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avrg: A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 0.08

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Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Gene Symbol Gene ID Gene Info
ENSG00000180828.1 BHLHE22
ENSG00000180535.3 BHLHA15
ENSG00000125533.4 BHLHE23

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BHLHE22hg19_v2_chr8_+_65492756_65492814-0.019.9e-01Click!
BHLHA15hg19_v2_chr7_+_97840739_978407860.001.0e+00Click!

Activity profile of BHLHE22_BHLHA15_BHLHE23 motif

Sorted Z-values of BHLHE22_BHLHA15_BHLHE23 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_142264664 0.52 ENST00000518520.1
RP11-10J21.3
Uncharacterized protein
chr1_+_95975672 0.38 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr6_+_135502501 0.18 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr1_-_168464875 0.17 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr15_-_98417780 0.16 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr8_+_38239882 0.16 ENST00000607047.1
RP11-350N15.5
RP11-350N15.5
chr7_-_27205136 0.16 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr8_-_101724989 0.13 ENST00000517403.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr10_-_31288398 0.11 ENST00000538351.2
ZNF438
zinc finger protein 438
chr3_-_121379739 0.10 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr15_-_55700216 0.09 ENST00000569205.1
CCPG1
cell cycle progression 1
chr5_-_111312622 0.09 ENST00000395634.3
NREP
neuronal regeneration related protein
chr5_-_114632307 0.08 ENST00000506442.1
ENST00000379611.5
CCDC112
coiled-coil domain containing 112
chr12_-_75723805 0.08 ENST00000409799.1
ENST00000409445.3
CAPS2
calcyphosine 2
chr4_-_74088800 0.08 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr5_+_135496675 0.08 ENST00000507637.1
SMAD5
SMAD family member 5
chr8_-_38239732 0.08 ENST00000534155.1
ENST00000433384.2
ENST00000317025.8
ENST00000316985.3
WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr12_+_79371565 0.08 ENST00000551304.1
SYT1
synaptotagmin I
chrX_+_70798261 0.08 ENST00000373696.3
ACRC
acidic repeat containing
chr1_+_100810575 0.08 ENST00000542213.1
CDC14A
cell division cycle 14A
chr5_-_137674000 0.07 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr5_-_114631958 0.07 ENST00000395557.4
CCDC112
coiled-coil domain containing 112
chr7_+_114562909 0.07 ENST00000423503.1
ENST00000427207.1
MDFIC
MyoD family inhibitor domain containing
chr19_-_37019562 0.07 ENST00000523638.1
ZNF260
zinc finger protein 260
chr12_-_94673956 0.06 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr15_-_55700522 0.06 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr7_-_38403077 0.06 ENST00000426402.2
TRGV2
T cell receptor gamma variable 2
chr6_+_97010424 0.06 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
FHL5
four and a half LIM domains 5
chr1_+_186344883 0.06 ENST00000367470.3
C1orf27
chromosome 1 open reading frame 27
chr3_-_131753830 0.06 ENST00000429747.1
CPNE4
copine IV
chr4_+_25915896 0.05 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr20_+_33292507 0.05 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr3_-_196910477 0.05 ENST00000447466.1
DLG1
discs, large homolog 1 (Drosophila)
chr7_-_101212244 0.04 ENST00000451953.1
ENST00000434537.1
ENST00000437900.1
LINC01007
long intergenic non-protein coding RNA 1007
chr5_+_157158205 0.04 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr12_+_50794947 0.04 ENST00000552445.1
LARP4
La ribonucleoprotein domain family, member 4
chr15_-_38519066 0.04 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr3_-_196910721 0.04 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr3_-_196911002 0.04 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr3_+_185300391 0.04 ENST00000545472.1
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr17_-_37764128 0.04 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr12_-_91573132 0.04 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr2_-_182545603 0.04 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr14_-_51297837 0.04 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
NIN
ninein (GSK3B interacting protein)
chr2_-_188378368 0.04 ENST00000392365.1
ENST00000435414.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr1_+_185126598 0.03 ENST00000450350.1
SWT1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr13_+_49551020 0.03 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr3_+_171758344 0.03 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr8_+_67976593 0.03 ENST00000262210.5
ENST00000412460.1
CSPP1
centrosome and spindle pole associated protein 1
chr1_+_159272111 0.03 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr1_+_186344945 0.03 ENST00000419367.3
ENST00000287859.6
C1orf27
chromosome 1 open reading frame 27
chr6_-_108278456 0.03 ENST00000429168.1
SEC63
SEC63 homolog (S. cerevisiae)
chr4_-_41216619 0.03 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chrX_-_13835461 0.03 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr11_-_8795787 0.03 ENST00000528196.1
ENST00000533681.1
ST5
suppression of tumorigenicity 5
chrX_+_69509870 0.03 ENST00000374388.3
KIF4A
kinesin family member 4A
chr3_+_119298429 0.03 ENST00000478927.1
ADPRH
ADP-ribosylarginine hydrolase
chr5_-_159766528 0.03 ENST00000505287.2
CCNJL
cyclin J-like
chrX_-_19817869 0.03 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr11_-_6008215 0.03 ENST00000332249.4
OR52L1
olfactory receptor, family 52, subfamily L, member 1
chrX_+_107334895 0.03 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr17_-_9725388 0.03 ENST00000399363.4
RP11-477N12.3
Putative germ cell-specific gene 1-like protein 2
chr12_-_95397442 0.03 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr12_-_108714412 0.03 ENST00000412676.1
ENST00000550573.1
CMKLR1
chemokine-like receptor 1
chr11_+_120107344 0.03 ENST00000260264.4
POU2F3
POU class 2 homeobox 3
chr2_-_32490801 0.03 ENST00000360906.5
ENST00000342905.6
NLRC4
NLR family, CARD domain containing 4
chr19_+_57874835 0.03 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
TRAPPC2P1
ZNF547
AC003002.4
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr17_-_31404 0.03 ENST00000343572.7
DOC2B
double C2-like domains, beta
chr4_-_129491686 0.03 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr12_+_41136144 0.02 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr8_-_23315190 0.02 ENST00000356206.6
ENST00000358689.4
ENST00000417069.2
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr15_-_55700457 0.02 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1
cell cycle progression 1
chr11_+_94501497 0.02 ENST00000317829.8
ENST00000317837.9
ENST00000433060.2
AMOTL1
angiomotin like 1
chr6_-_112115074 0.02 ENST00000368667.2
FYN
FYN oncogene related to SRC, FGR, YES
chr10_-_15902449 0.02 ENST00000277632.3
FAM188A
family with sequence similarity 188, member A
chr12_+_50794730 0.02 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
LARP4
La ribonucleoprotein domain family, member 4
chr4_-_153456153 0.02 ENST00000603548.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr14_-_107283278 0.02 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr14_-_51297197 0.02 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr1_+_61330931 0.02 ENST00000371191.1
NFIA
nuclear factor I/A
chr3_+_62304648 0.02 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr2_-_165424973 0.02 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr2_+_99953816 0.02 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr20_+_57226841 0.02 ENST00000358029.4
ENST00000361830.3
STX16
syntaxin 16
chr5_-_171433579 0.02 ENST00000265094.5
ENST00000393802.2
FBXW11
F-box and WD repeat domain containing 11
chr4_+_160188889 0.02 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr8_-_23315131 0.02 ENST00000518718.1
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr12_+_50794592 0.02 ENST00000293618.8
ENST00000429001.3
ENST00000548174.1
ENST00000548697.1
ENST00000548993.1
ENST00000398473.2
ENST00000522085.1
ENST00000518444.1
ENST00000551886.1
LARP4
La ribonucleoprotein domain family, member 4
chrX_-_129402857 0.02 ENST00000447817.1
ENST00000370978.4
ZNF280C
zinc finger protein 280C
chr12_+_50794891 0.02 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chrX_+_128913906 0.02 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr11_+_66008698 0.02 ENST00000531597.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr19_-_52227221 0.01 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chrX_+_69509927 0.01 ENST00000374403.3
KIF4A
kinesin family member 4A
chr1_+_47489240 0.01 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr13_+_111766897 0.01 ENST00000317133.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr17_+_44790515 0.01 ENST00000576346.1
NSF
N-ethylmaleimide-sensitive factor
chr4_+_74301880 0.01 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chrX_+_107334983 0.01 ENST00000457035.1
ENST00000545696.1
ATG4A
autophagy related 4A, cysteine peptidase
chr15_+_63354769 0.01 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr7_+_116502605 0.01 ENST00000458284.2
ENST00000490693.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr14_-_69864993 0.01 ENST00000555373.1
ERH
enhancer of rudimentary homolog (Drosophila)
chr1_+_110881945 0.01 ENST00000602849.1
ENST00000487146.2
RBM15
RNA binding motif protein 15
chr2_+_210444298 0.01 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr1_-_98515395 0.01 ENST00000424528.2
MIR137HG
MIR137 host gene (non-protein coding)
chr21_-_36421401 0.01 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr2_+_186603355 0.01 ENST00000343098.5
FSIP2
fibrous sheath interacting protein 2
chr4_+_55095428 0.01 ENST00000508170.1
ENST00000512143.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr12_-_30887948 0.01 ENST00000433722.2
CAPRIN2
caprin family member 2
chr10_+_51565188 0.01 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr3_-_33700933 0.01 ENST00000480013.1
CLASP2
cytoplasmic linker associated protein 2
chr6_+_155443048 0.01 ENST00000535583.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chr9_+_2158443 0.01 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_-_37009882 0.01 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
RPL23
ribosomal protein L23
chr8_+_21823726 0.01 ENST00000433566.4
XPO7
exportin 7
chr7_+_107531580 0.01 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
DLD
dihydrolipoamide dehydrogenase
chr6_+_30539153 0.01 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ABCF1
ATP-binding cassette, sub-family F (GCN20), member 1
chr17_-_47286729 0.01 ENST00000300406.2
ENST00000511277.1
ENST00000511673.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr5_-_171433819 0.01 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr14_-_69444957 0.01 ENST00000556571.1
ENST00000553659.1
ENST00000555616.1
ACTN1
actinin, alpha 1
chr22_-_30953587 0.01 ENST00000453479.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr2_-_32490859 0.01 ENST00000404025.2
NLRC4
NLR family, CARD domain containing 4
chr2_+_210444748 0.01 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr4_+_55095264 0.01 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr16_+_14726672 0.00 ENST00000261658.2
ENST00000563971.1
BFAR
bifunctional apoptosis regulator
chr10_+_51565108 0.00 ENST00000438493.1
ENST00000452682.1
NCOA4
nuclear receptor coactivator 4
chr8_+_67782984 0.00 ENST00000396592.3
ENST00000422365.2
ENST00000492775.1
MCMDC2
minichromosome maintenance domain containing 2
chr10_+_133918175 0.00 ENST00000298622.4
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr7_-_55930443 0.00 ENST00000388975.3
SEPT14
septin 14
chr16_+_72142195 0.00 ENST00000563819.1
ENST00000567142.2
DHX38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr3_+_46924829 0.00 ENST00000313049.5
PTH1R
parathyroid hormone 1 receptor
chr16_-_4896205 0.00 ENST00000589389.1
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr2_+_181845763 0.00 ENST00000602499.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr11_-_88796803 0.00 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr17_-_39597173 0.00 ENST00000246646.3
KRT38
keratin 38
chr1_+_240255166 0.00 ENST00000319653.9
FMN2
formin 2
chr8_-_67976509 0.00 ENST00000518747.1
COPS5
COP9 signalosome subunit 5
chrX_-_13835147 0.00 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr9_+_2158485 0.00 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_114214125 0.00 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr11_+_32154200 0.00 ENST00000525133.1
RP1-65P5.5
RP1-65P5.5
chr2_-_163100045 0.00 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr14_+_24540046 0.00 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6
copine VI (neuronal)
chr2_-_163099885 0.00 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr2_+_219840955 0.00 ENST00000598002.1
ENST00000432733.1
LINC00608
long intergenic non-protein coding RNA 608

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.0 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.0 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)