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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for FOSB

Z-value: 1.29

Motif logo

Transcription factors associated with FOSB

Gene Symbol Gene ID Gene Info
ENSG00000125740.9 FosB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSBhg19_v2_chr19_+_45973360_45973523-0.693.1e-01Click!

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_176923803 1.39 ENST00000506161.1
PDZ and LIM domain 7 (enigma)
chr6_-_35888858 1.37 ENST00000507909.1
SRSF protein kinase 1
chr11_-_102668879 1.36 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr5_-_176923846 1.28 ENST00000506537.1
PDZ and LIM domain 7 (enigma)
chr19_-_47128294 1.16 ENST00000596260.1
ENST00000597185.1
ENST00000598865.1
ENST00000594275.1
ENST00000291294.2
prostaglandin I2 (prostacyclin) receptor (IP)
chr19_-_36019123 1.14 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr19_-_55881741 1.09 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
interleukin 11
chr14_+_77425972 1.07 ENST00000553613.1
RP11-7F17.7
chr3_-_48601206 1.05 ENST00000273610.3
urocortin 2
chr17_+_7482785 0.96 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68 molecule
chrX_+_48687283 0.91 ENST00000338270.1
ES cell expressed Ras
chr19_-_44174330 0.88 ENST00000340093.3
plasminogen activator, urokinase receptor
chr19_-_44174305 0.88 ENST00000601723.1
ENST00000339082.3
plasminogen activator, urokinase receptor
chr18_+_61144160 0.83 ENST00000489441.1
ENST00000424602.1
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr19_-_19739321 0.83 ENST00000588461.1
lysophosphatidic acid receptor 2
chr15_-_44486632 0.81 ENST00000484674.1
FERM domain containing 5
chr17_-_39769005 0.81 ENST00000301653.4
ENST00000593067.1
keratin 16
chr6_-_169563013 0.80 ENST00000439703.1
RP11-417E7.1
chr17_-_8021710 0.78 ENST00000380149.1
ENST00000448843.2
arachidonate lipoxygenase 3
chr3_-_196065374 0.78 ENST00000454715.1
transmembrane 4 L six family member 19
chr1_+_17634689 0.77 ENST00000375453.1
ENST00000375448.4
peptidyl arginine deiminase, type IV
chr16_-_30997533 0.77 ENST00000602217.1
Uncharacterized protein
chr2_+_169926047 0.75 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr18_+_21452804 0.74 ENST00000269217.6
laminin, alpha 3
chr3_-_48632593 0.73 ENST00000454817.1
ENST00000328333.8
collagen, type VII, alpha 1
chr2_+_87755054 0.72 ENST00000423846.1
long intergenic non-protein coding RNA 152
chr1_-_153521714 0.71 ENST00000368713.3
S100 calcium binding protein A3
chr5_-_139930713 0.70 ENST00000602657.1
steroid receptor RNA activator 1
chr3_+_48507210 0.69 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
three prime repair exonuclease 1
chr19_-_35981358 0.68 ENST00000484218.2
ENST00000338897.3
keratinocyte differentiation-associated protein
chr9_+_131902346 0.67 ENST00000432124.1
ENST00000435305.1
protein phosphatase 2A activator, regulatory subunit 4
chr17_+_73717407 0.65 ENST00000579662.1
integrin, beta 4
chr3_-_196065248 0.64 ENST00000446879.1
ENST00000273695.3
transmembrane 4 L six family member 19
chr17_-_18908040 0.64 ENST00000388995.6
family with sequence similarity 83, member G
chr18_+_21452964 0.63 ENST00000587184.1
laminin, alpha 3
chr17_+_74381343 0.63 ENST00000392496.3
sphingosine kinase 1
chr11_-_66103932 0.63 ENST00000311320.4
Ras and Rab interactor 1
chr17_+_73717516 0.63 ENST00000200181.3
ENST00000339591.3
integrin, beta 4
chr8_-_123139423 0.62 ENST00000523792.1
RP11-398G24.2
chr3_+_48507621 0.62 ENST00000456089.1
three prime repair exonuclease 1
chr17_+_73717551 0.58 ENST00000450894.3
integrin, beta 4
chr12_-_118628315 0.58 ENST00000540561.1
TAO kinase 3
chr7_+_55177416 0.56 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr11_-_65150103 0.56 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
solute carrier family 25, member 45
chr1_-_45272951 0.55 ENST00000372200.1
Tctex1 domain containing 4
chr2_+_27505260 0.55 ENST00000380075.2
ENST00000296098.4
tripartite motif containing 54
chr4_-_69083720 0.53 ENST00000432593.3
TMPRSS11B N-terminal like
chr6_+_47666275 0.53 ENST00000327753.3
ENST00000283303.2
G protein-coupled receptor 115
chr12_+_52695617 0.52 ENST00000293525.5
keratin 86
chr19_+_7953417 0.52 ENST00000600345.1
ENST00000598224.1
leucine rich repeat containing 8 family, member E
chr22_+_37959647 0.51 ENST00000415670.1
CDC42 effector protein (Rho GTPase binding) 1
chr15_+_67458357 0.51 ENST00000537194.2
SMAD family member 3
chr7_+_143078379 0.50 ENST00000449630.1
ENST00000457235.1
zyxin
chr7_-_130597935 0.49 ENST00000447307.1
ENST00000418546.1
microRNA 29a
chr16_-_4665023 0.49 ENST00000591897.1
UBA-like domain containing 1
chr12_-_54813229 0.48 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr17_+_28256874 0.47 ENST00000541045.1
ENST00000536908.2
EF-hand calcium binding domain 5
chr7_-_150721570 0.47 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
autophagy related 9B
chr17_+_7344057 0.46 ENST00000575398.1
ENST00000575082.1
fibroblast growth factor 11
chr12_+_7023735 0.46 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr16_-_4664860 0.46 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBA-like domain containing 1
chr17_+_72426891 0.46 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr5_+_135394840 0.45 ENST00000503087.1
transforming growth factor, beta-induced, 68kDa
chr3_+_183894566 0.45 ENST00000439647.1
adaptor-related protein complex 2, mu 1 subunit
chr7_+_871559 0.45 ENST00000421580.1
Sad1 and UNC84 domain containing 1
chr5_+_135383008 0.45 ENST00000508767.1
ENST00000604555.1
transforming growth factor, beta-induced, 68kDa
chr12_-_49351228 0.44 ENST00000541959.1
ENST00000447318.2
ADP-ribosylation factor 3
chr15_+_57211318 0.42 ENST00000557947.1
transcription factor 12
chr4_-_89079817 0.42 ENST00000505480.1
ATP-binding cassette, sub-family G (WHITE), member 2
chr15_-_76304731 0.42 ENST00000394907.3
neuregulin 4
chr14_-_96180435 0.41 ENST00000556450.1
ENST00000555202.1
ENST00000554012.1
ENST00000402399.1
T-cell leukemia/lymphoma 1A
chr15_-_60690163 0.41 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
annexin A2
chr3_+_36421971 0.41 ENST00000457375.2
ENST00000434649.1
SH3 and cysteine rich domain
chr19_-_6057282 0.41 ENST00000592281.1
regulatory factor X, 2 (influences HLA class II expression)
chr8_+_99076750 0.40 ENST00000545282.1
chromosome 8 open reading frame 47
chr12_+_7023491 0.39 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr1_-_153935791 0.39 ENST00000429040.1
solute carrier family 39 (zinc transporter), member 1
chr5_-_66942617 0.39 ENST00000507298.1
RP11-83M16.5
chr3_+_183894737 0.37 ENST00000432591.1
ENST00000431779.1
adaptor-related protein complex 2, mu 1 subunit
chr2_-_190927447 0.37 ENST00000260950.4
myostatin
chr15_+_67418047 0.37 ENST00000540846.2
SMAD family member 3
chr19_-_51568324 0.37 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
kallikrein-related peptidase 13
chr2_+_87754989 0.37 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
long intergenic non-protein coding RNA 152
chr11_-_64527425 0.36 ENST00000377432.3
phosphorylase, glycogen, muscle
chr15_+_101459420 0.36 ENST00000388948.3
ENST00000284395.5
ENST00000534045.1
ENST00000532029.2
leucine-rich repeat kinase 1
chr16_+_30751953 0.36 ENST00000483578.1
RP11-2C24.4
chr7_+_73624327 0.35 ENST00000361082.3
ENST00000275635.7
ENST00000470709.1
linker for activation of T cells family, member 2
chr12_-_118628350 0.35 ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr12_-_120805872 0.35 ENST00000546985.1
musashi RNA-binding protein 1
chr17_+_79650962 0.35 ENST00000329138.4
hepatocyte growth factor-regulated tyrosine kinase substrate
chr12_-_49351148 0.34 ENST00000398092.4
ENST00000539611.1
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr1_-_153521597 0.34 ENST00000368712.1
S100 calcium binding protein A3
chr19_-_39264072 0.34 ENST00000599035.1
ENST00000378626.4
lectin, galactoside-binding, soluble, 7
chr11_-_65667884 0.32 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr1_-_95007193 0.32 ENST00000370207.4
ENST00000334047.7
coagulation factor III (thromboplastin, tissue factor)
chr17_+_65375082 0.32 ENST00000584471.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr17_-_73401728 0.32 ENST00000316804.5
ENST00000316615.5
growth factor receptor-bound protein 2
chr17_-_73401567 0.31 ENST00000392562.1
growth factor receptor-bound protein 2
chr10_+_1102303 0.31 ENST00000381329.1
WD repeat domain 37
chr5_+_81575281 0.31 ENST00000380167.4
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr9_-_73029540 0.31 ENST00000377126.2
Kruppel-like factor 9
chr12_+_53693466 0.31 ENST00000267103.5
ENST00000548632.1
chromosome 12 open reading frame 10
chr17_-_70417365 0.30 ENST00000580948.1
long intergenic non-protein coding RNA 511
chr2_-_136633940 0.30 ENST00000264156.2
minichromosome maintenance complex component 6
chr19_-_36499521 0.29 ENST00000397428.3
ENST00000503121.1
ENST00000340477.5
ENST00000324444.3
ENST00000490730.1
spectrin repeat containing, nuclear envelope family member 4
chr16_-_72206034 0.29 ENST00000537465.1
ENST00000237353.10
polyamine modulated factor 1 binding protein 1
chr1_-_153935738 0.29 ENST00000417348.1
solute carrier family 39 (zinc transporter), member 1
chr3_+_157828152 0.29 ENST00000476899.1
arginine/serine-rich coiled-coil 1
chr5_-_90610200 0.29 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
lung cancer associated transcript 1 (non-protein coding)
RP11-213H15.4
chr10_+_75668916 0.28 ENST00000481390.1
plasminogen activator, urokinase
chr1_+_26606608 0.28 ENST00000319041.6
SH3 domain binding glutamic acid-rich protein like 3
chr12_-_49351303 0.28 ENST00000256682.4
ADP-ribosylation factor 3
chr11_-_47198380 0.28 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ADP-ribosylation factor GTPase activating protein 2
chr22_-_39151947 0.27 ENST00000216064.4
Sad1 and UNC84 domain containing 2
chr11_-_65667997 0.27 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr19_+_47104553 0.27 ENST00000598871.1
ENST00000594523.1
calmodulin 3 (phosphorylase kinase, delta)
chr6_-_30685214 0.26 ENST00000425072.1
mediator of DNA-damage checkpoint 1
chr1_-_113247543 0.26 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr15_+_45938079 0.26 ENST00000561493.1
sulfide quinone reductase-like (yeast)
chr16_+_57844549 0.26 ENST00000564282.1
uncharacterized protein LOC388282
chr1_+_3385085 0.25 ENST00000445297.1
Rho guanine nucleotide exchange factor (GEF) 16
chr15_-_72521017 0.25 ENST00000561609.1
pyruvate kinase, muscle
chr7_+_120590803 0.25 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
inhibitor of growth family, member 3
chr19_+_7953384 0.24 ENST00000306708.6
leucine rich repeat containing 8 family, member E
chr3_-_141747950 0.24 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr12_+_58176525 0.24 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
Ts translation elongation factor, mitochondrial
chr16_-_67281413 0.24 ENST00000258201.4
formin homology 2 domain containing 1
chr22_-_36761081 0.23 ENST00000456729.1
ENST00000401701.1
myosin, heavy chain 9, non-muscle
chr8_-_133772794 0.23 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
transmembrane protein 71
chr21_+_30672433 0.23 ENST00000451655.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr1_-_24126023 0.23 ENST00000429356.1
UDP-galactose-4-epimerase
chr5_+_139493665 0.22 ENST00000331327.3
purine-rich element binding protein A
chr7_+_73624276 0.22 ENST00000475494.1
ENST00000398475.1
linker for activation of T cells family, member 2
chr2_+_152214098 0.22 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr11_-_65430251 0.22 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr2_+_16080659 0.22 ENST00000281043.3
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr19_-_36004543 0.22 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
dermokine
chr17_-_59668550 0.21 ENST00000521764.1
nascent polypeptide-associated complex alpha subunit 2
chr2_+_135596180 0.21 ENST00000283054.4
ENST00000392928.1
aminocarboxymuconate semialdehyde decarboxylase
chr17_-_48785216 0.20 ENST00000285243.6
ankyrin repeat domain 40
chr5_-_41794313 0.20 ENST00000512084.1
3-oxoacid CoA transferase 1
chrX_-_153285251 0.20 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr22_-_39151434 0.20 ENST00000439339.1
Sad1 and UNC84 domain containing 2
chr20_+_44637526 0.20 ENST00000372330.3
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr17_-_27045165 0.20 ENST00000436730.3
ENST00000450529.1
ENST00000583538.1
ENST00000419712.3
ENST00000580843.2
ENST00000582934.1
ENST00000415040.2
ENST00000353676.5
ENST00000453384.3
ENST00000447716.1
RAB34, member RAS oncogene family
chr13_-_36429763 0.19 ENST00000379893.1
doublecortin-like kinase 1
chr15_+_74528630 0.19 ENST00000398814.3
coiled-coil domain containing 33
chr12_+_64845864 0.19 ENST00000538890.1
TANK-binding kinase 1
chr11_-_47206965 0.19 ENST00000525725.1
protein kinase C and casein kinase substrate in neurons 3
chr5_-_138534071 0.19 ENST00000394817.2
SIL1 nucleotide exchange factor
chr1_-_9953295 0.19 ENST00000377258.1
catenin, beta interacting protein 1
chr1_+_223889310 0.18 ENST00000434648.1
calpain 2, (m/II) large subunit
chr22_-_32058166 0.18 ENST00000435900.1
ENST00000336566.4
phosphatidylserine decarboxylase
chr12_-_51402984 0.18 ENST00000545993.2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr17_-_18161870 0.18 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
flightless I homolog (Drosophila)
chr8_-_68658578 0.18 ENST00000518549.1
ENST00000297770.4
ENST00000297769.4
carboxypeptidase A6
chr22_+_39916558 0.18 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr6_+_106959718 0.17 ENST00000369066.3
absent in melanoma 1
chr11_-_66103867 0.17 ENST00000424433.2
Ras and Rab interactor 1
chr19_+_36630454 0.17 ENST00000246533.3
calpain, small subunit 1
chr12_+_12938541 0.17 ENST00000356591.4
apolipoprotein L domain containing 1
chr3_-_52869205 0.17 ENST00000446157.2
musculoskeletal, embryonic nuclear protein 1
chr2_-_218706877 0.17 ENST00000446688.1
tensin 1
chr4_+_108746282 0.17 ENST00000503862.1
sphingomyelin synthase 2
chr1_+_27189631 0.17 ENST00000339276.4
stratifin
chr17_+_46970178 0.17 ENST00000393366.2
ENST00000506855.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr22_-_32058416 0.17 ENST00000439502.2
phosphatidylserine decarboxylase
chr16_+_89724434 0.16 ENST00000568929.1
spermatogenesis associated 33
chr9_-_130637244 0.16 ENST00000373156.1
adenylate kinase 1
chr6_+_292051 0.16 ENST00000344450.5
dual specificity phosphatase 22
chr5_-_41794663 0.16 ENST00000510634.1
3-oxoacid CoA transferase 1
chr17_+_74734052 0.16 ENST00000590514.1
major facilitator superfamily domain containing 11
chr4_+_166128836 0.16 ENST00000511305.1
kelch-like family member 2
chr11_-_46848393 0.16 ENST00000526496.1
cytoskeleton associated protein 5
chr17_-_39942940 0.15 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
junction plakoglobin
chr7_-_42276612 0.15 ENST00000395925.3
ENST00000437480.1
GLI family zinc finger 3
chr17_-_27045405 0.15 ENST00000430132.2
RAB34, member RAS oncogene family
chr20_+_48429233 0.15 ENST00000417961.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr11_-_47207390 0.15 ENST00000539589.1
ENST00000528462.1
protein kinase C and casein kinase substrate in neurons 3
chr6_+_159291090 0.15 ENST00000367073.4
ENST00000608817.1
chromosome 6 open reading frame 99
chr7_+_116312411 0.14 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chr2_+_28615669 0.14 ENST00000379619.1
ENST00000264716.4
FOS-like antigen 2
chr19_+_47104493 0.14 ENST00000291295.9
ENST00000597743.1
calmodulin 3 (phosphorylase kinase, delta)
chr8_-_30585217 0.14 ENST00000520888.1
ENST00000414019.1
glutathione reductase
chr4_+_41983713 0.14 ENST00000333141.5
DDB1 and CUL4 associated factor 4-like 1
chr17_-_27045427 0.14 ENST00000301043.6
ENST00000412625.1
RAB34, member RAS oncogene family
chr10_+_18549645 0.14 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr2_+_216974020 0.14 ENST00000392132.2
ENST00000417391.1
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr4_+_71588372 0.14 ENST00000536664.1
RUN and FYVE domain containing 3
chr4_+_74606223 0.14 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr10_+_85899196 0.14 ENST00000372134.3
growth hormone inducible transmembrane protein
chr1_-_179112189 0.13 ENST00000512653.1
ENST00000344730.3
c-abl oncogene 2, non-receptor tyrosine kinase
chr5_-_138533973 0.13 ENST00000507002.1
ENST00000505830.1
ENST00000508639.1
ENST00000265195.5
SIL1 nucleotide exchange factor
chr3_-_18466787 0.13 ENST00000338745.6
ENST00000450898.1
SATB homeobox 1
chr16_-_67867749 0.13 ENST00000566758.1
ENST00000445712.2
ENST00000219172.3
ENST00000564817.1
centromere protein T
chr3_+_183903811 0.13 ENST00000429586.2
ENST00000292808.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr21_-_35340759 0.13 ENST00000607953.1
AP000569.9
chr8_-_70745575 0.13 ENST00000524945.1
solute carrier organic anion transporter family, member 5A1
chr9_-_35112376 0.13 ENST00000488109.2
family with sequence similarity 214, member B
chr1_+_203096831 0.13 ENST00000337894.4
adenosine A1 receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 1.5 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 1.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.2 0.8 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.8 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.9 GO:0035878 nail development(GO:0035878)
0.1 0.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.4 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.4 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.5 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.9 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.1 0.6 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.8 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 1.0 GO:0051546 keratinocyte migration(GO:0051546)
0.1 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0032796 uropod organization(GO:0032796)
0.0 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0051414 response to cortisol(GO:0051414)
0.0 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 1.6 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 2.6 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.2 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 1.1 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:1904430 cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.6 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.0 GO:0072229 proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 1.3 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.9 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.0 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.3 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 1.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.4 GO:0005980 glycogen catabolic process(GO:0005980)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.7 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 1.4 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.6 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 1.8 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 2.0 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 1.2 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.7 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.0 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.7 GO:0045095 keratin filament(GO:0045095)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.3 1.8 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 1.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 0.8 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.2 0.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 1.9 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.6 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.2 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.1 0.3 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 1.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.6 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 3.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 1.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 3.4 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.9 REACTOME AMYLOIDS Genes involved in Amyloids