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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for ATF6

Z-value: 1.18

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Transcription factors associated with ATF6

Gene Symbol Gene ID Gene Info
ATF6
ENSG00000118217.5 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF6hg19_v2_chr1_+_161736072_161736093-0.514.9e-01Click!

Activity profile of ATF6 motif

Sorted Z-values of ATF6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_20850171 1.00 ENST00000445987.1
MED15
mediator complex subunit 15
chr21_-_38445297 0.89 ENST00000430792.1
ENST00000399103.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_+_6522922 0.88 ENST00000601673.1
FLJ20306
CDNA FLJ20306 fis, clone HEP06881; Putative uncharacterized protein FLJ20306; Uncharacterized protein
chr9_+_111696664 0.82 ENST00000374624.3
ENST00000445175.1
FAM206A
family with sequence similarity 206, member A
chr12_+_147052 0.79 ENST00000594563.1
AC026369.1
Uncharacterized protein
chr3_+_184530173 0.78 ENST00000453056.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr21_-_38445011 0.72 ENST00000464265.1
ENST00000399102.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr16_+_2570431 0.72 ENST00000563556.1
AMDHD2
amidohydrolase domain containing 2
chr21_-_38445470 0.70 ENST00000399098.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr13_+_36920569 0.66 ENST00000379848.2
SPG20OS
SPG20 opposite strand
chr22_+_38864041 0.62 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr5_+_78532003 0.59 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr8_+_9009296 0.55 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr9_-_100000957 0.54 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
RP11-498P14.5
chrX_+_134478706 0.54 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
ZNF449
zinc finger protein 449
chr14_+_64970427 0.53 ENST00000553583.1
ZBTB1
zinc finger and BTB domain containing 1
chr19_+_35630926 0.51 ENST00000588081.1
ENST00000589121.1
FXYD1
FXYD domain containing ion transport regulator 1
chr3_+_170075436 0.50 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKIL
SKI-like oncogene
chr1_+_193028717 0.46 ENST00000415442.2
ENST00000506303.1
TROVE2
TROVE domain family, member 2
chr6_-_84937314 0.45 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr1_-_151254362 0.43 ENST00000447795.2
RP11-126K1.2
Uncharacterized protein
chr21_-_46237883 0.41 ENST00000397893.3
SUMO3
small ubiquitin-like modifier 3
chr7_-_100808843 0.41 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr1_-_25573977 0.40 ENST00000243189.7
C1orf63
chromosome 1 open reading frame 63
chr3_-_101395936 0.40 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr14_+_65016620 0.40 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr3_+_150264555 0.40 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr17_-_49337392 0.40 ENST00000376381.2
ENST00000586178.1
MBTD1
mbt domain containing 1
chr11_+_20409070 0.39 ENST00000331079.6
PRMT3
protein arginine methyltransferase 3
chr6_-_86353510 0.39 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr3_+_150264458 0.38 ENST00000487799.1
ENST00000460851.1
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr6_-_90062543 0.37 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr1_-_78149041 0.36 ENST00000414381.1
ENST00000370798.1
ZZZ3
zinc finger, ZZ-type containing 3
chr5_+_133984462 0.36 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr8_+_29952914 0.36 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr1_+_9599540 0.35 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr1_-_25573937 0.35 ENST00000417642.2
ENST00000431849.2
C1orf63
chromosome 1 open reading frame 63
chr3_+_3168692 0.35 ENST00000402675.1
ENST00000413000.1
TRNT1
tRNA nucleotidyl transferase, CCA-adding, 1
chr6_+_135818979 0.35 ENST00000421378.2
ENST00000579057.1
ENST00000436554.1
ENST00000438618.2
LINC00271
long intergenic non-protein coding RNA 271
chr17_-_77967433 0.35 ENST00000571872.1
TBC1D16
TBC1 domain family, member 16
chr12_+_54447637 0.33 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr7_-_100808394 0.33 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr19_+_3708338 0.33 ENST00000590545.1
TJP3
tight junction protein 3
chr4_-_169931231 0.33 ENST00000504561.1
CBR4
carbonyl reductase 4
chr6_+_26204825 0.31 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr19_+_35630628 0.31 ENST00000588715.1
ENST00000588607.1
FXYD1
FXYD domain containing ion transport regulator 1
chr4_+_39640787 0.31 ENST00000532680.1
RP11-539G18.2
RP11-539G18.2
chr22_-_38577782 0.31 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr8_-_144099795 0.31 ENST00000522060.1
ENST00000517833.1
ENST00000502167.2
ENST00000518831.1
RP11-273G15.2
RP11-273G15.2
chr11_-_129149197 0.30 ENST00000525234.1
ARHGAP32
Rho GTPase activating protein 32
chr8_-_38126635 0.30 ENST00000529359.1
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
chr5_+_122110691 0.28 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2
sorting nexin 2
chr6_+_135818907 0.27 ENST00000579339.1
ENST00000580741.1
LINC00271
long intergenic non-protein coding RNA 271
chr22_+_24236191 0.27 ENST00000215754.7
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr15_+_96869165 0.26 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr4_-_187647773 0.26 ENST00000509647.1
FAT1
FAT atypical cadherin 1
chr18_-_46987000 0.26 ENST00000442713.2
ENST00000269445.6
DYM
dymeclin
chr16_+_19729586 0.26 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQCK
IQ motif containing K
chr12_+_112451222 0.25 ENST00000552052.1
ERP29
endoplasmic reticulum protein 29
chr7_-_38969150 0.25 ENST00000418457.2
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr8_+_61429728 0.25 ENST00000529579.1
RAB2A
RAB2A, member RAS oncogene family
chr11_-_46638378 0.24 ENST00000529192.1
HARBI1
harbinger transposase derived 1
chr7_-_8301682 0.24 ENST00000396675.3
ENST00000430867.1
ICA1
islet cell autoantigen 1, 69kDa
chr3_+_45067659 0.24 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chr22_-_38577731 0.24 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr2_-_193059634 0.23 ENST00000392314.1
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr6_-_135818844 0.23 ENST00000524469.1
ENST00000367800.4
ENST00000327035.6
ENST00000457866.2
ENST00000265602.6
AHI1
Abelson helper integration site 1
chr2_-_201753859 0.23 ENST00000409361.1
ENST00000392283.4
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr20_+_18118703 0.23 ENST00000464792.1
CSRP2BP
CSRP2 binding protein
chr9_+_100000717 0.23 ENST00000375205.2
ENST00000357054.1
ENST00000395220.1
ENST00000375202.2
ENST00000411667.2
CCDC180
coiled-coil domain containing 180
chr2_+_223726281 0.23 ENST00000413316.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr4_-_54930790 0.22 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr1_-_193028632 0.22 ENST00000421683.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr8_+_94929077 0.22 ENST00000297598.4
ENST00000520614.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr19_-_3600549 0.22 ENST00000589966.1
TBXA2R
thromboxane A2 receptor
chr4_+_108746282 0.22 ENST00000503862.1
SGMS2
sphingomyelin synthase 2
chr10_-_27444143 0.21 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr14_-_35183755 0.21 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr1_+_185126207 0.21 ENST00000367501.3
SWT1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr5_+_94890840 0.21 ENST00000504763.1
ARSK
arylsulfatase family, member K
chr21_+_38445539 0.21 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr7_+_92861653 0.21 ENST00000251739.5
ENST00000305866.5
ENST00000544910.1
ENST00000541136.1
ENST00000458530.1
ENST00000535481.1
ENST00000317751.6
CCDC132
coiled-coil domain containing 132
chrX_+_122993544 0.20 ENST00000422098.1
XIAP
X-linked inhibitor of apoptosis
chr3_+_3168600 0.20 ENST00000251607.6
ENST00000339437.6
ENST00000280591.6
ENST00000420393.1
TRNT1
tRNA nucleotidyl transferase, CCA-adding, 1
chr1_+_185126291 0.20 ENST00000367500.4
SWT1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr2_-_55276320 0.20 ENST00000357376.3
RTN4
reticulon 4
chr2_+_42396472 0.20 ENST00000318522.5
ENST00000402711.2
EML4
echinoderm microtubule associated protein like 4
chr2_-_98612379 0.20 ENST00000425805.2
TMEM131
transmembrane protein 131
chr18_+_12703002 0.20 ENST00000590217.1
PSMG2
proteasome (prosome, macropain) assembly chaperone 2
chr16_+_68298466 0.20 ENST00000568088.1
ENST00000564708.1
SLC7A6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr13_-_49107303 0.19 ENST00000344532.3
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr19_-_44097188 0.19 ENST00000594374.1
L34079.2
L34079.2
chr2_-_98612350 0.19 ENST00000186436.5
TMEM131
transmembrane protein 131
chr6_+_87865262 0.19 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr7_+_116593292 0.19 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
ST7
suppression of tumorigenicity 7
chr2_+_242254507 0.19 ENST00000391973.2
SEPT2
septin 2
chr6_-_135818764 0.19 ENST00000488690.2
AHI1
Abelson helper integration site 1
chr11_+_102217936 0.19 ENST00000532832.1
ENST00000530675.1
ENST00000533742.1
ENST00000227758.2
ENST00000532672.1
ENST00000531259.1
ENST00000527465.1
BIRC2
baculoviral IAP repeat containing 2
chr18_+_56530794 0.19 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532
zinc finger protein 532
chr10_+_64893039 0.19 ENST00000277746.6
ENST00000435510.2
NRBF2
nuclear receptor binding factor 2
chr19_-_52227221 0.19 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr14_+_103388976 0.19 ENST00000299155.5
AMN
amnion associated transmembrane protein
chr4_-_99850243 0.19 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E
eukaryotic translation initiation factor 4E
chr8_-_144623595 0.19 ENST00000262577.5
ZC3H3
zinc finger CCCH-type containing 3
chr7_-_86849836 0.19 ENST00000455575.1
TMEM243
transmembrane protein 243, mitochondrial
chr10_+_93558069 0.18 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr7_+_12726474 0.18 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ARL4A
ADP-ribosylation factor-like 4A
chr19_+_38810447 0.18 ENST00000263372.3
KCNK6
potassium channel, subfamily K, member 6
chrX_-_102941596 0.18 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
MORF4L2
mortality factor 4 like 2
chr2_-_182521699 0.18 ENST00000374969.2
ENST00000339098.5
ENST00000374970.2
CERKL
ceramide kinase-like
chr1_-_20812690 0.18 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_-_27169801 0.18 ENST00000511914.1
HOXA4
homeobox A4
chr12_+_110562135 0.18 ENST00000361948.4
ENST00000552912.1
ENST00000242591.5
ENST00000546374.1
IFT81
intraflagellar transport 81 homolog (Chlamydomonas)
chr2_-_182521823 0.18 ENST00000410087.3
ENST00000409440.3
CERKL
ceramide kinase-like
chr1_+_221051699 0.18 ENST00000366903.6
HLX
H2.0-like homeobox
chr3_-_24536253 0.18 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB
thyroid hormone receptor, beta
chr15_+_23255242 0.18 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr19_-_15442701 0.18 ENST00000594841.1
ENST00000601941.1
BRD4
bromodomain containing 4
chr2_+_242254679 0.18 ENST00000428282.1
ENST00000360051.3
SEPT2
septin 2
chr7_-_37956409 0.18 ENST00000436072.2
SFRP4
secreted frizzled-related protein 4
chr9_-_88356789 0.18 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
AGTPBP1
ATP/GTP binding protein 1
chr20_-_22559211 0.17 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chrX_-_128977364 0.17 ENST00000371064.3
ZDHHC9
zinc finger, DHHC-type containing 9
chr3_-_49933249 0.17 ENST00000434765.1
MST1R
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr1_-_193028426 0.17 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr1_-_94344686 0.17 ENST00000528680.1
DNTTIP2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr8_+_61429416 0.17 ENST00000262646.7
ENST00000531289.1
RAB2A
RAB2A, member RAS oncogene family
chr1_-_226187013 0.17 ENST00000272091.7
SDE2
SDE2 telomere maintenance homolog (S. pombe)
chr1_-_94344754 0.17 ENST00000436063.2
DNTTIP2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr2_+_42396574 0.16 ENST00000401738.3
EML4
echinoderm microtubule associated protein like 4
chr11_+_61717535 0.16 ENST00000534553.1
ENST00000301774.9
BEST1
bestrophin 1
chr1_+_87794150 0.16 ENST00000370544.5
LMO4
LIM domain only 4
chr12_+_50497784 0.16 ENST00000548814.1
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr19_-_18391708 0.16 ENST00000600972.1
JUND
jun D proto-oncogene
chr8_-_41909496 0.16 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A
K(lysine) acetyltransferase 6A
chr15_-_74374891 0.16 ENST00000290438.3
GOLGA6A
golgin A6 family, member A
chr10_+_23728198 0.16 ENST00000376495.3
OTUD1
OTU domain containing 1
chr1_-_113498943 0.15 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr1_-_113498616 0.15 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr7_+_2727817 0.15 ENST00000407112.1
AMZ1
archaelysin family metallopeptidase 1
chr1_-_185126037 0.15 ENST00000367506.5
ENST00000367504.3
TRMT1L
tRNA methyltransferase 1 homolog (S. cerevisiae)-like
chr4_-_1242764 0.15 ENST00000514210.1
ENST00000382952.3
ENST00000290921.6
CTBP1
C-terminal binding protein 1
chr8_+_17104401 0.15 ENST00000324815.3
ENST00000518038.1
VPS37A
vacuolar protein sorting 37 homolog A (S. cerevisiae)
chr1_+_193028552 0.15 ENST00000400968.2
ENST00000432079.1
TROVE2
TROVE domain family, member 2
chr7_+_26240776 0.15 ENST00000337620.4
CBX3
chromobox homolog 3
chr1_-_185286461 0.15 ENST00000367498.3
IVNS1ABP
influenza virus NS1A binding protein
chr3_-_129158850 0.15 ENST00000503197.1
ENST00000249910.1
ENST00000429544.2
ENST00000507208.1
MBD4
methyl-CpG binding domain protein 4
chr3_-_57583052 0.15 ENST00000496292.1
ENST00000489843.1
ARF4
ADP-ribosylation factor 4
chr11_+_18720316 0.15 ENST00000280734.2
TMEM86A
transmembrane protein 86A
chr2_-_40006289 0.15 ENST00000260619.6
ENST00000454352.2
THUMPD2
THUMP domain containing 2
chr2_-_201753980 0.15 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr6_+_127587755 0.14 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146
ring finger protein 146
chr13_+_114238997 0.14 ENST00000538138.1
ENST00000375370.5
TFDP1
transcription factor Dp-1
chr17_-_7197881 0.14 ENST00000007699.5
YBX2
Y box binding protein 2
chr12_+_70636765 0.14 ENST00000552231.1
ENST00000229195.3
ENST00000547780.1
ENST00000418359.3
CNOT2
CCR4-NOT transcription complex, subunit 2
chr5_+_65440032 0.14 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr8_-_38126675 0.14 ENST00000531823.1
ENST00000534339.1
ENST00000524616.1
ENST00000422581.2
ENST00000424479.2
ENST00000419686.2
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
chr11_-_113746212 0.14 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
USP28
ubiquitin specific peptidase 28
chr17_-_44896047 0.14 ENST00000225512.5
WNT3
wingless-type MMTV integration site family, member 3
chr19_+_32836499 0.14 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507
zinc finger protein 507
chr5_+_68389807 0.14 ENST00000380860.4
ENST00000504103.1
ENST00000502979.1
SLC30A5
solute carrier family 30 (zinc transporter), member 5
chr2_-_242255060 0.13 ENST00000413241.1
ENST00000423693.1
ENST00000428482.1
HDLBP
high density lipoprotein binding protein
chr18_+_9913977 0.13 ENST00000400000.2
ENST00000340541.4
VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr6_-_151773232 0.13 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr12_+_72148614 0.13 ENST00000261263.3
RAB21
RAB21, member RAS oncogene family
chr20_-_5107180 0.13 ENST00000379160.3
PCNA
proliferating cell nuclear antigen
chr7_+_5632436 0.13 ENST00000340250.6
ENST00000382361.3
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chrY_+_2803322 0.13 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
ZFY
zinc finger protein, Y-linked
chr13_-_36920872 0.13 ENST00000451493.1
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr9_-_88356733 0.13 ENST00000376083.3
AGTPBP1
ATP/GTP binding protein 1
chr14_-_64970494 0.13 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chr1_+_160313062 0.13 ENST00000294785.5
ENST00000368063.1
ENST00000437169.1
NCSTN
nicastrin
chr2_+_183580954 0.13 ENST00000264065.7
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr8_+_29953163 0.12 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr9_+_112542572 0.12 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr4_+_75310851 0.12 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr13_-_36920420 0.12 ENST00000438666.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr2_+_201754135 0.12 ENST00000409357.1
ENST00000409129.2
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr19_+_10222189 0.12 ENST00000321826.4
P2RY11
purinergic receptor P2Y, G-protein coupled, 11
chr6_+_32936942 0.12 ENST00000496118.2
BRD2
bromodomain containing 2
chr7_+_72848092 0.12 ENST00000344575.3
FZD9
frizzled family receptor 9
chr19_-_6502304 0.12 ENST00000540257.1
ENST00000594276.1
ENST00000594075.1
ENST00000600216.1
ENST00000596926.1
TUBB4A
tubulin, beta 4A class IVa
chr5_+_149737202 0.12 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1
Treacher Collins-Franceschetti syndrome 1
chr20_-_34042558 0.12 ENST00000374372.1
GDF5
growth differentiation factor 5
chr3_+_184529929 0.12 ENST00000287546.4
ENST00000437079.3
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr19_+_57702846 0.12 ENST00000263095.6
ENST00000594126.1
ENST00000600531.1
ENST00000597447.1
ENST00000599653.1
ZNF264
zinc finger protein 264
chr5_-_94890648 0.12 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
TTC37
tetratricopeptide repeat domain 37
chr11_+_118230287 0.12 ENST00000252108.3
ENST00000431736.2
UBE4A
ubiquitination factor E4A
chr3_-_121468513 0.12 ENST00000494517.1
ENST00000393667.3
GOLGB1
golgin B1
chr2_+_219745020 0.12 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr8_+_94929110 0.11 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr6_+_24775641 0.11 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chr17_-_57184260 0.11 ENST00000376149.3
ENST00000393066.3
TRIM37
tripartite motif containing 37
chr12_-_51566849 0.11 ENST00000549867.1
ENST00000307660.4
TFCP2
transcription factor CP2
chr7_-_138720763 0.11 ENST00000275766.1
ZC3HAV1L
zinc finger CCCH-type, antiviral 1-like
chr19_-_6502590 0.11 ENST00000264071.2
TUBB4A
tubulin, beta 4A class IVa
chr6_-_86352982 0.11 ENST00000369622.3
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr19_-_40724246 0.11 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr12_-_76953573 0.11 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
OSBPL8
oxysterol binding protein-like 8
chr5_-_78809950 0.11 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.4 GO:0070121 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.1 0.4 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.6 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 0.3 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.8 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.8 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.8 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 2.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.2 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.1 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.1 0.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.3 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.2 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.5 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.2 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.4 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.4 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.1 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.3 GO:0030647 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0060775 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.5 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.0 GO:1902230 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.7 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0045629 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.1 GO:0036102 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.1 GO:0007135 meiosis II(GO:0007135)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.0 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.0 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.1 GO:0033263 CORVET complex(GO:0033263)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.3 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.3 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.2 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.1 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.3 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity