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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
Z-value: 1.00
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Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSG00000251493.2 | forkhead box D1 | |
| ENSG00000150907.6 | forkhead box O1 | |
| ENSG00000204060.4 | forkhead box O6 | |
| ENSG00000176165.7 | forkhead box G1 | |
| ENSG00000114861.14 | forkhead box P1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXP1 | hg19_v2_chr3_-_71179988_71180085 | 0.98 | 1.7e-02 | Click! |
| FOXD1 | hg19_v2_chr5_-_72744336_72744359 | 0.95 | 5.4e-02 | Click! |
| FOXO6 | hg19_v2_chr1_+_41827594_41827594 | -0.56 | 4.4e-01 | Click! |
| FOXG1 | hg19_v2_chr14_+_29236269_29236287 | -0.53 | 4.7e-01 | Click! |
| FOXO1 | hg19_v2_chr13_-_41240717_41240735 | -0.30 | 7.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_+_84563295 Show fit | 1.53 |
ENST00000369687.1
|
ripply transcriptional repressor 2 |
|
| chr2_+_66918558 Show fit | 1.51 |
ENST00000435389.1
ENST00000428590.1 ENST00000412944.1 |
AC007392.3 |
|
| chr7_+_134832808 Show fit | 1.26 |
ENST00000275767.3
|
transmembrane protein 140 |
|
| chr2_-_191878681 Show fit | 1.11 |
ENST00000409465.1
|
signal transducer and activator of transcription 1, 91kDa |
|
| chr1_+_116654376 Show fit | 1.08 |
ENST00000369500.3
|
mab-21-like 3 (C. elegans) |
|
| chr17_+_26662679 Show fit | 1.02 |
ENST00000578158.1
|
tumor necrosis factor, alpha-induced protein 1 (endothelial) |
|
| chr12_-_116714564 Show fit | 0.94 |
ENST00000548743.1
|
mediator complex subunit 13-like |
|
| chr1_-_161337662 Show fit | 0.91 |
ENST00000367974.1
|
chromosome 1 open reading frame 192 |
|
| chr18_-_2982869 Show fit | 0.91 |
ENST00000584915.1
|
lipin 2 |
|
| chr22_-_31688431 Show fit | 0.87 |
ENST00000402249.3
ENST00000443175.1 ENST00000215912.5 ENST00000441972.1 |
phosphoinositide-3-kinase interacting protein 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.8 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
| 0.3 | 1.5 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.3 | 1.5 | GO:0072619 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.0 | 1.5 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.0 | 1.4 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
| 0.3 | 1.3 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.3 | 1.3 | GO:0052250 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.3 | 1.1 | GO:0072308 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) |
| 0.1 | 1.1 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.0 | 1.1 | GO:0032060 | bleb assembly(GO:0032060) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 1.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 1.2 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 1.1 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.9 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.8 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 0.7 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 0.6 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.6 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 0.6 | GO:0030018 | Z disc(GO:0030018) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.5 | 1.5 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.1 | 1.5 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 1.3 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.0 | 1.2 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.0 | 1.2 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 1.1 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.2 | 0.9 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.9 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.0 | 0.9 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 1.1 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.0 | 1.0 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 1.0 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 0.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.8 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 0.7 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 0.6 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.5 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 0.4 | PID ATM PATHWAY | ATM pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 1.1 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.9 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 0.8 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.8 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.7 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.0 | 0.7 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.7 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 0.6 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |