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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for EGR3_EGR2

Z-value: 0.88

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Transcription factors associated with EGR3_EGR2

Gene Symbol Gene ID Gene Info
ENSG00000179388.8 early growth response 3
ENSG00000122877.9 early growth response 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR3hg19_v2_chr8_-_22550815_22550844-0.972.6e-02Click!
EGR2hg19_v2_chr10_-_64576105_64576133-0.928.5e-02Click!

Activity profile of EGR3_EGR2 motif

Sorted Z-values of EGR3_EGR2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_176924562 1.40 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
PDZ and LIM domain 7 (enigma)
chr19_-_49371711 1.19 ENST00000355496.5
ENST00000263265.6
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr19_+_39786962 1.02 ENST00000333625.2
interferon, lambda 1
chrX_-_48814810 0.66 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTU domain containing 5
chr2_+_220306745 0.63 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG complex locus
chr19_+_47778119 0.62 ENST00000552360.2
proline rich 24
chr7_-_100493482 0.59 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
acetylcholinesterase (Yt blood group)
chr1_+_161494036 0.58 ENST00000309758.4
heat shock 70kDa protein 6 (HSP70B')
chrX_-_48814278 0.56 ENST00000455452.1
OTU domain containing 5
chr8_+_145321517 0.54 ENST00000340210.1
scleraxis homolog B (mouse)
chr3_-_88108212 0.51 ENST00000482016.1
CGG triplet repeat binding protein 1
chr15_-_71146460 0.50 ENST00000344870.4
La ribonucleoprotein domain family, member 6
chr19_+_10400615 0.49 ENST00000221980.4
intercellular adhesion molecule 5, telencephalin
chr12_+_70760056 0.48 ENST00000258111.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr16_+_3070313 0.48 ENST00000326577.4
tumor necrosis factor receptor superfamily, member 12A
chr22_-_30722912 0.44 ENST00000215790.7
TBC1 domain family, member 10A
chr2_-_27718052 0.44 ENST00000264703.3
fibronectin type III domain containing 4
chr19_-_13617037 0.42 ENST00000360228.5
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr19_+_10197463 0.40 ENST00000590378.1
ENST00000397881.3
chromosome 19 open reading frame 66
chr14_-_69445793 0.40 ENST00000538545.2
ENST00000394419.4
actinin, alpha 1
chr6_+_138188351 0.40 ENST00000421450.1
tumor necrosis factor, alpha-induced protein 3
chr7_+_100770328 0.38 ENST00000223095.4
ENST00000445463.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr16_+_3070356 0.38 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
tumor necrosis factor receptor superfamily, member 12A
chr2_+_191513587 0.37 ENST00000416973.1
ENST00000426601.1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr14_-_69445968 0.37 ENST00000438964.2
actinin, alpha 1
chr1_-_9189229 0.36 ENST00000377411.4
G protein-coupled receptor 157
chr22_-_30722866 0.35 ENST00000403477.3
TBC1 domain family, member 10A
chr20_-_3996165 0.35 ENST00000545616.2
ENST00000358395.6
ring finger protein 24
chrX_+_133930798 0.34 ENST00000414371.2
family with sequence similarity 122C
chr20_+_49348081 0.33 ENST00000371610.2
par-6 family cell polarity regulator beta
chr5_-_176923803 0.33 ENST00000506161.1
PDZ and LIM domain 7 (enigma)
chr19_-_54693521 0.32 ENST00000391754.1
ENST00000245615.1
ENST00000431666.2
membrane bound O-acyltransferase domain containing 7
chr8_+_145490549 0.31 ENST00000340695.2
scleraxis homolog A (mouse)
chr12_-_54785074 0.31 ENST00000338010.5
ENST00000550774.1
zinc finger protein 385A
chr8_+_32405728 0.30 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
neuregulin 1
chr14_+_64971438 0.30 ENST00000555321.1
zinc finger and BTB domain containing 1
chr12_-_54785054 0.30 ENST00000352268.6
ENST00000549962.1
zinc finger protein 385A
chr9_-_131709858 0.29 ENST00000372586.3
dolichol kinase
chr19_-_54693401 0.29 ENST00000338624.6
membrane bound O-acyltransferase domain containing 7
chr17_+_72428266 0.29 ENST00000582473.1
G protein-coupled receptor, family C, group 5, member C
chr19_+_41107249 0.29 ENST00000396819.3
latent transforming growth factor beta binding protein 4
chr4_-_82393052 0.28 ENST00000335927.7
ENST00000504863.1
ENST00000264400.2
RasGEF domain family, member 1B
chr18_+_33877654 0.28 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
formin homology 2 domain containing 3
chr1_+_6845384 0.28 ENST00000303635.7
calmodulin binding transcription activator 1
chr3_-_49851313 0.27 ENST00000333486.3
ubiquitin-like modifier activating enzyme 7
chr14_-_69446034 0.27 ENST00000193403.6
actinin, alpha 1
chr16_-_2185899 0.27 ENST00000262304.4
ENST00000423118.1
polycystic kidney disease 1 (autosomal dominant)
chr1_-_16302608 0.26 ENST00000375743.4
ENST00000375733.2
zinc finger and BTB domain containing 17
chr11_-_64512803 0.26 ENST00000377489.1
ENST00000354024.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_+_589893 0.26 ENST00000251287.2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr8_-_139926236 0.26 ENST00000303045.6
ENST00000435777.1
collagen, type XXII, alpha 1
chr11_+_124609823 0.26 ENST00000412681.2
neurogranin (protein kinase C substrate, RC3)
chr10_-_101380121 0.25 ENST00000370495.4
solute carrier family 25 (mitochondrial iron transporter), member 28
chr19_-_46145696 0.25 ENST00000588172.1
echinoderm microtubule associated protein like 2
chr2_+_155554797 0.24 ENST00000295101.2
potassium inwardly-rectifying channel, subfamily J, member 3
chr19_+_54412517 0.24 ENST00000391767.1
calcium channel, voltage-dependent, gamma subunit 7
chr15_-_75743991 0.24 ENST00000567289.1
SIN3 transcription regulator family member A
chr19_+_13906250 0.24 ENST00000254323.2
zinc finger, SWIM-type containing 4
chr15_+_74833518 0.24 ENST00000346246.5
AT rich interactive domain 3B (BRIGHT-like)
chr11_+_60699222 0.24 ENST00000536409.1
transmembrane protein 132A
chr1_-_154600421 0.24 ENST00000368471.3
ENST00000292205.5
adenosine deaminase, RNA-specific
chr16_-_2264779 0.23 ENST00000333503.7
phosphoglycolate phosphatase
chr15_-_41408409 0.23 ENST00000361937.3
INO80 complex subunit
chr15_-_80263506 0.23 ENST00000335661.6
BCL2-related protein A1
chr1_-_35395178 0.23 ENST00000373347.1
discs, large (Drosophila) homolog-associated protein 3
chr19_-_13617247 0.23 ENST00000573710.2
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr8_+_32405785 0.23 ENST00000287842.3
neuregulin 1
chr12_+_105724613 0.22 ENST00000549934.2
chromosome 12 open reading frame 75
chr3_-_50541028 0.22 ENST00000266039.3
ENST00000435965.1
ENST00000395083.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr2_-_191878874 0.21 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
signal transducer and activator of transcription 1, 91kDa
chr18_+_3449695 0.21 ENST00000343820.5
TGFB-induced factor homeobox 1
chr19_+_8455200 0.21 ENST00000601897.1
ENST00000594216.1
RAB11B, member RAS oncogene family
chrX_-_153200513 0.21 ENST00000432089.1
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr5_-_141030943 0.21 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCH and double SH3 domains 1
chrX_-_19905703 0.21 ENST00000397821.3
SH3-domain kinase binding protein 1
chr19_+_50180409 0.21 ENST00000391851.4
protein arginine methyltransferase 1
chr8_+_94929273 0.21 ENST00000518573.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr15_+_41221536 0.21 ENST00000249749.5
delta-like 4 (Drosophila)
chr2_-_128145498 0.21 ENST00000409179.2
mitogen-activated protein kinase kinase kinase 2
chr10_-_27444143 0.20 ENST00000477432.1
YME1-like 1 ATPase
chr5_-_176923846 0.20 ENST00000506537.1
PDZ and LIM domain 7 (enigma)
chr11_-_134095335 0.20 ENST00000534227.1
ENST00000532445.1
non-SMC condensin II complex, subunit D3
chr8_-_57123815 0.20 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
pleiomorphic adenoma gene 1
chr19_-_51568324 0.20 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
kallikrein-related peptidase 13
chr19_-_49622348 0.20 ENST00000408991.2
chromosome 19 open reading frame 73
chr2_-_191878681 0.20 ENST00000409465.1
signal transducer and activator of transcription 1, 91kDa
chr6_+_99282570 0.20 ENST00000328345.5
POU class 3 homeobox 2
chr2_+_23608064 0.20 ENST00000486442.1
kelch-like family member 29
chr20_-_17662878 0.20 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
ribosome binding protein 1
chr1_-_16302565 0.19 ENST00000537142.1
ENST00000448462.2
zinc finger and BTB domain containing 17
chr14_+_23352374 0.19 ENST00000267396.4
ENST00000536884.1
RAS (RAD and GEM)-like GTP binding 2
chr20_+_49348109 0.19 ENST00000396039.1
par-6 family cell polarity regulator beta
chr8_+_32406179 0.19 ENST00000405005.3
neuregulin 1
chr17_+_7210898 0.19 ENST00000572815.1
eukaryotic translation initiation factor 5A
chr19_-_12845550 0.19 ENST00000242784.4
chromosome 19 open reading frame 43
chr1_+_26606608 0.19 ENST00000319041.6
SH3 domain binding glutamic acid-rich protein like 3
chr20_+_34894247 0.19 ENST00000373913.3
discs, large (Drosophila) homolog-associated protein 4
chr3_+_38179969 0.18 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
myeloid differentiation primary response 88
chr19_-_12845467 0.18 ENST00000592273.1
ENST00000588213.1
chromosome 19 open reading frame 43
chr16_+_50582222 0.18 ENST00000268459.3
naked cuticle homolog 1 (Drosophila)
chr19_+_16940198 0.18 ENST00000248054.5
ENST00000596802.1
ENST00000379803.1
SIN3 transcription regulator family member B
chr17_+_72428218 0.18 ENST00000392628.2
G protein-coupled receptor, family C, group 5, member C
chr2_-_86116020 0.18 ENST00000525834.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr14_+_91526668 0.18 ENST00000521334.1
chromosome 14 open reading frame 159
chr9_-_130693048 0.18 ENST00000388747.4
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr6_-_4135825 0.18 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
enoyl-CoA delta isomerase 2
chr19_+_49617581 0.18 ENST00000391864.3
lin-7 homolog B (C. elegans)
chr9_-_132515302 0.18 ENST00000340607.4
prostaglandin E synthase
chr22_-_30970498 0.18 ENST00000431313.1
galactose-3-O-sulfotransferase 1
chr3_+_10206545 0.18 ENST00000256458.4
interleukin-1 receptor-associated kinase 2
chr7_-_100808394 0.18 ENST00000445482.2
VGF nerve growth factor inducible
chr6_+_144471643 0.18 ENST00000367568.4
syntaxin 11
chr12_-_7125770 0.18 ENST00000261407.4
lysophosphatidylcholine acyltransferase 3
chr11_-_65640198 0.18 ENST00000528176.1
EGF containing fibulin-like extracellular matrix protein 2
chr11_+_64009072 0.18 ENST00000535135.1
ENST00000394540.3
FK506 binding protein 2, 13kDa
chr1_+_41157671 0.18 ENST00000534399.1
ENST00000372653.1
nuclear transcription factor Y, gamma
chr16_+_69139467 0.18 ENST00000569188.1
hyaluronan synthase 3
chr11_-_33183048 0.18 ENST00000438862.2
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr16_+_2564254 0.17 ENST00000565223.1
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr14_-_64971288 0.17 ENST00000394715.1
zinc finger and BTB domain containing 25
chr11_-_65325430 0.17 ENST00000322147.4
latent transforming growth factor beta binding protein 3
chr6_+_134274354 0.17 ENST00000367869.1
TBP-like 1
chr20_-_3996036 0.17 ENST00000336095.6
ring finger protein 24
chr6_+_138188551 0.17 ENST00000237289.4
ENST00000433680.1
tumor necrosis factor, alpha-induced protein 3
chr17_-_36760865 0.17 ENST00000584266.1
SRC kinase signaling inhibitor 1
chr17_-_56609302 0.17 ENST00000581607.1
ENST00000317256.6
ENST00000426861.1
ENST00000580809.1
ENST00000577729.1
ENST00000583291.1
septin 4
chr1_+_113217309 0.17 ENST00000544796.1
ENST00000369644.1
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr9_+_19049372 0.16 ENST00000380527.1
Ras-related GTP binding A
chr1_+_43148625 0.16 ENST00000436427.1
Y box binding protein 1
chr5_-_38845812 0.16 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1
chr3_+_101546827 0.16 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr2_+_177001685 0.16 ENST00000432796.2
homeobox D3
chr12_+_6875519 0.16 ENST00000389462.4
ENST00000540874.1
ENST00000309083.6
parathymosin
chr7_-_100808843 0.16 ENST00000249330.2
VGF nerve growth factor inducible
chr6_-_127840048 0.16 ENST00000467753.1
SOGA family member 3
chr19_-_663277 0.16 ENST00000292363.5
ring finger protein 126
chr19_+_51815102 0.16 ENST00000270642.8
IgLON family member 5
chr16_-_30134524 0.16 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
mitogen-activated protein kinase 3
chr17_+_47865917 0.16 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
K(lysine) acetyltransferase 7
chr3_-_50540854 0.16 ENST00000423994.2
ENST00000424201.2
ENST00000479441.1
ENST00000429770.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr18_+_3449821 0.16 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGFB-induced factor homeobox 1
chr1_-_161087802 0.16 ENST00000368010.3
prefoldin subunit 2
chr1_+_43148059 0.16 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr6_-_37665751 0.16 ENST00000297153.7
ENST00000434837.3
MAM domain containing glycosylphosphatidylinositol anchor 1
chr15_-_71146347 0.16 ENST00000559140.2
La ribonucleoprotein domain family, member 6
chr19_-_663171 0.16 ENST00000606896.1
ENST00000589762.2
ring finger protein 126
chr4_+_8201091 0.16 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3 domain and tetratricopeptide repeats 1
chr6_+_138188378 0.16 ENST00000420009.1
tumor necrosis factor, alpha-induced protein 3
chr11_-_64545941 0.16 ENST00000377387.1
splicing factor 1
chr14_-_21737551 0.16 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr7_+_129074266 0.16 ENST00000249344.2
ENST00000435494.2
striatin interacting protein 2
chr19_-_663147 0.15 ENST00000606702.1
ring finger protein 126
chr10_+_6625605 0.15 ENST00000414894.1
ENST00000449648.1
PRKCQ antisense RNA 1
chr10_-_16859361 0.15 ENST00000377921.3
Ras suppressor protein 1
chr9_+_33025209 0.15 ENST00000330899.4
ENST00000544625.1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr19_-_6424783 0.15 ENST00000398148.3
KH-type splicing regulatory protein
chr7_-_93520191 0.15 ENST00000545378.1
tissue factor pathway inhibitor 2
chrX_+_47444613 0.15 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr3_+_32433363 0.15 ENST00000465248.1
CKLF-like MARVEL transmembrane domain containing 7
chr5_+_34656529 0.15 ENST00000513974.1
ENST00000512629.1
retinoic acid induced 14
chr22_+_19701985 0.15 ENST00000455784.2
ENST00000406395.1
septin 5
chr7_+_100199800 0.15 ENST00000223061.5
procollagen C-endopeptidase enhancer
chr7_-_93520259 0.15 ENST00000222543.5
tissue factor pathway inhibitor 2
chr16_+_2933187 0.15 ENST00000396958.3
FLYWCH family member 2
chr7_-_43909090 0.15 ENST00000317534.5
mitochondrial ribosomal protein S24
chr19_-_41859814 0.15 ENST00000221930.5
transforming growth factor, beta 1
chr5_+_34656331 0.15 ENST00000265109.3
retinoic acid induced 14
chr1_-_33502528 0.14 ENST00000354858.6
adenylate kinase 2
chr11_+_64685026 0.14 ENST00000526559.1
protein phosphatase 2, regulatory subunit B', beta
chr15_+_41136369 0.14 ENST00000563656.1
serine peptidase inhibitor, Kunitz type 1
chr14_-_23822080 0.14 ENST00000397267.1
ENST00000354772.3
solute carrier family 22, member 17
chr7_-_130080681 0.14 ENST00000469826.1
centrosomal protein 41kDa
chr19_+_35634146 0.14 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD domain containing ion transport regulator 7
chr5_+_14143728 0.14 ENST00000344204.4
ENST00000537187.1
trio Rho guanine nucleotide exchange factor
chr19_+_45504688 0.14 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr10_+_27444268 0.14 ENST00000375940.4
ENST00000342386.6
microtubule associated serine/threonine kinase-like
chr18_-_51750948 0.14 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr17_-_62502639 0.14 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr5_+_52285144 0.14 ENST00000296585.5
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr14_-_21737610 0.14 ENST00000320084.7
ENST00000449098.1
ENST00000336053.6
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr13_-_45151259 0.14 ENST00000493016.1
TSC22 domain family, member 1
chr10_-_13043697 0.14 ENST00000378825.3
coiled-coil domain containing 3
chr5_-_176037105 0.14 ENST00000303991.4
G protein regulated inducer of neurite outgrowth 1
chr10_-_16859442 0.14 ENST00000602389.1
ENST00000345264.5
Ras suppressor protein 1
chr11_-_65325664 0.14 ENST00000301873.5
latent transforming growth factor beta binding protein 3
chr2_-_202645612 0.14 ENST00000409632.2
ENST00000410052.1
ENST00000467448.1
amyotrophic lateral sclerosis 2 (juvenile)
chr4_-_83295296 0.13 ENST00000507010.1
ENST00000503822.1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr16_+_31044812 0.13 ENST00000313843.3
syntaxin 4
chr12_-_69080590 0.13 ENST00000433116.2
ENST00000500695.2
RP11-637A17.2
chrX_+_107069063 0.13 ENST00000262843.6
midline 2
chr19_-_18548921 0.13 ENST00000545187.1
ENST00000578352.1
inositol-3-phosphate synthase 1
chr1_+_185126598 0.13 ENST00000450350.1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr19_-_55770311 0.13 ENST00000412770.2
protein phosphatase 6, regulatory subunit 1
chrX_+_117957741 0.13 ENST00000310164.2
zinc finger, CCHC domain containing 12
chr19_+_11071546 0.13 ENST00000358026.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr1_+_113217043 0.13 ENST00000413052.2
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr19_-_10530784 0.13 ENST00000593124.1
cell division cycle 37
chr19_-_18548962 0.13 ENST00000317018.6
ENST00000581800.1
ENST00000583534.1
ENST00000457269.4
ENST00000338128.8
inositol-3-phosphate synthase 1
chr19_+_4007644 0.13 ENST00000262971.2
protein inhibitor of activated STAT, 4
chr12_+_105724414 0.13 ENST00000443585.1
ENST00000552457.1
ENST00000549893.1
chromosome 12 open reading frame 75

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR3_EGR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.2 0.7 GO:2000349 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.2 0.7 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 0.5 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.1 0.4 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.3 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.4 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.6 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.3 GO:1990828 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.1 0.9 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.3 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.7 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.3 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.5 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.2 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.4 GO:1902460 mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.3 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.3 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.1 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:1903911 positive regulation of receptor clustering(GO:1903911)
0.1 0.2 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.2 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.1 0.2 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.3 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.6 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.1 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.3 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.0 0.2 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.1 GO:2001112 negative regulation of hepatocyte growth factor receptor signaling pathway(GO:1902203) regulation of cellular response to hepatocyte growth factor stimulus(GO:2001112) negative regulation of cellular response to hepatocyte growth factor stimulus(GO:2001113)
0.0 0.2 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.3 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 1.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.3 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.0 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.0 GO:0098907 regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.4 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.3 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.0 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0060927 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.0 0.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.6 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.1 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.2 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 2.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0072302 negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) negative regulation of glomerulus development(GO:0090194)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.1 GO:0090340 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.0 0.0 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.0 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.0 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0007135 meiosis II(GO:0007135)
0.0 0.0 GO:0060592 mammary gland formation(GO:0060592)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:1903309 negative regulation of chromatin modification(GO:1903309)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.0 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.0 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.2 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0002192 IRES-dependent translational initiation(GO:0002192)
0.0 0.0 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.4 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.6 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.0 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.0 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.0 GO:0043449 pons maturation(GO:0021586) cellular alkene metabolic process(GO:0043449)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.3 GO:0002021 response to dietary excess(GO:0002021)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.2 GO:0000806 Y chromosome(GO:0000806)
0.1 1.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0002133 polycystin complex(GO:0002133)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.0 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.0 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.0 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 1.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.2 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.3 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.5 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.4 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.0 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.1 GO:0010736 serum response element binding(GO:0010736)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.0 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.0 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 2.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.0 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects