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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for ETV6
Z-value: 1.71
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Transcription factors associated with ETV6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETV6 | hg19_v2_chr12_+_11802753_11802834 | -0.67 | 3.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_96971259 Show fit | 1.07 |
ENST00000349783.5
|
small nuclear ribonucleoprotein 200kDa (U5) |
|
| chr6_+_31620191 Show fit | 1.04 |
ENST00000375918.2
ENST00000375920.4 |
apolipoprotein M |
|
| chr18_-_12377001 Show fit | 0.92 |
ENST00000590811.1
|
AFG3-like AAA ATPase 2 |
|
| chr17_+_45908974 Show fit | 0.90 |
ENST00000269025.4
|
leucine rich repeat containing 46 |
|
| chr11_-_64851496 Show fit | 0.79 |
ENST00000404147.3
ENST00000275517.3 |
cell division cycle associated 5 |
|
| chr11_-_67205538 Show fit | 0.79 |
ENST00000326294.3
|
protein tyrosine phosphatase, receptor type, C-associated protein |
|
| chr12_-_56223363 Show fit | 0.78 |
ENST00000546957.1
|
DnaJ (Hsp40) homolog, subfamily C, member 14 |
|
| chr14_+_35451880 Show fit | 0.77 |
ENST00000554803.1
ENST00000555746.1 |
signal recognition particle 54kDa |
|
| chrX_+_69509927 Show fit | 0.63 |
ENST00000374403.3
|
kinesin family member 4A |
|
| chr3_+_149191723 Show fit | 0.61 |
ENST00000305354.4
|
transmembrane 4 L six family member 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ETV6
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.6 | GO:0000354 | cis assembly of pre-catalytic spliceosome(GO:0000354) |
| 0.1 | 1.3 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.1 | 1.2 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.3 | 1.1 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 0.3 | 1.0 | GO:0034445 | regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) |
| 0.3 | 1.0 | GO:0034402 | recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402) |
| 0.1 | 0.9 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.1 | 0.9 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.3 | 0.8 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
| 0.3 | 0.8 | GO:0034085 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
| 0.0 | 1.2 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 1.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.0 | 1.1 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.3 | 1.0 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.3 | 0.9 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.0 | 0.8 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.0 | 0.8 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.0 | 0.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.2 | 0.7 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 1.3 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 1.3 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.1 | 1.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.0 | 1.0 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 0.8 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.8 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.2 | 0.7 | GO:0016429 | tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429) |
| 0.1 | 0.7 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.1 | 0.7 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.5 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.5 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 1.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.9 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.8 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 0.8 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 0.7 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 0.7 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.7 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 0.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.5 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |