ISMARA results: BPTF

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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for BPTF

Z-value: 1.16

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Transcription factors associated with BPTF

Gene Symbol	Gene ID	Gene Info
BPTF Ensembl NCBI GeneCards UniProt	ENSG00000171634.12	bromodomain PHD finger transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
BPTF	hg19_v2_chr17_+_65821636_65821641	0.76	2.4e-01	Click!

Activity profile of BPTF motif

Sorted Z-values of BPTF motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr22_-_37976082 Show fit	0.78	ENST00000215886.4	LGALS2 Ensembl NCBI GeneCards UniProt Show fit	lectin, galactoside-binding, soluble, 2
chr14_-_55658323 Show fit	0.68	ENST00000554067.1 ENST00000247191.2	DLGAP5 Ensembl NCBI GeneCards UniProt Show fit	discs, large (Drosophila) homolog-associated protein 5
chr4_-_74847800 Show fit	0.67	ENST00000296029.3	PF4 Ensembl NCBI GeneCards UniProt Show fit	platelet factor 4
chr5_+_82767583 Show fit	0.66	ENST00000512590.2 ENST00000513960.1 ENST00000513984.1 ENST00000502527.2	VCAN Ensembl NCBI GeneCards UniProt Show fit	versican
chr15_-_31521567 Show fit	0.55	ENST00000560812.1 ENST00000559853.1 ENST00000558109.1	RP11-16E12.2 Ensembl NCBI GeneCards UniProt Show fit	RP11-16E12.2
chr14_-_45722360 Show fit	0.51	ENST00000451174.1	MIS18BP1 Ensembl NCBI GeneCards UniProt Show fit	MIS18 binding protein 1
chr17_+_26638667 Show fit	0.49	ENST00000600595.1	AC061975.10 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr5_+_162932554 Show fit	0.47	ENST00000321757.6 ENST00000421814.2 ENST00000518095.1	MAT2B Ensembl NCBI GeneCards UniProt Show fit	methionine adenosyltransferase II, beta
chr18_+_29171689 Show fit	0.46	ENST00000237014.3	TTR Ensembl NCBI GeneCards UniProt Show fit	transthyretin
chr15_+_55611128 Show fit	0.45	ENST00000164305.5 ENST00000539642.1	PIGB Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class B

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of BPTF

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.2	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	1.0	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.0	1.0	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.9	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.8	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.7	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.1	0.7	GO:0010133	proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0	0.7	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2	0.6	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.6	GO:0034628	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)

Showing 1 to 10 of 293 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	0.9	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.8	GO:0071564	npBAF complex(GO:0071564)
0.2	0.7	GO:0020003	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0	0.7	GO:0051233	spindle midzone(GO:0051233)
0.2	0.6	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.0	0.6	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.4	GO:0016935	glycine-gated chloride channel complex(GO:0016935)
0.0	0.4	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.4	GO:0005577	fibrinogen complex(GO:0005577)

Showing 1 to 10 of 112 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.2	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	1.0	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.9	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.1	0.8	GO:0016936	galactoside binding(GO:0016936)
0.2	0.7	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.2	0.6	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	0.6	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0	0.6	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.6	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.6	GO:0070008	serine-type exopeptidase activity(GO:0070008)

Showing 1 to 10 of 205 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
1.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
1.3	PID FANCONI PATHWAY	Fanconi anemia pathway
1.0	PID AURORA B PATHWAY	Aurora B signaling
0.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.8	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.7	PID AURORA A PATHWAY	Aurora A signaling
0.7	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.6	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks

Showing 1 to 10 of 17 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	1.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	1.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	1.0	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	1.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.0	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.6	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.6	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints

Showing 1 to 10 of 35 entries

Results for BPTF

Z-value: 1.16

Motif logo

Transcription factors associated with BPTF

Activity-expression correlation:

Activity profile of BPTF motif

Sorted Z-values of BPTF motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of BPTF

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: