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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HBP1

Z-value: 1.53

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Transcription factors associated with HBP1

Gene Symbol Gene ID Gene Info
HBP1
ENSG00000105856.9 HMG-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HBP1hg19_v2_chr7_+_106809406_106809460-0.712.9e-01Click!

Activity profile of HBP1 motif

Sorted Z-values of HBP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_4198072 3.58 ENST00000262970.5
ANKRD24
ankyrin repeat domain 24
chr7_-_92777606 1.17 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr17_-_42988004 1.15 ENST00000586125.1
ENST00000591880.1
GFAP
glial fibrillary acidic protein
chr5_+_156887027 1.12 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr7_-_75443118 1.09 ENST00000222902.2
CCL24
chemokine (C-C motif) ligand 24
chr6_+_71104588 1.06 ENST00000418403.1
RP11-462G2.1
RP11-462G2.1
chr19_+_49055332 1.04 ENST00000201586.2
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr6_-_30640761 0.86 ENST00000415603.1
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr14_+_102430855 0.83 ENST00000360184.4
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr16_+_57139933 0.76 ENST00000566259.1
CPNE2
copine II
chrX_+_18725758 0.75 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr5_+_159656437 0.74 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr2_+_65663812 0.74 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr11_+_66824346 0.71 ENST00000532559.1
RHOD
ras homolog family member D
chr19_-_6690723 0.71 ENST00000601008.1
C3
complement component 3
chr20_+_45523227 0.69 ENST00000327619.5
ENST00000357410.3
EYA2
eyes absent homolog 2 (Drosophila)
chr2_-_220264703 0.68 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr16_+_80574854 0.68 ENST00000305904.6
ENST00000568035.1
DYNLRB2
dynein, light chain, roadblock-type 2
chr5_-_147211226 0.67 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr8_-_128231299 0.64 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr3_+_111805262 0.64 ENST00000484828.1
C3orf52
chromosome 3 open reading frame 52
chr16_+_15596123 0.64 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr15_+_57884117 0.63 ENST00000267853.5
MYZAP
myocardial zonula adherens protein
chr22_-_50708781 0.62 ENST00000449719.2
ENST00000330651.6
MAPK11
mitogen-activated protein kinase 11
chr6_-_44233361 0.60 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr3_-_52090461 0.58 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr11_+_73087309 0.56 ENST00000064780.2
ENST00000545687.1
RELT
RELT tumor necrosis factor receptor
chr2_+_87808725 0.56 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr10_-_134756030 0.53 ENST00000368586.5
ENST00000368582.2
TTC40
tetratricopeptide repeat domain 40
chr19_-_54579813 0.53 ENST00000446034.2
TARM1
T cell-interacting, activating receptor on myeloid cells 1
chr19_-_38806390 0.53 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr22_-_20367797 0.51 ENST00000424787.2
GGTLC3
gamma-glutamyltransferase light chain 3
chr11_+_69061594 0.50 ENST00000441339.2
ENST00000308946.3
ENST00000535407.1
MYEOV
myeloma overexpressed
chr20_-_48747662 0.49 ENST00000371656.2
TMEM189
transmembrane protein 189
chr6_+_149539053 0.48 ENST00000451095.1
RP1-111D6.3
RP1-111D6.3
chr3_+_38537960 0.48 ENST00000453767.1
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr15_+_57884086 0.48 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
GCOM1
GRINL1A complex locus 1
chr19_-_45927097 0.48 ENST00000340192.7
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_-_13213662 0.47 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1
chr20_-_56286479 0.47 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr19_-_18508396 0.45 ENST00000595840.1
ENST00000339007.3
LRRC25
leucine rich repeat containing 25
chr7_-_150721570 0.44 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B
autophagy related 9B
chr19_-_38806540 0.44 ENST00000592694.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr5_+_150040403 0.44 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr1_-_47082495 0.44 ENST00000545730.1
ENST00000531769.1
ENST00000319928.3
MKNK1
MOB3C
MAP kinase interacting serine/threonine kinase 1
MOB kinase activator 3C
chr11_-_68611721 0.43 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr1_+_113392455 0.43 ENST00000456651.1
ENST00000422022.1
RP3-522D1.1
RP3-522D1.1
chrX_+_100075368 0.43 ENST00000415585.2
ENST00000372972.2
ENST00000413437.1
CSTF2
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr21_+_45138941 0.42 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr7_-_5821314 0.41 ENST00000425013.2
ENST00000389902.3
RNF216
ring finger protein 216
chr9_-_127624194 0.41 ENST00000373570.4
ENST00000348462.3
RPL35
ribosomal protein L35
chr14_+_78266436 0.41 ENST00000557501.1
ENST00000341211.5
ADCK1
aarF domain containing kinase 1
chr11_+_122709200 0.40 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr11_+_57435441 0.40 ENST00000528177.1
ZDHHC5
zinc finger, DHHC-type containing 5
chr14_+_78266408 0.40 ENST00000238561.5
ADCK1
aarF domain containing kinase 1
chr5_-_22853429 0.39 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chrX_+_54834004 0.39 ENST00000375068.1
MAGED2
melanoma antigen family D, 2
chr3_+_111805182 0.39 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
C3orf52
chromosome 3 open reading frame 52
chr19_-_6057282 0.38 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr19_-_3500635 0.38 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr7_-_2354099 0.38 ENST00000222990.3
SNX8
sorting nexin 8
chr1_-_24126892 0.38 ENST00000374497.3
ENST00000425913.1
GALE
UDP-galactose-4-epimerase
chr10_+_104180580 0.38 ENST00000425536.1
FBXL15
F-box and leucine-rich repeat protein 15
chr11_-_7698453 0.38 ENST00000524608.1
CYB5R2
cytochrome b5 reductase 2
chr1_-_155826967 0.37 ENST00000368331.1
ENST00000361040.5
ENST00000271883.5
GON4L
gon-4-like (C. elegans)
chr4_-_69083720 0.37 ENST00000432593.3
TMPRSS11BNL
TMPRSS11B N-terminal like
chr8_+_104152922 0.37 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
BAALC
brain and acute leukemia, cytoplasmic
chr8_-_11725549 0.37 ENST00000505496.2
ENST00000534636.1
ENST00000524500.1
ENST00000345125.3
ENST00000453527.2
ENST00000527215.2
ENST00000532392.1
ENST00000533455.1
ENST00000534510.1
ENST00000530640.2
ENST00000531089.1
ENST00000532656.2
ENST00000531502.1
ENST00000434271.1
ENST00000353047.6
CTSB
cathepsin B
chr2_-_239148599 0.36 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6
hes family bHLH transcription factor 6
chr7_-_48019101 0.36 ENST00000432627.1
ENST00000258774.5
ENST00000432325.1
ENST00000446009.1
HUS1
HUS1 checkpoint homolog (S. pombe)
chr1_+_23345943 0.35 ENST00000400181.4
ENST00000542151.1
KDM1A
lysine (K)-specific demethylase 1A
chr18_+_18943554 0.35 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr1_-_24127256 0.34 ENST00000418277.1
GALE
UDP-galactose-4-epimerase
chr3_+_191046810 0.34 ENST00000392455.3
ENST00000392456.3
CCDC50
coiled-coil domain containing 50
chr19_-_38806560 0.34 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr22_-_20368028 0.34 ENST00000404912.1
GGTLC3
gamma-glutamyltransferase light chain 3
chr10_+_24528108 0.34 ENST00000438429.1
KIAA1217
KIAA1217
chr20_+_25176450 0.34 ENST00000425813.1
ENTPD6
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr1_-_53163992 0.33 ENST00000371538.3
SELRC1
cytochrome c oxidase assembly factor 7
chr20_+_13765596 0.33 ENST00000378106.5
ENST00000463598.1
NDUFAF5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr6_+_117803797 0.32 ENST00000296955.8
ENST00000368503.4
ENST00000338728.5
DCBLD1
discoidin, CUB and LCCL domain containing 1
chr19_-_38747172 0.32 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr11_+_66824276 0.32 ENST00000308831.2
RHOD
ras homolog family member D
chr6_-_30640811 0.32 ENST00000376442.3
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr5_-_140070897 0.32 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
HARS
histidyl-tRNA synthetase
chr10_-_21186144 0.31 ENST00000377119.1
NEBL
nebulette
chr3_+_37440653 0.31 ENST00000328376.5
ENST00000452017.2
C3orf35
chromosome 3 open reading frame 35
chr5_+_140762268 0.30 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr19_+_41698927 0.30 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr1_+_23345930 0.30 ENST00000356634.3
KDM1A
lysine (K)-specific demethylase 1A
chr19_-_10305752 0.29 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr20_-_48330377 0.29 ENST00000371711.4
B4GALT5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr19_+_45202421 0.29 ENST00000587331.1
CEACAM16
carcinoembryonic antigen-related cell adhesion molecule 16
chr2_-_113594279 0.29 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr7_-_149158187 0.29 ENST00000247930.4
ZNF777
zinc finger protein 777
chr1_-_85930246 0.28 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr3_+_184032419 0.28 ENST00000352767.3
ENST00000427141.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr6_-_133035185 0.28 ENST00000367928.4
VNN1
vanin 1
chr20_-_33872548 0.28 ENST00000374443.3
EIF6
eukaryotic translation initiation factor 6
chr3_+_184032283 0.28 ENST00000346169.2
ENST00000414031.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr15_+_57884199 0.27 ENST00000587652.1
ENST00000380568.3
ENST00000380565.4
ENST00000380563.2
GCOM1
MYZAP
POLR2M
GRINL1A complex locus 1
myocardial zonula adherens protein
polymerase (RNA) II (DNA directed) polypeptide M
chr12_-_12714025 0.27 ENST00000539940.1
DUSP16
dual specificity phosphatase 16
chr1_+_110577229 0.27 ENST00000369795.3
ENST00000369794.2
STRIP1
striatin interacting protein 1
chr15_-_59500973 0.27 ENST00000560749.1
MYO1E
myosin IE
chr4_+_26322185 0.27 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr11_+_63742050 0.27 ENST00000314133.3
ENST00000535431.1
COX8A
AP000721.4
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr9_+_133589333 0.26 ENST00000372348.2
ENST00000393293.4
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr19_-_45927622 0.25 ENST00000300853.3
ENST00000589165.1
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr21_+_34602200 0.25 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr17_+_33895090 0.25 ENST00000592381.1
RP11-1094M14.11
RP11-1094M14.11
chr15_-_66649010 0.25 ENST00000367709.4
ENST00000261881.4
TIPIN
TIMELESS interacting protein
chr3_+_140770183 0.25 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr15_-_86338134 0.25 ENST00000337975.5
KLHL25
kelch-like family member 25
chr12_+_57984965 0.25 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr12_-_124118151 0.24 ENST00000534960.1
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr22_+_24236191 0.24 ENST00000215754.7
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr1_-_36863481 0.24 ENST00000315732.2
LSM10
LSM10, U7 small nuclear RNA associated
chr3_+_184032313 0.24 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr19_+_34855874 0.24 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chr5_-_66942617 0.23 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr19_+_34855925 0.23 ENST00000590375.1
ENST00000356487.5
GPI
glucose-6-phosphate isomerase
chr3_+_37441062 0.23 ENST00000426078.1
C3orf35
chromosome 3 open reading frame 35
chr1_-_25291475 0.23 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr20_+_25176318 0.23 ENST00000354989.5
ENST00000360031.2
ENST00000376652.4
ENST00000439162.1
ENST00000433417.1
ENST00000417467.1
ENST00000433259.2
ENST00000427553.1
ENST00000435520.1
ENST00000418890.1
ENTPD6
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr11_-_65667884 0.23 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr5_+_148521136 0.23 ENST00000506113.1
ABLIM3
actin binding LIM protein family, member 3
chr19_-_38714847 0.23 ENST00000420980.2
ENST00000355526.4
DPF1
D4, zinc and double PHD fingers family 1
chr22_-_30956746 0.23 ENST00000437282.1
ENST00000447224.1
ENST00000427899.1
ENST00000406955.1
ENST00000452827.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chrX_+_54834159 0.23 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
MAGED2
melanoma antigen family D, 2
chr18_-_19283649 0.23 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr19_+_10713112 0.22 ENST00000590382.1
ENST00000407327.4
SLC44A2
solute carrier family 44 (choline transporter), member 2
chr12_+_57984943 0.22 ENST00000422156.3
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr9_+_127624387 0.21 ENST00000353214.2
ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr19_+_1040096 0.21 ENST00000263094.6
ENST00000524850.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr12_-_89746173 0.21 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr1_+_66797687 0.21 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr8_+_23104130 0.21 ENST00000313219.7
ENST00000519984.1
CHMP7
charged multivesicular body protein 7
chr17_-_36904437 0.21 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2
polycomb group ring finger 2
chr5_+_125758813 0.21 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr16_+_77246337 0.20 ENST00000563157.1
SYCE1L
synaptonemal complex central element protein 1-like
chr1_+_46972668 0.20 ENST00000371956.4
ENST00000360032.3
DMBX1
diencephalon/mesencephalon homeobox 1
chr17_+_6918093 0.20 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr1_+_111773349 0.20 ENST00000533831.2
CHI3L2
chitinase 3-like 2
chr2_-_30144432 0.20 ENST00000389048.3
ALK
anaplastic lymphoma receptor tyrosine kinase
chr17_-_17184605 0.20 ENST00000268717.5
COPS3
COP9 signalosome subunit 3
chr4_-_47983519 0.20 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr3_-_186288097 0.20 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr17_-_16256718 0.19 ENST00000476243.1
ENST00000299736.4
CENPV
centromere protein V
chr15_+_57891609 0.19 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr1_-_151319654 0.19 ENST00000430227.1
ENST00000412774.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr3_+_185080908 0.19 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr5_+_148521381 0.19 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr19_-_18654828 0.19 ENST00000609656.1
ENST00000597611.3
FKBP8
FK506 binding protein 8, 38kDa
chr3_+_46616017 0.19 ENST00000542931.1
TDGF1
teratocarcinoma-derived growth factor 1
chr1_-_31769595 0.19 ENST00000263694.4
SNRNP40
small nuclear ribonucleoprotein 40kDa (U5)
chr9_+_131217459 0.19 ENST00000497812.2
ENST00000393533.2
ODF2
outer dense fiber of sperm tails 2
chr7_+_99070527 0.18 ENST00000379724.3
ZNF789
zinc finger protein 789
chr10_+_104263743 0.18 ENST00000369902.3
ENST00000369899.2
ENST00000423559.2
SUFU
suppressor of fused homolog (Drosophila)
chr15_-_65407524 0.17 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr16_-_30905584 0.17 ENST00000380317.4
BCL7C
B-cell CLL/lymphoma 7C
chr15_-_55881135 0.17 ENST00000302000.6
PYGO1
pygopus family PHD finger 1
chr7_+_95115210 0.17 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr11_-_65667997 0.17 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr7_+_18536090 0.17 ENST00000441986.1
HDAC9
histone deacetylase 9
chr12_-_58146128 0.17 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4
cyclin-dependent kinase 4
chr2_+_110656005 0.17 ENST00000437679.2
LIMS3
LIM and senescent cell antigen-like domains 3
chr16_+_69140122 0.16 ENST00000219322.3
HAS3
hyaluronan synthase 3
chr2_+_65216462 0.16 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr11_+_57435219 0.16 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr1_+_240255166 0.16 ENST00000319653.9
FMN2
formin 2
chr20_-_33543546 0.15 ENST00000216951.2
GSS
glutathione synthetase
chr19_+_34856141 0.15 ENST00000586425.1
GPI
glucose-6-phosphate isomerase
chr22_+_20105259 0.15 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1
RAN binding protein 1
chr18_+_52385068 0.15 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr19_-_39390212 0.15 ENST00000437828.1
SIRT2
sirtuin 2
chr2_+_242498135 0.15 ENST00000318407.3
BOK
BCL2-related ovarian killer
chr10_-_17243579 0.15 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
TRDMT1
tRNA aspartic acid methyltransferase 1
chr19_-_42806919 0.15 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr10_+_35464513 0.15 ENST00000494479.1
ENST00000463314.1
ENST00000342105.3
ENST00000495301.1
ENST00000463960.1
CREM
cAMP responsive element modulator
chr22_-_18256742 0.15 ENST00000317361.7
BID
BH3 interacting domain death agonist
chr15_+_72410660 0.15 ENST00000564082.1
SENP8
SUMO/sentrin specific peptidase family member 8
chr3_+_100428268 0.14 ENST00000240851.4
TFG
TRK-fused gene
chr4_-_119757239 0.14 ENST00000280551.6
SEC24D
SEC24 family member D
chrX_+_23925918 0.14 ENST00000379211.3
CXorf58
chromosome X open reading frame 58
chr1_+_150039369 0.14 ENST00000369130.3
ENST00000369128.5
VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr2_+_101618691 0.14 ENST00000409000.1
ENST00000409028.4
ENST00000409320.3
ENST00000409733.1
ENST00000409650.1
ENST00000409038.1
RPL31
ribosomal protein L31
chr20_+_18125727 0.14 ENST00000489634.2
CSRP2BP
CSRP2 binding protein
chr4_+_25162253 0.14 ENST00000512921.1
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr12_-_89746264 0.14 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr14_+_88471468 0.14 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr4_+_186347388 0.13 ENST00000511138.1
ENST00000511581.1
C4orf47
chromosome 4 open reading frame 47
chr19_-_38746979 0.13 ENST00000591291.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr3_+_126423045 0.13 ENST00000290913.3
ENST00000508789.1
CHCHD6
coiled-coil-helix-coiled-coil-helix domain containing 6
chr1_+_12976450 0.13 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr2_-_40739501 0.13 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr7_+_120702819 0.13 ENST00000423795.1
CPED1
cadherin-like and PC-esterase domain containing 1
chr7_+_128349106 0.13 ENST00000485070.1
FAM71F1
family with sequence similarity 71, member F1
chr12_-_11214893 0.13 ENST00000533467.1
TAS2R46
taste receptor, type 2, member 46
chr11_+_22689648 0.13 ENST00000278187.3
GAS2
growth arrest-specific 2
chr4_-_186697044 0.12 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.7 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 1.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.4 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.3 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.1 1.0 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.8 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.7 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 0.6 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.7 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.3 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.4 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.2 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.6 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 1.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.2 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.2 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.3 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 1.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.6 GO:0042940 D-amino acid transport(GO:0042940)
0.1 0.2 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.8 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.9 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.7 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.3 GO:0031622 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622) negative regulation of adiponectin secretion(GO:0070164)
0.0 0.5 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.3 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:1901295 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 1.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.3 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868) L-cystine transport(GO:0015811)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.1 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.4 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.7 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 0.7 GO:0032052 bile acid binding(GO:0032052)
0.2 0.7 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.2 0.7 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 1.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 0.4 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.7 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.4 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.2 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.6 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 1.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 1.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.7 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression