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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for EOMES

Z-value: 1.52

Motif logo

Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
ENSG00000163508.8 eomesodermin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EOMEShg19_v2_chr3_-_27763803_277638220.732.7e-01Click!

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_51153045 1.36 ENST00000458538.1
chromosome 19 open reading frame 81
chr12_+_30948600 1.03 ENST00000550292.1
long intergenic non-protein coding RNA 941
chr9_+_132044730 0.86 ENST00000455981.1
RP11-344B5.2
chr3_-_113775328 0.70 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407
chr10_-_9801179 0.65 ENST00000419836.1
RP5-1051H14.2
chr8_-_121825088 0.62 ENST00000520717.1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr14_+_77843459 0.61 ENST00000216471.4
sterile alpha motif domain containing 15
chr6_-_86303833 0.61 ENST00000505648.1
sorting nexin 14
chr22_-_50970506 0.60 ENST00000428989.2
ENST00000403326.1
outer dense fiber of sperm tails 3B
chr19_-_39360561 0.57 ENST00000593809.1
ENST00000593424.1
Ras and Rab interactor-like
chr1_+_193028717 0.55 ENST00000415442.2
ENST00000506303.1
TROVE domain family, member 2
chr2_-_163175133 0.53 ENST00000421365.2
ENST00000263642.2
interferon induced with helicase C domain 1
chr2_-_191878874 0.52 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
signal transducer and activator of transcription 1, 91kDa
chr4_-_76555657 0.50 ENST00000307465.4
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chrM_+_8366 0.50 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr4_-_129207942 0.48 ENST00000503588.1
progesterone receptor membrane component 2
chr8_-_109260897 0.47 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
eukaryotic translation initiation factor 3, subunit E
chrX_-_114953669 0.46 ENST00000449327.1
Uncharacterized protein
chr12_+_95611536 0.46 ENST00000549002.1
vezatin, adherens junctions transmembrane protein
chrX_-_119695279 0.43 ENST00000336592.6
cullin 4B
chr6_-_86303523 0.43 ENST00000513865.1
ENST00000369627.2
ENST00000514419.1
ENST00000509338.1
ENST00000314673.3
ENST00000346348.3
sorting nexin 14
chrX_+_106045891 0.39 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1 domain family, member 8B (with GRAM domain)
chr8_-_90996837 0.39 ENST00000519426.1
ENST00000265433.3
nibrin
chr3_-_122102065 0.38 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
coiled-coil domain containing 58
chr4_-_129208030 0.36 ENST00000503872.1
progesterone receptor membrane component 2
chr6_-_131949305 0.36 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
mediator complex subunit 23
chr6_-_131949200 0.35 ENST00000539158.1
ENST00000368058.1
mediator complex subunit 23
chr11_+_117947724 0.35 ENST00000534111.1
transmembrane protease, serine 4
chr13_-_20767037 0.35 ENST00000382848.4
gap junction protein, beta 2, 26kDa
chr9_+_139738867 0.34 ENST00000436881.1
chromosome 9 open reading frame 172
chr15_+_89182156 0.34 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr16_+_24550857 0.33 ENST00000568015.1
retinoblastoma binding protein 6
chr1_+_60280458 0.32 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr15_+_77713222 0.32 ENST00000558176.1
high mobility group 20A
chr1_+_113217309 0.32 ENST00000544796.1
ENST00000369644.1
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr8_-_144099795 0.32 ENST00000522060.1
ENST00000517833.1
ENST00000502167.2
ENST00000518831.1
RP11-273G15.2
chr17_-_8066843 0.31 ENST00000404970.3
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr3_+_156544057 0.31 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
leucine, glutamate and lysine rich 1
chr17_-_4463856 0.31 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
gamma-glutamyltransferase 6
chr3_+_113775594 0.31 ENST00000479882.1
ENST00000493014.1
queuine tRNA-ribosyltransferase domain containing 1
chr3_-_143567262 0.30 ENST00000474151.1
ENST00000316549.6
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr20_-_35274548 0.30 ENST00000262866.4
Src-like-adaptor 2
chr8_-_8318847 0.30 ENST00000521218.1
CTA-398F10.2
chr12_-_127630534 0.30 ENST00000535022.1
RP11-575F12.2
chr13_-_107220455 0.30 ENST00000400198.3
arginine and glutamate rich 1
chr17_+_74723031 0.29 ENST00000586200.1
methyltransferase like 23
chr1_-_186344802 0.29 ENST00000451586.1
translocated promoter region, nuclear basket protein
chr17_-_42906965 0.29 ENST00000586267.1
gap junction protein, gamma 1, 45kDa
chr1_-_193029192 0.28 ENST00000417752.1
ENST00000367452.4
ubiquitin carboxyl-terminal hydrolase L5
chr1_+_246729815 0.28 ENST00000366511.1
consortin, connexin sorting protein
chr22_-_36850991 0.28 ENST00000442579.1
RP5-1119A7.14
chr16_-_3086927 0.28 ENST00000572449.1
coiled-coil domain containing 64B
chr5_+_75699149 0.27 ENST00000379730.3
IQ motif containing GTPase activating protein 2
chr18_-_19284724 0.27 ENST00000580981.1
ENST00000289119.2
abhydrolase domain containing 3
chr5_+_68788594 0.27 ENST00000396442.2
ENST00000380766.2
occludin
chr8_-_90996459 0.27 ENST00000517337.1
ENST00000409330.1
nibrin
chr8_+_48173556 0.26 ENST00000524006.1
scaffolding protein involved in DNA repair
chr2_-_69664586 0.26 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr14_-_59950724 0.26 ENST00000481608.1
L-3-hydroxyproline dehydratase (trans-)
chr16_+_53407383 0.26 ENST00000566383.1
RP11-44F14.2
chr14_-_67878917 0.26 ENST00000216446.4
pleckstrin 2
chr2_-_31637560 0.26 ENST00000379416.3
xanthine dehydrogenase
chr15_+_63414017 0.26 ENST00000413507.2
lactamase, beta
chrX_+_47083037 0.26 ENST00000523034.1
cyclin-dependent kinase 16
chr15_+_89182178 0.26 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr3_-_167452298 0.26 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
programmed cell death 10
chr14_-_53162361 0.25 ENST00000395686.3
ERO1-like (S. cerevisiae)
chr12_+_93965609 0.25 ENST00000549887.1
ENST00000551556.1
suppressor of cytokine signaling 2
chr4_-_54930790 0.25 ENST00000263921.3
cysteine-rich hydrophobic domain 2
chrX_-_47004437 0.25 ENST00000276062.8
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr4_+_25314388 0.25 ENST00000302874.4
zinc finger, CCHC domain containing 4
chr2_+_230787201 0.25 ENST00000283946.3
F-box protein 36
chr15_-_56285742 0.24 ENST00000435532.3
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr3_-_180707306 0.24 ENST00000479269.1
DnaJ (Hsp40) homolog, subfamily C, member 19
chr1_-_244615425 0.24 ENST00000366535.3
adenylosuccinate synthase
chr1_-_205744205 0.24 ENST00000446390.2
RAB7, member RAS oncogene family-like 1
chr6_-_27440837 0.24 ENST00000211936.6
zinc finger protein 184
chr21_-_47604318 0.24 ENST00000291672.5
ENST00000330205.6
spermatogenesis and centriole associated 1-like
chr3_-_167452614 0.24 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
programmed cell death 10
chr2_-_179315786 0.23 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
protein kinase, interferon-inducible double stranded RNA dependent activator
chr10_+_95653687 0.23 ENST00000371408.3
ENST00000427197.1
solute carrier family 35, member G1
chr2_-_8723918 0.23 ENST00000454224.1
AC011747.4
chr15_-_45459704 0.23 ENST00000558039.1
CTD-2651B20.1
chr2_+_201171268 0.23 ENST00000423749.1
ENST00000428692.1
ENST00000457757.1
ENST00000453663.1
spermatogenesis associated, serine-rich 2-like
chr8_-_17941575 0.23 ENST00000417108.2
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr10_-_101673782 0.23 ENST00000422692.1
dynamin binding protein
chr3_-_183735651 0.22 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr21_+_34619079 0.22 ENST00000433395.2
AP000295.9
chr10_-_13342051 0.22 ENST00000479604.1
phytanoyl-CoA 2-hydroxylase
chr3_-_88108212 0.22 ENST00000482016.1
CGG triplet repeat binding protein 1
chr12_+_95611569 0.22 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
vezatin, adherens junctions transmembrane protein
chr3_-_131221790 0.22 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr18_-_21977748 0.22 ENST00000399441.4
ENST00000319481.3
oxysterol binding protein-like 1A
chr3_-_64673668 0.22 ENST00000498707.1
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr19_-_55677920 0.22 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
dynein, axonemal, assembly factor 3
chr12_-_69326940 0.21 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
carboxypeptidase M
chr2_-_148778258 0.21 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
origin recognition complex, subunit 4
chr2_+_148778570 0.21 ENST00000407073.1
methyl-CpG binding domain protein 5
chr4_-_165305086 0.21 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr1_+_186344883 0.21 ENST00000367470.3
chromosome 1 open reading frame 27
chr7_-_93519471 0.21 ENST00000451238.1
tissue factor pathway inhibitor 2
chr4_-_1657135 0.21 ENST00000489029.1
family with sequence similarity 53, member A
chr4_-_76862117 0.21 ENST00000507956.1
ENST00000507187.2
ENST00000399497.3
ENST00000286733.4
N-acylethanolamine acid amidase
chr7_-_93520259 0.21 ENST00000222543.5
tissue factor pathway inhibitor 2
chr3_-_52868931 0.20 ENST00000486659.1
musculoskeletal, embryonic nuclear protein 1
chr7_-_93520191 0.20 ENST00000545378.1
tissue factor pathway inhibitor 2
chr6_+_154360616 0.20 ENST00000229768.5
ENST00000419506.2
ENST00000524163.1
ENST00000414028.2
ENST00000435918.2
ENST00000337049.4
opioid receptor, mu 1
chr17_+_48133330 0.20 ENST00000544892.1
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr12_-_6756559 0.20 ENST00000536350.1
ENST00000414226.2
ENST00000546114.1
acrosin binding protein
chr7_+_87505544 0.20 ENST00000265728.1
DBF4 homolog (S. cerevisiae)
chr6_-_27440460 0.20 ENST00000377419.1
zinc finger protein 184
chr7_+_106810165 0.20 ENST00000468401.1
ENST00000497535.1
ENST00000485846.1
HMG-box transcription factor 1
chr12_+_6554021 0.20 ENST00000266557.3
CD27 molecule
chr8_+_9413410 0.20 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr18_+_76829441 0.20 ENST00000458297.2
ATPase, class II, type 9B
chr7_-_66460563 0.19 ENST00000246868.2
Shwachman-Bodian-Diamond syndrome
chr19_+_51152702 0.19 ENST00000425202.1
chromosome 19 open reading frame 81
chr15_-_43622736 0.19 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
leucine carboxyl methyltransferase 2
chr1_+_33283043 0.19 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100P binding protein
chr6_+_80816372 0.19 ENST00000545529.1
branched chain keto acid dehydrogenase E1, beta polypeptide
chr17_-_18585131 0.19 ENST00000443457.1
ENST00000583002.1
zinc finger protein 286B
chr17_-_60005329 0.19 ENST00000251334.6
integrator complex subunit 2
chr6_-_41888843 0.19 ENST00000434077.1
ENST00000409312.1
mediator complex subunit 20
chr11_-_8615507 0.19 ENST00000431279.2
ENST00000418597.1
serine/threonine kinase 33
chr3_-_50649192 0.19 ENST00000443053.2
ENST00000348721.3
cytokine inducible SH2-containing protein
chr14_-_51135036 0.19 ENST00000324679.4
salvador homolog 1 (Drosophila)
chr12_-_68797580 0.19 ENST00000539404.1
RP11-81H14.2
chr1_-_226065330 0.18 ENST00000436966.1
transmembrane protein 63A
chr4_+_187813673 0.18 ENST00000606881.1
RP11-11N5.3
chr11_+_35201826 0.18 ENST00000531873.1
CD44 molecule (Indian blood group)
chr19_+_35532612 0.18 ENST00000600390.1
ENST00000597419.1
hepsin
chr1_-_95285764 0.18 ENST00000414374.1
ENST00000421997.1
ENST00000418366.2
ENST00000452922.1
long intergenic non-protein coding RNA 1057
chr11_-_22851367 0.18 ENST00000354193.4
small VCP/p97-interacting protein
chr1_+_28099700 0.18 ENST00000440806.2
syntaxin 12
chr15_+_85147127 0.18 ENST00000541040.1
ENST00000538076.1
ENST00000485222.2
zinc finger and SCAN domain containing 2
chr3_+_9944303 0.18 ENST00000421412.1
ENST00000295980.3
interleukin 17 receptor E
chr18_-_47018869 0.18 ENST00000583036.1
ENST00000580261.1
ribosomal protein L17
chr3_+_9944492 0.18 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
interleukin 17 receptor E
chr3_+_132379154 0.18 ENST00000468022.1
ENST00000473651.1
ENST00000494238.2
ubiquitin-like modifier activating enzyme 5
chr18_+_43246028 0.18 ENST00000589658.1
solute carrier family 14 (urea transporter), member 2
chr14_-_92572894 0.17 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ataxin 3
chr6_+_30034966 0.17 ENST00000376769.2
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr15_+_90728145 0.17 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr11_-_70672645 0.17 ENST00000423696.2
SH3 and multiple ankyrin repeat domains 2
chr1_-_184943610 0.17 ENST00000367511.3
family with sequence similarity 129, member A
chr2_-_161350305 0.17 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr15_+_83776137 0.17 ENST00000322019.9
transmembrane 6 superfamily member 1
chr1_+_186344945 0.17 ENST00000419367.3
ENST00000287859.6
chromosome 1 open reading frame 27
chr4_-_140222358 0.17 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr2_-_179315453 0.17 ENST00000432031.2
protein kinase, interferon-inducible double stranded RNA dependent activator
chr11_-_45928830 0.17 ENST00000449465.1
chromosome 11 open reading frame 94
chr17_+_74722912 0.17 ENST00000589977.1
ENST00000591571.1
ENST00000592849.1
ENST00000586738.1
ENST00000588783.1
ENST00000588563.1
ENST00000586752.1
ENST00000588302.1
ENST00000590964.1
ENST00000341249.6
ENST00000588822.1
methyltransferase like 23
chr2_-_148778323 0.17 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr11_-_102323740 0.17 ENST00000398136.2
transmembrane protein 123
chr11_-_102323489 0.16 ENST00000361236.3
transmembrane protein 123
chr5_-_112630598 0.16 ENST00000302475.4
mutated in colorectal cancers
chrM_+_10053 0.16 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chr12_-_42632127 0.16 ENST00000555248.2
YY1 associated factor 2
chr16_+_85936295 0.16 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
interferon regulatory factor 8
chr7_-_91875358 0.16 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1, ankyrin repeat containing
chr5_+_96271141 0.16 ENST00000231368.5
leucyl/cystinyl aminopeptidase
chr6_-_41701428 0.16 ENST00000424495.1
ENST00000445700.1
transcription factor EB
chrX_-_102757802 0.16 ENST00000372633.1
RAB40A, member RAS oncogene family
chr13_-_102068706 0.16 ENST00000251127.6
sodium leak channel, non-selective
chr13_+_73302047 0.16 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
bora, aurora kinase A activator
chr14_+_32546145 0.16 ENST00000556611.1
ENST00000539826.2
Rho GTPase activating protein 5
chr19_-_58238958 0.16 ENST00000596939.1
ENST00000335820.3
ENST00000317398.6
zinc finger protein 671
chr2_-_235405168 0.16 ENST00000339728.3
ADP-ribosylation factor-like 4C
chr15_+_40532723 0.16 ENST00000558878.1
ENST00000558183.1
p21 protein (Cdc42/Rac)-activated kinase 6
chr15_+_83776324 0.16 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
transmembrane 6 superfamily member 1
chr5_-_102455801 0.16 ENST00000508629.1
ENST00000399004.2
gypsy retrotransposon integrase 1
chr17_+_6659354 0.16 ENST00000574907.1
XIAP associated factor 1
chr14_+_57857262 0.16 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr1_+_37940153 0.16 ENST00000373087.6
zinc finger CCCH-type containing 12A
chr1_+_26438289 0.15 ENST00000374271.4
ENST00000374269.1
PDLIM1 interacting kinase 1 like
chr15_+_89181974 0.15 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr1_-_146644122 0.15 ENST00000254101.3
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr2_-_65357225 0.15 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A, member RAS oncogene family
chr5_+_133562095 0.15 ENST00000602919.1
CTD-2410N18.3
chr9_+_107509944 0.15 ENST00000374767.4
nipsnap homolog 3A (C. elegans)
chr5_-_94620239 0.15 ENST00000515393.1
multiple C2 domains, transmembrane 1
chr11_+_93861993 0.15 ENST00000227638.3
ENST00000436171.2
pannexin 1
chr17_-_6543973 0.15 ENST00000571642.1
ENST00000572370.1
KIAA0753
chr17_+_67498295 0.15 ENST00000589295.1
mitogen-activated protein kinase kinase 6
chr7_+_129710350 0.15 ENST00000335420.5
ENST00000463413.1
kelch domain containing 10
chr1_+_219347186 0.15 ENST00000366928.5
lysophospholipase-like 1
chrX_-_47004878 0.15 ENST00000377811.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr2_-_179315490 0.15 ENST00000487082.1
protein kinase, interferon-inducible double stranded RNA dependent activator
chr8_+_81397876 0.15 ENST00000430430.1
zinc finger and BTB domain containing 10
chr1_+_113217073 0.15 ENST00000369645.1
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr7_+_106809406 0.15 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HMG-box transcription factor 1
chr16_+_3162557 0.15 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
zinc finger protein 205
chr5_+_32531893 0.14 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr3_-_128840604 0.14 ENST00000476465.1
ENST00000315150.5
ENST00000393304.1
ENST00000393308.1
ENST00000393307.1
ENST00000393305.1
RAB43, member RAS oncogene family
chr4_-_74964904 0.14 ENST00000508487.2
chemokine (C-X-C motif) ligand 2
chr15_+_43622843 0.14 ENST00000428046.3
ENST00000422466.2
ENST00000389651.4
adenosine deaminase-like
chr1_-_207095212 0.14 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr4_-_169931231 0.14 ENST00000504561.1
carbonyl reductase 4
chr1_-_196577489 0.14 ENST00000609185.1
ENST00000451324.2
ENST00000367433.5
ENST00000367431.4
potassium channel, subfamily T, member 2
chr9_-_38069208 0.14 ENST00000377707.3
ENST00000377700.4
Src homology 2 domain containing adaptor protein B

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.5 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.5 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.8 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.4 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.8 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.3 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.2 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.2 GO:2000627 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.1 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.2 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.4 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.5 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.1 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.1 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0070377 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.3 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 1.1 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.3 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.0 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.3 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.1 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.3 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.4 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0044597 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:0072554 blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:1904685 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0006231 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.3 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.6 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.4 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.3 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.5 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.2 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.0 0.1 GO:0004132 dCMP deaminase activity(GO:0004132)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.0 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 2.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism