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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HLF_TEF

Z-value: 1.25

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Transcription factors associated with HLF_TEF

Gene Symbol Gene ID Gene Info
HLF
ENSG00000108924.9 HLF transcription factor, PAR bZIP family member
TEF
ENSG00000167074.10 TEF transcription factor, PAR bZIP family member

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HLFhg19_v2_chr17_+_53343577_533435881.003.4e-03Click!
TEFhg19_v2_chr22_+_41763274_417633370.927.7e-02Click!

Activity profile of HLF_TEF motif

Sorted Z-values of HLF_TEF motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_158390282 1.79 ENST00000264265.3
LXN
latexin
chr1_+_154377669 1.30 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr20_+_4666882 1.06 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr3_+_186330712 1.00 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr17_+_70036164 0.97 ENST00000602013.1
AC007461.1
Uncharacterized protein
chr1_+_7844312 0.95 ENST00000377541.1
PER3
period circadian clock 3
chr8_-_27469383 0.85 ENST00000519742.1
CLU
clusterin
chr1_-_226496772 0.81 ENST00000359525.2
ENST00000460719.1
LIN9
lin-9 homolog (C. elegans)
chr20_+_4667094 0.77 ENST00000424424.1
ENST00000457586.1
PRNP
prion protein
chr8_-_27468842 0.76 ENST00000523500.1
CLU
clusterin
chr1_+_212738676 0.76 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr16_-_53537105 0.75 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
AKTIP
AKT interacting protein
chr13_-_46626820 0.72 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chr14_+_75894391 0.69 ENST00000419727.2
JDP2
Jun dimerization protein 2
chr8_-_27468717 0.68 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr8_-_27469196 0.68 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr8_-_27468945 0.66 ENST00000405140.3
CLU
clusterin
chr5_+_95997918 0.60 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
CAST
calpastatin
chr1_+_229440129 0.57 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr16_-_54962415 0.56 ENST00000501177.3
ENST00000559598.2
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr6_-_86353510 0.55 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr13_-_46626847 0.53 ENST00000242848.4
ENST00000282007.3
ZC3H13
zinc finger CCCH-type containing 13
chr5_+_95998070 0.52 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
CAST
calpastatin
chr7_+_90032667 0.48 ENST00000496677.1
ENST00000287916.4
ENST00000535571.1
ENST00000394604.1
ENST00000394605.2
CLDN12
claudin 12
chr16_-_54962704 0.48 ENST00000502066.2
ENST00000560912.1
ENST00000558952.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr1_+_65613513 0.47 ENST00000395334.2
AK4
adenylate kinase 4
chr1_-_114429997 0.46 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr5_+_95997769 0.46 ENST00000338252.3
ENST00000508830.1
CAST
calpastatin
chr5_+_95997885 0.44 ENST00000511097.2
CAST
calpastatin
chr7_+_23145884 0.42 ENST00000409689.1
ENST00000410047.1
KLHL7
kelch-like family member 7
chr14_-_23284703 0.41 ENST00000555911.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr7_-_141401951 0.41 ENST00000536163.1
KIAA1147
KIAA1147
chr19_-_2042065 0.41 ENST00000591588.1
ENST00000591142.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr3_+_101504200 0.41 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr4_+_157997273 0.39 ENST00000541722.1
ENST00000512619.1
GLRB
glycine receptor, beta
chr18_+_32621324 0.37 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr5_+_172332220 0.37 ENST00000518247.1
ENST00000326654.2
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr14_-_23285069 0.37 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr10_+_94050913 0.37 ENST00000358935.2
MARCH5
membrane-associated ring finger (C3HC4) 5
chr2_+_183989157 0.36 ENST00000541912.1
NUP35
nucleoporin 35kDa
chr14_-_23285011 0.35 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr3_-_58200398 0.34 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
DNASE1L3
deoxyribonuclease I-like 3
chr9_+_71820057 0.34 ENST00000539225.1
TJP2
tight junction protein 2
chr1_+_196621156 0.33 ENST00000359637.2
CFH
complement factor H
chr17_-_19651598 0.33 ENST00000570414.1
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr18_+_3262954 0.33 ENST00000584539.1
MYL12B
myosin, light chain 12B, regulatory
chr13_-_45010939 0.33 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr8_+_19536083 0.32 ENST00000519803.1
RP11-1105O14.1
RP11-1105O14.1
chr2_-_167232484 0.31 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr9_+_71819927 0.30 ENST00000535702.1
TJP2
tight junction protein 2
chr9_-_123639445 0.30 ENST00000312189.6
PHF19
PHD finger protein 19
chr1_+_90308981 0.30 ENST00000527156.1
LRRC8D
leucine rich repeat containing 8 family, member D
chr18_-_55288973 0.30 ENST00000423481.2
ENST00000587194.1
ENST00000591599.1
ENST00000588661.1
NARS
asparaginyl-tRNA synthetase
chr8_+_107738240 0.30 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr9_-_34665983 0.29 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr9_-_123639304 0.27 ENST00000436309.1
PHF19
PHD finger protein 19
chr9_-_88356789 0.27 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
AGTPBP1
ATP/GTP binding protein 1
chr11_+_105948216 0.26 ENST00000278618.4
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr16_+_70680439 0.26 ENST00000288098.2
IL34
interleukin 34
chr4_-_153274078 0.26 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr15_+_49913201 0.25 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
DTWD1
DTW domain containing 1
chr17_-_26941179 0.25 ENST00000301037.5
ENST00000530121.1
ENST00000525510.1
ENST00000577790.1
ENST00000531839.1
ENST00000534850.1
SGK494
RP11-192H23.4
uncharacterized serine/threonine-protein kinase SgK494
Uncharacterized protein
chr15_-_83621435 0.24 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2
homer homolog 2 (Drosophila)
chr9_-_128246769 0.24 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr21_+_35107346 0.24 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr1_+_45212051 0.24 ENST00000372222.3
KIF2C
kinesin family member 2C
chr7_-_15601595 0.23 ENST00000342526.3
AGMO
alkylglycerol monooxygenase
chr7_-_37026108 0.23 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr12_-_122017542 0.23 ENST00000446152.2
KDM2B
lysine (K)-specific demethylase 2B
chr20_-_35329063 0.23 ENST00000422536.1
NDRG3
NDRG family member 3
chr11_-_33795893 0.23 ENST00000526785.1
ENST00000534136.1
ENST00000265651.3
ENST00000530401.1
ENST00000448981.2
FBXO3
F-box protein 3
chr4_+_144257915 0.23 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr10_-_82049424 0.22 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr20_-_49547731 0.22 ENST00000396029.3
ADNP
activity-dependent neuroprotector homeobox
chr17_-_19651654 0.22 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr20_-_49547910 0.22 ENST00000396032.3
ADNP
activity-dependent neuroprotector homeobox
chr2_-_225362533 0.21 ENST00000451538.1
CUL3
cullin 3
chr17_-_41984835 0.21 ENST00000520406.1
ENST00000518478.1
ENST00000522172.1
ENST00000461854.1
ENST00000521178.1
ENST00000520305.1
ENST00000523501.1
ENST00000520241.1
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr2_-_239197201 0.21 ENST00000254658.3
PER2
period circadian clock 2
chr9_-_130712995 0.21 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr17_-_36956155 0.20 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr1_-_101491319 0.20 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
DPH5
diphthamide biosynthesis 5
chr3_+_88188254 0.20 ENST00000309495.5
ZNF654
zinc finger protein 654
chr17_-_73179046 0.20 ENST00000314523.7
ENST00000420826.2
SUMO2
small ubiquitin-like modifier 2
chr8_+_110552831 0.19 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr16_+_3508063 0.19 ENST00000576787.1
ENST00000572942.1
ENST00000576916.1
ENST00000575076.1
ENST00000572131.1
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr2_+_46769798 0.19 ENST00000238738.4
RHOQ
ras homolog family member Q
chr17_-_41623075 0.19 ENST00000545089.1
ETV4
ets variant 4
chr19_-_35992780 0.19 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr17_-_19651668 0.18 ENST00000494157.2
ENST00000225740.6
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr18_+_21032781 0.18 ENST00000339486.3
RIOK3
RIO kinase 3
chr19_+_50922187 0.18 ENST00000595883.1
ENST00000597855.1
ENST00000596074.1
ENST00000439922.2
ENST00000594685.1
ENST00000270632.7
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr9_-_123639600 0.17 ENST00000373896.3
PHF19
PHD finger protein 19
chr16_+_3507985 0.17 ENST00000421765.3
ENST00000360862.5
ENST00000414063.2
ENST00000610180.1
ENST00000608993.1
NAA60
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
N-alpha-acetyltransferase 60
chr17_-_41623259 0.17 ENST00000538265.1
ENST00000591713.1
ETV4
ets variant 4
chr2_+_103378472 0.17 ENST00000412401.2
TMEM182
transmembrane protein 182
chr4_+_48807155 0.17 ENST00000504654.1
OCIAD1
OCIA domain containing 1
chr4_+_96012614 0.17 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr3_+_148447887 0.17 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr12_+_52430894 0.17 ENST00000546842.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr17_+_39975455 0.16 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr4_+_110354928 0.16 ENST00000504968.2
ENST00000399100.2
ENST00000265175.5
SEC24B
SEC24 family member B
chr1_-_167883327 0.16 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
ADCY10
adenylate cyclase 10 (soluble)
chr2_+_191208791 0.16 ENST00000423767.1
ENST00000451089.1
INPP1
inositol polyphosphate-1-phosphatase
chr1_+_45212074 0.16 ENST00000372217.1
KIF2C
kinesin family member 2C
chr10_-_65028938 0.16 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr17_-_73178599 0.16 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr10_-_65028817 0.16 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr8_+_90914073 0.15 ENST00000297438.2
OSGIN2
oxidative stress induced growth inhibitor family member 2
chr7_+_73868439 0.15 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr4_+_41937131 0.15 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
TMEM33
transmembrane protein 33
chr11_-_77185094 0.15 ENST00000278568.4
ENST00000356341.3
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr19_+_1450112 0.15 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2
adenomatosis polyposis coli 2
chr2_-_214014959 0.15 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr17_+_61851504 0.15 ENST00000359353.5
ENST00000389924.2
DDX42
DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr14_+_93260569 0.14 ENST00000163416.2
GOLGA5
golgin A5
chr7_-_45026200 0.14 ENST00000577700.1
ENST00000580458.1
ENST00000579383.1
ENST00000584686.1
ENST00000585030.1
ENST00000582727.1
SNHG15
small nucleolar RNA host gene 15 (non-protein coding)
chr1_-_114430169 0.14 ENST00000393316.3
BCL2L15
BCL2-like 15
chr5_-_43557791 0.14 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
PAIP1
poly(A) binding protein interacting protein 1
chr19_-_42947121 0.14 ENST00000601181.1
CXCL17
chemokine (C-X-C motif) ligand 17
chr14_+_60716159 0.14 ENST00000325658.3
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr17_+_76037081 0.14 ENST00000588549.1
TNRC6C
trinucleotide repeat containing 6C
chr8_+_110552337 0.14 ENST00000337573.5
EBAG9
estrogen receptor binding site associated, antigen, 9
chr6_-_64029879 0.13 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr21_+_27011584 0.13 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
JAM2
junctional adhesion molecule 2
chr4_+_144258021 0.13 ENST00000262994.4
GAB1
GRB2-associated binding protein 1
chr17_+_61851157 0.13 ENST00000578681.1
ENST00000583590.1
DDX42
DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr11_-_105948129 0.13 ENST00000526793.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr8_+_42396936 0.13 ENST00000416469.2
SMIM19
small integral membrane protein 19
chr21_-_30365136 0.12 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr14_+_93260642 0.12 ENST00000355976.2
GOLGA5
golgin A5
chr2_+_191208601 0.12 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chrX_+_9431324 0.12 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr9_-_88356733 0.12 ENST00000376083.3
AGTPBP1
ATP/GTP binding protein 1
chr17_-_61850894 0.12 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47
coiled-coil domain containing 47
chr10_-_91295304 0.11 ENST00000341233.4
ENST00000371790.4
SLC16A12
solute carrier family 16, member 12
chr4_-_65275162 0.11 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr8_-_102216925 0.11 ENST00000517844.1
ZNF706
zinc finger protein 706
chr4_+_144258288 0.11 ENST00000514639.1
GAB1
GRB2-associated binding protein 1
chr6_-_74231303 0.11 ENST00000309268.6
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr2_-_214015111 0.11 ENST00000433134.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_+_48592134 0.11 ENST00000595310.1
DKFZP779L1853
DKFZP779L1853
chr4_-_74088800 0.11 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr14_-_21489271 0.11 ENST00000553593.1
NDRG2
NDRG family member 2
chr3_+_62304648 0.10 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr12_-_113574028 0.10 ENST00000546530.1
ENST00000261729.5
RASAL1
RAS protein activator like 1 (GAP1 like)
chr17_-_34329084 0.10 ENST00000354059.4
ENST00000536149.1
CCL15
CCL14
chemokine (C-C motif) ligand 15
chemokine (C-C motif) ligand 14
chr12_+_57624085 0.10 ENST00000553474.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr2_-_98280383 0.10 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr7_-_83824449 0.09 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr16_-_70323422 0.09 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr16_+_56965960 0.09 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr19_+_35330037 0.09 ENST00000601776.1
CTC-523E23.5
CTC-523E23.5
chr4_-_21950356 0.09 ENST00000447367.2
ENST00000382152.2
KCNIP4
Kv channel interacting protein 4
chr12_-_120966943 0.09 ENST00000552443.1
ENST00000547736.1
ENST00000445328.2
ENST00000547943.1
ENST00000288532.6
COQ5
coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
chr16_-_54962625 0.09 ENST00000559432.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr14_+_60715928 0.09 ENST00000395076.4
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr2_+_183989083 0.09 ENST00000295119.4
NUP35
nucleoporin 35kDa
chr14_-_67826538 0.08 ENST00000553687.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr4_-_96470350 0.08 ENST00000504962.1
ENST00000453304.1
ENST00000506749.1
UNC5C
unc-5 homolog C (C. elegans)
chr17_-_39538550 0.08 ENST00000394001.1
KRT34
keratin 34
chr5_+_150404904 0.08 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr9_-_95298314 0.08 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr2_-_46769694 0.07 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr10_-_104211294 0.07 ENST00000239125.1
C10orf95
chromosome 10 open reading frame 95
chr2_-_101925055 0.07 ENST00000295317.3
RNF149
ring finger protein 149
chr12_+_57623477 0.07 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr19_+_33865218 0.07 ENST00000585933.2
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr14_+_102276192 0.07 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr5_-_111091948 0.07 ENST00000447165.2
NREP
neuronal regeneration related protein
chr1_+_154378049 0.07 ENST00000512471.1
IL6R
interleukin 6 receptor
chr3_-_196910721 0.07 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr3_+_141103634 0.07 ENST00000507722.1
ZBTB38
zinc finger and BTB domain containing 38
chr17_-_685493 0.07 ENST00000536578.1
ENST00000301328.5
ENST00000576419.1
GLOD4
glyoxalase domain containing 4
chr7_-_130080977 0.07 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr8_+_24151553 0.06 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr17_-_41623009 0.06 ENST00000393664.2
ETV4
ets variant 4
chr13_-_28545276 0.06 ENST00000381020.7
CDX2
caudal type homeobox 2
chr21_+_40824003 0.06 ENST00000452550.1
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr2_-_99279928 0.06 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr6_+_4706368 0.06 ENST00000328908.5
CDYL
chromodomain protein, Y-like
chr12_+_57624119 0.05 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr3_+_158787041 0.05 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr1_-_207143802 0.05 ENST00000324852.4
ENST00000400962.3
FCAMR
Fc receptor, IgA, IgM, high affinity
chr17_-_41623691 0.05 ENST00000545954.1
ETV4
ets variant 4
chr8_-_102217515 0.05 ENST00000520347.1
ENST00000523922.1
ENST00000520984.1
ZNF706
zinc finger protein 706
chr10_-_97416400 0.05 ENST00000371224.2
ENST00000371221.3
ALDH18A1
aldehyde dehydrogenase 18 family, member A1
chr1_-_226496898 0.05 ENST00000481685.1
LIN9
lin-9 homolog (C. elegans)
chr22_-_30867973 0.05 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr4_-_85654615 0.05 ENST00000514711.1
WDFY3
WD repeat and FYVE domain containing 3
chr7_+_20687017 0.05 ENST00000258738.6
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr21_+_19617140 0.04 ENST00000299295.2
ENST00000338326.3
CHODL
chondrolectin
chr2_+_191208196 0.04 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr3_+_62304712 0.03 ENST00000494481.1
C3orf14
chromosome 3 open reading frame 14
chr17_-_685559 0.03 ENST00000301329.6
GLOD4
glyoxalase domain containing 4
chr5_-_54830871 0.03 ENST00000307259.8
PPAP2A
phosphatidic acid phosphatase type 2A
chr20_+_39657454 0.03 ENST00000361337.2
TOP1
topoisomerase (DNA) I
chr17_-_41322332 0.03 ENST00000590740.1
RP11-242D8.1
RP11-242D8.1
chr3_-_48130314 0.03 ENST00000439356.1
ENST00000395734.3
ENST00000426837.2
MAP4
microtubule-associated protein 4
chr14_-_67826486 0.03 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D

Network of associatons between targets according to the STRING database.

First level regulatory network of HLF_TEF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.5 3.6 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3 1.4 GO:0002384 hepatic immune response(GO:0002384)
0.3 0.8 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 2.0 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 1.0 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.4 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 1.8 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.6 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.4 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 1.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.9 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0019249 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.4 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.6 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.2 GO:1902731 negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.5 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 0.8 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 3.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.4 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 0.7 GO:0070695 FHF complex(GO:0070695)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.0 0.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.0 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.3 1.8 GO:1903135 cupric ion binding(GO:1903135)
0.2 2.0 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 3.6 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.4 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.3 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 1.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.2 GO:0052811 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811)
0.0 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.0 1.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 4.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.4 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 3.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions