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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HNF4A

Z-value: 2.56

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Transcription factors associated with HNF4A

Gene Symbol Gene ID Gene Info
ENSG00000101076.12 hepatocyte nuclear factor 4 alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF4Ahg19_v2_chr20_+_43029911_430299410.981.7e-02Click!

Activity profile of HNF4A motif

Sorted Z-values of HNF4A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_119056178 4.46 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZ domain containing 3
chr2_-_228244013 4.03 ENST00000304568.3
transmembrane 4 L six family member 20
chr17_-_7082861 3.88 ENST00000269299.3
asialoglycoprotein receptor 1
chr1_+_145727681 3.68 ENST00000417171.1
ENST00000451928.2
PDZ domain containing 1
chr17_+_4675175 3.20 ENST00000270560.3
transmembrane 4 L six family member 5
chr20_+_57875457 3.16 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
endothelin 3
chr1_+_48688357 3.13 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr16_+_29690358 2.29 ENST00000395384.4
ENST00000562473.1
quinolinate phosphoribosyltransferase
chr20_-_7921090 2.18 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr19_-_36304201 2.17 ENST00000301175.3
proline dehydrogenase (oxidase) 2
chr13_+_113777105 2.09 ENST00000409306.1
ENST00000375551.3
ENST00000375559.3
coagulation factor X
chr1_-_197036364 2.02 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr3_-_158390282 1.94 ENST00000264265.3
latexin
chr7_-_37956409 1.92 ENST00000436072.2
secreted frizzled-related protein 4
chr12_+_121416437 1.83 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1 homeobox A
chr19_-_10687948 1.73 ENST00000592285.1
adaptor-related protein complex 1, mu 2 subunit
chr12_+_56114151 1.71 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
retinol dehydrogenase 5 (11-cis/9-cis)
chr1_+_241695670 1.60 ENST00000366557.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_241695424 1.57 ENST00000366558.3
ENST00000366559.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_+_44502597 1.56 ENST00000260649.6
ENST00000409387.1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr17_-_7082668 1.54 ENST00000573083.1
ENST00000574388.1
asialoglycoprotein receptor 1
chr18_+_13382553 1.51 ENST00000586222.1
low density lipoprotein receptor class A domain containing 4
chr17_-_27503770 1.49 ENST00000533112.1
myosin XVIIIA
chr19_+_41949054 1.47 ENST00000378187.2
chromosome 19 open reading frame 69
chr12_+_56114189 1.46 ENST00000548082.1
retinol dehydrogenase 5 (11-cis/9-cis)
chr1_+_100435315 1.46 ENST00000370155.3
ENST00000465289.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr1_-_211848899 1.41 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NIMA-related kinase 2
chr1_+_94883991 1.38 ENST00000370214.4
ATP-binding cassette, sub-family D (ALD), member 3
chr19_-_42758040 1.33 ENST00000593944.1
Ets2 repressor factor
chr1_-_15911510 1.31 ENST00000375826.3
agmatine ureohydrolase (agmatinase)
chr1_+_45274154 1.30 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTB (POZ) domain containing 19
chr2_+_128293323 1.30 ENST00000389524.4
ENST00000428314.1
myosin VIIB
chrX_+_66764375 1.28 ENST00000374690.3
androgen receptor
chr2_+_44502630 1.26 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr16_+_21244986 1.25 ENST00000311620.5
ankyrin repeat and sterile alpha motif domain containing 4B
chr1_+_94883931 1.21 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ATP-binding cassette, sub-family D (ALD), member 3
chr1_+_100435535 1.20 ENST00000427993.2
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr16_-_57514277 1.13 ENST00000562008.1
ENST00000567214.1
docking protein 4
chr3_-_53878644 1.10 ENST00000481668.1
ENST00000467802.1
choline dehydrogenase
chr12_+_56075330 1.09 ENST00000394252.3
methyltransferase like 7B
chr5_-_42811986 1.05 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr19_-_48867171 1.05 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
transmembrane protein 143
chr15_-_63448973 1.01 ENST00000462430.1
ribosomal protein S27-like
chr14_+_64680854 1.01 ENST00000458046.2
spectrin repeat containing, nuclear envelope 2
chr5_-_79950371 1.00 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
dihydrofolate reductase
chr19_-_10687907 1.00 ENST00000589348.1
adaptor-related protein complex 1, mu 2 subunit
chr13_+_50656307 0.96 ENST00000378180.4
deleted in lymphocytic leukemia 1 (non-protein coding)
chrX_-_77041685 0.95 ENST00000373344.5
ENST00000395603.3
alpha thalassemia/mental retardation syndrome X-linked
chr19_-_10687983 0.95 ENST00000587069.1
adaptor-related protein complex 1, mu 2 subunit
chr3_+_37284668 0.91 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
golgin A4
chr3_-_120400960 0.91 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr6_+_80341000 0.90 ENST00000369838.4
SH3 domain binding glutamic acid-rich protein like 2
chr19_-_35625765 0.90 ENST00000591633.1
leucine-rich repeat LGI family, member 4
chr11_-_64660916 0.89 ENST00000413053.1
microRNA 194-2
chr11_-_71781096 0.88 ENST00000535087.1
ENST00000535838.1
nuclear mitotic apparatus protein 1
chr12_-_53594227 0.86 ENST00000550743.2
integrin, beta 7
chr10_+_96698406 0.86 ENST00000260682.6
cytochrome P450, family 2, subfamily C, polypeptide 9
chr16_-_16317321 0.86 ENST00000205557.7
ENST00000575728.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr6_-_86099898 0.85 ENST00000455071.1
RP11-30P6.6
chr2_+_241544834 0.85 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
G protein-coupled receptor 35
chr20_+_57875758 0.79 ENST00000395654.3
endothelin 3
chr12_-_121973974 0.78 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
lysine (K)-specific demethylase 2B
chr3_-_124653579 0.76 ENST00000478191.1
ENST00000311075.3
mucin 13, cell surface associated
chr11_-_8816375 0.75 ENST00000530580.1
suppression of tumorigenicity 5
chr3_+_63898275 0.72 ENST00000538065.1
ataxin 7
chr12_+_121416340 0.72 ENST00000257555.6
ENST00000400024.2
HNF1 homeobox A
chr2_-_61389240 0.71 ENST00000606876.1
RP11-493E12.1
chr12_+_121416489 0.70 ENST00000541395.1
ENST00000544413.1
HNF1 homeobox A
chr11_+_64073699 0.69 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr2_-_74648702 0.69 ENST00000518863.1
chromosome 2 open reading frame 81
chr6_-_149806105 0.67 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
zinc finger CCCH-type containing 12D
chr12_-_39837192 0.66 ENST00000361961.3
ENST00000395670.3
kinesin family member 21A
chr16_-_3350614 0.65 ENST00000268674.2
tigger transposable element derived 7
chr7_-_15601595 0.65 ENST00000342526.3
alkylglycerol monooxygenase
chr19_+_751122 0.65 ENST00000215582.6
mitotic spindle positioning
chr19_-_48867291 0.64 ENST00000435956.3
transmembrane protein 143
chr19_-_35626104 0.63 ENST00000310123.3
ENST00000392225.3
leucine-rich repeat LGI family, member 4
chr17_+_1646130 0.62 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr6_+_43028182 0.62 ENST00000394058.1
kinesin light chain 4
chr20_+_56136136 0.62 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr1_+_110163682 0.59 ENST00000358729.4
adenosine monophosphate deaminase 2
chr2_+_159313452 0.57 ENST00000389757.3
ENST00000389759.3
plakophilin 4
chr3_-_125775629 0.57 ENST00000383598.2
solute carrier family 41, member 3
chr11_-_65381643 0.57 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr2_+_191792376 0.56 ENST00000409428.1
ENST00000409215.1
glutaminase
chr5_-_173043591 0.56 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
biorientation of chromosomes in cell division 1
chr11_-_73720122 0.56 ENST00000426995.2
uncoupling protein 3 (mitochondrial, proton carrier)
chr17_+_73606766 0.55 ENST00000578462.1
myosin XVB pseudogene
chr17_+_27071002 0.55 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TNF receptor-associated factor 4
chr8_-_79717163 0.54 ENST00000520269.1
interleukin 7
chr10_-_116444371 0.53 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr1_+_110163709 0.52 ENST00000369840.2
ENST00000527846.1
adenosine monophosphate deaminase 2
chr16_+_24857309 0.51 ENST00000565769.1
ENST00000449109.2
ENST00000424767.2
ENST00000545376.1
ENST00000569520.1
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr16_+_24857552 0.51 ENST00000568579.1
ENST00000567758.1
ENST00000569071.1
ENST00000539472.1
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr5_-_1801408 0.50 ENST00000505818.1
mitochondrial ribosomal protein L36
chr16_+_29840929 0.50 ENST00000566252.1
major vault protein
chr4_+_109541722 0.50 ENST00000394667.3
ENST00000502534.1
ribosomal protein L34
chr18_-_61034743 0.49 ENST00000406396.3
3-ketodihydrosphingosine reductase
chr11_-_45939374 0.49 ENST00000533151.1
ENST00000241041.3
peroxisomal biogenesis factor 16
chr17_-_44896047 0.47 ENST00000225512.5
wingless-type MMTV integration site family, member 3
chr5_+_79950463 0.46 ENST00000265081.6
mutS homolog 3
chr3_+_63897605 0.46 ENST00000487717.1
ataxin 7
chr2_-_150444116 0.45 ENST00000428879.1
ENST00000422782.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr2_-_219433014 0.45 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
ubiquitin specific peptidase 37
chr1_-_11863171 0.45 ENST00000376592.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr7_+_33765593 0.45 ENST00000311067.3
HCG1643653; Uncharacterized protein
chr3_-_125313934 0.44 ENST00000296220.5
oxysterol binding protein-like 11
chr14_+_39735411 0.43 ENST00000603904.1
cTAGE family member 5 isoform 4
chr20_+_57875658 0.43 ENST00000371025.3
endothelin 3
chr1_-_26197744 0.43 ENST00000374296.3
progestin and adipoQ receptor family member VII
chr4_+_109541772 0.42 ENST00000506397.1
ENST00000394668.2
ribosomal protein L34
chr2_+_74648848 0.42 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WD repeat domain 54
chr12_-_118810688 0.40 ENST00000542532.1
ENST00000392533.3
TAO kinase 3
chr9_-_35685452 0.39 ENST00000607559.1
tropomyosin 2 (beta)
chr1_-_177939348 0.39 ENST00000464631.2
SEC16 homolog B (S. cerevisiae)
chr5_+_136070614 0.39 ENST00000502421.1
CTB-1I21.1
chr19_-_14201776 0.38 ENST00000269724.5
sterile alpha motif domain containing 1
chr14_-_39572279 0.38 ENST00000536508.1
Sec23 homolog A (S. cerevisiae)
chr2_-_61389168 0.37 ENST00000607743.1
ENST00000605902.1
RP11-493E12.1
chr2_-_62733476 0.37 ENST00000335390.5
transmembrane protein 17
chr20_-_36156293 0.37 ENST00000373537.2
ENST00000414542.2
bladder cancer associated protein
chr20_-_36156125 0.37 ENST00000397135.1
ENST00000397137.1
bladder cancer associated protein
chr19_+_7660716 0.36 ENST00000160298.4
ENST00000446248.2
calmodulin regulated spectrin-associated protein family, member 3
chr12_+_47617284 0.36 ENST00000549630.1
ENST00000551777.1
PC-esterase domain containing 1B
chr5_-_42812143 0.36 ENST00000514985.1
selenoprotein P, plasma, 1
chr6_+_116937636 0.36 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
radial spoke head 4 homolog A (Chlamydomonas)
chr10_+_99349450 0.35 ENST00000370640.3
chromosome 10 open reading frame 62
chr1_+_180601139 0.35 ENST00000367590.4
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr11_-_118868682 0.35 ENST00000526453.1
RP11-110I1.12
chr4_+_109541740 0.34 ENST00000394665.1
ribosomal protein L34
chr5_-_16509101 0.34 ENST00000399793.2
family with sequence similarity 134, member B
chr20_-_44485835 0.34 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
acyl-CoA thioesterase 8
chr16_-_87970122 0.34 ENST00000309893.2
carbonic anhydrase VA, mitochondrial
chr14_+_100485712 0.34 ENST00000544450.2
Enah/Vasp-like
chr11_+_1855645 0.33 ENST00000381968.3
ENST00000381978.3
synaptotagmin VIII
chr17_-_38256973 0.33 ENST00000246672.3
nuclear receptor subfamily 1, group D, member 1
chr5_-_32444828 0.32 ENST00000265069.8
zinc finger RNA binding protein
chr2_-_222436988 0.30 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPH receptor A4
chr2_-_219134343 0.30 ENST00000447885.1
ENST00000420660.1
angio-associated, migratory cell protein
chr5_+_133842243 0.29 ENST00000515627.2
AC005355.2
chr12_-_46384334 0.29 ENST00000369367.3
ENST00000266589.6
ENST00000395453.2
ENST00000395454.2
SR-related CTD-associated factor 11
chr1_-_23694794 0.29 ENST00000374608.3
zinc finger protein 436
chr17_-_28618867 0.29 ENST00000394819.3
ENST00000577623.1
bleomycin hydrolase
chr15_+_50716576 0.28 ENST00000560297.1
ENST00000307179.4
ENST00000396444.3
ENST00000433963.1
ENST00000425032.3
ubiquitin specific peptidase 8
chr16_+_66600294 0.27 ENST00000535705.1
ENST00000332695.7
ENST00000336328.6
ENST00000528324.1
ENST00000531885.1
ENST00000529506.1
ENST00000457188.2
ENST00000533666.1
ENST00000533953.1
ENST00000379500.2
ENST00000328020.6
CKLF-like MARVEL transmembrane domain containing 1
chrX_-_152939780 0.27 ENST00000370142.1
ENST00000393831.2
ENST00000447676.2
pregnancy up-regulated nonubiquitous CaM kinase
chr9_-_27005686 0.27 ENST00000380055.5
leucine rich repeat containing 19
chr11_-_73720276 0.27 ENST00000348534.4
uncoupling protein 3 (mitochondrial, proton carrier)
chr4_+_113152881 0.27 ENST00000274000.5
adaptor-related protein complex 1 associated regulatory protein
chr2_-_28113217 0.27 ENST00000444339.2
ribokinase
chr2_+_219433281 0.27 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr1_-_151138323 0.26 ENST00000368908.5
LysM, putative peptidoglycan-binding, domain containing 1
chr20_+_44486246 0.26 ENST00000255152.2
ENST00000454862.2
zinc finger, SWIM-type containing 3
chr2_-_27603582 0.26 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr10_+_18689637 0.26 ENST00000377315.4
calcium channel, voltage-dependent, beta 2 subunit
chr6_+_43739697 0.25 ENST00000230480.6
vascular endothelial growth factor A
chr5_-_102455801 0.25 ENST00000508629.1
ENST00000399004.2
gypsy retrotransposon integrase 1
chr6_+_131148538 0.25 ENST00000541421.2
small leucine-rich protein 1
chr6_+_143999185 0.24 ENST00000542769.1
ENST00000397980.3
phosphatase and actin regulator 2
chr1_+_110163202 0.22 ENST00000531203.1
ENST00000256578.3
adenosine monophosphate deaminase 2
chr16_+_19429018 0.22 ENST00000542583.2
transmembrane channel-like 5
chr4_-_88244049 0.21 ENST00000328546.4
hydroxysteroid (17-beta) dehydrogenase 13
chr6_+_143999072 0.21 ENST00000440869.2
ENST00000367582.3
ENST00000451827.2
phosphatase and actin regulator 2
chr4_-_109541539 0.21 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34 antisense RNA 1 (head to head)
chr10_-_96829246 0.21 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr11_-_64163297 0.20 ENST00000457725.1
AP003774.6
chr2_-_219134822 0.20 ENST00000444053.1
ENST00000248450.4
angio-associated, migratory cell protein
chr16_+_24857162 0.19 ENST00000347898.3
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr3_-_52002194 0.18 ENST00000466412.1
poly(rC) binding protein 4
chr2_-_159313214 0.18 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
coiled-coil domain containing 148
chr14_-_39572345 0.18 ENST00000548032.2
ENST00000556092.1
ENST00000557280.1
ENST00000545328.2
ENST00000553970.1
Sec23 homolog A (S. cerevisiae)
chr20_-_36156264 0.18 ENST00000445723.1
ENST00000414080.1
bladder cancer associated protein
chr12_+_67663056 0.18 ENST00000545606.1
cullin-associated and neddylation-dissociated 1
chr16_-_47007545 0.17 ENST00000317089.5
DnaJ (Hsp40) homolog, subfamily A, member 2
chr12_-_95009837 0.17 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr4_-_88244010 0.17 ENST00000302219.6
hydroxysteroid (17-beta) dehydrogenase 13
chr4_+_113152978 0.17 ENST00000309703.6
adaptor-related protein complex 1 associated regulatory protein
chr19_+_4639514 0.16 ENST00000327473.4
tumor necrosis factor, alpha-induced protein 8-like 1
chr11_-_45939565 0.16 ENST00000525192.1
ENST00000378750.5
peroxisomal biogenesis factor 16
chr12_-_21757774 0.16 ENST00000261195.2
glycogen synthase 2 (liver)
chr2_+_73441350 0.15 ENST00000389501.4
SMYD family member 5
chr19_-_15235906 0.15 ENST00000600984.1
ilvB (bacterial acetolactate synthase)-like
chr1_-_43751230 0.15 ENST00000523677.1
chromosome 1 open reading frame 210
chr6_+_30882108 0.14 ENST00000541562.1
ENST00000421263.1
valyl-tRNA synthetase 2, mitochondrial
chr14_+_23790690 0.14 ENST00000556821.1
poly(A) binding protein, nuclear 1
chr20_+_36661910 0.14 ENST00000373433.4
regulation of nuclear pre-mRNA domain containing 1B
chr14_-_23446021 0.14 ENST00000553592.1
ajuba LIM protein
chr15_+_101142722 0.13 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
ankyrin repeat and SOCS box containing 7
chr3_-_141868357 0.13 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
transcription factor Dp-2 (E2F dimerization partner 2)
chr13_+_76334498 0.13 ENST00000534657.1
LIM domain 7
chr18_+_42260059 0.12 ENST00000426838.4
SET binding protein 1
chr17_+_4853442 0.12 ENST00000522301.1
enolase 3 (beta, muscle)
chr14_+_32476072 0.12 ENST00000556949.1
Uncharacterized protein
chr17_+_77704681 0.12 ENST00000328313.5
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr1_-_155270770 0.11 ENST00000392414.3
pyruvate kinase, liver and RBC
chr1_+_6508100 0.11 ENST00000461727.1
espin
chr14_+_77648167 0.10 ENST00000554346.1
ENST00000298351.4
transmembrane protein 63C
chr8_+_104831554 0.10 ENST00000408894.2
regulating synaptic membrane exocytosis 2
chr14_+_23790655 0.10 ENST00000397276.2
poly(A) binding protein, nuclear 1
chr6_+_147527103 0.09 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF4A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0035623 renal glucose absorption(GO:0035623)
0.9 4.4 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.6 5.5 GO:0046874 quinolinate metabolic process(GO:0046874)
0.5 2.7 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.5 1.9 GO:0010966 regulation of phosphate transport(GO:0010966) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4 1.8 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.4 1.3 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.4 4.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.4 1.5 GO:1903028 positive regulation of opsonization(GO:1903028)
0.4 2.8 GO:0015811 L-cystine transport(GO:0015811)
0.3 1.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.3 2.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.3 2.2 GO:0006562 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.3 2.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 1.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.3 1.3 GO:1904970 brush border assembly(GO:1904970)
0.3 1.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.2 1.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.2 0.5 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.2 1.3 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.2 0.6 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.2 0.8 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 0.6 GO:1904640 response to methionine(GO:1904640)
0.2 1.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.2 1.2 GO:0015798 myo-inositol transport(GO:0015798)
0.2 0.9 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.9 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.4 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 1.3 GO:0032264 IMP salvage(GO:0032264)
0.1 0.8 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 1.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 3.7 GO:0015879 carnitine transport(GO:0015879)
0.1 0.3 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.1 0.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.5 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.6 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) negative regulation of plasminogen activation(GO:0010757)
0.1 0.3 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 3.1 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 1.9 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.7 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 3.2 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 5.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 3.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.3 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.8 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.3 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 1.5 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.6 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.5 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.5 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.9 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.5 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.7 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.2 0.9 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 0.5 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.4 GO:0001534 radial spoke(GO:0001534)
0.1 3.7 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.7 GO:0055028 cortical microtubule(GO:0055028)
0.1 2.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 3.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:1990909 Wnt signalosome(GO:1990909)
0.0 6.4 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 2.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 2.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 3.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.9 4.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.7 3.7 GO:0005124 scavenger receptor binding(GO:0005124)
0.7 2.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.6 5.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.5 2.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.5 2.7 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.5 4.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.5 2.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.4 2.8 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.3 1.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 3.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 1.0 GO:0015616 DNA translocase activity(GO:0015616)
0.2 1.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.2 0.6 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2 1.0 GO:0051870 methotrexate binding(GO:0051870)
0.2 0.5 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 1.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 3.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.3 GO:0005497 androgen binding(GO:0005497)
0.1 0.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.4 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 1.0 GO:0008494 translation activator activity(GO:0008494)
0.0 1.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.5 GO:0043531 ADP binding(GO:0043531)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 3.1 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.0 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 1.9 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 3.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 4.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 3.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 3.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 3.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 2.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.4 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 2.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 4.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 3.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell