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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HMBOX1

Z-value: 1.24

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Transcription factors associated with HMBOX1

Gene Symbol Gene ID Gene Info
HMBOX1
ENSG00000147421.13 homeobox containing 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMBOX1hg19_v2_chr8_+_28747884_287479380.623.8e-01Click!

Activity profile of HMBOX1 motif

Sorted Z-values of HMBOX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_57229155 0.83 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr10_+_115312766 0.79 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr22_-_37880543 0.75 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_-_95220775 0.69 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr17_+_26638667 0.66 ENST00000600595.1
AC061975.10
Uncharacterized protein
chr13_-_67802549 0.63 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr13_+_44596471 0.57 ENST00000592085.1
ENST00000591799.1
LINC00284
long intergenic non-protein coding RNA 284
chr6_-_107235331 0.56 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
RP1-60O19.1
chr12_-_51418549 0.56 ENST00000548150.1
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr1_+_109632425 0.56 ENST00000338272.8
TMEM167B
transmembrane protein 167B
chr1_-_86861660 0.53 ENST00000486215.1
ODF2L
outer dense fiber of sperm tails 2-like
chr8_+_27491572 0.50 ENST00000301904.3
SCARA3
scavenger receptor class A, member 3
chr2_-_14541060 0.49 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr14_+_56078695 0.48 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr3_-_149095652 0.46 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chrX_+_66764375 0.45 ENST00000374690.3
AR
androgen receptor
chr6_-_52628271 0.45 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr4_-_140477928 0.45 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr1_+_116654376 0.44 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr6_-_112408661 0.42 ENST00000368662.5
TUBE1
tubulin, epsilon 1
chr7_+_100728720 0.41 ENST00000306085.6
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr3_-_131756559 0.41 ENST00000505957.1
CPNE4
copine IV
chr5_+_92919043 0.40 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr10_+_112679301 0.39 ENST00000265277.5
ENST00000369452.4
SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr11_-_82681626 0.39 ENST00000534396.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr10_+_89419370 0.38 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr16_-_71610985 0.35 ENST00000355962.4
TAT
tyrosine aminotransferase
chr13_+_48611665 0.35 ENST00000258662.2
NUDT15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr5_-_133968459 0.34 ENST00000505758.1
ENST00000439578.1
ENST00000502286.1
SAR1B
SAR1 homolog B (S. cerevisiae)
chr12_+_94071341 0.33 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr16_-_30597000 0.33 ENST00000470110.1
ENST00000395216.2
ZNF785
zinc finger protein 785
chrX_-_20237059 0.32 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr2_-_38604398 0.32 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
ATL2
atlastin GTPase 2
chr11_+_17281900 0.31 ENST00000530527.1
NUCB2
nucleobindin 2
chr8_-_74659693 0.31 ENST00000518767.1
STAU2
staufen double-stranded RNA binding protein 2
chr3_-_151176497 0.31 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr8_+_107738240 0.30 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr4_-_152149033 0.30 ENST00000514152.1
SH3D19
SH3 domain containing 19
chrX_-_20236970 0.30 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_-_93257951 0.30 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
EVI5
ecotropic viral integration site 5
chr19_+_16178317 0.30 ENST00000344824.6
ENST00000538887.1
TPM4
tropomyosin 4
chr7_-_17598506 0.29 ENST00000451792.1
AC017060.1
AC017060.1
chr20_+_42187682 0.28 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chr18_-_32870148 0.28 ENST00000589178.1
ENST00000333206.5
ENST00000592278.1
ENST00000592211.1
ENST00000420878.3
ENST00000383091.2
ENST00000586922.2
ZSCAN30
RP11-158H5.7
zinc finger and SCAN domain containing 30
RP11-158H5.7
chr14_+_31028348 0.27 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr1_+_100436065 0.27 ENST00000370153.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr22_-_36761081 0.27 ENST00000456729.1
ENST00000401701.1
MYH9
myosin, heavy chain 9, non-muscle
chr5_+_70751442 0.27 ENST00000358731.4
ENST00000380675.2
BDP1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr6_-_86303833 0.26 ENST00000505648.1
SNX14
sorting nexin 14
chr2_+_128458514 0.25 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr4_+_25915896 0.25 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr12_-_25348007 0.25 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr4_-_110723134 0.25 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr1_-_150669500 0.24 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr2_-_86948245 0.24 ENST00000439940.2
ENST00000604011.1
CHMP3
RNF103-CHMP3
charged multivesicular body protein 3
RNF103-CHMP3 readthrough
chr5_+_131705438 0.24 ENST00000245407.3
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr7_-_28220354 0.24 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr1_+_84609944 0.24 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_-_137667526 0.24 ENST00000503022.1
CDC25C
cell division cycle 25C
chr2_-_3521518 0.24 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr15_+_69857515 0.24 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr8_-_95449155 0.23 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr17_+_42925270 0.23 ENST00000253410.2
ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr16_-_71842941 0.23 ENST00000423132.2
ENST00000433195.2
ENST00000569748.1
ENST00000570017.1
AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr6_-_8102714 0.23 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr7_+_134576317 0.23 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr11_+_100862811 0.22 ENST00000303130.2
TMEM133
transmembrane protein 133
chr1_+_219347203 0.22 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr1_-_204654826 0.21 ENST00000367177.3
LRRN2
leucine rich repeat neuronal 2
chr3_-_69101461 0.21 ENST00000543976.1
TMF1
TATA element modulatory factor 1
chr4_-_110723194 0.21 ENST00000394635.3
CFI
complement factor I
chr1_-_86861936 0.21 ENST00000394733.2
ENST00000359242.3
ENST00000294678.2
ENST00000479890.1
ENST00000317336.7
ENST00000370567.1
ENST00000394731.1
ENST00000478286.2
ENST00000370566.3
ODF2L
outer dense fiber of sperm tails 2-like
chr20_+_42187608 0.21 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr3_+_159481791 0.21 ENST00000460298.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr2_+_61293021 0.21 ENST00000402291.1
KIAA1841
KIAA1841
chr1_+_153940741 0.21 ENST00000431292.1
CREB3L4
cAMP responsive element binding protein 3-like 4
chr8_+_67976593 0.21 ENST00000262210.5
ENST00000412460.1
CSPP1
centrosome and spindle pole associated protein 1
chr6_-_165989936 0.21 ENST00000354448.4
PDE10A
phosphodiesterase 10A
chr9_-_104145795 0.20 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr4_+_77941685 0.20 ENST00000506731.1
SEPT11
septin 11
chr6_-_107235287 0.20 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
RP1-60O19.1
chr12_+_28343353 0.20 ENST00000539107.1
CCDC91
coiled-coil domain containing 91
chr7_+_149416439 0.19 ENST00000497895.1
KRBA1
KRAB-A domain containing 1
chr7_-_102985288 0.19 ENST00000379263.3
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr17_-_38083092 0.19 ENST00000394169.1
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr17_+_48172639 0.19 ENST00000503176.1
ENST00000503614.1
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr1_-_9970227 0.19 ENST00000377263.1
CTNNBIP1
catenin, beta interacting protein 1
chr8_-_67977178 0.19 ENST00000517736.1
COPS5
COP9 signalosome subunit 5
chr14_+_75536335 0.19 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr2_+_162087577 0.19 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chrX_+_114874727 0.18 ENST00000543070.1
PLS3
plastin 3
chr16_+_89696692 0.18 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chr17_-_56494882 0.18 ENST00000584437.1
RNF43
ring finger protein 43
chrX_-_74376108 0.18 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr17_+_44701402 0.18 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr12_+_28343365 0.18 ENST00000545336.1
CCDC91
coiled-coil domain containing 91
chr12_+_51633061 0.18 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr14_+_75536280 0.18 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr1_+_45212051 0.18 ENST00000372222.3
KIF2C
kinesin family member 2C
chrX_+_70503037 0.18 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr12_-_33049690 0.17 ENST00000070846.6
ENST00000340811.4
PKP2
plakophilin 2
chr1_-_21113105 0.17 ENST00000375000.1
ENST00000419490.1
ENST00000414993.1
ENST00000443615.1
ENST00000312239.5
HP1BP3
heterochromatin protein 1, binding protein 3
chr5_+_173316341 0.17 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr3_+_69928256 0.17 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr1_+_219347186 0.17 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr17_-_56494908 0.17 ENST00000577716.1
RNF43
ring finger protein 43
chr8_+_120885949 0.17 ENST00000523492.1
ENST00000286234.5
DEPTOR
DEP domain containing MTOR-interacting protein
chr14_-_50999307 0.17 ENST00000013125.4
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr2_+_109335929 0.17 ENST00000283195.6
RANBP2
RAN binding protein 2
chr3_-_121448791 0.17 ENST00000489400.1
GOLGB1
golgin B1
chr14_-_65289812 0.16 ENST00000389720.3
ENST00000389721.5
ENST00000389722.3
SPTB
spectrin, beta, erythrocytic
chr14_+_45431379 0.16 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
FAM179B
family with sequence similarity 179, member B
chr17_+_15602891 0.16 ENST00000421016.1
ENST00000593105.1
ENST00000580259.1
ENST00000583566.1
ENST00000472486.1
ENST00000395894.2
ENST00000581529.1
ENST00000579694.1
ENST00000580393.1
ENST00000585194.1
ENST00000583031.1
ENST00000464847.2
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr2_-_62081148 0.16 ENST00000404929.1
FAM161A
family with sequence similarity 161, member A
chr3_-_69101413 0.16 ENST00000398559.2
TMF1
TATA element modulatory factor 1
chr1_+_153940713 0.15 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
CREB3L4
cAMP responsive element binding protein 3-like 4
chr6_+_30585486 0.15 ENST00000259873.4
ENST00000506373.2
MRPS18B
mitochondrial ribosomal protein S18B
chr19_+_4769117 0.15 ENST00000540211.1
ENST00000317292.3
ENST00000586721.1
ENST00000592709.1
ENST00000588711.1
ENST00000589639.1
ENST00000591008.1
ENST00000592663.1
ENST00000588758.1
MIR7-3HG
MIR7-3 host gene (non-protein coding)
chr3_-_49142504 0.15 ENST00000306125.6
ENST00000420147.2
QARS
glutaminyl-tRNA synthetase
chr5_-_137667459 0.15 ENST00000415130.2
ENST00000356505.3
ENST00000357274.3
ENST00000348983.3
ENST00000323760.6
CDC25C
cell division cycle 25C
chr6_+_134758827 0.15 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr19_-_35992780 0.15 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr3_-_141747459 0.15 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr9_+_33290491 0.14 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
NFX1
nuclear transcription factor, X-box binding 1
chr1_+_24286287 0.14 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr7_+_134576151 0.14 ENST00000393118.2
CALD1
caldesmon 1
chr14_-_50999373 0.14 ENST00000554273.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr3_+_101504200 0.14 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr6_-_26199471 0.14 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr14_+_90422239 0.14 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
TDP1
tyrosyl-DNA phosphodiesterase 1
chr6_+_46097711 0.13 ENST00000321037.4
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr6_+_26199737 0.13 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr3_+_52444651 0.12 ENST00000327906.3
PHF7
PHD finger protein 7
chr2_-_99952769 0.12 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
TXNDC9
thioredoxin domain containing 9
chr1_+_196743943 0.12 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr11_+_10772534 0.12 ENST00000361367.2
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr1_+_87595433 0.12 ENST00000469312.2
ENST00000490006.2
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr10_-_115904361 0.12 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr2_-_133429091 0.12 ENST00000345008.6
LYPD1
LY6/PLAUR domain containing 1
chr2_-_220110111 0.11 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L
galactosidase, beta 1-like
chr21_+_45725050 0.11 ENST00000403390.1
PFKL
phosphofructokinase, liver
chr3_+_37035289 0.11 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
MLH1
mutL homolog 1
chr1_+_117602925 0.11 ENST00000369466.4
TTF2
transcription termination factor, RNA polymerase II
chr7_+_132937820 0.11 ENST00000393161.2
ENST00000253861.4
EXOC4
exocyst complex component 4
chr10_-_94257512 0.11 ENST00000371581.5
IDE
insulin-degrading enzyme
chr20_+_43211149 0.11 ENST00000372886.1
PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr8_-_101734170 0.11 ENST00000522387.1
ENST00000518196.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr8_-_28347737 0.11 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
FBXO16
F-box protein 16
chr1_-_32384693 0.11 ENST00000602683.1
ENST00000470404.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr1_+_207943667 0.10 ENST00000462968.2
CD46
CD46 molecule, complement regulatory protein
chr10_-_14574705 0.10 ENST00000489100.1
FAM107B
family with sequence similarity 107, member B
chr11_+_13690200 0.10 ENST00000354817.3
FAR1
fatty acyl CoA reductase 1
chr6_+_96969672 0.10 ENST00000369278.4
UFL1
UFM1-specific ligase 1
chr19_-_7553852 0.10 ENST00000593547.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr12_+_117013656 0.09 ENST00000556529.1
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr16_-_71843047 0.09 ENST00000299980.4
ENST00000393512.3
AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr1_-_160549235 0.09 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr15_+_79603479 0.09 ENST00000424155.2
ENST00000536821.1
TMED3
transmembrane emp24 protein transport domain containing 3
chr22_-_37172111 0.08 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr1_+_240408560 0.08 ENST00000441342.1
ENST00000545751.1
FMN2
formin 2
chr4_-_47465666 0.08 ENST00000381571.4
COMMD8
COMM domain containing 8
chr2_+_227771404 0.08 ENST00000409053.1
RHBDD1
rhomboid domain containing 1
chr2_+_220110177 0.08 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
STK16
serine/threonine kinase 16
chr10_+_124913793 0.08 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3
BUB3 mitotic checkpoint protein
chr14_-_21566731 0.08 ENST00000360947.3
ZNF219
zinc finger protein 219
chr10_+_75936444 0.08 ENST00000372734.3
ENST00000541550.1
ADK
adenosine kinase
chr2_-_62081254 0.08 ENST00000405894.3
FAM161A
family with sequence similarity 161, member A
chr14_+_31028329 0.08 ENST00000206595.6
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr17_-_74049720 0.08 ENST00000602720.1
SRP68
signal recognition particle 68kDa
chr11_+_19798964 0.08 ENST00000527559.2
NAV2
neuron navigator 2
chr7_+_102191679 0.08 ENST00000507918.1
ENST00000432940.1
SPDYE2
speedy/RINGO cell cycle regulator family member E2
chr1_+_81001398 0.07 ENST00000418041.1
ENST00000443104.1
RP5-887A10.1
RP5-887A10.1
chr14_+_21458127 0.07 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
METTL17
methyltransferase like 17
chr6_-_27114577 0.07 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr1_+_207226574 0.07 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr13_-_108870623 0.07 ENST00000405925.1
LIG4
ligase IV, DNA, ATP-dependent
chr4_-_114438763 0.07 ENST00000509594.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr7_+_102290772 0.07 ENST00000507450.1
SPDYE2B
speedy/RINGO cell cycle regulator family member E2B
chrX_+_109246285 0.07 ENST00000372073.1
ENST00000372068.2
ENST00000288381.4
TMEM164
transmembrane protein 164
chr1_-_27216729 0.07 ENST00000431781.2
ENST00000374135.4
GPN2
GPN-loop GTPase 2
chrX_+_70503526 0.07 ENST00000413858.1
ENST00000450092.1
NONO
non-POU domain containing, octamer-binding
chr6_+_112408768 0.07 ENST00000368656.2
ENST00000604268.1
FAM229B
family with sequence similarity 229, member B
chr17_-_56494713 0.07 ENST00000407977.2
RNF43
ring finger protein 43
chr17_-_62493131 0.07 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr12_-_122018859 0.07 ENST00000536437.1
ENST00000377071.4
ENST00000538046.2
KDM2B
lysine (K)-specific demethylase 2B
chr1_-_9970383 0.06 ENST00000400904.3
CTNNBIP1
catenin, beta interacting protein 1
chr2_+_24714729 0.06 ENST00000406961.1
ENST00000405141.1
NCOA1
nuclear receptor coactivator 1
chrX_+_37208521 0.06 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr7_+_135242652 0.06 ENST00000285968.6
ENST00000440390.2
NUP205
nucleoporin 205kDa
chr15_+_42131011 0.06 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr2_+_192543153 0.06 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr10_-_24911746 0.06 ENST00000320481.6
ARHGAP21
Rho GTPase activating protein 21
chr12_+_54674482 0.06 ENST00000547708.1
ENST00000340913.6
ENST00000551702.1
ENST00000330752.8
ENST00000547276.1
HNRNPA1
heterogeneous nuclear ribonucleoprotein A1
chr1_+_89246647 0.05 ENST00000544045.1
PKN2
protein kinase N2
chr12_+_56522001 0.05 ENST00000267113.4
ENST00000541590.1
ESYT1
extended synaptotagmin-like protein 1
chr3_-_45837959 0.05 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr3_-_42623805 0.05 ENST00000456515.1
SEC22C
SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
chrX_+_37208540 0.05 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
PRRG1
TM4SF2
proline rich Gla (G-carboxyglutamic acid) 1
Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr4_-_159080806 0.05 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr5_+_138629417 0.05 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3
matrin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of HMBOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.1 0.7 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.6 GO:0015692 lead ion transport(GO:0015692)
0.1 0.3 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.2 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.1 0.4 GO:2000843 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.3 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 0.4 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.2 GO:0043605 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.1 0.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.3 GO:0032796 uropod organization(GO:0032796)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.2 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.4 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0048496 adherens junction maintenance(GO:0034334) maintenance of organ identity(GO:0048496)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.5 GO:0009650 UV protection(GO:0009650)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.2 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0015886 heme transport(GO:0015886)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.4 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.4 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.3 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 0.6 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.3 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.2 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.4 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.3 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.2 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.2 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.0 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport