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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for GMEB2
Z-value: 2.83
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Transcription factors associated with GMEB2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GMEB2 | hg19_v2_chr20_-_62258394_62258464 | 0.48 | 5.2e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of GMEB2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 4.3 | GO:1903615 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.2 | 4.1 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.4 | 3.5 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.1 | 2.4 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.3 | 2.1 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.0 | 2.1 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 2.0 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.3 | 1.9 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.0 | 1.9 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.1 | 1.8 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.1 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 3.1 | GO:0044438 | microbody part(GO:0044438) peroxisomal part(GO:0044439) |
| 0.0 | 2.8 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.1 | 2.4 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.3 | 1.8 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.4 | 1.7 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.1 | 1.7 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 1.6 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 1.6 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.0 | 1.6 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.8 | 4.1 | GO:0050115 | myosin-light-chain-phosphatase activity(GO:0050115) |
| 0.6 | 3.5 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.0 | 2.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 2.6 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 2.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 2.0 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.1 | 1.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.9 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 1.9 | GO:0048029 | monosaccharide binding(GO:0048029) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.7 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 2.4 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 2.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 2.1 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 1.4 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 1.4 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 1.3 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 1.3 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 1.3 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 1.1 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 4.5 | REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION | Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription |
| 0.1 | 4.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 4.1 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 2.4 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.1 | 1.9 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 1.8 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 1.6 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 1.5 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 1.3 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |