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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for EBF3
Z-value: 1.54
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Transcription factors associated with EBF3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EBF3 | hg19_v2_chr10_-_131762105_131762105 | -0.04 | 9.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_-_62203808 Show fit | 0.94 |
ENST00000467148.1
|
helicase with zinc finger 2, transcriptional coactivator |
|
| chr12_-_112546547 Show fit | 0.93 |
ENST00000547133.1
|
N(alpha)-acetyltransferase 25, NatB auxiliary subunit |
|
| chr18_-_19748379 Show fit | 0.79 |
ENST00000579431.1
|
GATA6 antisense RNA 1 (head to head) |
|
| chr2_+_220325977 Show fit | 0.79 |
ENST00000396686.1
ENST00000396689.2 |
SPEG complex locus |
|
| chr19_-_38743878 Show fit | 0.72 |
ENST00000587515.1
|
protein phosphatase 1, regulatory (inhibitor) subunit 14A |
|
| chr12_+_7072354 Show fit | 0.70 |
ENST00000537269.1
|
U47924.27 |
|
| chr1_+_153330322 Show fit | 0.69 |
ENST00000368738.3
|
S100 calcium binding protein A9 |
|
| chr2_+_220325441 Show fit | 0.63 |
ENST00000396688.1
|
SPEG complex locus |
|
| chr4_+_7194247 Show fit | 0.63 |
ENST00000507866.2
|
sortilin-related VPS10 domain containing receptor 2 |
|
| chr17_-_43045439 Show fit | 0.61 |
ENST00000253407.3
|
complement component 1, q subcomponent-like 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of EBF3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.1 | 0.9 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 0.8 | GO:2000860 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.2 | 0.7 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.1 | 0.7 | GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) |
| 0.2 | 0.6 | GO:0061743 | motor learning(GO:0061743) maintenance of synapse structure(GO:0099558) |
| 0.1 | 0.6 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274) |
| 0.1 | 0.6 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.0 | 0.6 | GO:0060180 | female mating behavior(GO:0060180) |
| 0.0 | 0.6 | GO:0060242 | contact inhibition(GO:0060242) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 0.9 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.2 | 0.6 | GO:0044301 | climbing fiber(GO:0044301) |
| 0.1 | 0.6 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.0 | 0.6 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.6 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.6 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 0.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 0.5 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 0.5 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 0.9 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.9 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 0.7 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.0 | 0.7 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 0.6 | GO:0042806 | fucose binding(GO:0042806) |
| 0.1 | 0.6 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.0 | 0.6 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 0.5 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.0 | 0.5 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 1.0 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.4 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.4 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 0.3 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.0 | 0.3 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.2 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 0.9 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.6 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 0.5 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.0 | 0.4 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.0 | 0.4 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.3 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.3 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 0.3 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.3 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |