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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for CXXC1
Z-value: 2.80
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Transcription factors associated with CXXC1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CXXC1 | hg19_v2_chr18_-_47813940_47814021 | -0.93 | 7.1e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of CXXC1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.6 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.1 | 4.2 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 0.1 | 2.6 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.1 | 2.6 | GO:0097502 | mannosylation(GO:0097502) |
| 0.1 | 1.9 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.1 | 1.9 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.6 | 1.8 | GO:0034402 | recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402) |
| 0.1 | 1.8 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.0 | 1.8 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 1.7 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.4 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.2 | 3.2 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.1 | 2.2 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 2.2 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 2.0 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 2.0 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.3 | 1.9 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.0 | 1.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.5 | 1.6 | GO:0000818 | nuclear MIS12/MIND complex(GO:0000818) |
| 0.0 | 1.6 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.2 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 2.6 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 2.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.2 | 2.0 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.0 | 2.0 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 1.9 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 1.8 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.2 | 1.7 | GO:0004376 | glycolipid mannosyltransferase activity(GO:0004376) |
| 0.0 | 1.7 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 1.6 | GO:0050681 | androgen receptor binding(GO:0050681) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.0 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 2.2 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 2.2 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 1.8 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 1.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 1.3 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.0 | 1.3 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 1.2 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.1 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 4.2 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 3.6 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.0 | 2.3 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 2.2 | REACTOME VIRAL MESSENGER RNA SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.0 | 1.9 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.5 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 1.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 1.4 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 0.1 | 1.4 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |