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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for GAUAUGU

Z-value: 0.45

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miRNA associated with seed GAUAUGU

NamemiRBASE accession
hsa-miR-190a-5p
MIMAT0000458
hsa-miR-190b
MIMAT0004929

Activity profile of GAUAUGU motif

Sorted Z-values of GAUAUGU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_23712312 0.31 ENST00000290271.2
STC1
stanniocalcin 1
chr11_-_31839488 0.28 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6
paired box 6
chr14_+_55034599 0.28 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr2_-_182545603 0.24 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr11_-_70507901 0.19 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr8_-_141645645 0.17 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chr3_+_11314099 0.17 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
ATG7
autophagy related 7
chr6_-_91006461 0.17 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chrX_-_33146477 0.14 ENST00000378677.2
DMD
dystrophin
chr8_-_122653630 0.12 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr8_+_61591337 0.12 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr3_+_173116225 0.11 ENST00000457714.1
NLGN1
neuroligin 1
chr2_+_179059365 0.10 ENST00000190611.4
OSBPL6
oxysterol binding protein-like 6
chr14_+_79745746 0.10 ENST00000281127.7
NRXN3
neurexin 3
chr10_-_131762105 0.09 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr18_-_53255766 0.09 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr19_-_5340730 0.08 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS
protein tyrosine phosphatase, receptor type, S
chr15_-_45815005 0.08 ENST00000261867.4
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr1_-_33283754 0.07 ENST00000373477.4
YARS
tyrosyl-tRNA synthetase
chr2_+_149402553 0.07 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr10_+_125425871 0.06 ENST00000284674.1
GPR26
G protein-coupled receptor 26
chr16_+_24741013 0.06 ENST00000315183.7
ENST00000395799.3
TNRC6A
trinucleotide repeat containing 6A
chr13_+_49550015 0.05 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr19_-_33793430 0.05 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr11_-_30038490 0.05 ENST00000328224.6
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr18_-_35145593 0.05 ENST00000334919.5
ENST00000591282.1
ENST00000588597.1
CELF4
CUGBP, Elav-like family member 4
chr6_+_73331776 0.04 ENST00000370398.1
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr1_+_145470504 0.04 ENST00000323397.4
ANKRD34A
ankyrin repeat domain 34A
chr3_-_126076264 0.03 ENST00000296233.3
KLF15
Kruppel-like factor 15
chr11_-_106889250 0.03 ENST00000526355.2
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr7_+_5085452 0.03 ENST00000353796.3
ENST00000396912.1
ENST00000396904.2
RBAK
RBAK-RBAKDN
RB-associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr12_-_102874416 0.03 ENST00000392904.1
ENST00000337514.6
IGF1
insulin-like growth factor 1 (somatomedin C)
chr7_+_114055052 0.03 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr8_-_93115445 0.02 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_228336849 0.02 ENST00000409979.2
ENST00000310078.8
AGFG1
ArfGAP with FG repeats 1
chr13_-_103053946 0.02 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr15_-_52821247 0.02 ENST00000399231.3
ENST00000399233.2
MYO5A
myosin VA (heavy chain 12, myoxin)
chr22_+_40573921 0.02 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr20_+_56964169 0.01 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr7_-_26240357 0.01 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr2_+_208394616 0.00 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GAUAUGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.1 0.2 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.2 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0021553 right ventricular cardiac muscle tissue morphogenesis(GO:0003221) olfactory nerve development(GO:0021553)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells