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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for FOSL2_SMARCC1

Z-value: 1.11

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Transcription factors associated with FOSL2_SMARCC1

Gene Symbol Gene ID Gene Info
FOSL2
ENSG00000075426.7 FOS like 2, AP-1 transcription factor subunit
SMARCC1
ENSG00000173473.6 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL2hg19_v2_chr2_+_28615669_286157330.811.9e-01Click!
SMARCC1hg19_v2_chr3_-_47823298_47823423-0.376.3e-01Click!

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102668879 1.75 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr5_-_176923803 1.52 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr17_+_7482785 1.48 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68
CD68 molecule
chr5_-_176923846 1.35 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr11_+_57308979 1.34 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr19_-_36019123 1.07 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr3_-_48601206 0.98 ENST00000273610.3
UCN2
urocortin 2
chr6_+_47666275 0.94 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr7_+_116312411 0.93 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr3_+_48507210 0.91 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr18_+_21452964 0.83 ENST00000587184.1
LAMA3
laminin, alpha 3
chr2_+_169926047 0.82 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr19_-_44174330 0.82 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr18_+_61637159 0.81 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
SERPINB8
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr14_+_77425972 0.81 ENST00000553613.1
RP11-7F17.7
RP11-7F17.7
chr18_+_21452804 0.81 ENST00000269217.6
LAMA3
laminin, alpha 3
chr5_+_150020240 0.80 ENST00000519664.1
SYNPO
synaptopodin
chr3_+_48507621 0.80 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr19_-_44174305 0.76 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr1_+_150480551 0.72 ENST00000369049.4
ENST00000369047.4
ECM1
extracellular matrix protein 1
chr1_-_153521714 0.72 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr12_+_48152774 0.69 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr19_-_55881741 0.68 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11
interleukin 11
chr22_+_22723969 0.66 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr7_-_130597935 0.64 ENST00000447307.1
ENST00000418546.1
MIR29B1
microRNA 29a
chr1_+_183155373 0.63 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr1_+_150480576 0.61 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr15_+_41245160 0.61 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr20_-_44455976 0.60 ENST00000372555.3
TNNC2
troponin C type 2 (fast)
chr7_+_143078379 0.60 ENST00000449630.1
ENST00000457235.1
ZYX
zyxin
chr11_-_65150103 0.59 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45
solute carrier family 25, member 45
chr3_-_48632593 0.59 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr17_-_39769005 0.59 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr12_+_52695617 0.59 ENST00000293525.5
KRT86
keratin 86
chr4_+_74606223 0.57 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr11_-_62323702 0.55 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr15_+_89182178 0.55 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 0.55 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr19_+_39279838 0.54 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr4_-_69083720 0.53 ENST00000432593.3
TMPRSS11BNL
TMPRSS11B N-terminal like
chr3_+_11178779 0.50 ENST00000438284.2
HRH1
histamine receptor H1
chr15_+_89181974 0.50 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr19_-_47128294 0.49 ENST00000596260.1
ENST00000597185.1
ENST00000598865.1
ENST00000594275.1
ENST00000291294.2
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr1_+_201159914 0.49 ENST00000335211.4
ENST00000451870.2
ENST00000295591.8
IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr10_-_6019552 0.49 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
IL15RA
interleukin 15 receptor, alpha
chr7_-_33080506 0.48 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr12_+_56732658 0.46 ENST00000228534.4
IL23A
interleukin 23, alpha subunit p19
chr1_-_153521597 0.45 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr19_-_36004543 0.45 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chr19_+_4229495 0.44 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr17_-_70417365 0.44 ENST00000580948.1
LINC00511
long intergenic non-protein coding RNA 511
chr15_-_74504560 0.44 ENST00000449139.2
STRA6
stimulated by retinoic acid 6
chr17_+_73717407 0.43 ENST00000579662.1
ITGB4
integrin, beta 4
chr1_-_11918988 0.43 ENST00000376468.3
NPPB
natriuretic peptide B
chr8_+_142264664 0.43 ENST00000518520.1
RP11-10J21.3
Uncharacterized protein
chr17_+_37030127 0.43 ENST00000419929.1
LASP1
LIM and SH3 protein 1
chr17_+_79071365 0.42 ENST00000576756.1
BAIAP2
BAI1-associated protein 2
chr12_+_10365082 0.42 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr12_+_7023735 0.42 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2
enolase 2 (gamma, neuronal)
chr10_+_104155450 0.42 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr16_+_15596123 0.42 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr1_-_223853348 0.41 ENST00000366872.5
CAPN8
calpain 8
chr9_-_112179990 0.41 ENST00000394827.3
PTPN3
protein tyrosine phosphatase, non-receptor type 3
chr19_-_39264072 0.40 ENST00000599035.1
ENST00000378626.4
LGALS7
lectin, galactoside-binding, soluble, 7
chr17_+_73717516 0.40 ENST00000200181.3
ENST00000339591.3
ITGB4
integrin, beta 4
chr7_+_22766766 0.40 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr6_-_35888858 0.40 ENST00000507909.1
SRPK1
SRSF protein kinase 1
chr12_+_7023491 0.39 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr18_+_34124507 0.39 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr11_-_66103932 0.39 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr5_-_176924562 0.39 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
PDLIM7
PDZ and LIM domain 7 (enigma)
chr8_-_110988070 0.38 ENST00000524391.1
KCNV1
potassium channel, subfamily V, member 1
chr15_+_67458357 0.38 ENST00000537194.2
SMAD3
SMAD family member 3
chr19_+_7953417 0.38 ENST00000600345.1
ENST00000598224.1
LRRC8E
leucine rich repeat containing 8 family, member E
chr17_+_73717551 0.38 ENST00000450894.3
ITGB4
integrin, beta 4
chr5_+_150020214 0.38 ENST00000307662.4
SYNPO
synaptopodin
chr19_-_48018203 0.38 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr11_+_10476851 0.37 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr21_-_35340759 0.37 ENST00000607953.1
AP000569.9
AP000569.9
chr10_-_6019984 0.36 ENST00000525219.2
IL15RA
interleukin 15 receptor, alpha
chr6_+_83072923 0.36 ENST00000535040.1
TPBG
trophoblast glycoprotein
chrX_+_12993202 0.36 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr15_+_67420441 0.36 ENST00000558894.1
SMAD3
SMAD family member 3
chr7_+_55177416 0.36 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr17_+_74381343 0.35 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr11_-_2950642 0.35 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr6_+_31082603 0.34 ENST00000259881.9
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr11_-_65149422 0.33 ENST00000526432.1
ENST00000527174.1
SLC25A45
solute carrier family 25, member 45
chr5_+_135394840 0.33 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr7_-_150721570 0.33 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B
autophagy related 9B
chr17_+_58018269 0.33 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr19_-_40931891 0.33 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr1_-_153935791 0.33 ENST00000429040.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr3_+_183894737 0.32 ENST00000432591.1
ENST00000431779.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr11_+_66742742 0.32 ENST00000308963.4
C11orf86
chromosome 11 open reading frame 86
chr10_-_6019455 0.32 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
IL15RA
interleukin 15 receptor, alpha
chr17_-_73775839 0.31 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr1_+_17634689 0.31 ENST00000375453.1
ENST00000375448.4
PADI4
peptidyl arginine deiminase, type IV
chr17_-_73781567 0.31 ENST00000586607.1
H3F3B
H3 histone, family 3B (H3.3B)
chr12_-_10282836 0.30 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr10_-_90611566 0.29 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr20_+_35504522 0.29 ENST00000602922.1
ENST00000217320.3
TLDC2
TBC/LysM-associated domain containing 2
chr7_+_129932974 0.29 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4
carboxypeptidase A4
chr22_+_22673051 0.29 ENST00000390289.2
IGLV5-52
immunoglobulin lambda variable 5-52
chr4_+_108746282 0.29 ENST00000503862.1
SGMS2
sphingomyelin synthase 2
chr7_+_48128194 0.28 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1
uridine phosphorylase 1
chr8_-_123706338 0.27 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr6_-_169563013 0.27 ENST00000439703.1
RP11-417E7.1
RP11-417E7.1
chr17_-_8021710 0.27 ENST00000380149.1
ENST00000448843.2
ALOXE3
arachidonate lipoxygenase 3
chr17_+_30771279 0.27 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr2_+_169923577 0.27 ENST00000432060.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr17_+_7255208 0.27 ENST00000333751.3
KCTD11
potassium channel tetramerization domain containing 11
chr3_-_98241598 0.27 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
CLDND1
claudin domain containing 1
chr1_+_161494036 0.27 ENST00000309758.4
HSPA6
heat shock 70kDa protein 6 (HSP70B')
chr1_-_27816641 0.27 ENST00000430629.2
WASF2
WAS protein family, member 2
chr9_+_127023704 0.26 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr6_+_31916733 0.26 ENST00000483004.1
CFB
complement factor B
chr10_+_75668916 0.26 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr15_+_67418047 0.26 ENST00000540846.2
SMAD3
SMAD family member 3
chr3_-_196065374 0.26 ENST00000454715.1
TM4SF19
transmembrane 4 L six family member 19
chr15_-_80263506 0.26 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr1_-_153935738 0.26 ENST00000417348.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr8_+_126442563 0.26 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr1_+_6511651 0.26 ENST00000434576.1
ESPN
espin
chr17_+_65375082 0.26 ENST00000584471.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr3_+_183894566 0.25 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr3_+_36421971 0.25 ENST00000457375.2
ENST00000434649.1
STAC
SH3 and cysteine rich domain
chr7_+_48128316 0.25 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr19_+_10400615 0.25 ENST00000221980.4
ICAM5
intercellular adhesion molecule 5, telencephalin
chr15_-_44486632 0.25 ENST00000484674.1
FRMD5
FERM domain containing 5
chr19_+_850985 0.25 ENST00000590230.1
ELANE
elastase, neutrophil expressed
chr13_-_36429763 0.24 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr12_-_118490217 0.24 ENST00000542304.1
WSB2
WD repeat and SOCS box containing 2
chr6_+_32121218 0.24 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr14_+_55221541 0.24 ENST00000555192.1
SAMD4A
sterile alpha motif domain containing 4A
chr12_+_13349650 0.24 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chrX_+_135252050 0.24 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr12_-_719573 0.24 ENST00000397265.3
NINJ2
ninjurin 2
chr5_-_134914673 0.24 ENST00000512158.1
CXCL14
chemokine (C-X-C motif) ligand 14
chr7_+_123488124 0.24 ENST00000476325.1
HYAL4
hyaluronoglucosaminidase 4
chr3_-_48598547 0.23 ENST00000536104.1
ENST00000452531.1
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr12_+_13349711 0.23 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr12_-_120805872 0.23 ENST00000546985.1
MSI1
musashi RNA-binding protein 1
chr1_+_901847 0.23 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
PLEKHN1
pleckstrin homology domain containing, family N member 1
chr1_-_113247543 0.23 ENST00000414971.1
ENST00000534717.1
RHOC
ras homolog family member C
chr11_+_101983176 0.23 ENST00000524575.1
YAP1
Yes-associated protein 1
chr15_-_74504597 0.23 ENST00000416286.3
STRA6
stimulated by retinoic acid 6
chr2_+_87754989 0.23 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr16_-_4664860 0.23 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr12_-_56236711 0.22 ENST00000409200.3
MMP19
matrix metallopeptidase 19
chr3_+_148447887 0.22 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr3_+_191046810 0.22 ENST00000392455.3
ENST00000392456.3
CCDC50
coiled-coil domain containing 50
chr7_+_128095945 0.22 ENST00000257696.4
HILPDA
hypoxia inducible lipid droplet-associated
chr16_-_30997533 0.22 ENST00000602217.1
AC135048.1
Uncharacterized protein
chr18_+_61442629 0.22 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chrX_+_135251783 0.21 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr7_+_128095900 0.21 ENST00000435296.2
HILPDA
hypoxia inducible lipid droplet-associated
chr1_-_45272951 0.21 ENST00000372200.1
TCTEX1D4
Tctex1 domain containing 4
chr15_-_72521017 0.21 ENST00000561609.1
PKM
pyruvate kinase, muscle
chr1_+_223889310 0.21 ENST00000434648.1
CAPN2
calpain 2, (m/II) large subunit
chr1_+_36554470 0.21 ENST00000373178.4
ADPRHL2
ADP-ribosylhydrolase like 2
chr20_+_43343886 0.21 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr10_-_22292675 0.21 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr14_+_69726656 0.21 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr11_+_35684288 0.21 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr17_+_9745786 0.20 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr7_+_871559 0.20 ENST00000421580.1
SUN1
Sad1 and UNC84 domain containing 1
chr8_+_22844995 0.20 ENST00000524077.1
RHOBTB2
Rho-related BTB domain containing 2
chr17_+_80193644 0.20 ENST00000582946.1
SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
chr11_-_5706239 0.20 ENST00000396847.3
ENST00000419850.1
ENST00000380034.3
ENST00000396855.3
ENST00000305836.5
ENST00000396853.4
TRIM5
tripartite motif containing 5
chr1_-_1763721 0.20 ENST00000437146.1
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr16_+_30751953 0.20 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr16_-_4665023 0.20 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr12_+_9144626 0.20 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr11_-_66104237 0.20 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr5_-_75919253 0.20 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr14_+_103800513 0.20 ENST00000560338.1
ENST00000560763.1
ENST00000558316.1
ENST00000558265.1
EIF5
eukaryotic translation initiation factor 5
chr17_+_79650962 0.20 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr18_+_1099004 0.20 ENST00000581556.1
RP11-78F17.1
RP11-78F17.1
chr10_-_73611046 0.20 ENST00000394934.1
ENST00000394936.3
PSAP
prosaposin
chr7_+_28448995 0.20 ENST00000424599.1
CREB5
cAMP responsive element binding protein 5
chr15_+_91416092 0.19 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr3_+_184016986 0.19 ENST00000417952.1
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chrX_+_135251835 0.19 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr16_-_1429010 0.19 ENST00000513783.1
UNKL
unkempt family zinc finger-like
chr2_+_220306745 0.19 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr6_-_30712313 0.19 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr19_-_56047661 0.19 ENST00000344158.3
SBK2
SH3 domain binding kinase family, member 2
chr14_-_51562037 0.19 ENST00000338969.5
TRIM9
tripartite motif containing 9
chr17_+_4853442 0.19 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr15_-_60690163 0.19 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr19_-_51568324 0.19 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
KLK13
kallikrein-related peptidase 13
chr2_+_208104351 0.18 ENST00000440326.1
AC007879.7
AC007879.7
chr1_-_202777535 0.18 ENST00000367264.2
KDM5B
lysine (K)-specific demethylase 5B
chr12_+_7341759 0.18 ENST00000455147.2
ENST00000540398.1
PEX5
peroxisomal biogenesis factor 5
chr9_-_86322516 0.18 ENST00000529923.1
UBQLN1
ubiquilin 1
chr11_-_65667884 0.18 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr3_-_12200851 0.18 ENST00000287814.4
TIMP4
TIMP metallopeptidase inhibitor 4
chr2_-_224467002 0.18 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr1_-_28520447 0.18 ENST00000539896.1
PTAFR
platelet-activating factor receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 1.6 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 1.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 1.0 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.9 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.4 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.7 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.9 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 1.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.7 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.4 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.3 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.1 3.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:2000349 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.4 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.3 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.5 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.5 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.3 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.3 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.4 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 0.3 GO:0060426 lung vasculature development(GO:0060426)
0.1 0.2 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.2 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.1 1.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.2 GO:0071288 carbon dioxide transmembrane transport(GO:0035378) cellular response to mercury ion(GO:0071288)
0.1 0.4 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 0.4 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.7 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.2 GO:2000864 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 0.4 GO:0001554 luteolysis(GO:0001554)
0.0 0.3 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.3 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.3 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.4 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.7 GO:0015886 heme transport(GO:0015886)
0.0 1.1 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.2 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.6 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0045937 positive regulation of phosphorus metabolic process(GO:0010562) positive regulation of phosphate metabolic process(GO:0045937)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 1.1 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.4 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.2 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.0 0.5 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.7 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.7 GO:0006298 mismatch repair(GO:0006298)
0.0 0.0 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.2 GO:2000146 negative regulation of cellular component movement(GO:0051271) negative regulation of cell motility(GO:2000146)
0.0 0.2 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 1.1 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.2 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.3 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 1.8 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.2 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.5 GO:0032060 bleb assembly(GO:0032060)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.3 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.2 GO:0044849 estrous cycle(GO:0044849)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.1 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.6 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.3 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.1 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0015820 leucine transport(GO:0015820)
0.0 0.9 GO:0050881 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0097444 spine apparatus(GO:0097444)
0.2 0.9 GO:0005607 laminin-2 complex(GO:0005607)
0.2 1.8 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.6 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 1.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.7 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.4 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.3 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.2 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.6 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:1990462 omegasome(GO:1990462)
0.0 0.4 GO:0031674 I band(GO:0031674)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.7 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 3.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.1 GO:0031430 M band(GO:0031430)
0.0 1.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:1902911 protein kinase complex(GO:1902911)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 1.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 1.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 1.6 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 1.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.6 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 1.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 1.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.5 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.9 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.3 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.3 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0036435 IkappaB kinase activity(GO:0008384) K48-linked polyubiquitin binding(GO:0036435)
0.0 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.7 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.5 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0050659 chondroitin 4-sulfotransferase activity(GO:0047756) N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.7 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.8 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 3.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.7 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6