ISMARA results: AGUGCAA

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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for AGUGCAA

Z-value: 1.06

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miRNA associated with seed AGUGCAA

Name	miRBASE accession
hsa-miR-130a-3p miRBase	MIMAT0000425
hsa-miR-130b-3p miRBase	MIMAT0000691
hsa-miR-301a-3p miRBase	MIMAT0000688
hsa-miR-301b-3p miRBase	MIMAT0004958
hsa-miR-454-3p miRBase	MIMAT0003885
hsa-miR-3666 miRBase	MIMAT0018088
hsa-miR-4295 miRBase	MIMAT0016844

Activity profile of AGUGCAA motif

Sorted Z-values of AGUGCAA motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_-_76598296 Show fit	0.89	ENST00000395719.3	G3BP2 Ensembl NCBI GeneCards UniProt Show fit	GTPase activating protein (SH3 domain) binding protein 2
chr3_-_178790057 Show fit	0.70	ENST00000311417.2	ZMAT3 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, matrin-type 3
chr12_+_56473628 Show fit	0.63	ENST00000549282.1 ENST00000549061.1 ENST00000267101.3	ERBB3 Ensembl NCBI GeneCards UniProt Show fit	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr4_+_15004165 Show fit	0.61	ENST00000538197.1 ENST00000541112.1 ENST00000442003.2	CPEB2 Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic polyadenylation element binding protein 2
chr1_+_47799446 Show fit	0.61	ENST00000371873.5	CMPK1 Ensembl NCBI GeneCards UniProt Show fit	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr1_-_51984908 Show fit	0.60	ENST00000371730.2	EPS15 Ensembl NCBI GeneCards UniProt Show fit	epidermal growth factor receptor pathway substrate 15
chr18_+_9136758 Show fit	0.59	ENST00000383440.2 ENST00000262126.4 ENST00000577992.1	ANKRD12 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 12
chr15_-_34502278 Show fit	0.55	ENST00000559515.1 ENST00000256544.3 ENST00000560108.1 ENST00000559462.1	KATNBL1 Ensembl NCBI GeneCards UniProt Show fit	katanin p80 subunit B-like 1
chr2_+_103236004 Show fit	0.55	ENST00000233969.2	SLC9A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr18_+_72922710 Show fit	0.54	ENST00000322038.5	TSHZ1 Ensembl NCBI GeneCards UniProt Show fit	teashirt zinc finger homeobox 1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGCAA

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.9	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.7	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2	0.6	GO:0003274	endocardial cushion fusion(GO:0003274)
0.1	0.6	GO:0061763	multivesicular body-lysosome fusion(GO:0061763)
0.1	0.6	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.1	0.6	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	0.6	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.6	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.2	0.5	GO:0097195	pilomotor reflex(GO:0097195)
0.1	0.5	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)

Showing 1 to 10 of 118 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.8	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.1	0.7	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.6	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.2	0.5	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	0.5	GO:0034678	smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.1	0.5	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.5	GO:0090543	Flemming body(GO:0090543)
0.0	0.5	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.5	GO:0000407	pre-autophagosomal structure(GO:0000407)

Showing 1 to 10 of 47 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.7	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	0.6	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.6	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.6	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.6	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.6	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.2	0.5	GO:0071633	dihydroceramidase activity(GO:0071633)
0.0	0.5	GO:0015386	potassium:proton antiporter activity(GO:0015386)

Showing 1 to 10 of 69 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
2.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
1.3	SIG CHEMOTAXIS	Genes related to chemotaxis
1.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.6	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.5	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.5	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.3	PID S1P S1P2 PATHWAY	S1P2 pathway

Showing 1 to 10 of 11 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Total log-likelihood	Term	Description
0.8	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.8	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.5	REACTOME KINESINS	Genes involved in Kinesins
0.4	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome

Showing 1 to 10 of 19 entries

Results for AGUGCAA

Z-value: 1.06

Motif logo

miRNA associated with seed AGUGCAA

Activity profile of AGUGCAA motif

Sorted Z-values of AGUGCAA motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGCAA

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: