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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for ALX1_ARX

Z-value: 0.92

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Transcription factors associated with ALX1_ARX

Gene Symbol Gene ID Gene Info
ALX1
ENSG00000180318.3 ALX homeobox 1
ARX
ENSG00000004848.6 aristaless related homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX1hg19_v2_chr12_+_85673868_85673885-0.465.4e-01Click!
ARXhg19_v2_chrX_-_25034065_25034088-0.435.7e-01Click!

Activity profile of ALX1_ARX motif

Sorted Z-values of ALX1_ARX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_95236551 1.66 ENST00000238558.3
GSC
goosecoid homeobox
chr8_+_86999516 0.97 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr5_-_126409159 0.91 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr4_-_176733897 0.90 ENST00000393658.2
GPM6A
glycoprotein M6A
chr6_-_66417107 0.71 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr1_+_92632542 0.69 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chrX_-_19817869 0.63 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr15_+_101417919 0.62 ENST00000561338.1
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr6_-_134639180 0.60 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr2_+_101437487 0.57 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr2_+_12246664 0.56 ENST00000449986.1
AC096559.1
AC096559.1
chr14_+_101293687 0.52 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr10_+_69865866 0.47 ENST00000354393.2
MYPN
myopalladin
chr12_+_1099675 0.47 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr6_-_134639042 0.46 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr12_-_89746264 0.44 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr2_-_145188137 0.43 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr13_+_53602894 0.43 ENST00000219022.2
OLFM4
olfactomedin 4
chr13_-_81801115 0.42 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chr18_+_616711 0.42 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr7_-_93520191 0.41 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr17_-_71228357 0.41 ENST00000583024.1
ENST00000403627.3
ENST00000405159.3
ENST00000581110.1
FAM104A
family with sequence similarity 104, member A
chr7_-_93520259 0.40 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr12_-_91546926 0.40 ENST00000550758.1
DCN
decorin
chr3_-_157824292 0.38 ENST00000483851.2
SHOX2
short stature homeobox 2
chr1_+_206557366 0.34 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chrX_+_36246735 0.34 ENST00000378653.3
CXorf30
chromosome X open reading frame 30
chr1_+_149239529 0.34 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr11_-_58035732 0.34 ENST00000395079.2
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chr18_+_616672 0.33 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr15_+_44719996 0.33 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_+_12976450 0.31 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr8_-_40200903 0.31 ENST00000522486.1
CTA-392C11.1
CTA-392C11.1
chr8_-_112248400 0.30 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4
chrX_+_35937843 0.30 ENST00000297866.5
CXorf22
chromosome X open reading frame 22
chr6_-_154751629 0.30 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr1_-_94147385 0.29 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chrX_+_36254051 0.29 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chrX_-_55208866 0.28 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr3_-_164914640 0.27 ENST00000241274.3
SLITRK3
SLIT and NTRK-like family, member 3
chr3_-_27763803 0.27 ENST00000449599.1
EOMES
eomesodermin
chr1_+_104615595 0.27 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chr16_-_21875424 0.27 ENST00000541674.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr12_+_14369524 0.27 ENST00000538329.1
RP11-134N1.2
RP11-134N1.2
chrX_+_107288239 0.27 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chrX_-_15332665 0.26 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr2_+_162272605 0.26 ENST00000389554.3
TBR1
T-box, brain, 1
chr1_+_158978768 0.25 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr1_-_154600421 0.25 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chrM_+_7586 0.25 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr6_+_31895254 0.24 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr5_+_36152091 0.24 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr11_-_111649074 0.23 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr10_+_97709725 0.23 ENST00000472454.2
RP11-248J23.6
Protein LOC100652732
chr5_-_152069089 0.23 ENST00000506723.2
AC091969.1
AC091969.1
chr14_-_101036119 0.23 ENST00000355173.2
BEGAIN
brain-enriched guanylate kinase-associated
chr10_+_24544249 0.23 ENST00000430453.2
KIAA1217
KIAA1217
chr6_-_26199499 0.22 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr1_+_15668240 0.22 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr1_-_178840157 0.22 ENST00000367629.1
ENST00000234816.2
ANGPTL1
angiopoietin-like 1
chr11_-_95522639 0.22 ENST00000536839.1
FAM76B
family with sequence similarity 76, member B
chr12_-_112123524 0.22 ENST00000327551.6
BRAP
BRCA1 associated protein
chr8_-_40200877 0.21 ENST00000521030.1
CTA-392C11.1
CTA-392C11.1
chr15_+_44719790 0.21 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr9_-_71869642 0.19 ENST00000600472.1
AL358113.1
Tight junction protein 2 (Zona occludens 2) isoform 1 variant; Uncharacterized protein
chrX_+_107288197 0.19 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr7_-_91794590 0.19 ENST00000430130.2
ENST00000454089.2
LRRD1
leucine-rich repeats and death domain containing 1
chr5_-_39270725 0.19 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr13_-_47471155 0.19 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr5_+_59783540 0.19 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr10_-_21186144 0.19 ENST00000377119.1
NEBL
nebulette
chr3_-_196242233 0.19 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr17_-_39023462 0.19 ENST00000251643.4
KRT12
keratin 12
chr7_+_90338712 0.19 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr11_-_16419067 0.19 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr2_+_179184955 0.18 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr17_+_75181292 0.18 ENST00000431431.2
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr5_-_55412774 0.18 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr9_+_88556444 0.18 ENST00000376040.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr2_-_145278475 0.18 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr10_-_99030395 0.18 ENST00000355366.5
ENST00000371027.1
ARHGAP19
Rho GTPase activating protein 19
chr7_-_7575477 0.18 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr4_-_119759795 0.17 ENST00000419654.2
SEC24D
SEC24 family member D
chr1_+_44679113 0.17 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
DMAP1
DNA methyltransferase 1 associated protein 1
chr2_+_58655461 0.17 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr5_-_136649218 0.17 ENST00000510405.1
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chrX_-_15619076 0.17 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr16_+_22518495 0.17 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr11_-_95523500 0.16 ENST00000540054.1
FAM76B
family with sequence similarity 76, member B
chr12_+_104337515 0.16 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr3_-_124774802 0.15 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr4_-_69083720 0.14 ENST00000432593.3
TMPRSS11BNL
TMPRSS11B N-terminal like
chr10_+_134150835 0.14 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr8_-_122653630 0.14 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr6_+_27791862 0.14 ENST00000355057.1
HIST1H4J
histone cluster 1, H4j
chr6_+_45296391 0.14 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr3_-_12587055 0.14 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr16_+_1728257 0.14 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
HN1L
hematological and neurological expressed 1-like
chr4_+_169013666 0.14 ENST00000359299.3
ANXA10
annexin A10
chr18_-_52989525 0.14 ENST00000457482.3
TCF4
transcription factor 4
chr15_+_48483736 0.14 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr1_-_110933611 0.14 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr16_+_68119440 0.14 ENST00000346183.3
ENST00000329524.4
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr6_-_133055815 0.14 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr12_-_21928515 0.13 ENST00000537950.1
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr3_+_138340049 0.13 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr6_+_31895287 0.13 ENST00000447952.2
C2
complement component 2
chr6_+_88106840 0.12 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chr5_+_145826867 0.12 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr8_-_57123815 0.12 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr19_-_54619006 0.12 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr5_-_115872142 0.12 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_-_10324716 0.12 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr1_+_186265399 0.12 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr15_+_44092784 0.12 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr16_+_24549014 0.12 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr5_+_142149932 0.12 ENST00000274498.4
ARHGAP26
Rho GTPase activating protein 26
chr11_-_111649015 0.11 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr4_+_74347400 0.11 ENST00000226355.3
AFM
afamin
chr16_+_68119247 0.11 ENST00000575270.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr14_+_24099318 0.11 ENST00000432832.2
DHRS2
dehydrogenase/reductase (SDR family) member 2
chr1_+_44679159 0.11 ENST00000315913.5
ENST00000372289.2
DMAP1
DNA methyltransferase 1 associated protein 1
chr11_-_95522907 0.11 ENST00000358780.5
ENST00000542135.1
FAM76B
family with sequence similarity 76, member B
chr3_-_98241760 0.11 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1
claudin domain containing 1
chr3_+_159943362 0.11 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr12_-_125052010 0.11 ENST00000458234.1
NCOR2
nuclear receptor corepressor 2
chr1_+_52682052 0.11 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr5_+_140227357 0.10 ENST00000378122.3
PCDHA9
protocadherin alpha 9
chr2_+_29001711 0.10 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr5_+_101569696 0.10 ENST00000597120.1
AC008948.1
AC008948.1
chr8_-_10512569 0.10 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr3_+_138340067 0.10 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr14_+_38264418 0.10 ENST00000267368.7
ENST00000382320.3
TTC6
tetratricopeptide repeat domain 6
chr22_-_30642728 0.10 ENST00000403987.3
LIF
leukemia inhibitory factor
chr12_+_59989918 0.10 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr8_+_11961898 0.10 ENST00000400085.3
ZNF705D
zinc finger protein 705D
chr8_-_6420930 0.10 ENST00000325203.5
ANGPT2
angiopoietin 2
chr4_+_95376396 0.10 ENST00000508216.1
ENST00000514743.1
PDLIM5
PDZ and LIM domain 5
chr6_-_41039567 0.10 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr5_+_36152179 0.09 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr15_+_42066632 0.09 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr1_-_13390765 0.09 ENST00000357367.2
PRAMEF8
PRAME family member 8
chr2_+_84542187 0.09 ENST00000440495.1
AC106874.1
AC106874.1
chr8_+_77318769 0.09 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr12_-_89746173 0.09 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr17_-_60885645 0.09 ENST00000544856.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr17_+_44588877 0.09 ENST00000576629.1
LRRC37A2
leucine rich repeat containing 37, member A2
chr3_+_111753690 0.09 ENST00000452346.2
TMPRSS7
transmembrane protease, serine 7
chr15_+_44719970 0.09 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr6_+_15401075 0.09 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr17_-_60885659 0.09 ENST00000311269.5
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr7_+_18548878 0.09 ENST00000456174.2
HDAC9
histone deacetylase 9
chr5_-_59783882 0.08 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_+_140227048 0.08 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr10_+_97803151 0.08 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ
cyclin J
chr15_+_66874502 0.08 ENST00000558797.1
RP11-321F6.1
HCG2003567; Uncharacterized protein
chr17_-_60885700 0.08 ENST00000583600.1
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr9_-_23779367 0.08 ENST00000440102.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr4_-_174320687 0.08 ENST00000296506.3
SCRG1
stimulator of chondrogenesis 1
chr1_-_21377383 0.08 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr3_+_140981456 0.08 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr17_-_5321549 0.08 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr8_+_67039131 0.08 ENST00000315962.4
ENST00000353317.5
TRIM55
tripartite motif containing 55
chr7_+_90339169 0.08 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr19_-_38183228 0.07 ENST00000587199.1
ZFP30
ZFP30 zinc finger protein
chr7_-_82792215 0.07 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chr2_+_228678550 0.07 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr14_+_57671888 0.07 ENST00000391612.1
AL391152.1
AL391152.1
chr6_-_137314371 0.07 ENST00000432330.1
ENST00000418699.1
RP11-55K22.5
RP11-55K22.5
chr7_+_93535817 0.07 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr5_+_38148582 0.07 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr12_+_12878829 0.07 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr3_-_87325728 0.07 ENST00000350375.2
POU1F1
POU class 1 homeobox 1
chr14_-_81425828 0.07 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr4_+_156824840 0.06 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr5_+_59783941 0.06 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr5_+_142149955 0.06 ENST00000378004.3
ARHGAP26
Rho GTPase activating protein 26
chr6_-_133055896 0.06 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr10_-_29923893 0.06 ENST00000355867.4
SVIL
supervillin
chr1_-_110155671 0.06 ENST00000351050.3
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr12_+_54410664 0.06 ENST00000303406.4
HOXC4
homeobox C4
chr12_-_57873329 0.05 ENST00000424809.2
ARHGAP9
Rho GTPase activating protein 9
chr7_+_18548924 0.05 ENST00000524023.1
HDAC9
histone deacetylase 9
chr4_+_118955500 0.05 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_+_183774285 0.05 ENST00000539189.1
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr5_+_133562095 0.05 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chrX_+_30248553 0.05 ENST00000361644.2
MAGEB3
melanoma antigen family B, 3
chr4_-_89951028 0.05 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr5_+_140514782 0.05 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr6_-_27835357 0.05 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr13_+_74805561 0.05 ENST00000419499.1
LINC00402
long intergenic non-protein coding RNA 402
chrX_-_138724994 0.05 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr2_+_119699864 0.05 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr1_+_84630574 0.05 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_137203557 0.05 ENST00000515645.1
MYOT
myotilin
chr15_+_51669444 0.05 ENST00000396399.2
GLDN
gliomedin
chr22_-_43398442 0.05 ENST00000422336.1
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr2_-_145275228 0.04 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr7_+_107224364 0.04 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr16_+_68119324 0.04 ENST00000349223.5
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX1_ARX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.5 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 1.7 GO:0014029 neural crest formation(GO:0014029)
0.1 1.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.7 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.2 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:0021764 amygdala development(GO:0021764)
0.0 0.4 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.2 GO:0002035 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.8 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.0 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.6 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0045362 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.8 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005549 odorant binding(GO:0005549)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 1.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 2.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation