ISMARA results: CEBPA

Project

A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for CEBPA

Z-value: 1.63

Motif logo

Transcription factors associated with CEBPA

Gene Symbol	Gene ID	Gene Info
CEBPA Ensembl NCBI GeneCards UniProt	ENSG00000245848.2	CCAAT enhancer binding protein alpha

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CEBPA	hg19_v2_chr19_-_33793430_33793470	-0.13	8.7e-01	Click!

Activity profile of CEBPA motif

Sorted Z-values of CEBPA motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr13_+_108921977 Show fit	2.13	ENST00000430559.1 ENST00000375887.4	TNFSF13B Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor (ligand) superfamily, member 13b
chr9_-_4859260 Show fit	1.64	ENST00000599351.1	AL158147.2 Ensembl NCBI GeneCards UniProt Show fit	HCG2011465; Uncharacterized protein
chr11_-_102668879 Show fit	1.43	ENST00000315274.6	MMP1 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 1 (interstitial collagenase)
chr11_+_107650219 Show fit	1.34	ENST00000398067.1	AP001024.1 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr3_-_148939598 Show fit	1.28	ENST00000455472.3	CP Ensembl NCBI GeneCards UniProt Show fit	ceruloplasmin (ferroxidase)
chr12_+_57810198 Show fit	1.03	ENST00000598001.1	AC126614.1 Ensembl NCBI GeneCards UniProt Show fit	HCG1818482; Uncharacterized protein
chr18_-_61329118 Show fit	0.87	ENST00000332821.8 ENST00000283752.5	SERPINB3 Ensembl NCBI GeneCards UniProt Show fit	serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr12_-_10007448 Show fit	0.77	ENST00000538152.1	CLEC2B Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 2, member B
chr15_-_55790515 Show fit	0.75	ENST00000448430.2 ENST00000457155.2	DYX1C1 Ensembl NCBI GeneCards UniProt Show fit	dyslexia susceptibility 1 candidate 1
chr18_-_61311485 Show fit	0.73	ENST00000436264.1 ENST00000356424.6 ENST00000341074.5	SERPINB4 Ensembl NCBI GeneCards UniProt Show fit	serpin peptidase inhibitor, clade B (ovalbumin), member 4

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPA

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.1	GO:0031296	B cell costimulation(GO:0031296)
0.0	1.4	GO:0006825	copper ion transport(GO:0006825)
0.0	1.1	GO:0090383	phagosome acidification(GO:0090383)
0.2	0.9	GO:0035425	autocrine signaling(GO:0035425)
0.1	0.9	GO:0035624	receptor transactivation(GO:0035624)
0.2	0.8	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.0	0.8	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.8	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.2	0.7	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2	0.7	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)

Showing 1 to 10 of 123 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	1.0	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	0.9	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2	0.7	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	0.7	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.1	0.5	GO:0031251	PAN complex(GO:0031251)
0.0	0.4	GO:0097452	GAIT complex(GO:0097452)
0.0	0.4	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.1	0.3	GO:0097486	multivesicular body lumen(GO:0097486)

Showing 1 to 10 of 29 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.0	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	2.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	1.4	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	1.2	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.9	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	0.8	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.8	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.2	0.7	GO:0004397	histidine ammonia-lyase activity(GO:0004397)
0.1	0.7	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.6	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)

Showing 1 to 10 of 85 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Total log-likelihood	Term	Description
1.5	PID FOXO PATHWAY	FoxO family signaling
1.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
1.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.7	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway

Showing 1 to 5 of 5 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.4	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.1	1.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.9	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.9	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.5	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement

Showing 1 to 10 of 15 entries

Results for CEBPA

Z-value: 1.63

Motif logo

Transcription factors associated with CEBPA

Activity-expression correlation:

Activity profile of CEBPA motif

Sorted Z-values of CEBPA motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPA

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: