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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for HOXA6
Z-value: 1.42
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Transcription factors associated with HOXA6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXA6 | hg19_v2_chr7_-_27187393_27187393 | 0.56 | 4.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_41884620 Show fit | 3.59 |
ENST00000504870.1
|
long intergenic non-protein coding RNA 682 |
|
| chr10_-_10504285 Show fit | 2.97 |
ENST00000602311.1
|
RP11-271F18.4 |
|
| chr11_-_115127611 Show fit | 1.58 |
ENST00000545094.1
|
cell adhesion molecule 1 |
|
| chr11_-_8290263 Show fit | 1.31 |
ENST00000428101.2
|
LIM domain only 1 (rhombotin 1) |
|
| chr9_-_16253112 Show fit | 1.29 |
ENST00000380683.1
|
chromosome 9 open reading frame 92 |
|
| chr5_-_27038683 Show fit | 1.22 |
ENST00000511822.1
ENST00000231021.4 |
cadherin 9, type 2 (T1-cadherin) |
|
| chr7_-_27205136 Show fit | 1.22 |
ENST00000396345.1
ENST00000343483.6 |
homeobox A9 |
|
| chr16_-_51185149 Show fit | 1.20 |
ENST00000566102.1
ENST00000541611.1 |
spalt-like transcription factor 1 |
|
| chr7_+_129015484 Show fit | 1.19 |
ENST00000490911.1
|
adenosylhomocysteinase-like 2 |
|
| chr17_-_39093672 Show fit | 1.17 |
ENST00000209718.3
ENST00000436344.3 ENST00000485751.1 |
keratin 23 (histone deacetylase inducible) |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXA6
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.5 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.3 | 2.1 | GO:2000670 | positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 0.0 | 2.0 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
| 0.0 | 2.0 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.2 | 1.7 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.3 | 1.6 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.0 | 1.5 | GO:0070268 | cornification(GO:0070268) |
| 0.2 | 1.4 | GO:0072619 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.1 | 1.4 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.1 | 1.2 | GO:0042118 | endothelial cell activation(GO:0042118) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.2 | 1.3 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.8 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 0.7 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.2 | 0.6 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.0 | 0.5 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 0.4 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.1 | 0.3 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 0.0 | 0.3 | GO:0070369 | Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.0 | 0.3 | GO:0016013 | syntrophin complex(GO:0016013) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.2 | 2.1 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.1 | 2.0 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 1.9 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.2 | 1.7 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 1.6 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 0.7 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.3 | 0.6 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 0.6 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.1 | 0.5 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 0.8 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.6 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 0.3 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 0.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.2 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.1 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.7 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 0.6 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 0.5 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.4 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.0 | 0.3 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.2 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |