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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HIF1A

Z-value: 2.02

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Transcription factors associated with HIF1A

Gene Symbol Gene ID Gene Info
HIF1A
ENSG00000100644.12 hypoxia inducible factor 1 subunit alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIF1Ahg19_v2_chr14_+_62162258_621622690.871.3e-01Click!

Activity profile of HIF1A motif

Sorted Z-values of HIF1A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_76649546 1.81 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr10_-_93392811 1.57 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr4_-_39529049 1.34 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UGDH
UDP-glucose 6-dehydrogenase
chr4_-_39529180 1.29 ENST00000515021.1
ENST00000510490.1
ENST00000316423.6
UGDH
UDP-glucose 6-dehydrogenase
chr1_+_150254936 1.27 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr1_+_65613852 1.25 ENST00000327299.7
AK4
adenylate kinase 4
chr1_-_151319710 1.10 ENST00000290524.4
ENST00000437327.1
ENST00000452513.2
ENST00000368870.2
ENST00000452671.2
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr14_+_56046990 1.04 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
KTN1
kinectin 1 (kinesin receptor)
chr14_+_64970662 1.03 ENST00000556965.1
ENST00000554015.1
ZBTB1
zinc finger and BTB domain containing 1
chr18_+_56531584 1.02 ENST00000590287.1
ZNF532
zinc finger protein 532
chr8_+_17354617 0.99 ENST00000470360.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr12_+_6977323 0.97 ENST00000462761.1
TPI1
triosephosphate isomerase 1
chrX_+_69509870 0.97 ENST00000374388.3
KIF4A
kinesin family member 4A
chr8_+_17354587 0.94 ENST00000494857.1
ENST00000522656.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr6_-_153304148 0.94 ENST00000229758.3
FBXO5
F-box protein 5
chr6_-_109702885 0.94 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr4_-_104119528 0.94 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr6_+_108882069 0.90 ENST00000406360.1
FOXO3
forkhead box O3
chr3_+_19988885 0.89 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr1_-_26233423 0.89 ENST00000357865.2
STMN1
stathmin 1
chrX_-_84363974 0.84 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr17_+_76311791 0.84 ENST00000586321.1
AC061992.2
AC061992.2
chr6_-_153304697 0.84 ENST00000367241.3
FBXO5
F-box protein 5
chr3_-_195808952 0.84 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC
transferrin receptor
chr14_+_56046914 0.84 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr3_-_149688971 0.83 ENST00000498307.1
ENST00000489155.1
PFN2
profilin 2
chr22_-_36903069 0.83 ENST00000216187.6
ENST00000423980.1
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr6_+_64282447 0.82 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_-_151773232 0.82 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr2_+_171627597 0.82 ENST00000429172.1
ENST00000426475.1
AC007405.6
AC007405.6
chr11_-_62414070 0.81 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr15_+_52311398 0.81 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr14_-_53162215 0.80 ENST00000554251.1
ERO1L
ERO1-like (S. cerevisiae)
chr3_-_195808980 0.80 ENST00000360110.4
TFRC
transferrin receptor
chrX_+_47077680 0.80 ENST00000522883.1
CDK16
cyclin-dependent kinase 16
chr1_+_100435535 0.80 ENST00000427993.2
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr17_-_8059638 0.79 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1
period circadian clock 1
chr1_+_100436065 0.79 ENST00000370153.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr18_+_56530794 0.78 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532
zinc finger protein 532
chr17_-_67323385 0.78 ENST00000588665.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr4_+_76649753 0.75 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr14_-_23770683 0.75 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
PPP1R3E
protein phosphatase 1, regulatory subunit 3E
chr17_-_77179487 0.75 ENST00000580508.1
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr8_+_98656693 0.74 ENST00000519934.1
MTDH
metadherin
chr7_+_26331541 0.74 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr12_-_15374343 0.73 ENST00000256953.2
ENST00000546331.1
RERG
RAS-like, estrogen-regulated, growth inhibitor
chr11_+_74204395 0.72 ENST00000526036.1
AP001372.2
AP001372.2
chr7_+_94536898 0.72 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr13_+_103451399 0.72 ENST00000257336.1
ENST00000448849.2
BIVM
basic, immunoglobulin-like variable motif containing
chr4_+_153701081 0.72 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1
ADP-ribosylation factor interacting protein 1
chr14_-_54908043 0.72 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr6_+_151773583 0.72 ENST00000545879.1
C6orf211
chromosome 6 open reading frame 211
chr2_+_187350973 0.71 ENST00000544130.1
ZC3H15
zinc finger CCCH-type containing 15
chr9_-_123476612 0.71 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chrX_-_57147902 0.71 ENST00000275988.5
ENST00000434397.1
ENST00000333933.3
ENST00000374912.5
SPIN2B
spindlin family, member 2B
chr6_+_89791507 0.70 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr10_+_49514698 0.67 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chrX_+_69509927 0.67 ENST00000374403.3
KIF4A
kinesin family member 4A
chr8_+_6566206 0.67 ENST00000518327.1
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5
chr5_+_49962495 0.66 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr3_-_52719888 0.66 ENST00000458294.1
PBRM1
polybromo 1
chr6_+_44191290 0.65 ENST00000371755.3
ENST00000371740.5
ENST00000371731.1
ENST00000393841.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr8_+_109455830 0.64 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr8_+_98656336 0.64 ENST00000336273.3
MTDH
metadherin
chr4_+_76649797 0.62 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr17_+_27052892 0.62 ENST00000579671.1
ENST00000579060.1
NEK8
NIMA-related kinase 8
chr9_-_123476719 0.62 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr7_-_27170352 0.61 ENST00000428284.2
ENST00000360046.5
HOXA4
homeobox A4
chr7_+_94537542 0.61 ENST00000433881.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr3_-_50329835 0.60 ENST00000429673.2
IFRD2
interferon-related developmental regulator 2
chr5_+_78532003 0.60 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr15_+_76135622 0.60 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
UBE2Q2
ubiquitin-conjugating enzyme E2Q family member 2
chr11_-_74204742 0.60 ENST00000310109.4
LIPT2
lipoyl(octanoyl) transferase 2 (putative)
chr7_+_86781847 0.59 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
DMTF1
cyclin D binding myb-like transcription factor 1
chr9_-_124132483 0.59 ENST00000286713.2
ENST00000538954.1
ENST00000347359.2
STOM
stomatin
chr16_+_66914264 0.58 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr6_+_64281906 0.58 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr8_-_97273807 0.57 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERFD1
MTERF domain containing 1
chrX_+_100663243 0.56 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr14_-_64010006 0.56 ENST00000555899.1
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr3_+_63898275 0.56 ENST00000538065.1
ATXN7
ataxin 7
chr10_+_98592009 0.56 ENST00000540664.1
ENST00000371103.3
LCOR
ligand dependent nuclear receptor corepressor
chr4_-_492891 0.56 ENST00000338977.5
ENST00000511833.2
ZNF721
zinc finger protein 721
chr12_-_48213735 0.56 ENST00000417902.1
ENST00000417107.1
HDAC7
histone deacetylase 7
chrX_+_16804544 0.56 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr15_+_98503922 0.55 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chrX_-_41782683 0.55 ENST00000378163.1
ENST00000378154.1
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr22_+_41777927 0.54 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr2_+_187350883 0.53 ENST00000337859.6
ZC3H15
zinc finger CCCH-type containing 15
chr10_-_101945771 0.53 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr13_-_36788718 0.53 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr8_-_125551278 0.52 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TATDN1
TatD DNase domain containing 1
chr1_-_166135952 0.51 ENST00000354422.3
FAM78B
family with sequence similarity 78, member B
chr10_+_23728198 0.51 ENST00000376495.3
OTUD1
OTU domain containing 1
chr11_-_76155618 0.51 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr22_-_36903101 0.50 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr3_-_156272924 0.50 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr1_-_151319318 0.50 ENST00000436271.1
ENST00000450506.1
ENST00000422595.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr10_+_64564469 0.48 ENST00000373783.1
ADO
2-aminoethanethiol (cysteamine) dioxygenase
chr6_+_127588020 0.48 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146
ring finger protein 146
chr1_-_26232522 0.48 ENST00000399728.1
STMN1
stathmin 1
chr16_-_81129951 0.48 ENST00000315467.3
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr1_+_186798073 0.48 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr11_+_18343800 0.47 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr1_-_26232951 0.47 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr2_+_170683979 0.46 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chrX_+_105969893 0.46 ENST00000255499.2
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr12_+_28343365 0.46 ENST00000545336.1
CCDC91
coiled-coil domain containing 91
chr11_+_14665373 0.46 ENST00000455098.2
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr5_+_70883178 0.46 ENST00000323375.8
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr2_+_118846008 0.46 ENST00000245787.4
INSIG2
insulin induced gene 2
chr3_-_167813672 0.45 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr1_-_113498616 0.44 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr14_-_64010046 0.44 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr16_+_69166770 0.44 ENST00000567235.2
ENST00000568448.1
CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr2_+_242254507 0.44 ENST00000391973.2
SEPT2
septin 2
chr8_+_26240414 0.44 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr1_-_92351769 0.43 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr10_+_120789223 0.43 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chr11_+_18344106 0.43 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr15_-_74726283 0.43 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr17_+_34890807 0.42 ENST00000429467.2
ENST00000592983.1
PIGW
phosphatidylinositol glycan anchor biosynthesis, class W
chr8_+_97274119 0.42 ENST00000455950.2
PTDSS1
phosphatidylserine synthase 1
chr17_-_67323305 0.42 ENST00000392677.2
ENST00000593153.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr17_+_17942684 0.42 ENST00000376345.3
GID4
GID complex subunit 4
chr7_+_86781677 0.42 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
DMTF1
cyclin D binding myb-like transcription factor 1
chr5_+_134094461 0.41 ENST00000452510.2
ENST00000354283.4
DDX46
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr2_+_88991162 0.41 ENST00000283646.4
RPIA
ribose 5-phosphate isomerase A
chr12_+_28343353 0.41 ENST00000539107.1
CCDC91
coiled-coil domain containing 91
chr1_-_166136187 0.41 ENST00000338353.3
FAM78B
family with sequence similarity 78, member B
chr11_-_73471655 0.41 ENST00000400470.2
RAB6A
RAB6A, member RAS oncogene family
chr2_+_26915584 0.40 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr11_+_14665263 0.40 ENST00000282096.4
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr19_-_49137790 0.40 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr8_-_54755459 0.39 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr3_-_127541679 0.39 ENST00000265052.5
MGLL
monoglyceride lipase
chr19_-_17622269 0.39 ENST00000595116.1
CTD-3131K8.2
CTD-3131K8.2
chr2_+_242254679 0.39 ENST00000428282.1
ENST00000360051.3
SEPT2
septin 2
chr13_-_52027134 0.39 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr9_-_94186131 0.39 ENST00000297689.3
NFIL3
nuclear factor, interleukin 3 regulated
chr14_+_96968802 0.38 ENST00000556619.1
ENST00000392990.2
PAPOLA
poly(A) polymerase alpha
chr22_-_38577782 0.38 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr14_-_53162361 0.38 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr5_+_148960931 0.37 ENST00000333677.6
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr12_-_48213568 0.37 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
HDAC7
histone deacetylase 7
chr7_-_102985035 0.37 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr11_+_9595180 0.37 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr1_-_231376867 0.37 ENST00000366649.2
ENST00000318906.2
ENST00000366651.3
C1orf131
chromosome 1 open reading frame 131
chr3_+_19988566 0.36 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr12_+_46777450 0.36 ENST00000551503.1
RP11-96H19.1
RP11-96H19.1
chr2_-_74648702 0.36 ENST00000518863.1
C2orf81
chromosome 2 open reading frame 81
chr1_+_112162381 0.36 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A
RAP1A, member of RAS oncogene family
chr5_+_138609441 0.35 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3
matrin 3
chrX_-_47509994 0.35 ENST00000343894.4
ELK1
ELK1, member of ETS oncogene family
chr3_-_50329990 0.35 ENST00000417626.2
IFRD2
interferon-related developmental regulator 2
chr2_-_68384603 0.35 ENST00000406245.2
ENST00000409164.1
ENST00000295121.6
WDR92
WD repeat domain 92
chr2_-_40006289 0.34 ENST00000260619.6
ENST00000454352.2
THUMPD2
THUMP domain containing 2
chr8_+_95907993 0.34 ENST00000523378.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr17_+_5185552 0.34 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
RABEP1
rabaptin, RAB GTPase binding effector protein 1
chr6_-_83775489 0.34 ENST00000369747.3
UBE3D
ubiquitin protein ligase E3D
chr8_-_101734308 0.34 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr12_-_123849374 0.34 ENST00000602398.1
ENST00000602750.1
SBNO1
strawberry notch homolog 1 (Drosophila)
chrX_-_57164058 0.33 ENST00000374906.3
SPIN2A
spindlin family, member 2A
chr4_-_25161996 0.33 ENST00000513285.1
ENST00000382103.2
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr11_-_57283159 0.33 ENST00000533263.1
ENST00000278426.3
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr1_-_167522982 0.32 ENST00000370509.4
CREG1
cellular repressor of E1A-stimulated genes 1
chr16_+_30418910 0.32 ENST00000566625.1
ZNF771
zinc finger protein 771
chr8_+_109455845 0.31 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr9_-_123605177 0.31 ENST00000373904.5
ENST00000210313.3
PSMD5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
chr3_+_113666748 0.31 ENST00000330212.3
ENST00000498275.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr20_+_10015678 0.31 ENST00000378392.1
ENST00000378380.3
ANKEF1
ankyrin repeat and EF-hand domain containing 1
chr14_+_96968707 0.31 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA
poly(A) polymerase alpha
chr17_-_8534031 0.30 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
MYH10
myosin, heavy chain 10, non-muscle
chr7_-_100026280 0.30 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr17_+_7211656 0.30 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr4_-_25162188 0.30 ENST00000302922.3
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr9_+_100745615 0.29 ENST00000339399.4
ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_+_32288725 0.29 ENST00000315285.3
SPAST
spastin
chr2_+_216946589 0.29 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chr2_+_32288657 0.29 ENST00000345662.1
SPAST
spastin
chr15_-_34875771 0.28 ENST00000267731.7
GOLGA8B
golgin A8 family, member B
chr22_-_38577731 0.28 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr6_-_159240415 0.28 ENST00000367075.3
EZR
ezrin
chr11_+_76156045 0.28 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
C11orf30
chromosome 11 open reading frame 30
chr11_-_118901559 0.28 ENST00000330775.7
ENST00000545985.1
ENST00000357590.5
ENST00000538950.1
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr1_-_231376836 0.28 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chrX_-_57163430 0.28 ENST00000374908.1
SPIN2A
spindlin family, member 2A
chr10_+_93558069 0.27 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chrX_-_34675391 0.27 ENST00000275954.3
TMEM47
transmembrane protein 47
chr12_-_50677255 0.27 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1
LIM domain and actin binding 1
chr2_-_220083076 0.27 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_-_151319654 0.27 ENST00000430227.1
ENST00000412774.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr7_+_65540780 0.26 ENST00000304874.9
ASL
argininosuccinate lyase
chr1_+_246729815 0.26 ENST00000366511.1
CNST
consortin, connexin sorting protein
chr16_+_53164833 0.26 ENST00000564845.1
CHD9
chromodomain helicase DNA binding protein 9
chr11_-_73882249 0.26 ENST00000535954.1
C2CD3
C2 calcium-dependent domain containing 3
chr1_+_110162448 0.26 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
AMPD2
adenosine monophosphate deaminase 2
chr17_-_67323232 0.26 ENST00000592568.1
ENST00000392676.3
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr4_+_78079570 0.26 ENST00000509972.1
CCNG2
cyclin G2
chr12_-_64616019 0.26 ENST00000311915.8
ENST00000398055.3
ENST00000544871.1
C12orf66
chromosome 12 open reading frame 66

Network of associatons between targets according to the STRING database.

First level regulatory network of HIF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.6 1.8 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.3 1.3 GO:1904048 positive regulation of long term synaptic depression(GO:1900454) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.3 1.6 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.3 1.2 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.3 0.9 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.3 0.8 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 1.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.3 2.6 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.2 0.7 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.2 0.7 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 0.5 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.6 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 1.4 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2 1.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.6 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 1.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.6 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.6 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 1.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.8 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 1.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.6 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.9 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.8 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.8 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 1.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.3 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.1 0.3 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.3 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.2 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.5 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.4 GO:2000301 response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.4 GO:0021592 fourth ventricle development(GO:0021592)
0.1 1.5 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 0.9 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.7 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.6 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 1.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.3 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.5 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.9 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.5 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.6 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.5 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.3 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.9 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.3 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.2 GO:1903509 glycolipid metabolic process(GO:0006664) liposaccharide metabolic process(GO:1903509)
0.0 0.4 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 2.4 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 0.5 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.6 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.6 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.4 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.4 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0021510 spinal cord development(GO:0021510)
0.0 1.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005960 glycine cleavage complex(GO:0005960)
0.2 0.6 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 1.3 GO:0044326 dendritic spine neck(GO:0044326)
0.1 1.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.6 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.9 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.0 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 1.0 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.8 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0005912 adherens junction(GO:0005912)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.4 1.9 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.3 1.6 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.3 0.9 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.3 0.8 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.2 0.7 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.2 0.7 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 1.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 0.6 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.2 1.8 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 0.7 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 1.1 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.3 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.1 0.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 1.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.8 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.3 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 1.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 1.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0008494 translation activator activity(GO:0008494)
0.0 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.7 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 3.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 2.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 2.5 GO:0051287 NAD binding(GO:0051287)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 3.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.1 PID ARF 3PATHWAY Arf1 pathway
0.0 1.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.9 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 2.1 REACTOME KINESINS Genes involved in Kinesins
0.0 1.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 2.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets