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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HMX2

Z-value: 1.14

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Transcription factors associated with HMX2

Gene Symbol Gene ID Gene Info
HMX2
ENSG00000188816.3 H6 family homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX2hg19_v2_chr10_+_124907638_124907660-0.277.3e-01Click!

Activity profile of HMX2 motif

Sorted Z-values of HMX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_327537 1.41 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr11_+_5710919 1.26 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr22_+_50981079 1.19 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr15_-_60695071 0.84 ENST00000557904.1
ANXA2
annexin A2
chr19_-_3557570 0.62 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr6_-_27858570 0.60 ENST00000359303.2
HIST1H3J
histone cluster 1, H3j
chr10_-_126849626 0.59 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr15_+_101417919 0.52 ENST00000561338.1
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr1_-_202858227 0.51 ENST00000367262.3
RABIF
RAB interacting factor
chr14_+_101295638 0.51 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr14_-_101295407 0.50 ENST00000596284.1
AL117190.2
AL117190.2
chr18_+_68002675 0.50 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr6_-_26124138 0.49 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr19_+_9361606 0.49 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr9_-_14322319 0.48 ENST00000606230.1
NFIB
nuclear factor I/B
chr2_+_45168875 0.48 ENST00000260653.3
SIX3
SIX homeobox 3
chr1_+_209878182 0.47 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr20_+_42136308 0.46 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr10_-_22292675 0.42 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr1_-_110933611 0.42 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr11_+_110225855 0.41 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1
RP11-347E10.1
chr4_-_120243545 0.40 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr21_-_39705286 0.39 ENST00000414189.1
AP001422.3
AP001422.3
chrX_-_1331527 0.38 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
CRLF2
cytokine receptor-like factor 2
chr17_-_29641104 0.37 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr12_-_94673956 0.35 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr1_+_239882842 0.35 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr8_-_93978309 0.34 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr13_+_49551020 0.33 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr15_+_41056218 0.33 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr6_-_160209471 0.32 ENST00000539948.1
TCP1
t-complex 1
chr19_-_51568324 0.32 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
KLK13
kallikrein-related peptidase 13
chr3_+_38537960 0.32 ENST00000453767.1
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr9_+_26746951 0.32 ENST00000523363.1
RP11-18A15.1
RP11-18A15.1
chr18_+_76829441 0.31 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr4_-_159080806 0.30 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr11_+_60681346 0.30 ENST00000227525.3
TMEM109
transmembrane protein 109
chr6_+_77484663 0.30 ENST00000607287.1
RP11-354K4.2
RP11-354K4.2
chr14_+_55595762 0.29 ENST00000254301.9
LGALS3
lectin, galactoside-binding, soluble, 3
chr14_-_50864006 0.27 ENST00000216378.2
CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chrX_-_101186981 0.27 ENST00000458570.1
ZMAT1
zinc finger, matrin-type 1
chr8_+_32579271 0.27 ENST00000518084.1
NRG1
neuregulin 1
chr1_-_110933663 0.27 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr11_-_74442430 0.26 ENST00000376332.3
CHRDL2
chordin-like 2
chr11_-_64684672 0.26 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr12_-_49463753 0.26 ENST00000301068.6
RHEBL1
Ras homolog enriched in brain like 1
chr22_+_42095497 0.26 ENST00000401548.3
ENST00000540833.1
ENST00000400107.1
ENST00000300398.4
MEI1
meiosis inhibitor 1
chr4_+_156775910 0.25 ENST00000506072.1
ENST00000507590.1
TDO2
tryptophan 2,3-dioxygenase
chr17_-_15469590 0.25 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr9_+_130159433 0.25 ENST00000451404.1
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr12_-_112123524 0.25 ENST00000327551.6
BRAP
BRCA1 associated protein
chr20_-_47804894 0.24 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
STAU1
staufen double-stranded RNA binding protein 1
chr3_+_23847394 0.24 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr12_+_64798095 0.23 ENST00000332707.5
XPOT
exportin, tRNA
chr4_-_90759440 0.23 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr11_+_94277017 0.23 ENST00000358752.2
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chrX_+_36254051 0.22 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr2_+_211342400 0.22 ENST00000417946.1
ENST00000518043.1
ENST00000523702.1
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr1_+_182584314 0.22 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr4_+_70894130 0.22 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr8_+_32579321 0.21 ENST00000522402.1
NRG1
neuregulin 1
chr1_-_11918988 0.21 ENST00000376468.3
NPPB
natriuretic peptide B
chr3_+_145782358 0.21 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr10_-_49813090 0.21 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr17_-_29641084 0.21 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr11_-_128894053 0.20 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr3_+_185303962 0.20 ENST00000296257.5
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr10_-_95241951 0.20 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr3_-_187009646 0.20 ENST00000296280.6
ENST00000392470.2
ENST00000169293.6
ENST00000439271.1
ENST00000392472.2
ENST00000392475.2
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr11_-_18211042 0.20 ENST00000527671.1
RP11-113D6.6
Uncharacterized protein
chr10_+_12238171 0.20 ENST00000378900.2
ENST00000442050.1
CDC123
cell division cycle 123
chrX_+_1710484 0.20 ENST00000313871.3
ENST00000381261.3
AKAP17A
A kinase (PRKA) anchor protein 17A
chr5_-_43397184 0.20 ENST00000513525.1
CCL28
chemokine (C-C motif) ligand 28
chr2_-_145277569 0.19 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr12_-_122985067 0.19 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr6_-_26199499 0.19 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr12_-_72057571 0.19 ENST00000548100.1
ZFC3H1
zinc finger, C3H1-type containing
chr19_+_40877583 0.19 ENST00000596470.1
PLD3
phospholipase D family, member 3
chr15_+_54305101 0.19 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C
unc-13 homolog C (C. elegans)
chr11_+_64685026 0.18 ENST00000526559.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr12_-_49463620 0.18 ENST00000550675.1
RHEBL1
Ras homolog enriched in brain like 1
chr19_+_52772832 0.18 ENST00000593703.1
ENST00000601711.1
ENST00000599581.1
ZNF766
zinc finger protein 766
chr4_+_166248775 0.18 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chrX_+_134478706 0.17 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
ZNF449
zinc finger protein 449
chr5_+_61602236 0.17 ENST00000514082.1
ENST00000407818.3
KIF2A
kinesin heavy chain member 2A
chr20_+_5986756 0.17 ENST00000452938.1
CRLS1
cardiolipin synthase 1
chr3_-_194188956 0.17 ENST00000256031.4
ENST00000446356.1
ATP13A3
ATPase type 13A3
chr1_-_109399682 0.16 ENST00000369995.3
ENST00000370001.3
AKNAD1
AKNA domain containing 1
chr12_+_128399965 0.16 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr8_+_31496809 0.16 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chrX_+_36053908 0.16 ENST00000378660.2
CHDC2
calponin homology domain containing 2
chr5_-_58295712 0.15 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_151344172 0.15 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr19_-_52674896 0.15 ENST00000322146.8
ENST00000597065.1
ZNF836
zinc finger protein 836
chr4_+_83956312 0.15 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr4_-_69817481 0.15 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr3_-_79816965 0.15 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr19_-_3772209 0.15 ENST00000555978.1
ENST00000555633.1
RAX2
retina and anterior neural fold homeobox 2
chr6_+_117198400 0.15 ENST00000332958.2
RFX6
regulatory factor X, 6
chr3_+_122785895 0.15 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr6_+_151561085 0.14 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr19_+_18668616 0.14 ENST00000600372.1
KXD1
KxDL motif containing 1
chr14_-_73997901 0.14 ENST00000557603.1
ENST00000556455.1
HEATR4
HEAT repeat containing 4
chr8_+_77318769 0.14 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr13_-_103426112 0.14 ENST00000376032.4
ENST00000376029.3
TEX30
testis expressed 30
chr1_+_40810516 0.14 ENST00000435168.2
SMAP2
small ArfGAP2
chr10_+_81462983 0.14 ENST00000448135.1
ENST00000429828.1
ENST00000372321.1
NUTM2B
NUT family member 2B
chr1_+_33546714 0.13 ENST00000294517.6
ENST00000358680.3
ENST00000373443.3
ENST00000398167.1
ADC
arginine decarboxylase
chr11_-_8857248 0.13 ENST00000534248.1
ENST00000530959.1
ENST00000531578.1
ENST00000533225.1
ST5
suppression of tumorigenicity 5
chr2_+_24272543 0.13 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr2_-_211342292 0.13 ENST00000448951.1
LANCL1
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr3_+_23851928 0.13 ENST00000467766.1
ENST00000424381.1
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr12_-_13248598 0.13 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr9_-_111882195 0.13 ENST00000374586.3
TMEM245
transmembrane protein 245
chr6_-_53481847 0.13 ENST00000503985.1
RP1-27K12.2
RP1-27K12.2
chr14_+_65381079 0.13 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
CHURC1
FNTB
CHURC1-FNTB
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr14_-_20801427 0.12 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr6_-_51952367 0.12 ENST00000340994.4
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr2_+_172309634 0.12 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr2_-_171571077 0.12 ENST00000409786.1
AC007405.2
long intergenic non-protein coding RNA 1124
chr12_+_128399917 0.12 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr3_-_187009798 0.12 ENST00000337774.5
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr8_+_32579341 0.12 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr3_+_173116225 0.12 ENST00000457714.1
NLGN1
neuroligin 1
chr4_-_168155169 0.12 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr6_-_51952418 0.12 ENST00000371117.3
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr17_-_73663245 0.12 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr9_+_130159409 0.12 ENST00000373371.3
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr21_+_44073860 0.11 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
PDE9A
phosphodiesterase 9A
chr1_+_144151520 0.11 ENST00000369372.4
NBPF8
neuroblastoma breakpoint family, member 8
chr2_-_130031335 0.11 ENST00000375987.3
AC079586.1
AC079586.1
chr7_-_20256965 0.11 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr3_+_16216137 0.11 ENST00000339732.5
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr7_-_87856280 0.11 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr20_+_3776371 0.11 ENST00000245960.5
CDC25B
cell division cycle 25B
chr4_-_39034542 0.11 ENST00000344606.6
TMEM156
transmembrane protein 156
chrX_-_153979315 0.11 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GAB3
GRB2-associated binding protein 3
chr14_+_92789498 0.11 ENST00000531433.1
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_-_112013071 0.11 ENST00000487372.1
ENST00000486574.1
ENST00000305815.5
SLC9C1
solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
chr1_-_217804377 0.11 ENST00000366935.3
ENST00000366934.3
GPATCH2
G patch domain containing 2
chr13_-_103426081 0.11 ENST00000376022.1
ENST00000376021.4
TEX30
testis expressed 30
chr2_+_109237717 0.10 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_51340469 0.10 ENST00000326856.4
KLK15
kallikrein-related peptidase 15
chr10_-_95242044 0.10 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr11_+_105480793 0.10 ENST00000282499.5
ENST00000393127.2
ENST00000527669.1
GRIA4
glutamate receptor, ionotropic, AMPA 4
chr1_-_21377447 0.10 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr17_+_48823896 0.10 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr2_-_111334678 0.10 ENST00000329516.3
ENST00000330331.5
ENST00000446930.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr1_+_70820451 0.10 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3
HERV-H LTR-associating 3
chr14_+_64565442 0.10 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chr9_-_116102530 0.09 ENST00000374195.3
ENST00000341761.4
WDR31
WD repeat domain 31
chr19_+_18668572 0.09 ENST00000540691.1
ENST00000539106.1
ENST00000222307.4
KXD1
KxDL motif containing 1
chr19_+_12175504 0.09 ENST00000439326.3
ZNF844
zinc finger protein 844
chr3_+_179280668 0.09 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chr11_-_118972575 0.09 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr19_-_44384291 0.09 ENST00000324394.6
ZNF404
zinc finger protein 404
chr3_+_101818088 0.09 ENST00000491959.1
ZPLD1
zona pellucida-like domain containing 1
chr2_-_20251744 0.09 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr2_+_27071045 0.09 ENST00000401478.1
DPYSL5
dihydropyrimidinase-like 5
chr21_+_44073916 0.09 ENST00000349112.3
ENST00000398224.3
PDE9A
phosphodiesterase 9A
chr19_-_36001113 0.09 ENST00000434389.1
DMKN
dermokine
chr14_-_59950724 0.09 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr3_+_186560462 0.09 ENST00000412955.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr14_+_32798462 0.09 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr18_+_76829385 0.08 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr8_-_93978346 0.08 ENST00000523580.1
TRIQK
triple QxxK/R motif containing
chr15_+_55700741 0.08 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr15_-_40074996 0.08 ENST00000350221.3
FSIP1
fibrous sheath interacting protein 1
chr15_-_50558223 0.08 ENST00000267845.3
HDC
histidine decarboxylase
chr17_-_76824975 0.08 ENST00000586066.2
USP36
ubiquitin specific peptidase 36
chr5_+_140227048 0.08 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr2_+_234826016 0.08 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr6_-_106773491 0.08 ENST00000360666.4
ATG5
autophagy related 5
chr5_+_154393260 0.08 ENST00000435029.4
KIF4B
kinesin family member 4B
chr7_-_87856303 0.08 ENST00000394641.3
SRI
sorcin
chr7_+_2393714 0.08 ENST00000431643.1
EIF3B
eukaryotic translation initiation factor 3, subunit B
chr18_+_10526008 0.08 ENST00000542979.1
ENST00000322897.6
NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr2_+_27071292 0.08 ENST00000431402.1
ENST00000434719.1
DPYSL5
dihydropyrimidinase-like 5
chr10_-_27529486 0.08 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr14_+_31091511 0.08 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
SCFD1
sec1 family domain containing 1
chr14_+_55595960 0.07 ENST00000554715.1
LGALS3
lectin, galactoside-binding, soluble, 3
chr14_+_50291993 0.07 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr8_-_93978333 0.07 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chr12_+_125811162 0.07 ENST00000299308.3
TMEM132B
transmembrane protein 132B
chr6_-_46138676 0.07 ENST00000371383.2
ENST00000230565.3
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr1_-_205290865 0.07 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr1_+_196946664 0.07 ENST00000367414.5
CFHR5
complement factor H-related 5
chr3_+_186560476 0.07 ENST00000320741.2
ENST00000444204.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr10_-_126849588 0.07 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr7_+_39125365 0.07 ENST00000559001.1
ENST00000464276.2
POU6F2
POU class 6 homeobox 2
chr2_+_108994633 0.07 ENST00000409309.3
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr10_-_115613828 0.07 ENST00000361384.2
DCLRE1A
DNA cross-link repair 1A
chr5_+_167913450 0.06 ENST00000231572.3
ENST00000538719.1
RARS
arginyl-tRNA synthetase
chr1_+_196946680 0.06 ENST00000256785.4
CFHR5
complement factor H-related 5
chr10_-_22292613 0.06 ENST00000376980.3
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr14_+_73706308 0.06 ENST00000554301.1
ENST00000555445.1
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr6_-_116833500 0.06 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr2_-_169104651 0.06 ENST00000355999.4
STK39
serine threonine kinase 39
chr3_+_156799587 0.06 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr19_-_14889349 0.06 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.8 GO:0052362 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.2 0.5 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.4 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.1 0.8 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.3 GO:0044417 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.2 GO:2000532 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 1.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.2 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 1.3 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.0 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.3 GO:0045141 meiotic telomere clustering(GO:0045141)
0.0 0.2 GO:0035562 protein desumoylation(GO:0016926) negative regulation of chromatin binding(GO:0035562)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.7 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.5 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.2 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.7 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0019863 IgE binding(GO:0019863)
0.1 0.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.0 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.4 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening