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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HOXB4_LHX9

Z-value: 1.35

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Transcription factors associated with HOXB4_LHX9

Gene Symbol Gene ID Gene Info
HOXB4
ENSG00000182742.5 homeobox B4
LHX9
ENSG00000143355.11 LIM homeobox 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX9hg19_v2_chr1_+_197881592_1978816350.918.9e-02Click!
HOXB4hg19_v2_chr17_-_46657473_46657473-0.604.0e-01Click!

Activity profile of HOXB4_LHX9 motif

Sorted Z-values of HOXB4_LHX9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_5710919 4.01 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr19_+_54466179 2.80 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr11_-_327537 2.27 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr14_-_67878917 1.78 ENST00000216446.4
PLEK2
pleckstrin 2
chr19_-_3557570 1.65 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr20_-_56265680 1.14 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_-_126409159 1.03 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chrX_+_10126488 0.94 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr15_+_64680003 0.92 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr15_+_90735145 0.87 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr18_-_51750948 0.87 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr1_+_225600404 0.86 ENST00000366845.2
AC092811.1
AC092811.1
chr1_-_212965104 0.85 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1
NSL1, MIS12 kinetochore complex component
chr12_-_10022735 0.85 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr22_+_46476192 0.84 ENST00000443490.1
FLJ27365
hsa-mir-4763
chr2_+_182850743 0.81 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_+_182850551 0.80 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_-_121986923 0.80 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr12_+_38710555 0.79 ENST00000551464.1
ALG10B
ALG10B, alpha-1,2-glucosyltransferase
chr5_+_179135246 0.79 ENST00000508787.1
CANX
calnexin
chr14_+_24641820 0.78 ENST00000560501.1
REC8
REC8 meiotic recombination protein
chr14_+_24641062 0.76 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8
REC8 meiotic recombination protein
chr11_-_74800799 0.76 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr8_-_90769422 0.72 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1
RP11-37B2.1
chr4_-_120243545 0.71 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr9_+_22646189 0.65 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr5_+_89770664 0.64 ENST00000503973.1
ENST00000399107.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr16_-_66583994 0.62 ENST00000564917.1
TK2
thymidine kinase 2, mitochondrial
chr21_+_33671160 0.61 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chrX_-_77225135 0.55 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr18_-_47018869 0.54 ENST00000583036.1
ENST00000580261.1
RPL17
ribosomal protein L17
chr4_+_71091786 0.53 ENST00000317987.5
FDCSP
follicular dendritic cell secreted protein
chr1_+_151253991 0.53 ENST00000443959.1
ZNF687
zinc finger protein 687
chr17_-_19015945 0.53 ENST00000573866.2
SNORD3D
small nucleolar RNA, C/D box 3D
chr11_-_128894053 0.51 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr1_-_190446759 0.50 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr17_+_56833184 0.50 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr6_+_26402465 0.49 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr10_+_90660832 0.49 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr12_+_34175398 0.48 ENST00000538927.1
ALG10
ALG10, alpha-1,2-glucosyltransferase
chr11_-_107729287 0.48 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr11_-_63376013 0.47 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr2_+_234826016 0.46 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr10_+_24755416 0.46 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr11_-_107729887 0.45 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr7_+_116654958 0.45 ENST00000449366.1
ST7
suppression of tumorigenicity 7
chr6_-_32806506 0.44 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr7_+_129015671 0.44 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chr13_-_81801115 0.44 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chrX_-_18690210 0.43 ENST00000379984.3
RS1
retinoschisin 1
chr2_-_169887827 0.41 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr17_+_19091325 0.41 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr7_-_87856303 0.41 ENST00000394641.3
SRI
sorcin
chr15_+_89631647 0.41 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chr15_+_80351910 0.40 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr10_+_18549645 0.40 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr17_+_40118773 0.40 ENST00000472031.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr1_+_155278539 0.40 ENST00000447866.1
FDPS
farnesyl diphosphate synthase
chr20_-_1447547 0.39 ENST00000476071.1
NSFL1C
NSFL1 (p97) cofactor (p47)
chr8_+_39972170 0.39 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr16_+_15489603 0.38 ENST00000568766.1
ENST00000287594.7
RP11-1021N1.1
MPV17L
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chrX_+_1710484 0.37 ENST00000313871.3
ENST00000381261.3
AKAP17A
A kinase (PRKA) anchor protein 17A
chr1_+_155278625 0.37 ENST00000368356.4
ENST00000356657.6
FDPS
farnesyl diphosphate synthase
chr11_-_115127611 0.37 ENST00000545094.1
CADM1
cell adhesion molecule 1
chrX_+_84258832 0.37 ENST00000373173.2
APOOL
apolipoprotein O-like
chr10_+_6821545 0.36 ENST00000436383.1
LINC00707
long intergenic non-protein coding RNA 707
chr20_-_1447467 0.36 ENST00000353088.2
ENST00000350991.4
NSFL1C
NSFL1 (p97) cofactor (p47)
chr17_+_33914424 0.36 ENST00000590432.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr7_-_87856280 0.36 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chrX_+_36254051 0.36 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr8_-_90996459 0.36 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr18_-_47018769 0.35 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17
ribosomal protein L17
chr2_+_202047596 0.35 ENST00000286186.6
ENST00000360132.3
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr1_-_92952433 0.35 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr5_+_1225470 0.35 ENST00000324642.3
ENST00000296821.4
SLC6A18
solute carrier family 6 (neutral amino acid transporter), member 18
chr12_-_25348007 0.35 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr8_-_41166953 0.35 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr7_+_133812052 0.34 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr15_+_67418047 0.34 ENST00000540846.2
SMAD3
SMAD family member 3
chr7_-_150020750 0.34 ENST00000539352.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr5_+_40841276 0.34 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr14_+_35591928 0.34 ENST00000605870.1
ENST00000557404.3
KIAA0391
KIAA0391
chrX_-_110655306 0.33 ENST00000371993.2
DCX
doublecortin
chr4_-_119759795 0.33 ENST00000419654.2
SEC24D
SEC24 family member D
chr5_+_89770696 0.33 ENST00000504930.1
ENST00000514483.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr3_-_141747950 0.32 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr12_+_26348246 0.32 ENST00000422622.2
SSPN
sarcospan
chr7_-_150020578 0.32 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr10_+_99627889 0.32 ENST00000596005.1
GOLGA7B
Golgin subfamily A member 7B; cDNA FLJ43465 fis, clone OCBBF2036476
chr7_-_25702669 0.32 ENST00000446840.1
AC003090.1
AC003090.1
chr11_-_124670550 0.31 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr1_+_160370344 0.31 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr16_+_82068873 0.31 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr3_+_38537960 0.31 ENST00000453767.1
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr1_+_157963063 0.31 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL
kin of IRRE like (Drosophila)
chr8_-_90996837 0.30 ENST00000519426.1
ENST00000265433.3
NBN
nibrin
chr10_-_105845674 0.30 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr17_+_33914460 0.30 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr6_+_26402517 0.29 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr15_+_66679155 0.29 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr11_-_107729504 0.29 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr9_-_99540328 0.29 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510
zinc finger protein 510
chr18_-_47018897 0.29 ENST00000418495.1
RPL17
ribosomal protein L17
chr5_-_173217931 0.29 ENST00000522731.1
CTB-43E15.4
CTB-43E15.4
chr1_-_183538319 0.29 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr17_+_40118759 0.29 ENST00000393892.3
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr4_+_110749143 0.28 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr3_-_157221380 0.28 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr3_-_98619999 0.28 ENST00000449482.1
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr12_-_22063787 0.28 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr15_-_60683326 0.27 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2
annexin A2
chr5_+_129083772 0.27 ENST00000564719.1
KIAA1024L
KIAA1024-like
chr12_-_112123524 0.26 ENST00000327551.6
BRAP
BRCA1 associated protein
chr6_-_135818368 0.26 ENST00000367798.2
AHI1
Abelson helper integration site 1
chr6_+_42584847 0.26 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr15_+_48483736 0.26 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr3_-_87842631 0.26 ENST00000462792.1
RP11-451B8.1
RP11-451B8.1
chr4_-_70518941 0.26 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr20_-_33735070 0.26 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr19_-_14064114 0.26 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr19_+_4153598 0.25 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3
chr11_-_111649074 0.25 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr16_-_29934558 0.25 ENST00000568995.1
ENST00000566413.1
KCTD13
potassium channel tetramerization domain containing 13
chr14_+_103851712 0.25 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr12_+_93096619 0.24 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr18_+_21452804 0.24 ENST00000269217.6
LAMA3
laminin, alpha 3
chr2_+_27886330 0.24 ENST00000326019.6
SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chrX_-_15332665 0.24 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr2_+_202047843 0.24 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr2_+_149402989 0.24 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr3_-_157221357 0.23 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr14_+_55595762 0.23 ENST00000254301.9
LGALS3
lectin, galactoside-binding, soluble, 3
chr11_-_104827425 0.23 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr6_+_142623758 0.23 ENST00000541199.1
ENST00000435011.2
GPR126
G protein-coupled receptor 126
chr7_-_149158187 0.22 ENST00000247930.4
ZNF777
zinc finger protein 777
chr12_+_78359999 0.22 ENST00000550503.1
NAV3
neuron navigator 3
chr15_-_72523924 0.22 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
PKM
pyruvate kinase, muscle
chr14_-_104387888 0.22 ENST00000286953.3
C14orf2
chromosome 14 open reading frame 2
chr14_+_35591735 0.22 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
KIAA0391
chr3_-_20053741 0.22 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chr3_+_185431080 0.22 ENST00000296270.1
C3orf65
chromosome 3 open reading frame 65
chr8_-_124553437 0.21 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr17_+_33914276 0.21 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr5_+_40841410 0.21 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr2_-_225811747 0.21 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr17_+_67498538 0.21 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr9_+_88556444 0.21 ENST00000376040.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr18_+_60206744 0.21 ENST00000586834.1
ZCCHC2
zinc finger, CCHC domain containing 2
chr5_+_66300464 0.21 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr11_-_46408107 0.21 ENST00000433765.2
CHRM4
cholinergic receptor, muscarinic 4
chr18_+_21452964 0.21 ENST00000587184.1
LAMA3
laminin, alpha 3
chr19_-_36001113 0.21 ENST00000434389.1
DMKN
dermokine
chr1_-_57045228 0.20 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_+_152178320 0.20 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr6_+_31553978 0.20 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr4_+_158493642 0.20 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
RP11-364P22.1
chr20_+_18488137 0.20 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B
Sec23 homolog B (S. cerevisiae)
chr8_-_116504448 0.20 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr4_-_103749179 0.19 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_+_64798095 0.19 ENST00000332707.5
XPOT
exportin, tRNA
chr1_-_47184745 0.19 ENST00000544071.1
EFCAB14
EF-hand calcium binding domain 14
chr1_-_168464875 0.19 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr6_-_33663474 0.19 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr11_+_74811578 0.19 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr2_-_158345341 0.19 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr12_-_25150373 0.19 ENST00000549828.1
C12orf77
chromosome 12 open reading frame 77
chr9_+_125132803 0.18 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr10_-_105845536 0.18 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chr16_+_3184924 0.18 ENST00000574902.1
ENST00000396878.3
ZNF213
zinc finger protein 213
chr10_-_99030395 0.18 ENST00000355366.5
ENST00000371027.1
ARHGAP19
Rho GTPase activating protein 19
chr13_+_111837279 0.18 ENST00000467053.1
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr5_-_150473127 0.18 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr6_+_34204642 0.18 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr8_-_33424636 0.17 ENST00000256257.1
RNF122
ring finger protein 122
chr1_-_211307404 0.17 ENST00000367007.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr6_+_170151708 0.17 ENST00000592367.1
ENST00000590711.1
ENST00000366772.2
ENST00000592745.1
ENST00000392095.4
ENST00000366773.3
ENST00000586341.1
ENST00000418781.3
ENST00000588437.1
ERMARD
ER membrane-associated RNA degradation
chr17_-_42992856 0.17 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
GFAP
glial fibrillary acidic protein
chr16_+_3185125 0.17 ENST00000576416.1
ZNF213
zinc finger protein 213
chr2_-_88285309 0.17 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr14_+_35591858 0.17 ENST00000603544.1
KIAA0391
KIAA0391
chr10_+_5135981 0.17 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr15_+_62853562 0.17 ENST00000561311.1
TLN2
talin 2
chr13_-_36050819 0.17 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr13_-_30160925 0.16 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr9_-_28670283 0.16 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr1_-_8000872 0.16 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr7_+_102553430 0.16 ENST00000339431.4
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr22_-_32767017 0.16 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr10_-_28571015 0.16 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr5_-_119669160 0.16 ENST00000514240.1
CTC-552D5.1
CTC-552D5.1
chr8_+_105235572 0.16 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr4_+_25162253 0.15 ENST00000512921.1
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr14_+_23938891 0.15 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
NGDN
neuroguidin, EIF4E binding protein
chr17_+_4692230 0.15 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr18_-_3219847 0.15 ENST00000261606.7
MYOM1
myomesin 1
chr19_-_6424783 0.15 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr16_+_24549014 0.15 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr7_+_107224364 0.15 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr20_+_5731083 0.14 ENST00000445603.1
ENST00000442185.1
C20orf196
chromosome 20 open reading frame 196
chr3_-_142682178 0.14 ENST00000340634.3
PAQR9
progestin and adipoQ receptor family member IX

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB4_LHX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.2 0.8 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.4 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.6 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.6 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 2.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.4 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.3 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.8 GO:0006880 intracellular sequestering of iron ion(GO:0006880) negative regulation of heart rate(GO:0010459) sequestering of iron ion(GO:0097577)
0.1 0.3 GO:0070121 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.1 0.3 GO:0090244 negative regulation of B cell differentiation(GO:0045578) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 1.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.4 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 2.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.3 GO:0052360 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.5 GO:0050955 thermoception(GO:0050955)
0.1 0.8 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.2 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.1 0.2 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 4.2 GO:0070206 protein trimerization(GO:0070206)
0.1 0.3 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.4 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.5 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 1.0 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.2 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:0090402 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745) positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 1.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.8 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:1901295 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.0 GO:2000397 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.9 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.0 GO:0002765 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 1.0 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124) regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.9 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 0.9 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.8 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.8 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.8 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 1.0 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 2.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.1 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.0 4.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 2.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.6 GO:0097342 ripoptosome(GO:0097342)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 3.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.2 0.6 GO:0070996 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.2 0.7 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 0.8 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.6 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.4 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 1.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 1.0 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 3.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.2 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) mediator complex binding(GO:0036033)
0.0 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 4.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.0 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 1.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling