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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 1.22

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Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Gene Symbol Gene ID Gene Info
ENSG00000180828.1 basic helix-loop-helix family member e22
ENSG00000180535.3 basic helix-loop-helix family member a15
ENSG00000125533.4 basic helix-loop-helix family member e23

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BHLHA15hg19_v2_chr7_+_97840739_978407860.722.8e-01Click!
BHLHE22hg19_v2_chr8_+_65492756_654928140.406.0e-01Click!

Activity profile of BHLHE22_BHLHA15_BHLHE23 motif

Sorted Z-values of BHLHE22_BHLHA15_BHLHE23 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_32414059 5.64 ENST00000553330.1
Uncharacterized protein
chr16_-_69385681 1.65 ENST00000288025.3
transmembrane emp24 protein transport domain containing 6
chr3_-_121379739 1.48 ENST00000428394.2
ENST00000314583.3
hematopoietic cell-specific Lyn substrate 1
chr1_+_81106951 1.42 ENST00000443565.1
RP5-887A10.1
chr12_-_94673956 1.31 ENST00000551941.1
Uncharacterized protein
chr1_+_186344883 1.31 ENST00000367470.3
chromosome 1 open reading frame 27
chr15_-_98417780 1.23 ENST00000503874.3
long intergenic non-protein coding RNA 923
chr5_-_114632307 1.12 ENST00000506442.1
ENST00000379611.5
coiled-coil domain containing 112
chr1_+_186344945 1.01 ENST00000419367.3
ENST00000287859.6
chromosome 1 open reading frame 27
chr5_-_114631958 0.91 ENST00000395557.4
coiled-coil domain containing 112
chr14_-_107283278 0.87 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr10_+_89124746 0.77 ENST00000465545.1
NUT family member 2D
chr13_+_28813645 0.76 ENST00000282391.5
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_-_182545603 0.73 ENST00000295108.3
neuronal differentiation 1
chr15_-_38519066 0.70 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
chr3_-_129375556 0.68 ENST00000510323.1
transmembrane and coiled-coil domain family 1
chr8_+_67782984 0.66 ENST00000396592.3
ENST00000422365.2
ENST00000492775.1
minichromosome maintenance domain containing 2
chr19_+_42041860 0.62 ENST00000483481.2
ENST00000494375.2
AC006129.4
chr15_-_55700216 0.58 ENST00000569205.1
cell cycle progression 1
chrX_-_84363974 0.52 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
spermidine/spermine N1-acetyl transferase-like 1
chr7_+_116502605 0.51 ENST00000458284.2
ENST00000490693.1
capping protein (actin filament) muscle Z-line, alpha 2
chr1_-_186344802 0.48 ENST00000451586.1
translocated promoter region, nuclear basket protein
chr12_-_91573132 0.46 ENST00000550563.1
ENST00000546370.1
decorin
chr3_-_197300194 0.45 ENST00000358186.2
ENST00000431056.1
3-hydroxybutyrate dehydrogenase, type 1
chr17_+_7211656 0.45 ENST00000416016.2
eukaryotic translation initiation factor 5A
chr15_-_55700522 0.43 ENST00000564092.1
ENST00000310958.6
cell cycle progression 1
chr4_-_74088800 0.43 ENST00000509867.2
ankyrin repeat domain 17
chr11_+_120107344 0.42 ENST00000260264.4
POU class 2 homeobox 3
chr8_+_35649365 0.42 ENST00000437887.1
Uncharacterized protein
chr22_+_20877924 0.40 ENST00000445189.1
mediator complex subunit 15
chr15_-_65503801 0.39 ENST00000261883.4
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr15_-_55700457 0.39 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr15_-_63448973 0.38 ENST00000462430.1
ribosomal protein S27-like
chr3_+_112930306 0.37 ENST00000495514.1
BOC cell adhesion associated, oncogene regulated
chr7_-_101212244 0.36 ENST00000451953.1
ENST00000434537.1
ENST00000437900.1
long intergenic non-protein coding RNA 1007
chr17_+_39846114 0.34 ENST00000586699.1
eukaryotic translation initiation factor 1
chr4_-_159094194 0.33 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr7_-_48068643 0.32 ENST00000453192.2
Sad1 and UNC84 domain containing 3
chr8_-_38239732 0.32 ENST00000534155.1
ENST00000433384.2
ENST00000317025.8
ENST00000316985.3
Wolf-Hirschhorn syndrome candidate 1-like 1
chr3_+_62304648 0.31 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
chromosome 3 open reading frame 14
chr11_-_26743546 0.31 ENST00000280467.6
ENST00000396005.3
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr4_+_55095428 0.31 ENST00000508170.1
ENST00000512143.1
platelet-derived growth factor receptor, alpha polypeptide
chr6_-_108278456 0.30 ENST00000429168.1
SEC63 homolog (S. cerevisiae)
chrX_+_107334895 0.29 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
autophagy related 4A, cysteine peptidase
chr19_+_42041702 0.29 ENST00000487420.2
AC006129.4
chrX_-_15402498 0.29 ENST00000297904.3
c-fos induced growth factor (vascular endothelial growth factor D)
chr9_+_2158485 0.28 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_+_79371565 0.27 ENST00000551304.1
synaptotagmin I
chr5_+_135496675 0.26 ENST00000507637.1
SMAD family member 5
chr7_-_99573677 0.26 ENST00000292401.4
alpha-2-glycoprotein 1, zinc-binding
chr17_-_31404 0.26 ENST00000343572.7
double C2-like domains, beta
chr8_+_21823726 0.26 ENST00000433566.4
exportin 7
chr3_-_114477962 0.25 ENST00000471418.1
zinc finger and BTB domain containing 20
chr3_+_185300270 0.24 ENST00000430355.1
SUMO1/sentrin/SMT3 specific peptidase 2
chr9_+_2158443 0.24 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_-_101724989 0.24 ENST00000517403.1
poly(A) binding protein, cytoplasmic 1
chr5_+_173316341 0.23 ENST00000520867.1
ENST00000334035.5
cytoplasmic polyadenylation element binding protein 4
chr2_-_32490801 0.23 ENST00000360906.5
ENST00000342905.6
NLR family, CARD domain containing 4
chr2_-_228582709 0.22 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
solute carrier family 19 (thiamine transporter), member 3
chr9_+_18474098 0.22 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTS-like 1
chr11_+_66008698 0.22 ENST00000531597.1
phosphofurin acidic cluster sorting protein 1
chr7_+_116502527 0.21 ENST00000361183.3
capping protein (actin filament) muscle Z-line, alpha 2
chr17_+_75316336 0.21 ENST00000591934.1
septin 9
chrX_+_107334983 0.21 ENST00000457035.1
ENST00000545696.1
autophagy related 4A, cysteine peptidase
chr10_-_69597810 0.21 ENST00000483798.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr15_+_65843130 0.21 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr1_+_185126598 0.20 ENST00000450350.1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr1_+_159272111 0.20 ENST00000368114.1
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr3_+_75713481 0.20 ENST00000308062.3
ENST00000464571.1
FSHD region gene 2 family, member C
chrX_+_70798261 0.19 ENST00000373696.3
acidic repeat containing
chr2_+_108994466 0.18 ENST00000272452.2
sulfotransferase family, cytosolic, 1C, member 4
chr1_+_110881945 0.18 ENST00000602849.1
ENST00000487146.2
RNA binding motif protein 15
chr10_-_94257512 0.18 ENST00000371581.5
insulin-degrading enzyme
chr3_+_46924829 0.17 ENST00000313049.5
parathyroid hormone 1 receptor
chr1_-_98515395 0.17 ENST00000424528.2
MIR137 host gene (non-protein coding)
chr2_-_188378368 0.17 ENST00000392365.1
ENST00000435414.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chrX_+_69509870 0.17 ENST00000374388.3
kinesin family member 4A
chr4_+_2814011 0.16 ENST00000502260.1
ENST00000435136.2
SH3-domain binding protein 2
chr20_+_57226841 0.16 ENST00000358029.4
ENST00000361830.3
syntaxin 16
chr10_-_15902449 0.15 ENST00000277632.3
family with sequence similarity 188, member A
chr21_-_36421401 0.15 ENST00000486278.2
runt-related transcription factor 1
chr3_-_114477787 0.15 ENST00000464560.1
zinc finger and BTB domain containing 20
chr8_-_67976509 0.14 ENST00000518747.1
COP9 signalosome subunit 5
chr2_+_105471969 0.14 ENST00000361360.2
POU class 3 homeobox 3
chr17_-_56492989 0.13 ENST00000583753.1
ring finger protein 43
chr4_+_2813946 0.13 ENST00000442312.2
SH3-domain binding protein 2
chr8_+_67976593 0.13 ENST00000262210.5
ENST00000412460.1
centrosome and spindle pole associated protein 1
chr4_+_25915896 0.13 ENST00000514384.1
small integral membrane protein 20
chr20_+_33292507 0.13 ENST00000414082.1
tumor protein p53 inducible nuclear protein 2
chr6_-_119031228 0.12 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
centrosomal protein 85kDa-like
chr4_-_153456153 0.12 ENST00000603548.1
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr8_-_23315190 0.12 ENST00000356206.6
ENST00000358689.4
ENST00000417069.2
ectonucleoside triphosphate diphosphohydrolase 4
chrX_+_69509927 0.12 ENST00000374403.3
kinesin family member 4A
chr19_-_11450249 0.12 ENST00000222120.3
RAB3D, member RAS oncogene family
chr19_+_18208603 0.10 ENST00000262811.6
microtubule associated serine/threonine kinase 3
chr11_-_44972418 0.10 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
tumor protein p53 inducible protein 11
chr9_+_125796806 0.10 ENST00000373642.1
G protein-coupled receptor 21
chr2_+_181845843 0.10 ENST00000602710.1
ubiquitin-conjugating enzyme E2E 3
chr5_-_159766528 0.10 ENST00000505287.2
cyclin J-like
chr16_-_52640834 0.10 ENST00000510238.3
cancer susceptibility candidate 16 (non-protein coding)
chr4_-_113207048 0.09 ENST00000361717.3
TRAF-interacting protein with forkhead-associated domain
chr7_+_107531580 0.09 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
dihydrolipoamide dehydrogenase
chr8_+_62747349 0.09 ENST00000517953.1
ENST00000520097.1
ENST00000519766.1
RP11-705O24.1
chr5_+_157158205 0.09 ENST00000231198.7
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr1_+_47489240 0.09 ENST00000371901.3
cytochrome P450, family 4, subfamily X, polypeptide 1
chr1_-_44818599 0.08 ENST00000537474.1
ERI1 exoribonuclease family member 3
chr12_+_58166370 0.08 ENST00000300209.8
methyltransferase like 21B
chr14_-_51297837 0.08 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
ninein (GSK3B interacting protein)
chr12_+_58166431 0.08 ENST00000333012.5
methyltransferase like 21B
chr11_-_62359027 0.07 ENST00000494385.1
ENST00000308436.7
terminal uridylyl transferase 1, U6 snRNA-specific
chr2_-_227050079 0.07 ENST00000423838.1
AC068138.1
chr12_+_50794592 0.07 ENST00000293618.8
ENST00000429001.3
ENST00000548174.1
ENST00000548697.1
ENST00000548993.1
ENST00000398473.2
ENST00000522085.1
ENST00000518444.1
ENST00000551886.1
La ribonucleoprotein domain family, member 4
chr14_-_69864993 0.06 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr3_-_33700589 0.06 ENST00000461133.3
ENST00000496954.2
cytoplasmic linker associated protein 2
chr7_-_112758665 0.06 ENST00000397764.3
long intergenic non-protein coding RNA 998
chr6_+_4087664 0.05 ENST00000430835.2
chromosome 6 open reading frame 201
chr8_-_23315131 0.05 ENST00000518718.1
ectonucleoside triphosphate diphosphohydrolase 4
chr14_+_24540154 0.05 ENST00000559778.1
ENST00000560761.1
ENST00000557889.1
copine VI (neuronal)
chrX_+_120181457 0.05 ENST00000328078.1
glutamate dehydrogenase 2
chr2_+_234637754 0.04 ENST00000482026.1
ENST00000609767.1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr3_-_33700933 0.04 ENST00000480013.1
cytoplasmic linker associated protein 2
chr3_+_185300391 0.04 ENST00000545472.1
SUMO1/sentrin/SMT3 specific peptidase 2
chr14_-_51297197 0.04 ENST00000382043.4
ninein (GSK3B interacting protein)
chr2_+_99953816 0.04 ENST00000289371.6
eukaryotic translation initiation factor 5B
chr9_+_108424738 0.04 ENST00000334077.3
T-cell acute lymphocytic leukemia 2
chr19_-_52227221 0.04 ENST00000222115.1
ENST00000540069.2
hyaluronan synthase 1
chr2_+_181845763 0.03 ENST00000602499.1
ubiquitin-conjugating enzyme E2E 3
chr12_-_95397442 0.03 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr10_-_74114714 0.03 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DnaJ (Hsp40) homolog, subfamily B, member 12
chr1_+_104293028 0.03 ENST00000370079.3
amylase, alpha 1C (salivary)
chr9_+_12775011 0.03 ENST00000319264.3
leucine rich adaptor protein 1-like
chr15_+_85144217 0.02 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
zinc finger and SCAN domain containing 2
chr17_-_9725388 0.02 ENST00000399363.4
Putative germ cell-specific gene 1-like protein 2
chr1_-_99470368 0.02 ENST00000263177.4
Lipid phosphate phosphatase-related protein type 5
chr8_+_38239882 0.02 ENST00000607047.1
RP11-350N15.5
chr12_+_50794947 0.02 ENST00000552445.1
La ribonucleoprotein domain family, member 4
chr4_+_114214125 0.02 ENST00000509550.1
ankyrin 2, neuronal
chr14_-_51297360 0.01 ENST00000496749.1
ninein (GSK3B interacting protein)
chr3_-_55515202 0.01 ENST00000482079.1
wingless-type MMTV integration site family, member 5A
chr3_-_150264272 0.01 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
stress-associated endoplasmic reticulum protein 1
chr3_+_119298429 0.01 ENST00000478927.1
ADP-ribosylarginine hydrolase
chr17_+_44790515 0.01 ENST00000576346.1
N-ethylmaleimide-sensitive factor
chr2_-_183387430 0.01 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr1_+_61330931 0.01 ENST00000371191.1
nuclear factor I/A
chr11_-_44972476 0.01 ENST00000527685.1
ENST00000308212.5
tumor protein p53 inducible protein 11
chr11_+_32154200 0.01 ENST00000525133.1
RP1-65P5.5
chr10_+_51565108 0.01 ENST00000438493.1
ENST00000452682.1
nuclear receptor coactivator 4
chr10_+_51565188 0.00 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
nuclear receptor coactivator 4
chr1_-_205091115 0.00 ENST00000264515.6
ENST00000367164.1
retinoblastoma binding protein 5
chr16_+_21716284 0.00 ENST00000388957.3
otoancorin
chr3_-_196910721 0.00 ENST00000443183.1
discs, large homolog 1 (Drosophila)
chr4_-_87028478 0.00 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr6_+_31887761 0.00 ENST00000413154.1
complement component 2

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.2 1.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.7 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.2 0.5 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 0.5 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.1 1.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.5 GO:0051697 protein delipidation(GO:0051697)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.8 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.2 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0072240 ascending thin limb development(GO:0072021) distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric ascending thin limb development(GO:0072218) metanephric distal convoluted tubule development(GO:0072221) metanephric DCT cell differentiation(GO:0072240)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0035562 protein desumoylation(GO:0016926) regulation of DNA endoreduplication(GO:0032875) negative regulation of chromatin binding(GO:0035562) DNA endoreduplication(GO:0042023)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0031251 PAN complex(GO:0031251)
0.1 0.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0098576 lumenal side of membrane(GO:0098576)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.1 0.5 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.6 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression