENST00000458128.1
phosphoglycerate mutase family member 4
chr4_-_72649763 0.30 ENST00000513476.1
group-specific component (vitamin D binding protein)
chr8_-_67874805 0.30 ENST00000563496.1
transcription factor 24
chr17_+_67498295 0.30 ENST00000589295.1
mitogen-activated protein kinase kinase 6
chr11_+_107650219 0.30 ENST00000398067.1
Uncharacterized protein
chr11_-_57194919 0.29 ENST00000532795.1
solute carrier family 43, member 3
chr3_-_108836945 0.29 ENST00000483760.1
MORC family CW-type zinc finger 1
chr1_+_101702417 0.29 ENST00000305352.6
sphingosine-1-phosphate receptor 1
chr12_-_91546926 0.29 ENST00000550758.1
decorin
chr9_-_73029540 0.28 ENST00000377126.2
Kruppel-like factor 9
chr5_+_67485704 0.28 ENST00000520762.1
Uncharacterized protein
chr4_-_77328458 0.28 ENST00000388914.3
ENST00000434846.2
coiled-coil domain containing 158
chr7_+_120629653 0.28 ENST00000450913.2
ENST00000340646.5
cadherin-like and PC-esterase domain containing 1
chr6_-_137539651 0.28 ENST00000543628.1
interferon gamma receptor 1
chr9_-_75488984 0.28 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
chr11_-_70507901 0.28 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SH3 and multiple ankyrin repeat domains 2
chr9_+_74729511 0.28 ENST00000545168.1
guanine deaminase
chr4_+_74301880 0.27 ENST00000395792.2
ENST00000226359.2
alpha-fetoprotein
chr1_-_224624730 0.27 ENST00000445239.1
WD repeat domain 26
chr16_+_67880574 0.27 ENST00000219169.4
nuclear transport factor 2
chr11_+_44117219 0.27 ENST00000532479.1
ENST00000527014.1
exostosin glycosyltransferase 2
chr10_+_5406935 0.27 ENST00000380433.3
urocortin 3
chr6_+_54172653 0.27 ENST00000370869.3
tubulointerstitial nephritis antigen
chr4_+_26324474 0.27 ENST00000514675.1
recombination signal binding protein for immunoglobulin kappa J region
chr16_+_82660635 0.26 ENST00000567445.1
ENST00000446376.2
cadherin 13
chr21_+_44313375 0.26 ENST00000354250.2
ENST00000340344.4
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr8_-_66750978 0.26 ENST00000523253.1
phosphodiesterase 7A
chr11_-_57194948 0.26 ENST00000533235.1
ENST00000526621.1
ENST00000352187.1
solute carrier family 43, member 3
chr3_+_191046810 0.26 ENST00000392455.3
ENST00000392456.3
coiled-coil domain containing 50
chr1_-_246357029 0.26 ENST00000391836.2
SET and MYND domain containing 3
chr16_+_20911174 0.26 ENST00000568663.1
LYR motif containing 1
chr19_-_56709162 0.26 ENST00000589938.1
ENST00000587032.2
ENST00000586855.2
zinc finger and SCAN domain containing 5B
chr12_+_28605426 0.26 ENST00000542801.1
coiled-coil domain containing 91
chr18_-_51750948 0.26 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr7_+_135777671 0.25 ENST00000445293.2
ENST00000435996.1
AC009784.3
chr10_+_47894023 0.25 ENST00000358474.5
family with sequence similarity 21, member B
chr8_-_116681123 0.25 ENST00000519674.1
trichorhinophalangeal syndrome I
chr14_+_45464658 0.25 ENST00000555874.1
family with sequence similarity 179, member B
chr1_+_152178320 0.25 ENST00000429352.1
RP11-107M16.2
chr13_-_41240717 0.25 ENST00000379561.5
forkhead box O1
chr12_+_59989918 0.25 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr5_+_140227357 0.24 ENST00000378122.3
protocadherin alpha 9
chr19_-_30199516 0.24 ENST00000591243.1
chromosome 19 open reading frame 12
chr2_-_154335300 0.24 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr14_+_77425972 0.23 ENST00000553613.1
RP11-7F17.7
chr10_+_124320156 0.23 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chrX_+_13707235 0.23 ENST00000464506.1
RAB9A, member RAS oncogene family
chr10_+_69869237 0.23 ENST00000373675.3
myopalladin
chr15_-_42343388 0.23 ENST00000399518.3
phospholipase A2, group IVE
chr16_-_68034470 0.23 ENST00000412757.2
dipeptidase 2
chr10_+_71561630 0.23 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
collagen, type XIII, alpha 1
chr1_+_112016414 0.23 ENST00000343534.5
ENST00000369718.3
chromosome 1 open reading frame 162
chr12_-_22063787 0.22 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr6_-_24720226 0.22 ENST00000378102.3
chromosome 6 open reading frame 62
chr10_+_24755416 0.22 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr14_-_24584138 0.22 ENST00000558280.1
ENST00000561028.1
neural retina leucine zipper
chr16_+_22501658 0.22 ENST00000415833.2
nuclear pore complex interacting protein family, member B5
chrX_-_110655306 0.22 ENST00000371993.2
doublecortin
chr6_-_66417107 0.22 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
eyes shut homolog (Drosophila)
chr21_-_33984456 0.22 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
Uncharacterized protein
chromosome 21 open reading frame 59
chr1_+_205473720 0.22 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr16_-_66583994 0.22 ENST00000564917.1
thymidine kinase 2, mitochondrial
chr1_-_91487806 0.21 ENST00000361321.5
zinc finger protein 644
chr12_+_113229737 0.21 ENST00000551052.1
ENST00000415485.3
rabphilin 3A homolog (mouse)
chr3_-_169587621 0.21 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
leucine rich repeat containing 31
chr1_+_244227632 0.21 ENST00000598000.1
Uncharacterized protein; cDNA FLJ42623 fis, clone BRACE3015894
chrX_-_106243294 0.21 ENST00000255495.7
MORC family CW-type zinc finger 4
chr12_-_11339543 0.21 ENST00000334266.1
taste receptor, type 2, member 42
chr17_-_7218631 0.21 ENST00000577040.2
ENST00000389167.5
ENST00000391950.3
G protein pathway suppressor 2
chr7_+_116654958 0.21 ENST00000449366.1
suppression of tumorigenicity 7
chr3_+_112929850 0.21 ENST00000464546.1
BOC cell adhesion associated, oncogene regulated
chr7_-_7782204 0.21 ENST00000418534.2
AC007161.5
chr19_+_35417939 0.21 ENST00000601142.1
ENST00000426813.2
zinc finger protein 30
chr7_-_3214287 0.21 ENST00000404626.3
LOC392621; Uncharacterized protein
chr17_+_44803922 0.20 ENST00000465370.1
N-ethylmaleimide-sensitive factor
chr19_+_54369608 0.20 ENST00000336967.3
myeloid-associated differentiation marker
chr14_-_54425475 0.20 ENST00000559642.1
bone morphogenetic protein 4
chr8_-_29208183 0.20 ENST00000240100.2
dual specificity phosphatase 4
chrX_+_1387693 0.20 ENST00000381529.3
ENST00000432318.2
ENST00000361536.3
ENST00000501036.2
ENST00000381524.3
ENST00000412290.1
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr12_+_78359999 0.20 ENST00000550503.1
neuron navigator 3
chr5_-_173217931 0.20 ENST00000522731.1
CTB-43E15.4
chr15_+_64680003 0.20 ENST00000261884.3
thyroid hormone receptor interactor 4
chr11_-_63376013 0.20 ENST00000540943.1
phospholipase A2, group XVI
chr4_+_69962212 0.20 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr17_-_46507567 0.20 ENST00000584924.1
src kinase associated phosphoprotein 1
chr2_-_200322723 0.19 ENST00000417098.1
SATB homeobox 2
chr12_+_59989791 0.19 ENST00000552432.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr11_-_61196858 0.19 ENST00000413184.2
cleavage and polyadenylation specific factor 7, 59kDa
chr2_+_120303717 0.19 ENST00000594371.1
Primary ciliary dyskinesia protein 1
chr10_-_51958906 0.19 ENST00000489640.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr2_+_27886330 0.19 ENST00000326019.6
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr5_+_131409476 0.19 ENST00000296871.2
colony stimulating factor 2 (granulocyte-macrophage)
chr12_+_123944070 0.18 ENST00000412157.2
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr11_+_35222629 0.18 ENST00000526553.1
CD44 molecule (Indian blood group)
chr2_+_39117010 0.18 ENST00000409978.1
Rho guanine nucleotide exchange factor (GEF) 33
chr1_+_66999799 0.18 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_+_2636522 0.18 ENST00000423196.1
IQ motif containing E
chr6_+_34204642 0.18 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr2_+_234826016 0.18 ENST00000324695.4
ENST00000433712.2
transient receptor potential cation channel, subfamily M, member 8
chr12_+_113229543 0.18 ENST00000447659.2
rabphilin 3A homolog (mouse)
chr16_-_63651939 0.18 ENST00000563855.1
ENST00000568932.1
ENST00000564290.1
RP11-368L12.1
chr1_+_224370873 0.18 ENST00000323699.4
ENST00000391877.3
delta(4)-desaturase, sphingolipid 1
chr21_+_43619796 0.18 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr9_+_105757590 0.17 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr3_-_145878954 0.17 ENST00000282903.5
ENST00000360060.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr3_-_108836977 0.17 ENST00000232603.5
MORC family CW-type zinc finger 1
chr19_+_41698927 0.17 ENST00000310054.4
cytochrome P450, family 2, subfamily S, polypeptide 1
chr1_-_178840157 0.17 ENST00000367629.1
ENST00000234816.2
angiopoietin-like 1
chr17_+_60447579 0.17 ENST00000450662.2
EF-hand calcium binding domain 3
chr8_+_12803176 0.17 ENST00000524591.2
KIAA1456
chr3_+_145782358 0.17 ENST00000422482.1
HCG1786590; PRO2533; Uncharacterized protein
chr20_+_10199566 0.17 ENST00000430336.1
synaptosomal-associated protein, 25kDa
chr12_+_101988627 0.17 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr18_+_3252206 0.17 ENST00000578562.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr7_-_120498357 0.17 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr12_+_101988774 0.17 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr8_+_28748765 0.17 ENST00000355231.5
homeobox containing 1
chr20_-_1309809 0.17 ENST00000360779.3
syndecan binding protein (syntenin) 2
chr17_-_46703826 0.17 ENST00000550387.1
ENST00000311177.5
homeobox B9
chr11_-_107729887 0.17 ENST00000525815.1
solute carrier family 35, member F2
chr3_-_183145873 0.16 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF.2 cell line derived transforming sequence-like 2
chr16_-_18462221 0.16 ENST00000528301.1
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr4_-_111558135 0.16 ENST00000394598.2
ENST00000394595.3
paired-like homeodomain 2
chrX_-_92928557 0.16 ENST00000373079.3
ENST00000475430.2
nucleosome assembly protein 1-like 3
chrX_+_36053908 0.16 ENST00000378660.2
calponin homology domain containing 2
chr8_-_116681686 0.16 ENST00000519815.1
trichorhinophalangeal syndrome I
chr13_+_108921977 0.16 ENST00000430559.1
ENST00000375887.4
tumor necrosis factor (ligand) superfamily, member 13b
chr18_+_22040620 0.16 ENST00000426880.2
histamine receptor H4
chr4_+_158493642 0.16 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
chr5_+_125758813 0.16 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chrX_-_106243451 0.16 ENST00000355610.4
ENST00000535534.1
MORC family CW-type zinc finger 4
chr19_+_20959098 0.15 ENST00000360204.5
ENST00000594534.1
zinc finger protein 66
chr17_-_69198295 0.15 ENST00000569074.1
cancer susceptibility candidate 17 (non-protein coding)
chr11_-_107729287 0.15 ENST00000375682.4
solute carrier family 35, member F2
chr14_-_23624511 0.15 ENST00000529705.2
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr16_-_88729473 0.15 ENST00000301012.3
ENST00000569177.1
mevalonate (diphospho) decarboxylase
chr5_-_58295712 0.15 ENST00000317118.8
phosphodiesterase 4D, cAMP-specific
chr6_-_90025011 0.15 ENST00000402938.3
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr5_+_125758865 0.15 ENST00000542322.1
ENST00000544396.1
GRAM domain containing 3
chr16_+_82660560 0.15 ENST00000268613.10
ENST00000565636.1
ENST00000431540.3
ENST00000428848.3
cadherin 13
chr2_+_157330081 0.15 ENST00000409674.1
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr14_-_68159152 0.15 ENST00000554035.1
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr12_+_113229452 0.15 ENST00000389385.4
rabphilin 3A homolog (mouse)
chr3_+_159943362 0.15 ENST00000326474.3
chromosome 3 open reading frame 80
chr8_-_67090825 0.14 ENST00000276571.3
corticotropin releasing hormone
chr12_+_21168630 0.14 ENST00000421593.2
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr8_+_104892639 0.14 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr2_+_219110149 0.14 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chr17_-_39203519 0.14 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr5_-_33297946 0.14 ENST00000510327.1
CTD-2066L21.3

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 0.5 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2 0.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.5 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.5 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 0.4 GO:0044115 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.3 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.6 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.5 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.6 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.8 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.2 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.4 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.2 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.2 GO:2000004 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.3 GO:0051414 response to cortisol(GO:0051414)
0.0 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.2 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.7 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.2 GO:0035993 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.4 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.2 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.9 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553) olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0097647 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) tolerance induction dependent upon immune response(GO:0002461) positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.7 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.3 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.2 GO:0033011 perinuclear theca(GO:0033011)
0.1 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146) filopodium tip(GO:0032433)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:1902710 GABA receptor complex(GO:1902710)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:1902912 pyruvate kinase complex(GO:1902912)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 0.7 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.3 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.3 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.4 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.4 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.5 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.0 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.2 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.6 GO:0008430 selenium binding(GO:0008430) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 1.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0016917 GABA receptor activity(GO:0016917)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling