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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for GLIS2
Z-value: 1.47
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Transcription factors associated with GLIS2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GLIS2 | hg19_v2_chr16_+_4382225_4382225 | -0.40 | 6.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_667759 Show fit | 1.05 |
ENST00000594226.1
|
Uncharacterized protein |
|
| chr18_-_59274139 Show fit | 0.81 |
ENST00000586949.1
|
RP11-879F14.2 |
|
| chr19_+_38880695 Show fit | 0.78 |
ENST00000587947.1
ENST00000338502.4 |
sprouty-related, EVH1 domain containing 3 |
|
| chr12_-_123634449 Show fit | 0.76 |
ENST00000542210.1
|
phosphatidylinositol transfer protein, membrane-associated 2 |
|
| chr2_+_177001685 Show fit | 0.69 |
ENST00000432796.2
|
homeobox D3 |
|
| chr7_-_130080818 Show fit | 0.64 |
ENST00000343969.5
ENST00000541543.1 ENST00000489512.1 |
centrosomal protein 41kDa |
|
| chr1_-_156675564 Show fit | 0.63 |
ENST00000368220.1
|
cellular retinoic acid binding protein 2 |
|
| chr17_-_41132088 Show fit | 0.61 |
ENST00000591916.1
ENST00000451885.2 ENST00000454303.1 |
prostaglandin E synthase 3 (cytosolic)-like PTGES3L-AARSD1 readthrough |
|
| chr15_-_90233907 Show fit | 0.61 |
ENST00000561224.1
|
peroxisomal biogenesis factor 11 alpha |
|
| chr10_-_9801179 Show fit | 0.55 |
ENST00000419836.1
|
RP5-1051H14.2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GLIS2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0002138 | retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102) |
| 0.3 | 0.8 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) |
| 0.1 | 0.7 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 0.1 | 0.7 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.1 | 0.7 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.7 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.0 | 0.7 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.0 | 0.7 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 0.6 | GO:0051412 | response to corticosterone(GO:0051412) |
| 0.1 | 0.5 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.6 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.0 | 0.5 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.5 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.1 | 0.4 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.1 | 0.4 | GO:0019034 | viral replication complex(GO:0019034) |
| 0.1 | 0.4 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.1 | 0.4 | GO:0032044 | DSIF complex(GO:0032044) |
| 0.0 | 0.4 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.0 | 0.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0016918 | retinal binding(GO:0016918) |
| 0.1 | 0.8 | GO:0055104 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.1 | 0.8 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.7 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.6 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.1 | 0.5 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.1 | 0.4 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.0 | 0.4 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.0 | 0.4 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.0 | 0.4 | GO:0005243 | gap junction channel activity(GO:0005243) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 0.4 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.3 | PID ALK2 PATHWAY | ALK2 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.7 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.7 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 0.5 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.4 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 0.0 | 0.4 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.4 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 0.3 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.3 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |