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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for GMEB1
Z-value: 2.00
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Transcription factors associated with GMEB1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GMEB1 | hg19_v2_chr1_+_28995258_28995322 | 0.47 | 5.3e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of GMEB1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.2 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.2 | 2.2 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 0.0 | 2.0 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.4 | 1.6 | GO:0019860 | uracil metabolic process(GO:0019860) |
| 0.1 | 1.6 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.0 | 1.5 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.0 | 1.4 | GO:0007077 | mitotic nuclear envelope disassembly(GO:0007077) |
| 0.1 | 1.3 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.2 | 1.2 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.1 | 1.2 | GO:0006657 | CDP-choline pathway(GO:0006657) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0044439 | microbody part(GO:0044438) peroxisomal part(GO:0044439) |
| 0.1 | 2.0 | GO:0000235 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 0.0 | 1.7 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.2 | 1.5 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.5 | 1.4 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 0.2 | 1.2 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.1 | 1.2 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.1 | 1.2 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 1.2 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 1.1 | GO:0032156 | septin cytoskeleton(GO:0032156) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 1.7 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 1.3 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.3 | 1.2 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) |
| 0.2 | 1.2 | GO:0050115 | myosin-light-chain-phosphatase activity(GO:0050115) |
| 0.0 | 1.2 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.4 | 1.1 | GO:0061663 | NEDD8 ligase activity(GO:0061663) |
| 0.2 | 1.0 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 0.2 | 1.0 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.1 | 1.0 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 2.8 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 2.1 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 1.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.4 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.0 | 1.4 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 1.0 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.9 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 0.7 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 0.7 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.7 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 4.5 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 2.0 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 1.5 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 1.5 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 1.5 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 1.2 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.0 | 1.2 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 1.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 1.1 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |