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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for FOXD3_FOXI1_FOXF1
Z-value: 1.10
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Transcription factors associated with FOXD3_FOXI1_FOXF1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXD3 | hg19_v2_chr1_+_63788730_63788730 | 0.87 | 1.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_40841410 Show fit | 1.03 |
ENST00000381677.3
|
caspase recruitment domain family, member 6 |
|
| chr9_+_78505581 Show fit | 1.03 |
ENST00000376767.3
ENST00000376752.4 |
proprotein convertase subtilisin/kexin type 5 |
|
| chr2_+_232575168 Show fit | 0.93 |
ENST00000440384.1
|
prothymosin, alpha |
|
| chr1_+_207277632 Show fit | 0.86 |
ENST00000421786.1
|
complement component 4 binding protein, alpha |
|
| chr8_+_86999516 Show fit | 0.76 |
ENST00000521564.1
|
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 |
|
| chr3_-_148939598 Show fit | 0.72 |
ENST00000455472.3
|
ceruloplasmin (ferroxidase) |
|
| chr15_-_76352069 Show fit | 0.68 |
ENST00000305435.10
ENST00000563910.1 |
neuregulin 4 |
|
| chr8_+_52730143 Show fit | 0.64 |
ENST00000415643.1
|
Uncharacterized protein |
|
| chr17_+_57408994 Show fit | 0.63 |
ENST00000312655.4
|
yippee-like 2 (Drosophila) |
|
| chr6_-_134861089 Show fit | 0.59 |
ENST00000606039.1
|
RP11-557H15.4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXD3_FOXI1_FOXF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.1 | 0.9 | GO:0032455 | nerve growth factor processing(GO:0032455) |
| 0.0 | 0.9 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.8 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 0.8 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.1 | 0.5 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.1 | 0.5 | GO:0030450 | regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) |
| 0.0 | 0.5 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.0 | 0.5 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.0 | 0.5 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.0 | 0.8 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.0 | 0.8 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.8 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.6 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.0 | 0.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 0.4 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.1 | 0.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.0 | 0.4 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.0 | 0.4 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.1 | 0.9 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 0.0 | 0.9 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 0.8 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 0.8 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 0.5 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.0 | 0.5 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 0.4 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.1 | 0.4 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.0 | 0.4 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.6 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 0.5 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.4 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.3 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 0.1 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.0 | 0.8 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.6 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.5 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.0 | 0.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 0.4 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.4 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.4 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.4 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |