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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for FOXF2_FOXJ1

Z-value: 1.66

Motif logo

Transcription factors associated with FOXF2_FOXJ1

Gene Symbol Gene ID Gene Info
ENSG00000137273.3 forkhead box F2
ENSG00000129654.7 forkhead box J1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXJ1hg19_v2_chr17_-_74137374_74137385-0.851.5e-01Click!
FOXF2hg19_v2_chr6_+_1389989_13900690.841.6e-01Click!

Activity profile of FOXF2_FOXJ1 motif

Sorted Z-values of FOXF2_FOXJ1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_136676707 1.43 ENST00000329582.4
interleukin 20 receptor beta
chr8_-_131028782 1.37 ENST00000519020.1
family with sequence similarity 49, member B
chr3_+_136676851 1.25 ENST00000309741.5
interleukin 20 receptor beta
chr3_-_48956818 1.24 ENST00000408959.2
ariadne homolog 2 opposite strand
chr2_+_175260514 1.19 ENST00000424069.1
ENST00000427038.1
secernin 3
chr4_-_140223614 1.04 ENST00000394223.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr11_-_115375107 1.03 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
cell adhesion molecule 1
chr4_-_140223670 1.00 ENST00000394228.1
ENST00000539387.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr2_+_33661382 1.00 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr10_-_14050522 1.00 ENST00000342409.2
FERM domain containing 4A
chr6_+_21666633 1.00 ENST00000606851.1
cancer susceptibility candidate 15 (non-protein coding)
chr2_+_58655461 0.97 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr16_+_77233294 0.89 ENST00000378644.4
synaptonemal complex central element protein 1-like
chr2_+_12857043 0.86 ENST00000381465.2
tribbles pseudokinase 2
chr5_+_133859996 0.85 ENST00000512386.1
jade family PHD finger 2
chr10_-_375422 0.82 ENST00000434695.2
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr1_+_66796401 0.81 ENST00000528771.1
phosphodiesterase 4B, cAMP-specific
chr11_+_1151573 0.77 ENST00000534821.1
ENST00000356191.2
mucin 5AC, oligomeric mucus/gel-forming
chr8_-_134309823 0.72 ENST00000414097.2
N-myc downstream regulated 1
chr2_-_233877912 0.72 ENST00000264051.3
neuronal guanine nucleotide exchange factor
chr10_+_111985837 0.71 ENST00000393134.1
MAX interactor 1, dimerization protein
chr8_-_134309335 0.71 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
N-myc downstream regulated 1
chr8_+_31496809 0.71 ENST00000518104.1
ENST00000519301.1
neuregulin 1
chr5_-_142065612 0.68 ENST00000360966.5
ENST00000411960.1
fibroblast growth factor 1 (acidic)
chr17_-_6947225 0.67 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
solute carrier family 16, member 11
chr5_-_150460539 0.64 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNFAIP3 interacting protein 1
chr19_+_18496957 0.63 ENST00000252809.3
growth differentiation factor 15
chr11_-_67374177 0.62 ENST00000333139.3
chromosome 11 open reading frame 72
chr13_-_41240717 0.61 ENST00000379561.5
forkhead box O1
chr19_-_58609570 0.61 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
zinc finger and SCAN domain containing 18
chr20_-_43150601 0.59 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr12_-_96389702 0.59 ENST00000552509.1
histidine ammonia-lyase
chr8_-_116673894 0.57 ENST00000395713.2
trichorhinophalangeal syndrome I
chr12_+_28605426 0.56 ENST00000542801.1
coiled-coil domain containing 91
chr9_-_4859260 0.55 ENST00000599351.1
HCG2011465; Uncharacterized protein
chr9_+_78505581 0.55 ENST00000376767.3
ENST00000376752.4
proprotein convertase subtilisin/kexin type 5
chr12_-_96390108 0.53 ENST00000538703.1
ENST00000261208.3
histidine ammonia-lyase
chr5_-_150460914 0.51 ENST00000389378.2
TNFAIP3 interacting protein 1
chr17_+_9745786 0.51 ENST00000304773.5
glucagon-like peptide 2 receptor
chr1_+_43855545 0.49 ENST00000372450.4
ENST00000310739.4
seizure threshold 2 homolog (mouse)
chr17_+_72426891 0.48 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr15_+_63188009 0.47 ENST00000557900.1
RP11-1069G10.2
chr1_+_92545862 0.47 ENST00000370382.3
ENST00000342818.3
BTB (POZ) domain containing 8
chr8_+_11666649 0.47 ENST00000528643.1
ENST00000525777.1
farnesyl-diphosphate farnesyltransferase 1
chr1_+_25664408 0.46 ENST00000374358.4
transmembrane protein 50A
chr8_-_124553437 0.45 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr12_+_40787194 0.45 ENST00000425730.2
ENST00000454784.4
mucin 19, oligomeric
chr1_+_40862501 0.44 ENST00000539317.1
small ArfGAP2
chr6_+_12717892 0.44 ENST00000379350.1
phosphatase and actin regulator 1
chr9_+_112852477 0.44 ENST00000480388.1
A kinase (PRKA) anchor protein 2
chr2_-_102091144 0.44 ENST00000428343.1
RFX family member 8, lacking RFX DNA binding domain
chr18_-_59415987 0.43 ENST00000590199.1
ENST00000590968.1
RP11-879F14.1
chr17_+_26662730 0.43 ENST00000226225.2
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr19_+_50380917 0.41 ENST00000535102.2
TBC1 domain family, member 17
chr12_-_58240470 0.41 ENST00000548823.1
ENST00000398073.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr20_+_44420570 0.41 ENST00000372622.3
deoxynucleotidyltransferase, terminal, interacting protein 1
chr17_+_72427477 0.41 ENST00000342648.5
ENST00000481232.1
G protein-coupled receptor, family C, group 5, member C
chr2_+_175260451 0.41 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
secernin 3
chr19_+_13906250 0.41 ENST00000254323.2
zinc finger, SWIM-type containing 4
chr12_-_116714564 0.41 ENST00000548743.1
mediator complex subunit 13-like
chr15_-_34610962 0.39 ENST00000290209.5
solute carrier family 12 (potassium/chloride transporter), member 6
chr16_+_777739 0.38 ENST00000563792.1
hydroxyacylglutathione hydrolase-like
chr20_-_62582475 0.38 ENST00000369908.5
uridine-cytidine kinase 1-like 1
chr6_+_84563295 0.37 ENST00000369687.1
ripply transcriptional repressor 2
chr19_+_50380682 0.37 ENST00000221543.5
TBC1 domain family, member 17
chr2_+_233527443 0.37 ENST00000410095.1
EF-hand domain family, member D1
chr2_-_165424973 0.37 ENST00000543549.1
growth factor receptor-bound protein 14
chr19_+_7580103 0.36 ENST00000596712.1
zinc finger protein 358
chr2_-_37193606 0.36 ENST00000379213.2
ENST00000263918.4
striatin, calmodulin binding protein
chr5_+_140529630 0.36 ENST00000543635.1
protocadherin beta 6
chr6_-_25830785 0.36 ENST00000468082.1
solute carrier family 17 (organic anion transporter), member 1
chr9_-_130679257 0.36 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr9_-_135819987 0.35 ENST00000298552.3
ENST00000403810.1
tuberous sclerosis 1
chr17_+_67410832 0.35 ENST00000590474.1
mitogen-activated protein kinase kinase 6
chr16_-_86542455 0.34 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FOXF1 adjacent non-coding developmental regulatory RNA
chr18_-_25739260 0.34 ENST00000413878.1
cadherin 2, type 1, N-cadherin (neuronal)
chr19_+_18492973 0.34 ENST00000595973.2
growth differentiation factor 15
chr7_+_134832808 0.34 ENST00000275767.3
transmembrane protein 140
chr1_+_43855560 0.33 ENST00000562955.1
seizure threshold 2 homolog (mouse)
chr8_-_133772794 0.33 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
transmembrane protein 71
chr2_-_39456673 0.33 ENST00000378803.1
ENST00000395035.3
cyclin-dependent kinase-like 4
chr1_+_65730385 0.33 ENST00000263441.7
ENST00000395325.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr2_+_149402989 0.33 ENST00000397424.2
enhancer of polycomb homolog 2 (Drosophila)
chr14_-_36988882 0.32 ENST00000498187.2
NK2 homeobox 1
chr3_-_71179988 0.31 ENST00000491238.1
forkhead box P1
chr4_+_71588372 0.31 ENST00000536664.1
RUN and FYVE domain containing 3
chr2_+_232575168 0.30 ENST00000440384.1
prothymosin, alpha
chr1_-_246357029 0.30 ENST00000391836.2
SET and MYND domain containing 3
chr10_+_70847852 0.30 ENST00000242465.3
serglycin
chr5_-_180076580 0.30 ENST00000502649.1
fms-related tyrosine kinase 4
chr3_+_171561127 0.30 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chr8_+_79428539 0.30 ENST00000352966.5
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr1_-_6420737 0.29 ENST00000541130.1
ENST00000377845.3
acyl-CoA thioesterase 7
chr8_+_52730143 0.29 ENST00000415643.1
Uncharacterized protein
chr4_-_90756769 0.28 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr15_-_59041954 0.28 ENST00000439637.1
ENST00000558004.1
ADAM metallopeptidase domain 10
chr6_+_15401075 0.28 ENST00000541660.1
jumonji, AT rich interactive domain 2
chr5_-_59064458 0.28 ENST00000502575.1
ENST00000507116.1
phosphodiesterase 4D, cAMP-specific
chr1_+_149239529 0.28 ENST00000457216.2
RP11-403I13.4
chr12_+_59989918 0.28 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr12_-_96390063 0.28 ENST00000541929.1
histidine ammonia-lyase
chr4_+_117220016 0.28 ENST00000604093.1
MT-RNR2-like 13 (pseudogene)
chr15_+_74509530 0.27 ENST00000321288.5
coiled-coil domain containing 33
chr19_-_52531600 0.27 ENST00000356322.6
ENST00000270649.6
zinc finger protein 614
chr2_-_240230890 0.27 ENST00000446876.1
histone deacetylase 4
chr12_-_49504449 0.26 ENST00000547675.1
limb development membrane protein 1-like
chr11_+_32154200 0.26 ENST00000525133.1
RP1-65P5.5
chr3_+_98451532 0.26 ENST00000486334.2
ENST00000394162.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr11_-_85397167 0.26 ENST00000316398.3
coiled-coil domain containing 89
chr18_+_77160282 0.26 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr6_-_131321863 0.26 ENST00000528282.1
erythrocyte membrane protein band 4.1-like 2
chr18_+_18943554 0.26 ENST00000580732.2
growth regulation by estrogen in breast cancer-like
chr3_+_157828152 0.25 ENST00000476899.1
arginine/serine-rich coiled-coil 1
chr1_+_15668240 0.25 ENST00000444385.1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr1_-_43855479 0.24 ENST00000290663.6
ENST00000372457.4
mediator complex subunit 8
chr4_+_166794383 0.24 ENST00000061240.2
ENST00000507499.1
tolloid-like 1
chr11_-_119247004 0.24 ENST00000531070.1
ubiquitin specific peptidase 2
chr21_-_46293644 0.24 ENST00000330938.3
pituitary tumor-transforming 1 interacting protein
chr3_-_185826855 0.23 ENST00000306376.5
ets variant 5
chr2_+_179184955 0.23 ENST00000315022.2
oxysterol binding protein-like 6
chr2_+_66918558 0.23 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
chr19_-_50380536 0.23 ENST00000391832.3
ENST00000391834.2
ENST00000344175.5
AKT1 substrate 1 (proline-rich)
chr7_-_25702669 0.22 ENST00000446840.1
AC003090.1
chr1_+_150122034 0.22 ENST00000025469.6
ENST00000369124.4
pleckstrin homology domain containing, family O member 1
chr15_-_40600111 0.22 ENST00000543785.2
ENST00000260402.3
phospholipase C, beta 2
chr14_-_69262916 0.22 ENST00000553375.1
ZFP36 ring finger protein-like 1
chr15_-_76352069 0.22 ENST00000305435.10
ENST00000563910.1
neuregulin 4
chr3_-_71632894 0.22 ENST00000493089.1
forkhead box P1
chr3_+_132316081 0.22 ENST00000249887.2
atypical chemokine receptor 4
chr11_-_34535297 0.22 ENST00000532417.1
E74-like factor 5 (ets domain transcription factor)
chr12_+_50135588 0.22 ENST00000423828.1
ENST00000550445.1
transmembrane BAX inhibitor motif containing 6
chr15_-_34630234 0.21 ENST00000558667.1
ENST00000561120.1
ENST00000559236.1
ENST00000397702.2
solute carrier family 12 (potassium/chloride transporter), member 6
chr11_+_33061336 0.21 ENST00000602733.1
t-complex 11, testis-specific-like 1
chr17_-_29641104 0.21 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr6_+_32121908 0.21 ENST00000375143.2
ENST00000424499.1
palmitoyl-protein thioesterase 2
chr11_-_5526834 0.21 ENST00000380237.1
ENST00000396895.1
ENST00000380252.1
hemoglobin, epsilon 1
hemoglobin, gamma G
chr10_-_4285923 0.21 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr19_-_49016847 0.21 ENST00000598924.1
CTC-273B12.10
chr3_-_157221128 0.20 ENST00000392833.2
ENST00000362010.2
ventricular zone expressed PH domain-containing 1
chr6_+_90192974 0.20 ENST00000520458.1
ankyrin repeat domain 6
chr2_+_86947296 0.20 ENST00000283632.4
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr1_-_149982624 0.20 ENST00000417191.1
ENST00000369135.4
OTU domain containing 7B
chr10_+_75668916 0.20 ENST00000481390.1
plasminogen activator, urokinase
chr3_+_50712672 0.19 ENST00000266037.9
dedicator of cytokinesis 3
chr20_+_44035200 0.19 ENST00000372717.1
ENST00000360981.4
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr7_+_116593292 0.18 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
suppression of tumorigenicity 7
chr15_-_40600026 0.18 ENST00000456256.2
ENST00000557821.1
phospholipase C, beta 2
chr2_+_162272605 0.18 ENST00000389554.3
T-box, brain, 1
chr12_+_50135327 0.17 ENST00000549966.1
ENST00000547832.1
ENST00000547187.1
ENST00000548894.1
ENST00000546914.1
ENST00000552699.1
ENST00000267115.5
transmembrane BAX inhibitor motif containing 6
chr3_+_122513642 0.17 ENST00000261038.5
disrupted in renal carcinoma 2
chr4_-_90757364 0.17 ENST00000508895.1
synuclein, alpha (non A4 component of amyloid precursor)
chr15_-_59041768 0.17 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM metallopeptidase domain 10
chr3_-_164914640 0.17 ENST00000241274.3
SLIT and NTRK-like family, member 3
chr20_+_45338126 0.17 ENST00000359271.2
solute carrier family 2 (facilitated glucose transporter), member 10
chr5_-_180076613 0.16 ENST00000261937.6
ENST00000393347.3
fms-related tyrosine kinase 4
chr6_-_161085291 0.16 ENST00000316300.5
lipoprotein, Lp(a)
chr17_-_26662464 0.16 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
intraflagellar transport 20 homolog (Chlamydomonas)
chr18_-_53068782 0.16 ENST00000569012.1
transcription factor 4
chr10_-_73848086 0.16 ENST00000536168.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr11_-_34535332 0.16 ENST00000257832.2
ENST00000429939.2
E74-like factor 5 (ets domain transcription factor)
chr20_+_44420617 0.16 ENST00000449078.1
ENST00000456939.1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr1_+_185703513 0.15 ENST00000271588.4
ENST00000367492.2
hemicentin 1
chr1_-_43855444 0.15 ENST00000372455.4
mediator complex subunit 8
chr2_-_220264703 0.15 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
aspartyl aminopeptidase
chr13_-_36920420 0.15 ENST00000438666.2
spastic paraplegia 20 (Troyer syndrome)
chr4_-_82393052 0.15 ENST00000335927.7
ENST00000504863.1
ENST00000264400.2
RasGEF domain family, member 1B
chr4_-_186456766 0.15 ENST00000284771.6
PDZ and LIM domain 3
chr12_+_72080253 0.15 ENST00000549735.1
transmembrane protein 19
chr16_-_84178728 0.15 ENST00000562224.1
ENST00000434463.3
ENST00000564998.1
ENST00000219439.4
hydroxysteroid dehydrogenase like 1
chr19_-_49016418 0.15 ENST00000270238.3
lemur tyrosine kinase 3
chr10_+_86184676 0.15 ENST00000543283.1
coiled-coil serine-rich protein 2
chr9_+_113431059 0.15 ENST00000416899.2
muscle, skeletal, receptor tyrosine kinase
chr5_-_131132658 0.14 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr17_+_22022437 0.14 ENST00000540040.1
MT-RNR2-like 1
chr19_-_36523709 0.14 ENST00000592017.1
ENST00000360535.4
CAP-GLY domain containing linker protein 3
chr21_+_34602200 0.14 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
interferon (alpha, beta and omega) receptor 2
chr18_-_53068940 0.14 ENST00000562638.1
transcription factor 4
chr13_-_46756351 0.14 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_114473350 0.14 ENST00000503968.1
homeodomain interacting protein kinase 1
chr3_-_185826718 0.14 ENST00000413301.1
ENST00000421809.1
ets variant 5
chr11_-_108464465 0.14 ENST00000525344.1
exophilin 5
chr17_-_29641084 0.14 ENST00000544462.1
ecotropic viral integration site 2B
chr6_+_32121789 0.13 ENST00000437001.2
ENST00000375137.2
palmitoyl-protein thioesterase 2
chr6_-_43027105 0.13 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr1_+_114472992 0.13 ENST00000514621.1
homeodomain interacting protein kinase 1
chr5_-_19988288 0.13 ENST00000502796.1
ENST00000511273.1
cadherin 18, type 2
chr16_-_28374829 0.13 ENST00000532254.1
nuclear pore complex interacting protein family, member B6
chr7_+_119913688 0.13 ENST00000331113.4
potassium voltage-gated channel, Shal-related subfamily, member 2
chr12_-_21556577 0.13 ENST00000450590.1
ENST00000453443.1
solute carrier organic anion transporter family, member 1A2
chr10_+_115469134 0.13 ENST00000452490.2
caspase 7, apoptosis-related cysteine peptidase
chr1_-_28503693 0.12 ENST00000373857.3
platelet-activating factor receptor
chrX_-_47863348 0.12 ENST00000376943.3
ENST00000396965.1
ENST00000305127.6
zinc finger protein 182
chr8_-_30002179 0.12 ENST00000320542.3
membrane bound O-acyltransferase domain containing 4
chr11_-_16419067 0.12 ENST00000533411.1
SRY (sex determining region Y)-box 6
chr16_+_28763108 0.11 ENST00000357796.3
ENST00000550983.1
nuclear pore complex interacting protein family, member B9
chr6_+_22221010 0.11 ENST00000567753.1
RP11-524C21.2
chr19_+_41725140 0.11 ENST00000359092.3
AXL receptor tyrosine kinase
chr18_-_53068911 0.11 ENST00000537856.3
transcription factor 4
chr19_+_2270283 0.11 ENST00000588673.2
ornithine decarboxylase antizyme 1
chr14_+_23299088 0.11 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
mitochondrial ribosomal protein L52

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXF2_FOXJ1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.3 0.9 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.2 1.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 1.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 1.4 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.8 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.6 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.8 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.6 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.5 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.5 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.5 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.5 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.8 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.7 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 1.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.5 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.6 GO:0009597 detection of virus(GO:0009597)
0.1 0.4 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.3 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.4 GO:0051029 rRNA transport(GO:0051029)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.5 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.7 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.4 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.2 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.4 GO:0044211 CTP salvage(GO:0044211)
0.0 0.2 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.1 GO:0071258 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.0 1.0 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.7 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.9 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.4 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 1.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.5 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.0 0.1 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.0 0.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.0 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.6 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 1.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0015942 formate metabolic process(GO:0015942)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.4 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.0 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.3 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0035864 response to potassium ion(GO:0035864)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0070701 mucus layer(GO:0070701)
0.1 0.8 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.5 2.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 0.5 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.1 0.8 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.5 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 2.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.6 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 1.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.7 GO:0044548 fibroblast growth factor receptor binding(GO:0005104) S100 protein binding(GO:0044548)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 1.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors