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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for E2F2_E2F5

Z-value: 3.60

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Transcription factors associated with E2F2_E2F5

Gene Symbol Gene ID Gene Info
ENSG00000007968.6 E2F transcription factor 2
ENSG00000133740.6 E2F transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F2hg19_v2_chr1_-_23857698_238577330.955.0e-02Click!
E2F5hg19_v2_chr8_+_86089619_860896530.653.5e-01Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_62538248 4.37 ENST00000448257.2
cyclin-dependent kinase 1
chr10_+_62538089 3.57 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr15_-_64673630 3.05 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr15_+_32907691 2.84 ENST00000361627.3
ENST00000567348.1
ENST00000563864.1
ENST00000543522.1
Rho GTPase activating protein 11A
chr5_-_79950775 2.82 ENST00000439211.2
dihydrofolate reductase
chr11_+_47236489 2.76 ENST00000256996.4
ENST00000378603.3
ENST00000378600.3
ENST00000378601.3
damage-specific DNA binding protein 2, 48kDa
chr15_-_64673665 2.70 ENST00000300035.4
KIAA0101
chr1_-_36235529 2.54 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
claspin
chr2_+_17935119 2.44 ENST00000317402.7
GEN1 Holliday junction 5' flap endonuclease
chr8_-_120868078 2.32 ENST00000313655.4
DNA replication and sister chromatid cohesion 1
chrX_+_123095546 2.12 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
stromal antigen 2
chr1_-_23857698 2.06 ENST00000361729.2
E2F transcription factor 2
chr2_+_174219548 2.03 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
cell division cycle associated 7
chr1_-_26232522 2.01 ENST00000399728.1
stathmin 1
chr4_+_154265784 1.91 ENST00000240488.3
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr10_+_112327425 1.81 ENST00000361804.4
structural maintenance of chromosomes 3
chr20_-_32274179 1.79 ENST00000343380.5
E2F transcription factor 1
chr19_+_36705504 1.78 ENST00000456324.1
zinc finger protein 146
chr9_-_35079911 1.75 ENST00000448890.1
Fanconi anemia, complementation group G
chr1_+_25598872 1.68 ENST00000328664.4
Rh blood group, D antigen
chr10_+_103911926 1.68 ENST00000605788.1
ENST00000405356.1
nucleolar and coiled-body phosphoprotein 1
chr1_+_212782012 1.67 ENST00000341491.4
ENST00000366985.1
activating transcription factor 3
chr19_+_36706024 1.66 ENST00000443387.2
zinc finger protein 146
chr14_+_74551650 1.61 ENST00000554938.1
lin-52 homolog (C. elegans)
chr5_-_79950371 1.54 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
dihydrofolate reductase
chr6_-_132272504 1.53 ENST00000367976.3
connective tissue growth factor
chr3_+_44803209 1.51 ENST00000326047.4
kinesin family member 15
chr19_-_36705763 1.48 ENST00000591473.1
zinc finger protein 565
chr17_+_29158962 1.42 ENST00000321990.4
ATPase family, AAA domain containing 5
chr5_-_176738883 1.38 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
MAX dimerization protein 3
chr14_+_36295638 1.38 ENST00000543183.1
breast cancer metastasis-suppressor 1-like
chrX_+_123095860 1.38 ENST00000428941.1
stromal antigen 2
chr13_-_110438914 1.37 ENST00000375856.3
insulin receptor substrate 2
chr20_+_25388293 1.36 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr10_+_103912137 1.33 ENST00000603742.1
ENST00000488254.2
ENST00000461421.1
ENST00000476468.1
ENST00000370007.5
nucleolar and coiled-body phosphoprotein 1
chrX_+_123095890 1.30 ENST00000435215.1
stromal antigen 2
chr1_-_26232951 1.30 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr9_-_99180597 1.30 ENST00000375256.4
zinc finger protein 367
chr10_+_96305535 1.29 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
helicase, lymphoid-specific
chr7_+_94285637 1.28 ENST00000482108.1
ENST00000488574.1
paternally expressed 10
chr3_+_16926441 1.27 ENST00000418129.2
ENST00000396755.2
phospholipase C-like 2
chr6_-_27806117 1.26 ENST00000330180.2
histone cluster 1, H2ak
chr2_+_17935383 1.21 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr7_-_158497431 1.20 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
non-SMC condensin II complex, subunit G2
chr11_+_9595180 1.16 ENST00000450114.2
WEE1 G2 checkpoint kinase
chr1_-_36235559 1.16 ENST00000251195.5
claspin
chr7_+_26241310 1.15 ENST00000396386.2
chromobox homolog 3
chr3_-_14220068 1.13 ENST00000449060.2
ENST00000511155.1
xeroderma pigmentosum, complementation group C
chr1_+_228645796 1.12 ENST00000369160.2
histone cluster 3, H2bb
chr1_-_26233423 1.12 ENST00000357865.2
stathmin 1
chr7_+_139044621 1.11 ENST00000354926.4
C7orf55-LUC7L2 readthrough
chr6_+_26225354 1.01 ENST00000360408.1
histone cluster 1, H3e
chr13_+_45694583 1.01 ENST00000340473.6
general transcription factor IIF, polypeptide 2, 30kDa
chr4_+_129731074 1.01 ENST00000512960.1
ENST00000503785.1
ENST00000514740.1
jade family PHD finger 1
chr15_+_40987327 1.00 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51 recombinase
chr16_-_10674528 0.99 ENST00000359543.3
epithelial membrane protein 2
chr6_-_30181156 0.97 ENST00000418026.1
ENST00000416596.1
ENST00000453195.1
tripartite motif containing 26
chr4_+_129730839 0.97 ENST00000511647.1
jade family PHD finger 1
chr4_+_129730947 0.96 ENST00000452328.2
ENST00000504089.1
jade family PHD finger 1
chr7_+_26241325 0.96 ENST00000456948.1
ENST00000409747.1
chromobox homolog 3
chr14_-_50154921 0.93 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
polymerase (DNA directed), epsilon 2, accessory subunit
chr20_-_35724388 0.91 ENST00000344359.3
ENST00000373664.3
retinoblastoma-like 1 (p107)
chr4_+_178230985 0.90 ENST00000264596.3
nei endonuclease VIII-like 3 (E. coli)
chr3_-_136471204 0.90 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
stromal antigen 1
chr4_+_72052964 0.89 ENST00000264485.5
ENST00000425175.1
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr6_-_30181133 0.89 ENST00000454678.2
ENST00000434785.1
tripartite motif containing 26
chrX_+_101906294 0.89 ENST00000361600.5
ENST00000415986.1
ENST00000444152.1
ENST00000537097.1
G protein-coupled receptor associated sorting protein 1
chr1_+_179262905 0.88 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
sterol O-acyltransferase 1
chr2_-_17935059 0.88 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
structural maintenance of chromosomes 6
chr7_-_94285511 0.87 ENST00000265735.7
sarcoglycan, epsilon
chr7_-_94285472 0.86 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
sarcoglycan, epsilon
chr19_-_6502341 0.86 ENST00000598006.1
ENST00000601152.1
tubulin, beta 4A class IVa
chr11_+_125495862 0.86 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
checkpoint kinase 1
chr7_+_86781847 0.85 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
cyclin D binding myb-like transcription factor 1
chr2_+_48010221 0.85 ENST00000234420.5
mutS homolog 6
chr14_+_36295504 0.85 ENST00000216807.7
breast cancer metastasis-suppressor 1-like
chr16_-_3030407 0.81 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
protein kinase, membrane associated tyrosine/threonine 1
chr5_+_36152163 0.81 ENST00000274255.6
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr10_-_58120996 0.81 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZW10 interacting kinetochore protein
chr4_+_71859156 0.80 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
deoxycytidine kinase
chr22_-_38966123 0.79 ENST00000439567.1
DNA meiotic recombinase 1
chr7_+_26240776 0.79 ENST00000337620.4
chromobox homolog 3
chrX_+_48554986 0.79 ENST00000376687.3
ENST00000453214.2
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr9_+_106856541 0.77 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
structural maintenance of chromosomes 2
chr10_-_25241499 0.77 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
phosphoribosyl transferase domain containing 1
chr13_-_41768654 0.77 ENST00000379483.3
kelch repeat and BTB (POZ) domain containing 7
chr9_-_123639445 0.76 ENST00000312189.6
PHD finger protein 19
chr1_+_179263308 0.75 ENST00000426956.1
sterol O-acyltransferase 1
chr2_+_48010312 0.74 ENST00000540021.1
mutS homolog 6
chr4_+_129730779 0.73 ENST00000226319.6
jade family PHD finger 1
chr6_-_27100529 0.72 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
histone cluster 1, H2bj
chr20_-_5100591 0.72 ENST00000379143.5
proliferating cell nuclear antigen
chr14_-_74551096 0.71 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr12_-_77459306 0.71 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F transcription factor 7
chr9_-_123639304 0.71 ENST00000436309.1
PHD finger protein 19
chr12_-_12849073 0.71 ENST00000332427.2
ENST00000540796.1
G protein-coupled receptor 19
chr17_+_42733803 0.70 ENST00000409122.2
chromosome 17 open reading frame 104
chr7_-_94285402 0.70 ENST00000428696.2
ENST00000445866.2
sarcoglycan, epsilon
chr14_+_35452169 0.70 ENST00000555557.1
signal recognition particle 54kDa
chr20_+_5931275 0.70 ENST00000378896.3
ENST00000378883.1
minichromosome maintenance complex component 8
chr13_-_73356009 0.69 ENST00000377780.4
ENST00000377767.4
DIS3 mitotic control homolog (S. cerevisiae)
chr15_+_71184931 0.69 ENST00000560369.1
ENST00000260382.5
leucine rich repeat containing 49
chr19_+_19144666 0.69 ENST00000535288.1
ENST00000538663.1
armadillo repeat containing 6
chr11_+_74303575 0.68 ENST00000263681.2
polymerase (DNA-directed), delta 3, accessory subunit
chr2_-_55277692 0.68 ENST00000394611.2
reticulon 4
chr1_-_221915418 0.67 ENST00000323825.3
ENST00000366899.3
dual specificity phosphatase 10
chrX_+_24711997 0.67 ENST00000379068.3
ENST00000379059.3
polymerase (DNA directed), alpha 1, catalytic subunit
chr6_-_116575226 0.66 ENST00000420283.1
TSPY-like 4
chr16_+_58426296 0.66 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
GINS complex subunit 3 (Psf3 homolog)
chr9_-_35080013 0.66 ENST00000378643.3
Fanconi anemia, complementation group G
chr3_+_10068095 0.66 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr5_+_56469843 0.65 ENST00000514387.2
GC-rich promoter binding protein 1
chr6_+_35995531 0.65 ENST00000229794.4
mitogen-activated protein kinase 14
chr1_+_100598691 0.64 ENST00000370143.1
ENST00000370141.2
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr19_+_16187085 0.64 ENST00000300933.4
tropomyosin 4
chr22_-_41864662 0.64 ENST00000216252.3
PHD finger protein 5A
chr16_+_28962128 0.64 ENST00000564978.1
ENST00000320805.4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr5_+_79950463 0.64 ENST00000265081.6
mutS homolog 3
chr8_-_125740730 0.64 ENST00000354184.4
metastasis suppressor 1
chr10_+_13203543 0.63 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
minichromosome maintenance complex component 10
chr14_+_35452104 0.63 ENST00000216774.6
ENST00000546080.1
signal recognition particle 54kDa
chr16_-_3030283 0.61 ENST00000572619.1
ENST00000574415.1
ENST00000440027.2
ENST00000572059.1
protein kinase, membrane associated tyrosine/threonine 1
chr10_+_73724123 0.61 ENST00000373115.4
carbohydrate (chondroitin 6) sulfotransferase 3
chr14_-_74551172 0.61 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr19_+_19144384 0.61 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr16_+_47495225 0.61 ENST00000299167.8
ENST00000323584.5
ENST00000563376.1
phosphorylase kinase, beta
chr17_+_58677539 0.59 ENST00000305921.3
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr8_-_125740514 0.59 ENST00000325064.5
ENST00000518547.1
metastasis suppressor 1
chr12_+_133264156 0.58 ENST00000317479.3
ENST00000543589.1
peroxisomal membrane protein 2, 22kDa
chr6_+_35995488 0.57 ENST00000229795.3
mitogen-activated protein kinase 14
chr16_+_29817399 0.57 ENST00000545521.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_-_100026280 0.56 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
zinc finger, CW type with PWWP domain 1
chr2_+_170440902 0.55 ENST00000448752.2
ENST00000418888.1
ENST00000414307.1
peptidylprolyl isomerase G (cyclophilin G)
chr17_-_77179487 0.54 ENST00000580508.1
RNA binding protein, fox-1 homolog (C. elegans) 3
chr10_+_96305610 0.54 ENST00000371332.4
ENST00000239026.6
helicase, lymphoid-specific
chr15_+_71185148 0.54 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr16_+_47495201 0.54 ENST00000566044.1
ENST00000455779.1
phosphorylase kinase, beta
chr12_-_133263893 0.53 ENST00000535270.1
ENST00000320574.5
polymerase (DNA directed), epsilon, catalytic subunit
chr1_-_229694406 0.53 ENST00000344517.4
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chrX_+_100353153 0.53 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
centromere protein I
chr9_-_120177216 0.53 ENST00000373996.3
ENST00000313400.4
ENST00000361477.3
astrotactin 2
chr10_+_70587279 0.52 ENST00000298596.6
ENST00000399169.4
ENST00000399165.4
ENST00000399162.2
storkhead box 1
chr9_+_106856831 0.52 ENST00000303219.8
ENST00000374787.3
structural maintenance of chromosomes 2
chr1_+_222885884 0.52 ENST00000340934.5
BRO1 domain and CAAX motif containing
chr6_-_35656712 0.52 ENST00000357266.4
ENST00000542713.1
FK506 binding protein 5
chr2_+_10263298 0.52 ENST00000474701.1
ribonucleotide reductase M2
chr11_+_4116054 0.51 ENST00000423050.2
ribonucleotide reductase M1
chr3_-_49893907 0.51 ENST00000482582.1
TRAF interacting protein
chr9_+_86595626 0.50 ENST00000445877.1
ENST00000325875.3
RecQ mediated genome instability 1
chr22_-_20104700 0.50 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr9_-_123639600 0.49 ENST00000373896.3
PHD finger protein 19
chr8_+_128748308 0.49 ENST00000377970.2
v-myc avian myelocytomatosis viral oncogene homolog
chr1_-_100598444 0.48 ENST00000535161.1
ENST00000287482.5
spindle assembly 6 homolog (C. elegans)
chr12_+_53848505 0.47 ENST00000552819.1
ENST00000455667.3
poly(rC) binding protein 2
chr3_-_133380731 0.47 ENST00000260810.5
topoisomerase (DNA) II binding protein 1
chr6_+_27100811 0.47 ENST00000359193.2
histone cluster 1, H2ag
chrX_-_152736013 0.46 ENST00000330912.2
ENST00000338525.2
ENST00000334497.2
ENST00000370232.1
ENST00000370212.3
ENST00000370211.4
three prime repair exonuclease 2
HAUS augmin-like complex, subunit 7
chrX_+_131157322 0.46 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chr6_-_27775694 0.46 ENST00000377401.2
histone cluster 1, H2bl
chr1_-_24306768 0.46 ENST00000374453.3
ENST00000453840.3
serine/arginine-rich splicing factor 10
chr6_-_144329531 0.45 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
pleiomorphic adenoma gene-like 1
chrX_-_62974941 0.44 ENST00000374872.1
ENST00000253401.6
ENST00000374870.4
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr3_+_10857885 0.44 ENST00000254488.2
ENST00000454147.1
solute carrier family 6 (neurotransmitter transporter), member 11
chr13_-_73301819 0.43 ENST00000377818.3
mitotic spindle organizing protein 1
chr5_+_56469939 0.43 ENST00000506184.2
GC-rich promoter binding protein 1
chr6_-_91296602 0.42 ENST00000369325.3
ENST00000369327.3
mitogen-activated protein kinase kinase kinase 7
chr16_-_85722530 0.42 ENST00000253462.3
GINS complex subunit 2 (Psf2 homolog)
chr2_+_170440844 0.42 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
peptidylprolyl isomerase G (cyclophilin G)
chr19_+_50432400 0.42 ENST00000423777.2
ENST00000600336.1
ENST00000597227.1
activating transcription factor 5
chr6_+_84569359 0.41 ENST00000369681.5
ENST00000369679.4
cytochrome b5 reductase 4
chrX_-_45710920 0.41 ENST00000456532.1
RP5-1158E12.3
chr9_+_17135016 0.40 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
centlein, centrosomal protein
chr7_+_86781677 0.40 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
cyclin D binding myb-like transcription factor 1
chr7_+_94139105 0.40 ENST00000297273.4
CAS1 domain containing 1
chr1_-_228645556 0.39 ENST00000366695.2
histone cluster 3, H2a
chr7_+_86781916 0.39 ENST00000579592.1
ENST00000434534.1
cyclin D binding myb-like transcription factor 1
chrX_-_53449593 0.39 ENST00000375340.6
ENST00000322213.4
structural maintenance of chromosomes 1A
chr4_-_174256276 0.38 ENST00000296503.5
high mobility group box 2
chrX_+_106871713 0.38 ENST00000372435.4
ENST00000372428.4
ENST00000372419.3
ENST00000543248.1
phosphoribosyl pyrophosphate synthetase 1
chr21_+_17961006 0.38 ENST00000602323.1
long intergenic non-protein coding RNA 478
chr12_-_51611477 0.38 ENST00000389243.4
POU class 6 homeobox 1
chr11_-_118966167 0.38 ENST00000530167.1
H2A histone family, member X
chr1_-_91487013 0.38 ENST00000347275.5
ENST00000370440.1
zinc finger protein 644
chr17_+_74734052 0.38 ENST00000590514.1
major facilitator superfamily domain containing 11
chr17_+_42733730 0.37 ENST00000359945.3
ENST00000425535.1
chromosome 17 open reading frame 104
chr4_-_130014532 0.36 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
sodium channel and clathrin linker 1
chr1_-_25747283 0.36 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
Rh blood group, CcEe antigens
chr17_+_38444115 0.36 ENST00000580824.1
ENST00000577249.1
cell division cycle 6
chr3_+_57261743 0.35 ENST00000288266.3
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr19_+_56653064 0.35 ENST00000593100.1
zinc finger protein 444
chr12_-_81331697 0.35 ENST00000552864.1
lin-7 homolog A (C. elegans)
chr6_+_35995552 0.35 ENST00000468133.1
mitogen-activated protein kinase 14
chr3_+_127317066 0.34 ENST00000265056.7
minichromosome maintenance complex component 2
chr1_+_233749739 0.34 ENST00000366621.3
potassium channel, subfamily K, member 1
chr2_-_55277654 0.34 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
reticulon 4
chr6_-_91296737 0.34 ENST00000369332.3
ENST00000369329.3
mitogen-activated protein kinase kinase kinase 7
chr21_-_30365136 0.33 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
listerin E3 ubiquitin protein ligase 1
chr12_-_31479045 0.33 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr7_-_27169801 0.33 ENST00000511914.1
homeobox A4
chr8_+_38089198 0.32 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.1 7.9 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
1.1 4.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.8 2.5 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.7 0.7 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.6 4.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.6 1.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5 1.6 GO:0000710 meiotic mismatch repair(GO:0000710)
0.5 2.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.5 1.5 GO:0034059 response to anoxia(GO:0034059)
0.5 7.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.5 1.9 GO:0006272 leading strand elongation(GO:0006272)
0.5 1.8 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.4 1.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.4 2.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 1.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.3 1.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.3 4.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 1.6 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.3 1.6 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.3 0.8 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.3 3.0 GO:0007000 nucleolus organization(GO:0007000)
0.2 2.8 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.2 0.2 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.7 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.2 1.2 GO:0030035 microspike assembly(GO:0030035) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2 0.5 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 0.8 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.9 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.9 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.7 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.4 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 2.0 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 1.4 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 1.4 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 1.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.7 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 1.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.4 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.9 GO:0042148 strand invasion(GO:0042148)
0.1 0.6 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.1 1.0 GO:0070836 caveola assembly(GO:0070836)
0.1 0.4 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.3 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.1 GO:0023035 CD40 signaling pathway(GO:0023035)
0.1 1.9 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.8 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.2 GO:0061010 external genitalia morphogenesis(GO:0035261) gall bladder development(GO:0061010)
0.1 0.9 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.6 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 2.4 GO:0015695 organic cation transport(GO:0015695)
0.1 0.5 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 1.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.4 GO:0060356 leucine import(GO:0060356)
0.1 0.2 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.5 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.1 1.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 2.0 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 1.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 1.1 GO:0006266 DNA ligation(GO:0006266)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.8 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.0 0.3 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.7 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 2.2 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.5 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.0 1.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 1.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.9 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.3 GO:0072422 signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 2.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.0 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 1.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 1.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.9 GO:0043550 regulation of lipid kinase activity(GO:0043550)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 7.9 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.6 0.6 GO:0032302 MutSbeta complex(GO:0032302)
0.6 1.8 GO:0035189 Rb-E2F complex(GO:0035189)
0.6 1.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.4 1.8 GO:0000811 GINS complex(GO:0000811)
0.4 1.6 GO:0005873 plus-end kinesin complex(GO:0005873)
0.3 1.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.3 1.6 GO:0032301 MutSalpha complex(GO:0032301)
0.3 3.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 1.8 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.3 2.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 1.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 0.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.1 GO:0071942 XPC complex(GO:0071942)
0.2 2.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 2.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 2.5 GO:0000796 condensin complex(GO:0000796)
0.2 0.9 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.2 1.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.4 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 1.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 1.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.8 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.9 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.2 GO:0033269 internode region of axon(GO:0033269)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.1 0.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 1.2 GO:0071439 clathrin complex(GO:0071439)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.2 GO:0031261 nuclear pre-replicative complex(GO:0005656) DNA replication preinitiation complex(GO:0031261) pre-replicative complex(GO:0036387)
0.1 2.6 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 1.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 2.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 3.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 7.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 3.0 GO:0000793 condensed chromosome(GO:0000793)
0.0 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0051870 methotrexate binding(GO:0051870)
0.6 2.4 GO:0036033 mediator complex binding(GO:0036033)
0.5 1.6 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.5 1.6 GO:0032142 single guanine insertion binding(GO:0032142) single thymine insertion binding(GO:0032143)
0.4 1.8 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.4 3.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.4 0.7 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.3 7.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 3.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.3 3.0 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 2.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 2.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.9 GO:0000405 bubble DNA binding(GO:0000405)
0.1 1.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 2.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.8 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.1 0.4 GO:0016768 spermine synthase activity(GO:0016768)
0.1 1.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 1.0 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.8 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.6 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 2.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.9 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 2.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.6 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.4 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 1.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 4.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 3.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 2.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 6.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 3.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.5 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 3.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 4.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.6 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 8.5 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.8 PID ATM PATHWAY ATM pathway
0.1 3.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 6.0 PID E2F PATHWAY E2F transcription factor network
0.0 3.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 4.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 2.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.4 5.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 5.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 1.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 2.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 4.8 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.1 10.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.9 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.1 1.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 3.4 REACTOME MEIOSIS Genes involved in Meiosis
0.1 0.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.7 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 2.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.6 REACTOME KINESINS Genes involved in Kinesins
0.0 1.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction