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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 1.00

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Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Gene Symbol Gene ID Gene Info
FOXD1
ENSG00000251493.2 forkhead box D1
FOXO1
ENSG00000150907.6 forkhead box O1
FOXO6
ENSG00000204060.4 forkhead box O6
FOXG1
ENSG00000176165.7 forkhead box G1
FOXP1
ENSG00000114861.14 forkhead box P1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXP1hg19_v2_chr3_-_71179988_711800850.981.7e-02Click!
FOXD1hg19_v2_chr5_-_72744336_727443590.955.4e-02Click!
FOXO6hg19_v2_chr1_+_41827594_41827594-0.564.4e-01Click!
FOXG1hg19_v2_chr14_+_29236269_29236287-0.534.7e-01Click!
FOXO1hg19_v2_chr13_-_41240717_41240735-0.307.0e-01Click!

Activity profile of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Sorted Z-values of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_84563295 1.53 ENST00000369687.1
RIPPLY2
ripply transcriptional repressor 2
chr2_+_66918558 1.51 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr7_+_134832808 1.26 ENST00000275767.3
TMEM140
transmembrane protein 140
chr2_-_191878681 1.11 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_+_116654376 1.08 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr17_+_26662679 1.02 ENST00000578158.1
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr12_-_116714564 0.94 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr1_-_161337662 0.91 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr18_-_2982869 0.91 ENST00000584915.1
LPIN2
lipin 2
chr22_-_31688431 0.87 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr10_+_43932282 0.81 ENST00000431662.1
ENST00000315429.6
ZNF487
zinc finger protein 487
chr2_+_149402989 0.79 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr10_+_75668916 0.79 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr4_-_141075330 0.77 ENST00000509479.2
MAML3
mastermind-like 3 (Drosophila)
chr8_-_29208183 0.76 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr5_-_150460539 0.74 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr7_-_112579673 0.74 ENST00000432572.1
C7orf60
chromosome 7 open reading frame 60
chr3_-_185826718 0.74 ENST00000413301.1
ENST00000421809.1
ETV5
ets variant 5
chr3_-_71179988 0.73 ENST00000491238.1
FOXP1
forkhead box P1
chr12_+_13349711 0.73 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr6_+_26020672 0.73 ENST00000357647.3
HIST1H3A
histone cluster 1, H3a
chr13_-_46716969 0.69 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_88875628 0.67 ENST00000551417.1
CNR1
cannabinoid receptor 1 (brain)
chr5_+_133451254 0.66 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr17_+_72427477 0.63 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr8_+_95908041 0.63 ENST00000396113.1
ENST00000519136.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr8_+_39972170 0.62 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr17_+_65373531 0.61 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr7_-_99698338 0.61 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr2_+_27665232 0.60 ENST00000543753.1
ENST00000288873.3
KRTCAP3
keratinocyte associated protein 3
chr22_-_31688381 0.59 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr3_-_185826855 0.58 ENST00000306376.5
ETV5
ets variant 5
chr15_+_96897466 0.58 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3
RP11-522B15.3
chr5_-_137674000 0.57 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr17_+_72426891 0.56 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr18_-_59415987 0.56 ENST00000590199.1
ENST00000590968.1
RP11-879F14.1
RP11-879F14.1
chr1_+_66796401 0.55 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr16_-_84150392 0.55 ENST00000570012.1
MBTPS1
membrane-bound transcription factor peptidase, site 1
chr2_-_165424973 0.53 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr5_-_150460914 0.52 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr1_+_92545862 0.51 ENST00000370382.3
ENST00000342818.3
BTBD8
BTB (POZ) domain containing 8
chr17_+_37821593 0.50 ENST00000578283.1
TCAP
titin-cap
chr2_+_33661382 0.50 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_+_13349650 0.49 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr16_-_57832004 0.49 ENST00000562503.1
KIFC3
kinesin family member C3
chr1_-_12677714 0.49 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr1_-_27816556 0.49 ENST00000536657.1
WASF2
WAS protein family, member 2
chr17_+_65374075 0.48 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr7_+_129007964 0.48 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr2_+_175260514 0.48 ENST00000424069.1
ENST00000427038.1
SCRN3
secernin 3
chr10_+_97759848 0.47 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr2_+_149402553 0.47 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr1_+_209878182 0.47 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chrX_+_135251835 0.47 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr3_-_117716418 0.46 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr11_+_10476851 0.45 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr9_-_20382446 0.44 ENST00000380321.1
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_+_152178320 0.44 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr9_-_84303269 0.44 ENST00000418319.1
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chrX_+_135251783 0.44 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr17_+_41561317 0.43 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr2_+_27665289 0.43 ENST00000407293.1
KRTCAP3
keratinocyte associated protein 3
chr2_-_160472952 0.41 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr11_+_117049910 0.41 ENST00000431081.2
ENST00000524842.1
SIDT2
SID1 transmembrane family, member 2
chr2_-_176033066 0.41 ENST00000437522.1
ATF2
activating transcription factor 2
chr19_+_41725140 0.41 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr20_-_45984401 0.40 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr11_-_115375107 0.39 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chrX_+_135252050 0.39 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr14_+_24584508 0.39 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11
DDB1 and CUL4 associated factor 11
chr12_+_54378849 0.39 ENST00000515593.1
HOXC10
homeobox C10
chr5_-_16742330 0.39 ENST00000505695.1
ENST00000427430.2
MYO10
myosin X
chr1_+_3541543 0.38 ENST00000378344.2
ENST00000344579.5
TPRG1L
tumor protein p63 regulated 1-like
chr8_-_119124045 0.38 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr2_-_27434611 0.38 ENST00000408041.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr12_+_48499252 0.38 ENST00000549003.1
ENST00000550924.1
PFKM
phosphofructokinase, muscle
chr3_-_48956818 0.37 ENST00000408959.2
ARIH2OS
ariadne homolog 2 opposite strand
chr19_-_45909585 0.36 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr2_+_198380763 0.36 ENST00000448447.2
ENST00000409360.1
MOB4
MOB family member 4, phocein
chr17_+_26662597 0.36 ENST00000544907.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr2_-_233877912 0.36 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chr11_+_31833939 0.35 ENST00000530348.1
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr6_-_30043539 0.35 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr3_-_178865747 0.34 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr8_+_126442563 0.34 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr8_+_31496809 0.34 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr19_+_13906250 0.34 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr20_-_43150601 0.33 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
SERINC3
serine incorporator 3
chr3_+_148447887 0.33 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr10_+_31610064 0.33 ENST00000446923.2
ENST00000559476.1
ZEB1
zinc finger E-box binding homeobox 1
chr11_+_3968573 0.33 ENST00000532990.1
STIM1
stromal interaction molecule 1
chr5_-_115872142 0.32 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr7_-_25702669 0.31 ENST00000446840.1
AC003090.1
AC003090.1
chr8_+_97773202 0.31 ENST00000519484.1
CPQ
carboxypeptidase Q
chr6_+_33168189 0.31 ENST00000444757.1
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr1_-_153931052 0.31 ENST00000368630.3
ENST00000368633.1
CRTC2
CREB regulated transcription coactivator 2
chr16_-_57831676 0.31 ENST00000465878.2
ENST00000539578.1
ENST00000561524.1
KIFC3
kinesin family member C3
chr17_-_1418972 0.30 ENST00000571274.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr14_-_36988882 0.30 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr16_+_57680840 0.30 ENST00000563862.1
ENST00000564722.1
ENST00000569158.1
GPR56
G protein-coupled receptor 56
chr14_-_37051798 0.30 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr2_+_12857015 0.30 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr3_-_107777208 0.30 ENST00000398258.3
CD47
CD47 molecule
chr10_+_99400443 0.30 ENST00000370631.3
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr1_+_43855545 0.29 ENST00000372450.4
ENST00000310739.4
SZT2
seizure threshold 2 homolog (mouse)
chr16_-_57831914 0.29 ENST00000421376.2
KIFC3
kinesin family member C3
chr2_-_74007095 0.28 ENST00000452812.1
DUSP11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr14_+_23067166 0.28 ENST00000216327.6
ENST00000542041.1
ABHD4
abhydrolase domain containing 4
chr6_-_134638767 0.28 ENST00000524929.1
SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_9745786 0.28 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr1_-_27816641 0.28 ENST00000430629.2
WASF2
WAS protein family, member 2
chr7_+_134576317 0.27 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr2_-_152146385 0.27 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr8_+_97773457 0.27 ENST00000521142.1
CPQ
carboxypeptidase Q
chr9_-_135819987 0.27 ENST00000298552.3
ENST00000403810.1
TSC1
tuberous sclerosis 1
chr16_+_86612112 0.27 ENST00000320241.3
FOXL1
forkhead box L1
chr1_+_164528437 0.26 ENST00000485769.1
PBX1
pre-B-cell leukemia homeobox 1
chr4_-_41884620 0.26 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr9_+_131904233 0.26 ENST00000432651.1
ENST00000435132.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr1_-_28503693 0.26 ENST00000373857.3
PTAFR
platelet-activating factor receptor
chr12_+_120740119 0.26 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr2_-_27434635 0.26 ENST00000401463.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr9_-_16253112 0.26 ENST00000380683.1
C9orf92
chromosome 9 open reading frame 92
chr1_+_84630574 0.26 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_69215699 0.25 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr15_+_80351910 0.25 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr9_+_131903916 0.25 ENST00000419582.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr18_-_53303123 0.25 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr1_+_20512568 0.25 ENST00000375099.3
UBXN10
UBX domain protein 10
chr10_-_101380121 0.25 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr3_-_71179699 0.25 ENST00000497355.1
FOXP1
forkhead box P1
chr3_-_71294304 0.24 ENST00000498215.1
FOXP1
forkhead box P1
chr16_+_57679859 0.24 ENST00000569494.1
ENST00000566169.1
GPR56
G protein-coupled receptor 56
chr15_-_83240507 0.24 ENST00000564522.1
ENST00000398592.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr2_-_190927447 0.24 ENST00000260950.4
MSTN
myostatin
chrX_-_106146547 0.24 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr3_+_107241783 0.24 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr6_-_42418999 0.24 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chrX_-_54070607 0.24 ENST00000338154.6
ENST00000338946.6
PHF8
PHD finger protein 8
chr1_+_179851893 0.24 ENST00000531630.2
TOR1AIP1
torsin A interacting protein 1
chr15_+_80733570 0.23 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr11_-_34535297 0.23 ENST00000532417.1
ELF5
E74-like factor 5 (ets domain transcription factor)
chr6_-_127780510 0.22 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr16_+_57680811 0.22 ENST00000569101.1
GPR56
G protein-coupled receptor 56
chr6_+_30853002 0.22 ENST00000421124.2
ENST00000512725.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr13_-_46756351 0.22 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr9_+_131904295 0.22 ENST00000434095.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr2_+_12857043 0.22 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr7_-_27219849 0.22 ENST00000396344.4
HOXA10
homeobox A10
chr16_-_69418553 0.22 ENST00000569542.2
TERF2
telomeric repeat binding factor 2
chr6_+_15401075 0.22 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr3_+_171561127 0.22 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr8_-_133772794 0.22 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
TMEM71
transmembrane protein 71
chr20_+_44421137 0.22 ENST00000415790.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr6_-_33168391 0.21 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr16_+_57679945 0.21 ENST00000568157.1
GPR56
G protein-coupled receptor 56
chr8_+_81397846 0.21 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr6_+_32121908 0.21 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr19_+_41725088 0.21 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chrX_-_19688475 0.21 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chrX_-_15619076 0.21 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr1_-_168106536 0.21 ENST00000537209.1
ENST00000361697.2
ENST00000546300.1
ENST00000367835.1
GPR161
G protein-coupled receptor 161
chr11_+_117049854 0.21 ENST00000278951.7
SIDT2
SID1 transmembrane family, member 2
chr11_+_63606477 0.20 ENST00000508192.1
ENST00000361128.5
MARK2
MAP/microtubule affinity-regulating kinase 2
chr2_-_68547061 0.20 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr20_+_44035200 0.20 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_+_46402297 0.20 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chrX_-_68385354 0.20 ENST00000361478.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr2_-_26205550 0.20 ENST00000405914.1
KIF3C
kinesin family member 3C
chr12_-_6665200 0.20 ENST00000336604.4
ENST00000396840.2
ENST00000356896.4
IFFO1
intermediate filament family orphan 1
chr3_+_137717571 0.20 ENST00000343735.4
CLDN18
claudin 18
chr16_-_69418649 0.20 ENST00000566257.1
TERF2
telomeric repeat binding factor 2
chr5_+_121465207 0.20 ENST00000296600.4
ZNF474
zinc finger protein 474
chr20_+_56964169 0.20 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr9_-_107690420 0.20 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr2_+_70142232 0.20 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr3_-_71632894 0.19 ENST00000493089.1
FOXP1
forkhead box P1
chr10_-_13570533 0.19 ENST00000396900.2
ENST00000396898.2
BEND7
BEN domain containing 7
chr22_-_45404819 0.19 ENST00000447824.3
ENST00000404079.2
ENST00000420689.1
ENST00000403565.1
PHF21B
PHD finger protein 21B
chr2_-_26205340 0.19 ENST00000264712.3
KIF3C
kinesin family member 3C
chr11_+_46402482 0.19 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr17_+_74372662 0.19 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr17_-_39183452 0.19 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr13_+_50589390 0.19 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chr4_+_86396321 0.19 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr3_-_141868357 0.18 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr16_-_67597789 0.18 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr16_-_87729753 0.18 ENST00000538868.1
AC010536.1
Uncharacterized protein; cDNA FLJ45526 fis, clone BRTHA2027227
chr13_-_30683005 0.18 ENST00000413591.1
ENST00000432770.1
LINC00365
long intergenic non-protein coding RNA 365
chr19_+_13134772 0.18 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr8_-_134309823 0.18 ENST00000414097.2
NDRG1
N-myc downstream regulated 1
chr17_+_38333263 0.18 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr1_-_94079648 0.18 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr12_-_12714006 0.18 ENST00000541207.1
DUSP16
dual specificity phosphatase 16
chr10_-_46089939 0.18 ENST00000453980.3
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr17_-_61776522 0.18 ENST00000582055.1
LIMD2
LIM domain containing 2
chr8_-_134309335 0.18 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr12_+_50135351 0.18 ENST00000549445.1
ENST00000550951.1
ENST00000549385.1
ENST00000548713.1
ENST00000548201.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr17_+_72428218 0.18 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr15_-_34629922 0.18 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.3 1.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 1.3 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 1.5 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 0.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.5 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.2 0.5 GO:0035995 detection of muscle stretch(GO:0035995)
0.2 1.8 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.7 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.8 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1 0.3 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.7 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 1.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.4 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.6 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 0.1 GO:0014874 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to stimulus involved in regulation of muscle adaptation(GO:0014874) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.3 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.1 0.2 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
0.1 0.4 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.3 GO:0043315 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1 0.3 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.5 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:0030421 defecation(GO:0030421)
0.1 0.5 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.4 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.2 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.3 GO:0051029 rRNA transport(GO:0051029)
0.1 0.3 GO:0018032 protein amidation(GO:0018032)
0.1 0.2 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.3 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.3 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0009597 detection of virus(GO:0009597)
0.0 0.0 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.0 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.3 GO:0045354 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.2 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 1.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.6 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0002035 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.3 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.2 GO:1904499 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 1.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.6 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.3 GO:2001205 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.0 0.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0002725 negative regulation of T cell cytokine production(GO:0002725) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 1.4 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.1 GO:0060414 optic placode formation involved in camera-type eye formation(GO:0046619) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582) sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0033210 leptin-mediated signaling pathway(GO:0033210) adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0070343 white fat cell proliferation(GO:0070343) positive regulation of fat cell proliferation(GO:0070346) regulation of white fat cell proliferation(GO:0070350)
0.0 0.7 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 1.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.0 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.0 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.0 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.2 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.0 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.3 GO:0060065 uterus development(GO:0060065)
0.0 0.4 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.2 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 1.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0033643 host cell part(GO:0033643)
0.0 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.6 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.0 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.5 GO:0051373 FATZ binding(GO:0051373)
0.2 0.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.7 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.6 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 1.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.3 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.3 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.6 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 1.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.2 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.1 0.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0050659 chondroitin 4-sulfotransferase activity(GO:0047756) N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 1.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.0 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.0 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0001083 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening