Project
A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for HMX3
Z-value: 1.07
Motif logo
Transcription factors associated with HMX3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HMX3 | hg19_v2_chr10_+_124895472_124895508 | 0.57 | 4.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_149192475 Show fit | 1.65 |
ENST00000465758.1
|
transmembrane 4 L six family member 4 |
|
| chr17_-_64225508 Show fit | 1.58 |
ENST00000205948.6
|
apolipoprotein H (beta-2-glycoprotein I) |
|
| chr3_+_186330712 Show fit | 1.49 |
ENST00000411641.2
ENST00000273784.5 |
alpha-2-HS-glycoprotein |
|
| chr1_+_241695670 Show fit | 0.83 |
ENST00000366557.4
|
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
|
| chr1_+_241695424 Show fit | 0.79 |
ENST00000366558.3
ENST00000366559.4 |
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
|
| chr5_+_138611798 Show fit | 0.76 |
ENST00000502394.1
|
matrin 3 |
|
| chr11_+_65266507 Show fit | 0.61 |
ENST00000544868.1
|
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) |
|
| chr1_-_86861660 Show fit | 0.60 |
ENST00000486215.1
|
outer dense fiber of sperm tails 2-like |
|
| chr8_-_17752912 Show fit | 0.60 |
ENST00000398054.1
ENST00000381840.2 |
fibrinogen-like 1 |
|
| chr21_+_17909594 Show fit | 0.59 |
ENST00000441820.1
ENST00000602280.1 |
long intergenic non-protein coding RNA 478 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HMX3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 0.2 | 1.6 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.1 | 1.6 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.0 | 1.3 | GO:0042246 | tissue regeneration(GO:0042246) |
| 0.0 | 1.2 | GO:1901685 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.0 | 0.9 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.2 | 0.7 | GO:0090293 | nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250) |
| 0.1 | 0.7 | GO:0006574 | valine catabolic process(GO:0006574) |
| 0.0 | 0.7 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.0 | 0.7 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 1.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 1.6 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 1.3 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 1.0 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 0.5 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.1 | 0.5 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.0 | 0.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.5 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 0.5 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.6 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.1 | 1.6 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 1.2 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.2 | 0.9 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.1 | 0.8 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.2 | 0.7 | GO:1902122 | chenodeoxycholic acid binding(GO:1902122) |
| 0.2 | 0.6 | GO:0036134 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 0.1 | 0.6 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.0 | 0.6 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.6 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.7 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.4 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.3 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 1.2 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 1.1 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 1.1 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 0.7 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.7 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.6 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 0.5 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.5 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |