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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HMX1

Z-value: 1.58

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Transcription factors associated with HMX1

Gene Symbol Gene ID Gene Info
ENSG00000215612.5 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX1hg19_v2_chr4_-_8873531_8873543-0.841.6e-01Click!

Activity profile of HMX1 motif

Sorted Z-values of HMX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_826136 1.05 ENST00000528315.1
ENST00000533803.1
EF-hand calcium binding domain 4A
chr22_-_29196030 1.05 ENST00000405219.3
X-box binding protein 1
chr3_-_49066811 0.96 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr22_-_29196511 0.93 ENST00000344347.5
X-box binding protein 1
chr22_-_29196546 0.93 ENST00000403532.3
ENST00000216037.6
X-box binding protein 1
chr16_-_70712229 0.89 ENST00000562883.2
metastasis suppressor 1-like
chrX_+_70443050 0.87 ENST00000361726.6
gap junction protein, beta 1, 32kDa
chr7_-_16844611 0.75 ENST00000401412.1
ENST00000419304.2
anterior gradient 2
chr16_+_83986827 0.75 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chr17_-_74533734 0.75 ENST00000589342.1
cytoglobin
chr5_-_81046841 0.70 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
single-stranded DNA binding protein 2
chr22_-_39268308 0.65 ENST00000407418.3
chromobox homolog 6
chr19_+_41305612 0.65 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
egl-9 family hypoxia-inducible factor 2
chr3_+_50316458 0.65 ENST00000316436.3
leucine-rich single-pass membrane protein 2
chr12_-_15374343 0.63 ENST00000256953.2
ENST00000546331.1
RAS-like, estrogen-regulated, growth inhibitor
chr2_-_27341966 0.61 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
cell growth regulator with EF-hand domain 1
chr9_-_139948487 0.59 ENST00000355097.2
ectonucleoside triphosphate diphosphohydrolase 2
chr19_-_10697895 0.59 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
adaptor-related protein complex 1, mu 2 subunit
chr12_+_53399942 0.57 ENST00000262056.9
eukaryotic translation initiation factor 4B
chr22_-_18923655 0.56 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
proline dehydrogenase (oxidase) 1
chr8_+_98881268 0.55 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
matrilin 2
chr8_+_38854418 0.54 ENST00000481513.1
ENST00000487273.2
ADAM metallopeptidase domain 9
chr4_-_2420357 0.53 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
zinc finger, FYVE domain containing 28
chr19_+_496454 0.52 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
mucosal vascular addressin cell adhesion molecule 1
chr7_-_105332084 0.52 ENST00000472195.1
ataxin 7-like 1
chr2_+_27346666 0.52 ENST00000316470.4
ENST00000416071.1
abhydrolase domain containing 1
chrX_+_131157322 0.51 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chr19_-_10687948 0.51 ENST00000592285.1
adaptor-related protein complex 1, mu 2 subunit
chr2_-_27341765 0.50 ENST00000405600.1
cell growth regulator with EF-hand domain 1
chr9_-_98189055 0.50 ENST00000433644.2
RP11-435O5.2
chr1_-_26232522 0.50 ENST00000399728.1
stathmin 1
chrX_+_69509927 0.50 ENST00000374403.3
kinesin family member 4A
chr21_-_40685536 0.50 ENST00000341322.4
bromodomain and WD repeat domain containing 1
chr12_+_100867486 0.49 ENST00000548884.1
nuclear receptor subfamily 1, group H, member 4
chr16_+_3062457 0.49 ENST00000445369.2
claudin 9
chr3_-_142166846 0.49 ENST00000463916.1
ENST00000544157.1
5'-3' exoribonuclease 1
chr2_-_129076151 0.48 ENST00000259241.6
heparan sulfate 6-O-sulfotransferase 1
chr15_+_40763150 0.47 ENST00000306243.5
ENST00000559991.1
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr12_-_49259643 0.45 ENST00000309739.5
Rho family GTPase 1
chr1_-_109940550 0.45 ENST00000256637.6
sortilin 1
chr17_-_41132010 0.45 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1 readthrough
chrX_-_107019181 0.44 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22 domain family, member 3
chr19_-_46526304 0.44 ENST00000008938.4
peptidoglycan recognition protein 1
chr17_-_42298201 0.44 ENST00000527034.1
upstream binding transcription factor, RNA polymerase I
chr17_-_62097927 0.44 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
intercellular adhesion molecule 2
chr6_-_31550192 0.43 ENST00000429299.2
ENST00000446745.2
lymphotoxin beta (TNF superfamily, member 3)
chr17_-_42298331 0.42 ENST00000343638.5
upstream binding transcription factor, RNA polymerase I
chr14_+_56585048 0.41 ENST00000267460.4
pellino E3 ubiquitin protein ligase family member 2
chr20_-_62601218 0.41 ENST00000369888.1
zinc finger protein 512B
chr22_-_39268192 0.40 ENST00000216083.6
chromobox homolog 6
chr16_+_88872176 0.40 ENST00000569140.1
chromatin licensing and DNA replication factor 1
chr6_+_44095263 0.40 ENST00000532634.1
transmembrane protein 63B
chr1_+_95583479 0.40 ENST00000455656.1
ENST00000604534.1
transmembrane protein 56
TMEM56-RWDD3 readthrough
chr17_+_79213039 0.40 ENST00000431388.2
chromosome 17 open reading frame 89
chr3_-_67705006 0.40 ENST00000492795.1
ENST00000493112.1
ENST00000307227.5
succinate-CoA ligase, GDP-forming, beta subunit
chr11_+_118478313 0.39 ENST00000356063.5
pleckstrin homology-like domain, family B, member 1
chr16_+_28996416 0.39 ENST00000395456.2
ENST00000454369.2
linker for activation of T cells
chr5_+_141016969 0.38 ENST00000518856.1
RELT-like 2
chr13_+_35516390 0.38 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
neurobeachin
chr9_+_116263639 0.37 ENST00000343817.5
regulator of G-protein signaling 3
chr17_-_47755436 0.37 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
speckle-type POZ protein
chr12_+_100867733 0.37 ENST00000546380.1
nuclear receptor subfamily 1, group H, member 4
chr12_-_7077125 0.37 ENST00000545555.2
prohibitin 2
chr1_-_26232951 0.37 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr1_-_110052302 0.37 ENST00000369864.4
ENST00000369862.1
adhesion molecule with Ig-like domain 1
chr4_+_1795508 0.36 ENST00000260795.2
ENST00000352904.1
fibroblast growth factor receptor 3
chr19_+_5904866 0.36 ENST00000339485.3
vimentin-type intermediate filament associated coiled-coil protein
chr1_-_197744322 0.36 ENST00000235453.4
DENN/MADD domain containing 1B
chr9_+_116263778 0.35 ENST00000394646.3
regulator of G-protein signaling 3
chr12_+_53440753 0.34 ENST00000379902.3
tensin like C1 domain containing phosphatase (tensin 2)
chr19_+_41305330 0.34 ENST00000593972.1
egl-9 family hypoxia-inducible factor 2
chr13_-_76111945 0.34 ENST00000355801.4
ENST00000406936.3
COMM domain containing 6
chr19_+_41305740 0.34 ENST00000596517.1
egl-9 family hypoxia-inducible factor 2
chr19_+_41305406 0.34 ENST00000406058.2
ENST00000593726.1
egl-9 family hypoxia-inducible factor 2
chr22_-_38349552 0.34 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
chromosome 22 open reading frame 23
chr13_+_42031679 0.34 ENST00000379359.3
regulator of cell cycle
chr9_-_130617029 0.34 ENST00000373203.4
endoglin
chr19_+_41313017 0.33 ENST00000595621.1
ENST00000595051.1
egl-9 family hypoxia-inducible factor 2
chr13_+_76123883 0.33 ENST00000377595.3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr19_+_6464243 0.33 ENST00000600229.1
ENST00000356762.3
crumbs homolog 3 (Drosophila)
chr10_-_82049424 0.33 ENST00000372213.3
methionine adenosyltransferase I, alpha
chr12_+_7060414 0.33 ENST00000538715.1
protein tyrosine phosphatase, non-receptor type 6
chr22_-_24093267 0.32 ENST00000341976.3
zinc finger protein 70
chrX_-_20284958 0.32 ENST00000379565.3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr19_+_41305627 0.32 ENST00000593525.1
egl-9 family hypoxia-inducible factor 2
chr19_-_13068012 0.32 ENST00000316939.1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr3_+_20081515 0.32 ENST00000263754.4
K(lysine) acetyltransferase 2B
chr8_+_145438870 0.32 ENST00000527931.1
family with sequence similarity 203, member B
chr12_+_16035307 0.31 ENST00000538352.1
ENST00000025399.6
ENST00000419869.2
serine/threonine kinase receptor associated protein
chr11_+_105948216 0.31 ENST00000278618.4
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr9_-_130616915 0.31 ENST00000344849.3
endoglin
chrX_+_131157290 0.31 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr5_+_95998714 0.31 ENST00000506811.1
ENST00000514055.1
calpastatin
chr12_+_53400176 0.31 ENST00000551002.1
ENST00000420463.3
ENST00000416762.3
ENST00000549481.1
ENST00000552490.1
eukaryotic translation initiation factor 4B
chr1_-_6052463 0.31 ENST00000378156.4
nephronophthisis 4
chr19_-_10687907 0.31 ENST00000589348.1
adaptor-related protein complex 1, mu 2 subunit
chr5_+_176784837 0.30 ENST00000408923.3
regulator of G-protein signaling 14
chr14_+_31343747 0.30 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
cochlin
chr1_+_226411319 0.30 ENST00000542034.1
ENST00000366810.5
Mix paired-like homeobox
chr8_+_120428546 0.30 ENST00000259526.3
nephroblastoma overexpressed
chr7_-_37488834 0.30 ENST00000310758.4
engulfment and cell motility 1
chr17_+_79679299 0.29 ENST00000331531.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr12_-_49318715 0.29 ENST00000444214.2
FK506 binding protein 11, 19 kDa
chrX_-_153285251 0.29 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr3_-_107941209 0.28 ENST00000492106.1
intraflagellar transport 57 homolog (Chlamydomonas)
chr17_-_8534031 0.28 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
myosin, heavy chain 10, non-muscle
chr11_-_62607036 0.28 ENST00000311713.7
ENST00000278856.4
WD repeat domain 74
chr19_-_10687983 0.28 ENST00000587069.1
adaptor-related protein complex 1, mu 2 subunit
chr7_-_752577 0.28 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr19_+_41305085 0.27 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr1_+_38512799 0.26 ENST00000432922.1
ENST00000428151.1
RP5-884C9.2
chr5_+_31193847 0.26 ENST00000514738.1
ENST00000265071.2
cadherin 6, type 2, K-cadherin (fetal kidney)
chr1_-_197744390 0.26 ENST00000367396.3
DENN/MADD domain containing 1B
chr6_-_8102279 0.25 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr9_-_74525847 0.25 ENST00000377041.2
abhydrolase domain containing 17B
chr6_-_128841503 0.25 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
protein tyrosine phosphatase, receptor type, K
chr1_-_207095324 0.25 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr12_+_4430371 0.24 ENST00000179259.4
chromosome 12 open reading frame 5
chr4_-_144826682 0.24 ENST00000358615.4
ENST00000437468.2
glycophorin E (MNS blood group)
chr5_+_156693091 0.24 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
cytoplasmic FMR1 interacting protein 2
chr12_+_7060508 0.24 ENST00000541698.1
ENST00000542462.1
protein tyrosine phosphatase, non-receptor type 6
chr22_+_38349724 0.24 ENST00000470701.1
polymerase (RNA) II (DNA directed) polypeptide F
chr17_-_55038375 0.24 ENST00000240316.4
coilin
chr17_+_79679369 0.24 ENST00000350690.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr15_-_75748143 0.23 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3 transcription regulator family member A
chr13_+_37574678 0.23 ENST00000389704.3
exosome component 8
chr11_-_76155700 0.23 ENST00000572035.1
RP11-111M22.3
chr9_-_136024721 0.23 ENST00000393160.3
ral guanine nucleotide dissociation stimulator
chr12_+_125478241 0.23 ENST00000341446.8
BRI3 binding protein
chr22_+_47070490 0.23 ENST00000408031.1
GRAM domain containing 4
chr3_+_151986709 0.23 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
muscleblind-like splicing regulator 1
chr10_-_99531709 0.23 ENST00000266066.3
secreted frizzled-related protein 5
chr14_+_90422239 0.22 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
tyrosyl-DNA phosphodiesterase 1
chr3_-_52864680 0.22 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr16_-_58034357 0.22 ENST00000562909.1
zinc finger protein 319
chr5_+_139027877 0.22 ENST00000302517.3
CXXC finger protein 5
chr5_+_148206156 0.21 ENST00000305988.4
adrenoceptor beta 2, surface
chr1_-_198906528 0.21 ENST00000432296.1
MIR181A1 host gene (non-protein coding)
chr1_+_53480598 0.20 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chr17_+_9548845 0.20 ENST00000570475.1
ENST00000285199.7
ubiquitin specific peptidase 43
chr8_-_26371608 0.20 ENST00000522362.2
paraneoplastic Ma antigen 2
chr5_+_95998746 0.20 ENST00000508608.1
calpastatin
chr22_-_38480100 0.20 ENST00000427592.1
solute carrier family 16 (monocarboxylate transporter), member 8
chr6_-_136871957 0.20 ENST00000354570.3
microtubule-associated protein 7
chr1_+_110162448 0.19 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
adenosine monophosphate deaminase 2
chr1_+_178995021 0.19 ENST00000263733.4
family with sequence similarity 20, member B
chr18_+_11981547 0.19 ENST00000588927.1
inositol(myo)-1(or 4)-monophosphatase 2
chr9_+_137967366 0.19 ENST00000252854.4
olfactomedin 1
chr1_+_203444887 0.19 ENST00000343110.2
proline/arginine-rich end leucine-rich repeat protein
chr1_-_53387352 0.19 ENST00000541281.1
enoyl CoA hydratase domain containing 2
chr17_-_7165662 0.19 ENST00000571881.2
ENST00000360325.7
claudin 7
chr5_+_156693159 0.19 ENST00000347377.6
cytoplasmic FMR1 interacting protein 2
chr10_+_126150369 0.19 ENST00000392757.4
ENST00000368842.5
ENST00000368839.1
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chrX_-_153285395 0.19 ENST00000369980.3
interleukin-1 receptor-associated kinase 1
chr11_+_66624527 0.19 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr3_-_125775629 0.18 ENST00000383598.2
solute carrier family 41, member 3
chr2_-_219925189 0.18 ENST00000295731.6
indian hedgehog
chr1_+_110163682 0.18 ENST00000358729.4
adenosine monophosphate deaminase 2
chr17_-_1619491 0.18 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22 host gene (non-protein coding)
chr2_-_167232484 0.18 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
sodium channel, voltage-gated, type IX, alpha subunit
chr19_+_36346734 0.18 ENST00000586102.3
kin of IRRE like 2 (Drosophila)
chr17_-_41132410 0.18 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr14_-_21905424 0.18 ENST00000553622.1
chromodomain helicase DNA binding protein 8
chr15_-_79103757 0.18 ENST00000388820.4
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr1_+_110163202 0.18 ENST00000531203.1
ENST00000256578.3
adenosine monophosphate deaminase 2
chr11_-_559377 0.17 ENST00000486629.1
chromosome 11 open reading frame 35
chr14_+_31343951 0.17 ENST00000556908.1
ENST00000555881.1
ENST00000460581.2
cochlin
chr6_-_8102714 0.17 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr1_-_24194771 0.17 ENST00000374479.3
fucosidase, alpha-L- 1, tissue
chr7_-_128171123 0.17 ENST00000608477.1
RP11-212P7.2
chr20_+_2633269 0.17 ENST00000445139.1
NOP56 ribonucleoprotein
chr4_-_140005341 0.17 ENST00000379549.2
ENST00000512627.1
E74-like factor 2 (ets domain transcription factor)
chr12_+_56401268 0.17 ENST00000262032.5
IKAROS family zinc finger 4 (Eos)
chr7_+_130131907 0.16 ENST00000223215.4
ENST00000437945.1
mesoderm specific transcript
chr20_+_47538357 0.16 ENST00000371917.4
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr5_-_37371163 0.16 ENST00000513532.1
nucleoporin 155kDa
chr15_-_90198659 0.16 ENST00000394412.3
kinesin family member 7
chr17_+_19912640 0.16 ENST00000395527.4
ENST00000583482.2
ENST00000583528.1
ENST00000583463.1
sperm antigen with calponin homology and coiled-coil domains 1
chr17_-_8534067 0.15 ENST00000360416.3
ENST00000269243.4
myosin, heavy chain 10, non-muscle
chr14_+_23775971 0.15 ENST00000250405.5
BCL2-like 2
chr4_-_71705027 0.15 ENST00000545193.1
G-rich RNA sequence binding factor 1
chr17_+_77751931 0.15 ENST00000310942.4
ENST00000269399.5
chromobox homolog 2
chr11_+_65819802 0.15 ENST00000528302.1
ENST00000322535.6
ENST00000524627.1
ENST00000533595.1
ENST00000530322.1
splicing factor 3b, subunit 2, 145kDa
chr3_-_192445289 0.15 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
fibroblast growth factor 12
chr8_-_67525473 0.14 ENST00000522677.3
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr1_-_51425772 0.14 ENST00000371778.4
Fas (TNFRSF6) associated factor 1
chr1_+_110163709 0.14 ENST00000369840.2
ENST00000527846.1
adenosine monophosphate deaminase 2
chr7_-_74267836 0.14 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
GTF2I repeat domain containing 2
chr19_-_1401486 0.14 ENST00000252288.2
ENST00000447102.3
guanidinoacetate N-methyltransferase
chr5_+_95998673 0.14 ENST00000514845.1
calpastatin
chrX_-_20284733 0.14 ENST00000438357.1
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr7_-_37488777 0.14 ENST00000445322.1
ENST00000448602.1
engulfment and cell motility 1
chr10_-_99258135 0.14 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr11_+_59522837 0.14 ENST00000437946.2
syntaxin 3
chr5_+_5140436 0.14 ENST00000511368.1
ENST00000274181.7
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr12_+_110152033 0.14 ENST00000538780.1
family with sequence similarity 222, member A
chr16_-_18937726 0.14 ENST00000389467.3
ENST00000446231.2
SMG1 phosphatidylinositol 3-kinase-related kinase
chr21_+_46875424 0.14 ENST00000359759.4
collagen, type XVIII, alpha 1
chr20_+_3451650 0.13 ENST00000262919.5
attractin
chr1_+_9648921 0.13 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
transmembrane protein 201

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:1903487 epithelial cell differentiation involved in salivary gland development(GO:0060690) epithelial cell maturation involved in salivary gland development(GO:0060691) regulation of plasma cell differentiation(GO:1900098) positive regulation of plasma cell differentiation(GO:1900100) regulation of lactation(GO:1903487) positive regulation of lactation(GO:1903489)
0.2 0.9 GO:1903314 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 0.9 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 0.6 GO:0001300 chronological cell aging(GO:0001300)
0.2 2.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 0.5 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.4 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826) regulation of cytolysis in other organism(GO:0051710)
0.1 1.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.9 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.8 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.7 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.6 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.6 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.3 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.7 GO:0032264 IMP salvage(GO:0032264)
0.1 0.9 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 0.2 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.2 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.4 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.4 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.4 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.4 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.9 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.6 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 1.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.4 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:1901166 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.5 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.5 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.1 GO:0061525 hindgut development(GO:0061525)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.6 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.4 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.4 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 1.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 0.9 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 0.9 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.2 1.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 0.7 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.2 0.5 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.2 0.5 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.2 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.9 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.6 GO:0005534 galactose binding(GO:0005534)
0.1 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.5 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.4 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.2 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 0.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.2 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0050544 icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 3.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 1.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation