Project
A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for FOXK1_FOXP2_FOXB1_FOXP3
Z-value: 1.49
Motif logo
Transcription factors associated with FOXK1_FOXP2_FOXB1_FOXP3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSG00000164916.9 | forkhead box K1 | |
| ENSG00000128573.18 | forkhead box P2 | |
| ENSG00000171956.5 | forkhead box B1 | |
| ENSG00000049768.10 | forkhead box P3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXK1 | hg19_v2_chr7_+_4721885_4721945 | -0.87 | 1.3e-01 | Click! |
| FOXB1 | hg19_v2_chr15_+_60296421_60296464 | -0.46 | 5.4e-01 | Click! |
| FOXP3 | hg19_v2_chrX_-_49121165_49121288 | -0.29 | 7.1e-01 | Click! |
| FOXP2 | hg19_v2_chr7_+_114055052_114055378 | 0.07 | 9.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_101841588 Show fit | 4.88 |
ENST00000370418.3
|
carboxypeptidase N, polypeptide 1 |
|
| chr12_-_71551652 Show fit | 3.03 |
ENST00000546561.1
|
tetraspanin 8 |
|
| chr17_-_46035187 Show fit | 2.90 |
ENST00000300557.2
|
proline rich 15-like |
|
| chr12_-_71551868 Show fit | 2.23 |
ENST00000247829.3
|
tetraspanin 8 |
|
| chr13_-_67802549 Show fit | 2.08 |
ENST00000328454.5
ENST00000377865.2 |
protocadherin 9 |
|
| chr17_-_64225508 Show fit | 1.99 |
ENST00000205948.6
|
apolipoprotein H (beta-2-glycoprotein I) |
|
| chr20_-_7921090 Show fit | 1.51 |
ENST00000378789.3
|
hydroxyacid oxidase (glycolate oxidase) 1 |
|
| chr3_-_148939598 Show fit | 1.44 |
ENST00000455472.3
|
ceruloplasmin (ferroxidase) |
|
| chr4_+_165675197 Show fit | 1.33 |
ENST00000515485.1
|
RP11-294O2.2 |
|
| chr7_-_84121858 Show fit | 1.26 |
ENST00000448879.1
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXK1_FOXP2_FOXB1_FOXP3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.9 | GO:0030070 | insulin processing(GO:0030070) |
| 0.0 | 4.4 | GO:0030195 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.3 | 3.6 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 0.2 | 2.6 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.5 | 2.4 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.1 | 2.2 | GO:0090178 | regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) |
| 0.0 | 2.0 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.1 | 1.9 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 1.9 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.5 | 1.8 | GO:0090293 | nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.7 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.2 | 3.1 | GO:0042627 | chylomicron(GO:0042627) |
| 0.4 | 2.2 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.1 | 2.0 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 2.0 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 1.6 | GO:0030478 | actin cap(GO:0030478) |
| 0.3 | 1.5 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.0 | 1.5 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 1.3 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.2 | 1.2 | GO:0097149 | centralspindlin complex(GO:0097149) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.9 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 1.0 | 3.0 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.0 | 2.7 | GO:0005178 | integrin binding(GO:0005178) |
| 0.3 | 2.5 | GO:0038051 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.0 | 2.1 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.1 | 2.0 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.5 | 1.8 | GO:1902122 | chenodeoxycholic acid binding(GO:1902122) |
| 0.2 | 1.8 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.1 | 1.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 1.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.6 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 3.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 2.5 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 2.1 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 2.0 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 1.9 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.6 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.6 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.3 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.2 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 4.0 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 3.6 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 3.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 3.4 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 2.3 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 2.0 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 1.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 1.5 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 1.4 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |