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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for GCM1
Z-value: 1.02
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Transcription factors associated with GCM1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GCM1 | hg19_v2_chr6_-_53013620_53013644 | -0.73 | 2.7e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of GCM1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.0 | 1.4 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.3 | 1.3 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.1 | 1.3 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.0 | 1.1 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.3 | 0.8 | GO:0033319 | UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320) |
| 0.0 | 0.8 | GO:0071498 | cellular response to fluid shear stress(GO:0071498) |
| 0.0 | 0.7 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
| 0.2 | 0.6 | GO:1990697 | protein depalmitoleylation(GO:1990697) |
| 0.0 | 0.6 | GO:0007263 | nitric oxide mediated signal transduction(GO:0007263) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.1 | 1.3 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 0.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 0.5 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.4 | GO:0055028 | cortical microtubule(GO:0055028) |
| 0.0 | 0.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 0.3 | GO:0034706 | sodium channel complex(GO:0034706) |
| 0.0 | 0.3 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.0 | 0.2 | GO:0071665 | gamma-catenin-TCF7L2 complex(GO:0071665) |
| 0.0 | 0.2 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.3 | GO:0038131 | neuregulin receptor activity(GO:0038131) |
| 0.0 | 1.3 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.3 | 0.8 | GO:0048040 | UDP-glucuronate decarboxylase activity(GO:0048040) |
| 0.1 | 0.7 | GO:0004645 | phosphorylase activity(GO:0004645) |
| 0.2 | 0.6 | GO:1990699 | palmitoleyl hydrolase activity(GO:1990699) |
| 0.0 | 0.6 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.1 | 0.5 | GO:0004945 | angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945) |
| 0.0 | 0.4 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 0.0 | 0.4 | GO:0036042 | lipoprotein lipase activity(GO:0004465) long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.0 | 0.4 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.6 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.4 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 1.1 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.0 | 0.8 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.4 | REACTOME DEFENSINS | Genes involved in Defensins |
| 0.0 | 0.4 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 0.4 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.2 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.0 | 0.2 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 0.2 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 0.1 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |