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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for GCM2

Z-value: 1.05

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Transcription factors associated with GCM2

Gene Symbol Gene ID Gene Info
GCM2
ENSG00000124827.6 glial cells missing transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GCM2hg19_v2_chr6_-_10882174_108822740.544.6e-01Click!

Activity profile of GCM2 motif

Sorted Z-values of GCM2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_101389945 0.55 ENST00000561231.1
ENST00000559331.1
ENST00000558254.1
RP11-66B24.2
RP11-66B24.2
chr2_+_121493717 0.53 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr1_+_20878932 0.47 ENST00000332947.4
FAM43B
family with sequence similarity 43, member B
chr1_+_28199047 0.45 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
THEMIS2
thymocyte selection associated family member 2
chr9_-_16276311 0.42 ENST00000380685.1
C9orf92
chromosome 9 open reading frame 92
chr1_+_156698743 0.39 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr22_+_31489344 0.37 ENST00000404574.1
SMTN
smoothelin
chr16_+_1031762 0.36 ENST00000293894.3
SOX8
SRY (sex determining region Y)-box 8
chr19_+_36132631 0.36 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr18_+_3449695 0.36 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr19_-_37178284 0.36 ENST00000425254.2
ENST00000590952.1
ENST00000433232.1
AC074138.3
AC074138.3
chr18_+_3449821 0.34 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr20_+_44421137 0.34 ENST00000415790.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr17_+_7517264 0.32 ENST00000593717.1
ENST00000572182.1
ENST00000574539.1
ENST00000576728.1
ENST00000575314.1
ENST00000570547.1
ENST00000572262.1
ENST00000576478.1
AC007421.1
SHBG
AC007421.1
sex hormone-binding globulin
chr1_+_43824577 0.30 ENST00000310955.6
CDC20
cell division cycle 20
chr17_+_79989500 0.29 ENST00000306897.4
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr1_+_43824669 0.29 ENST00000372462.1
CDC20
cell division cycle 20
chr5_-_141257954 0.29 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr19_+_6361841 0.29 ENST00000596605.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr8_-_145559943 0.27 ENST00000332135.4
SCRT1
scratch family zinc finger 1
chr17_-_4806369 0.27 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr14_-_50053081 0.26 ENST00000396020.3
ENST00000245458.6
RPS29
ribosomal protein S29
chr19_-_10426663 0.26 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
FDX1L
ferredoxin 1-like
chr6_-_31239846 0.26 ENST00000415537.1
ENST00000376228.5
ENST00000383329.3
HLA-C
major histocompatibility complex, class I, C
chr1_-_67600639 0.26 ENST00000544837.1
ENST00000603691.1
C1orf141
chromosome 1 open reading frame 141
chr15_-_75248954 0.25 ENST00000499788.2
RPP25
ribonuclease P/MRP 25kDa subunit
chr17_-_41132010 0.25 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1
PTGES3L-AARSD1 readthrough
chr17_+_17206635 0.23 ENST00000389022.4
NT5M
5',3'-nucleotidase, mitochondrial
chr20_-_45976816 0.23 ENST00000441977.1
ZMYND8
zinc finger, MYND-type containing 8
chr6_-_31864977 0.23 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr2_+_12857015 0.22 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr1_+_44444865 0.22 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr9_-_130635741 0.22 ENST00000223836.10
AK1
adenylate kinase 1
chr16_+_57438679 0.21 ENST00000219244.4
CCL17
chemokine (C-C motif) ligand 17
chr1_-_156698591 0.21 ENST00000368219.1
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr16_+_2059872 0.21 ENST00000567649.1
NPW
neuropeptide W
chr15_+_44069276 0.21 ENST00000381359.1
SERF2
small EDRK-rich factor 2
chr11_-_117102768 0.20 ENST00000532301.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr20_+_44420570 0.20 ENST00000372622.3
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr3_+_43328004 0.20 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK
SNF related kinase
chr2_+_233243233 0.20 ENST00000392027.2
ALPP
alkaline phosphatase, placental
chr22_-_24181174 0.19 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr22_+_19710468 0.19 ENST00000366425.3
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr1_+_77748756 0.19 ENST00000478407.1
AK5
adenylate kinase 5
chr20_-_44420507 0.19 ENST00000243938.4
WFDC3
WAP four-disulfide core domain 3
chr3_+_184032919 0.19 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr6_-_150039170 0.19 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr17_+_28256874 0.18 ENST00000541045.1
ENST00000536908.2
EFCAB5
EF-hand calcium binding domain 5
chr14_-_60097297 0.18 ENST00000395090.1
RTN1
reticulon 1
chr17_-_71258019 0.18 ENST00000344935.4
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr19_+_36347787 0.18 ENST00000347900.6
ENST00000360202.5
KIRREL2
kin of IRRE like 2 (Drosophila)
chr17_-_76899275 0.18 ENST00000322630.2
ENST00000586713.1
DDC8
Protein DDC8 homolog
chr16_+_2564254 0.18 ENST00000565223.1
ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr20_+_1115821 0.18 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr2_-_220408430 0.18 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr14_-_105635090 0.18 ENST00000331782.3
ENST00000347004.2
JAG2
jagged 2
chr19_+_19626531 0.18 ENST00000507754.4
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr11_+_64002292 0.18 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr20_+_44420617 0.18 ENST00000449078.1
ENST00000456939.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr16_+_30759700 0.17 ENST00000328273.7
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr2_+_73114489 0.17 ENST00000234454.5
SPR
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
chr11_+_64001962 0.17 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr7_+_12726623 0.17 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chr18_-_29264669 0.17 ENST00000306851.5
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr8_-_67874805 0.17 ENST00000563496.1
TCF24
transcription factor 24
chr19_-_10676666 0.17 ENST00000539027.1
ENST00000543682.1
ENST00000361821.5
ENST00000312962.6
KRI1
KRI1 homolog (S. cerevisiae)
chr6_+_7107999 0.17 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr19_-_2236246 0.17 ENST00000587394.2
PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr11_+_64009072 0.17 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr22_-_31741757 0.17 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr19_+_2236509 0.16 ENST00000221494.5
SF3A2
splicing factor 3a, subunit 2, 66kDa
chr19_-_46288917 0.16 ENST00000537879.1
ENST00000596586.1
ENST00000595946.1
DMWD
AC011530.4
dystrophia myotonica, WD repeat containing
Uncharacterized protein
chr16_-_2059797 0.15 ENST00000563630.1
ZNF598
zinc finger protein 598
chr22_-_20307532 0.15 ENST00000405465.3
ENST00000248879.3
DGCR6L
DiGeorge syndrome critical region gene 6-like
chr19_-_5720248 0.15 ENST00000360614.3
LONP1
lon peptidase 1, mitochondrial
chr22_-_29457832 0.14 ENST00000216071.4
C22orf31
chromosome 22 open reading frame 31
chr1_-_156698181 0.14 ENST00000313146.6
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr9_+_131873659 0.14 ENST00000452489.2
ENST00000347048.4
ENST00000357197.4
ENST00000445241.1
ENST00000355007.3
ENST00000414331.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr1_+_895930 0.14 ENST00000338591.3
KLHL17
kelch-like family member 17
chr14_+_77647966 0.14 ENST00000554766.1
TMEM63C
transmembrane protein 63C
chr15_+_40733387 0.13 ENST00000416165.1
BAHD1
bromo adjacent homology domain containing 1
chr2_+_220309379 0.13 ENST00000451076.1
SPEG
SPEG complex locus
chr3_+_122785895 0.13 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr1_-_228613026 0.13 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr5_+_137774706 0.13 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2
receptor accessory protein 2
chr6_+_31633902 0.13 ENST00000375865.2
ENST00000375866.2
CSNK2B
casein kinase 2, beta polypeptide
chr7_-_127672146 0.13 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr16_-_2059748 0.13 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr3_+_35681728 0.13 ENST00000421492.1
ENST00000458225.1
ENST00000337271.5
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr14_+_103394963 0.13 ENST00000559525.1
ENST00000559789.1
AMN
amnion associated transmembrane protein
chrX_-_71792477 0.13 ENST00000421523.1
ENST00000415409.1
ENST00000373559.4
ENST00000373556.3
ENST00000373560.2
ENST00000373583.1
ENST00000429103.2
ENST00000373571.1
ENST00000373554.1
HDAC8
histone deacetylase 8
chr20_-_23731569 0.13 ENST00000304749.2
CST1
cystatin SN
chr19_-_14316980 0.13 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr19_+_36208877 0.13 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B
Histone-lysine N-methyltransferase 2B
chr6_+_125283566 0.13 ENST00000521654.2
RNF217
ring finger protein 217
chr7_-_98467489 0.12 ENST00000416379.2
TMEM130
transmembrane protein 130
chr5_-_32313019 0.12 ENST00000280285.5
ENST00000264934.5
MTMR12
myotubularin related protein 12
chr11_+_57435441 0.12 ENST00000528177.1
ZDHHC5
zinc finger, DHHC-type containing 5
chr16_+_30751953 0.12 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr14_-_24912047 0.12 ENST00000553930.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr7_+_150811705 0.12 ENST00000335367.3
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr15_-_41408409 0.11 ENST00000361937.3
INO80
INO80 complex subunit
chr22_-_43090992 0.11 ENST00000401850.1
A4GALT
alpha 1,4-galactosyltransferase
chr6_+_31633833 0.11 ENST00000375882.2
ENST00000375880.2
CSNK2B
CSNK2B-LY6G5B-1181
casein kinase 2, beta polypeptide
Uncharacterized protein
chr11_-_83393429 0.11 ENST00000426717.2
DLG2
discs, large homolog 2 (Drosophila)
chr1_+_214161272 0.11 ENST00000498508.2
ENST00000366958.4
PROX1
prospero homeobox 1
chr14_+_92980111 0.11 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr1_+_155179012 0.11 ENST00000609421.1
MTX1
metaxin 1
chr16_+_30759563 0.11 ENST00000563588.1
ENST00000565924.1
ENST00000424889.3
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr14_-_75536182 0.11 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr7_-_5463175 0.11 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chr22_-_30662828 0.11 ENST00000403463.1
ENST00000215781.2
OSM
oncostatin M
chr14_+_23352374 0.10 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr1_-_53686261 0.10 ENST00000294360.4
C1orf123
chromosome 1 open reading frame 123
chr3_+_35681081 0.10 ENST00000428373.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr11_+_66406149 0.10 ENST00000578778.1
ENST00000483858.1
ENST00000398692.4
ENST00000510173.2
ENST00000506523.2
ENST00000530235.1
ENST00000532968.1
RBM4
RNA binding motif protein 4
chr11_-_6341724 0.10 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr11_-_83393457 0.10 ENST00000404783.3
DLG2
discs, large homolog 2 (Drosophila)
chr7_-_143929936 0.10 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr2_+_16080659 0.10 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr10_-_102790852 0.10 ENST00000470414.1
ENST00000370215.3
PDZD7
PDZ domain containing 7
chr3_-_11762202 0.10 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4
vestigial like 4 (Drosophila)
chr12_-_56122124 0.10 ENST00000552754.1
CD63
CD63 molecule
chr19_-_2236290 0.10 ENST00000591099.2
ENST00000586608.2
ENST00000326631.2
ENST00000587962.2
PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr19_+_17581253 0.10 ENST00000252595.7
ENST00000598424.1
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr6_+_46761118 0.10 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr18_+_3450161 0.09 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr15_+_40861487 0.09 ENST00000315616.7
ENST00000559271.1
RPUSD2
RNA pseudouridylate synthase domain containing 2
chr1_-_223537475 0.09 ENST00000344029.6
ENST00000494793.2
ENST00000366878.4
ENST00000366877.3
SUSD4
sushi domain containing 4
chr16_+_20911174 0.09 ENST00000568663.1
LYRM1
LYR motif containing 1
chr9_+_135037334 0.09 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2
netrin G2
chr1_+_156698708 0.09 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr1_+_156698234 0.09 ENST00000368218.4
ENST00000368216.4
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr2_-_220435963 0.09 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr2_+_220299547 0.09 ENST00000312358.7
SPEG
SPEG complex locus
chr1_-_27226928 0.09 ENST00000361720.5
GPATCH3
G patch domain containing 3
chr16_-_25122735 0.09 ENST00000563176.1
RP11-449H11.1
RP11-449H11.1
chr12_+_5019061 0.09 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr15_+_68115895 0.08 ENST00000554240.1
SKOR1
SKI family transcriptional corepressor 1
chr11_-_73882029 0.08 ENST00000539061.1
C2CD3
C2 calcium-dependent domain containing 3
chr7_-_151329416 0.08 ENST00000418337.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr12_-_49582593 0.08 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr1_-_155658085 0.08 ENST00000311573.5
ENST00000438245.2
YY1AP1
YY1 associated protein 1
chr17_-_8021710 0.08 ENST00000380149.1
ENST00000448843.2
ALOXE3
arachidonate lipoxygenase 3
chr19_-_12886327 0.08 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2
hook microtubule-tethering protein 2
chr7_+_99933730 0.08 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr11_-_62689046 0.08 ENST00000306960.3
ENST00000543973.1
CHRM1
cholinergic receptor, muscarinic 1
chr11_-_72433346 0.08 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_+_589893 0.08 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr14_+_24769043 0.08 ENST00000267425.3
ENST00000396802.3
NOP9
NOP9 nucleolar protein
chr2_-_193059250 0.08 ENST00000409056.3
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr1_-_159893507 0.08 ENST00000368096.1
TAGLN2
transgelin 2
chr2_+_233271546 0.08 ENST00000295453.3
ALPPL2
alkaline phosphatase, placental-like 2
chr19_+_44085189 0.08 ENST00000562365.2
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr15_+_74421961 0.08 ENST00000565159.1
ENST00000567206.1
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr19_+_19496728 0.08 ENST00000537887.1
ENST00000417582.2
GATAD2A
GATA zinc finger domain containing 2A
chr14_-_24911971 0.08 ENST00000555365.1
ENST00000399395.3
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr6_-_31633624 0.08 ENST00000375895.2
ENST00000375900.4
GPANK1
G patch domain and ankyrin repeats 1
chr17_-_7218631 0.08 ENST00000577040.2
ENST00000389167.5
ENST00000391950.3
GPS2
G protein pathway suppressor 2
chr17_-_7197881 0.08 ENST00000007699.5
YBX2
Y box binding protein 2
chr17_-_42908155 0.08 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr12_+_56390964 0.07 ENST00000356124.4
ENST00000266971.3
ENST00000394115.2
ENST00000547586.1
ENST00000552258.1
ENST00000548274.1
ENST00000546833.1
SUOX
sulfite oxidase
chr16_+_25123041 0.07 ENST00000399069.3
ENST00000380966.4
LCMT1
leucine carboxyl methyltransferase 1
chr15_+_78799895 0.07 ENST00000408962.2
ENST00000388988.4
ENST00000360519.3
HYKK
hydroxylysine kinase
chr5_+_139493665 0.07 ENST00000331327.3
PURA
purine-rich element binding protein A
chr14_-_60097524 0.07 ENST00000342503.4
RTN1
reticulon 1
chr7_-_150754935 0.07 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr2_-_219134822 0.07 ENST00000444053.1
ENST00000248450.4
AAMP
angio-associated, migratory cell protein
chr11_-_17099194 0.07 ENST00000533969.1
ENST00000228140.2
ENST00000525634.1
RPS13
ribosomal protein S13
chr15_-_93632421 0.07 ENST00000329082.7
RGMA
repulsive guidance molecule family member a
chr15_+_74466744 0.07 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr1_+_17944832 0.07 ENST00000167825.4
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr20_-_982904 0.07 ENST00000217260.4
ENST00000400634.2
RSPO4
R-spondin 4
chr3_-_121740969 0.07 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr1_+_150522222 0.07 ENST00000369039.5
ADAMTSL4
ADAMTS-like 4
chr11_+_66406088 0.07 ENST00000310092.7
ENST00000396053.4
ENST00000408993.2
RBM4
RNA binding motif protein 4
chr5_+_134240588 0.07 ENST00000254908.6
PCBD2
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr9_+_103340354 0.07 ENST00000307584.5
MURC
muscle-related coiled-coil protein
chr2_+_179059365 0.07 ENST00000190611.4
OSBPL6
oxysterol binding protein-like 6
chr15_-_88799384 0.07 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr15_-_41408339 0.07 ENST00000401393.3
INO80
INO80 complex subunit
chr7_-_44365216 0.07 ENST00000358707.3
ENST00000457475.1
ENST00000440254.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr7_-_8301768 0.06 ENST00000265577.7
ICA1
islet cell autoantigen 1, 69kDa
chr9_+_96338647 0.06 ENST00000359246.4
PHF2
PHD finger protein 2
chr11_-_64410787 0.06 ENST00000301894.2
NRXN2
neurexin 2
chr2_-_40739501 0.06 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr12_-_50222187 0.06 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr5_-_176738883 0.06 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
MXD3
MAX dimerization protein 3
chr1_+_17944806 0.06 ENST00000375408.3
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr16_+_30759844 0.06 ENST00000565897.1
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr8_-_144897138 0.06 ENST00000377533.3
SCRIB
scribbled planar cell polarity protein
chr15_+_78556809 0.06 ENST00000343789.3
ENST00000394852.3
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr22_-_30783356 0.06 ENST00000382363.3
RNF215
ring finger protein 215
chr19_+_35491174 0.06 ENST00000317991.5
ENST00000504615.2
GRAMD1A
GRAM domain containing 1A
chr11_+_5509915 0.06 ENST00000322641.5
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr19_-_49016847 0.06 ENST00000598924.1
CTC-273B12.10
CTC-273B12.10
chr6_-_41909191 0.06 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr5_+_140743859 0.06 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr19_+_10531150 0.06 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_+_111788738 0.06 ENST00000529342.1
C11orf52
chromosome 11 open reading frame 52

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.4 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.4 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1 0.3 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.2 GO:0006173 dADP biosynthetic process(GO:0006173)
0.1 0.2 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.3 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:0046078 dUMP metabolic process(GO:0046078)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.6 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.2 GO:0033211 positive regulation of activin receptor signaling pathway(GO:0032927) adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0014041 regulation of neuron maturation(GO:0014041)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.0 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.0 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) mesonephric duct morphogenesis(GO:0072180) pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.2 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.3 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.0 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity