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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for HBP1
Z-value: 1.53
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Transcription factors associated with HBP1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HBP1 | hg19_v2_chr7_+_106809406_106809460 | -0.71 | 2.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_4198072 Show fit | 3.58 |
ENST00000262970.5
|
ankyrin repeat domain 24 |
|
| chr7_-_92777606 Show fit | 1.17 |
ENST00000437805.1
ENST00000446959.1 ENST00000439952.1 ENST00000414791.1 ENST00000446033.1 ENST00000411955.1 ENST00000318238.4 |
sterile alpha motif domain containing 9-like |
|
| chr17_-_42988004 Show fit | 1.15 |
ENST00000586125.1
ENST00000591880.1 |
glial fibrillary acidic protein |
|
| chr5_+_156887027 Show fit | 1.12 |
ENST00000435489.2
ENST00000311946.7 |
NIPA-like domain containing 4 |
|
| chr7_-_75443118 Show fit | 1.09 |
ENST00000222902.2
|
chemokine (C-C motif) ligand 24 |
|
| chr6_+_71104588 Show fit | 1.06 |
ENST00000418403.1
|
RP11-462G2.1 |
|
| chr19_+_49055332 Show fit | 1.04 |
ENST00000201586.2
|
sulfotransferase family, cytosolic, 2B, member 1 |
|
| chr6_-_30640761 Show fit | 0.86 |
ENST00000415603.1
|
DEAH (Asp-Glu-Ala-His) box polypeptide 16 |
|
| chr14_+_102430855 Show fit | 0.83 |
ENST00000360184.4
|
dynein, cytoplasmic 1, heavy chain 1 |
|
| chr16_+_57139933 Show fit | 0.76 |
ENST00000566259.1
|
copine II |
Network of associatons between targets according to the STRING database.
First level regulatory network of HBP1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.1 | 1.2 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.2 | 1.1 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.1 | 1.1 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.3 | 1.0 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.1 | 1.0 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
| 0.0 | 1.0 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.0 | 0.9 | GO:1901748 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.1 | 0.8 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.1 | 0.8 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.8 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 0.7 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.1 | 0.7 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 0.4 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.0 | 0.4 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.0 | 0.4 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 0.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.1 | 1.2 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 1.2 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.3 | 1.1 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.0 | 1.1 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 1.0 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
| 0.0 | 0.9 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.0 | 0.8 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.2 | 0.7 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.2 | 0.7 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.9 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.8 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.6 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.3 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 0.2 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.9 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 0.8 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 0.8 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.7 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.7 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.0 | 0.7 | REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA | Genes involved in Processing of Capped Intronless Pre-mRNA |
| 0.0 | 0.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.6 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.4 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |