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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for ETS1
Z-value: 1.48
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Transcription factors associated with ETS1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETS1 | hg19_v2_chr11_-_128457446_128457461 | 0.96 | 3.6e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ETS1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.0 | GO:1904327 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.0 | 1.3 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.1 | 1.2 | GO:0030578 | PML body organization(GO:0030578) |
| 0.4 | 1.1 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.0 | 1.1 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.1 | 1.0 | GO:0033183 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.2 | 0.9 | GO:0010979 | regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369) |
| 0.1 | 0.9 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 0.0 | 0.9 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.0 | 0.9 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.2 | 2.0 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.0 | 2.0 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
| 0.0 | 1.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 0.9 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 0.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 0.8 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 0.1 | 0.8 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.1 | 0.8 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.0 | 0.8 | GO:0071141 | SMAD protein complex(GO:0071141) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.0 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 1.5 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 1.3 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.1 | 1.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.1 | 1.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.2 | 1.1 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.0 | 1.1 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 1.0 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.0 | 1.0 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 1.0 | GO:0042162 | telomeric DNA binding(GO:0042162) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 1.2 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 1.1 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 1.0 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 1.0 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 0.9 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.9 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.8 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 0.8 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 0.7 | PID ARF 3PATHWAY | Arf1 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 1.4 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 1.2 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 1.1 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.0 | 1.0 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.9 | REACTOME SIGNALING BY NOTCH2 | Genes involved in Signaling by NOTCH2 |
| 0.1 | 0.8 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.0 | 0.8 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.8 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 0.8 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |