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avrg: A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for E2F2_E2F5

Z-value: 2.15

Motif logo

Transcription factors associated with E2F2_E2F5

Gene Symbol Gene ID Gene Info
ENSG00000007968.6 E2F2
ENSG00000133740.6 E2F5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F5hg19_v2_chr8_+_86099884_860999200.973.5e-02Click!
E2F2hg19_v2_chr1_-_23857698_23857733-0.732.7e-01Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_27833034 1.32 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr6_+_27782788 0.76 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr6_+_24775641 0.73 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chr1_-_91487013 0.64 ENST00000347275.5
ENST00000370440.1
ZNF644
zinc finger protein 644
chr11_-_19263145 0.63 ENST00000532666.1
ENST00000527884.1
E2F8
E2F transcription factor 8
chr11_-_95522907 0.59 ENST00000358780.5
ENST00000542135.1
FAM76B
family with sequence similarity 76, member B
chr15_-_71184724 0.56 ENST00000560604.1
THAP10
THAP domain containing 10
chr14_+_36295638 0.56 ENST00000543183.1
BRMS1L
breast cancer metastasis-suppressor 1-like
chr11_-_95522639 0.52 ENST00000536839.1
FAM76B
family with sequence similarity 76, member B
chr18_+_19192228 0.48 ENST00000300413.5
ENST00000579618.1
ENST00000582475.1
SNRPD1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr1_+_228645796 0.48 ENST00000369160.2
HIST3H2BB
histone cluster 3, H2bb
chrX_-_152736013 0.48 ENST00000330912.2
ENST00000338525.2
ENST00000334497.2
ENST00000370232.1
ENST00000370212.3
ENST00000370211.4
TREX2
HAUS7
three prime repair exonuclease 2
HAUS augmin-like complex, subunit 7
chr11_-_57102947 0.44 ENST00000526696.1
SSRP1
structure specific recognition protein 1
chr1_-_26232522 0.44 ENST00000399728.1
STMN1
stathmin 1
chr10_+_62538248 0.41 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr22_+_20105259 0.41 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1
RAN binding protein 1
chr19_+_58694742 0.41 ENST00000597528.1
ENST00000594839.1
ZNF274
zinc finger protein 274
chr7_+_26241325 0.39 ENST00000456948.1
ENST00000409747.1
CBX3
chromobox homolog 3
chr5_-_79950371 0.38 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
DHFR
dihydrofolate reductase
chr19_+_8455200 0.38 ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr3_+_10857885 0.38 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr22_+_20105012 0.38 ENST00000331821.3
ENST00000411892.1
RANBP1
RAN binding protein 1
chr12_-_12849073 0.38 ENST00000332427.2
ENST00000540796.1
GPR19
G protein-coupled receptor 19
chrX_-_45710920 0.37 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr19_-_10305302 0.37 ENST00000592054.1
DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr2_-_55277692 0.37 ENST00000394611.2
RTN4
reticulon 4
chr5_-_36152031 0.37 ENST00000296603.4
LMBRD2
LMBR1 domain containing 2
chr10_+_103912137 0.37 ENST00000603742.1
ENST00000488254.2
ENST00000461421.1
ENST00000476468.1
ENST00000370007.5
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr2_-_203103281 0.36 ENST00000392244.3
ENST00000409181.1
ENST00000409712.1
ENST00000409498.2
ENST00000409368.1
ENST00000392245.1
ENST00000392246.2
SUMO1
small ubiquitin-like modifier 1
chr6_-_132272504 0.36 ENST00000367976.3
CTGF
connective tissue growth factor
chr1_-_36235529 0.35 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
CLSPN
claspin
chr1_+_212782012 0.35 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr7_+_26241310 0.34 ENST00000396386.2
CBX3
chromobox homolog 3
chr17_-_77179487 0.34 ENST00000580508.1
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr19_+_58694396 0.34 ENST00000326804.4
ENST00000345813.3
ENST00000424679.2
ZNF274
zinc finger protein 274
chr1_-_91487770 0.33 ENST00000337393.5
ZNF644
zinc finger protein 644
chr16_-_2827128 0.33 ENST00000494946.2
ENST00000409477.1
ENST00000572954.1
ENST00000262306.7
ENST00000409906.4
TCEB2
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
chr2_-_136633940 0.33 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr17_-_17184605 0.31 ENST00000268717.5
COPS3
COP9 signalosome subunit 3
chr17_+_29158962 0.31 ENST00000321990.4
ATAD5
ATPase family, AAA domain containing 5
chr8_-_94928861 0.31 ENST00000607097.1
MIR378D2
microRNA 378d-2
chr22_+_20104947 0.30 ENST00000402752.1
RANBP1
RAN binding protein 1
chr2_-_55277436 0.30 ENST00000354474.6
RTN4
reticulon 4
chr20_+_5931275 0.29 ENST00000378896.3
ENST00000378883.1
MCM8
minichromosome maintenance complex component 8
chr6_-_27114577 0.29 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr1_-_212208842 0.29 ENST00000366992.3
ENST00000366993.3
ENST00000440600.2
ENST00000366994.3
INTS7
integrator complex subunit 7
chr2_+_17935119 0.28 ENST00000317402.7
GEN1
GEN1 Holliday junction 5' flap endonuclease
chr2_+_48010312 0.28 ENST00000540021.1
MSH6
mutS homolog 6
chr1_-_91487806 0.28 ENST00000361321.5
ZNF644
zinc finger protein 644
chrX_-_135849484 0.27 ENST00000370620.1
ENST00000535227.1
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr13_+_114238997 0.27 ENST00000538138.1
ENST00000375370.5
TFDP1
transcription factor Dp-1
chr8_-_124408652 0.27 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr6_+_27775899 0.26 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr11_-_95523500 0.26 ENST00000540054.1
FAM76B
family with sequence similarity 76, member B
chr11_-_19262486 0.25 ENST00000250024.4
E2F8
E2F transcription factor 8
chr6_+_31633011 0.25 ENST00000375885.4
CSNK2B
casein kinase 2, beta polypeptide
chr12_-_125398850 0.25 ENST00000535859.1
ENST00000546271.1
ENST00000540700.1
ENST00000546120.1
UBC
ubiquitin C
chr10_+_112327425 0.25 ENST00000361804.4
SMC3
structural maintenance of chromosomes 3
chr1_-_36235559 0.25 ENST00000251195.5
CLSPN
claspin
chr17_+_42733803 0.25 ENST00000409122.2
C17orf104
chromosome 17 open reading frame 104
chr6_+_24775153 0.25 ENST00000356509.3
ENST00000230056.3
GMNN
geminin, DNA replication inhibitor
chr1_+_6845497 0.24 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr15_+_40987327 0.24 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51
RAD51 recombinase
chr15_+_40987661 0.24 ENST00000526763.1
RAD51
RAD51 recombinase
chr10_+_103911926 0.24 ENST00000605788.1
ENST00000405356.1
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr3_-_44803141 0.24 ENST00000296121.4
KIAA1143
KIAA1143
chr1_-_47779762 0.24 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
STIL
SCL/TAL1 interrupting locus
chr6_-_17706618 0.24 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chrX_+_123095546 0.23 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr20_+_5931497 0.23 ENST00000378886.2
ENST00000265187.4
MCM8
minichromosome maintenance complex component 8
chr3_-_10028366 0.23 ENST00000429759.1
EMC3
ER membrane protein complex subunit 3
chr7_-_6048702 0.23 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr2_-_61108449 0.23 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr6_+_116575329 0.22 ENST00000430252.2
ENST00000540275.1
ENST00000448740.2
DSE
RP3-486I3.7
dermatan sulfate epimerase
RP3-486I3.7
chr8_+_94929077 0.22 ENST00000297598.4
ENST00000520614.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr4_+_55524085 0.22 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr7_-_105516923 0.22 ENST00000478915.1
ATXN7L1
ataxin 7-like 1
chr22_+_35653445 0.22 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMGXB4
HMG box domain containing 4
chr4_+_71859156 0.21 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
DCK
deoxycytidine kinase
chr13_-_26625169 0.21 ENST00000319420.3
SHISA2
shisa family member 2
chr2_+_48010221 0.21 ENST00000234420.5
MSH6
mutS homolog 6
chr2_-_203103185 0.21 ENST00000409205.1
SUMO1
small ubiquitin-like modifier 1
chrX_+_21959108 0.21 ENST00000457085.1
SMS
spermine synthase
chr2_-_232329186 0.20 ENST00000322723.4
NCL
nucleolin
chr20_-_5931109 0.20 ENST00000203001.2
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr13_+_32889605 0.20 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
BRCA2
breast cancer 2, early onset
chr1_-_26233423 0.20 ENST00000357865.2
STMN1
stathmin 1
chr9_-_123639304 0.20 ENST00000436309.1
PHF19
PHD finger protein 19
chr19_+_35521699 0.20 ENST00000415950.3
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr8_+_94929168 0.20 ENST00000518107.1
ENST00000396200.3
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_26232951 0.20 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr17_+_30264014 0.20 ENST00000322652.5
ENST00000580398.1
SUZ12
SUZ12 polycomb repressive complex 2 subunit
chr1_+_222885884 0.20 ENST00000340934.5
BROX
BRO1 domain and CAAX motif containing
chr5_+_138629389 0.20 ENST00000504045.1
ENST00000504311.1
ENST00000502499.1
MATR3
matrin 3
chr15_+_100106244 0.19 ENST00000557942.1
MEF2A
myocyte enhancer factor 2A
chr2_+_174219548 0.19 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
CDCA7
cell division cycle associated 7
chr2_-_17935027 0.19 ENST00000446852.1
SMC6
structural maintenance of chromosomes 6
chr11_-_64739358 0.19 ENST00000301896.5
ENST00000530444.1
C11orf85
chromosome 11 open reading frame 85
chr7_+_116593433 0.19 ENST00000323984.3
ENST00000393449.1
ST7
suppression of tumorigenicity 7
chr8_+_94929273 0.19 ENST00000518573.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_+_238707388 0.19 ENST00000316997.4
RBM44
RNA binding motif protein 44
chr6_+_135502408 0.19 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr5_+_43121607 0.18 ENST00000509156.1
ENST00000508259.1
ENST00000306938.4
ENST00000399534.1
ZNF131
zinc finger protein 131
chr19_+_36705504 0.18 ENST00000456324.1
ZNF146
zinc finger protein 146
chrX_+_53449887 0.18 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chr2_-_17935059 0.18 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
SMC6
structural maintenance of chromosomes 6
chr19_-_36705547 0.18 ENST00000304116.5
ZNF565
zinc finger protein 565
chr19_+_36706024 0.18 ENST00000443387.2
ZNF146
zinc finger protein 146
chr12_-_125399573 0.18 ENST00000339647.5
UBC
ubiquitin C
chr3_-_48229846 0.18 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr7_+_116593536 0.18 ENST00000417919.1
ST7
suppression of tumorigenicity 7
chr1_+_100598691 0.18 ENST00000370143.1
ENST00000370141.2
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr3_-_136471204 0.18 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1
stromal antigen 1
chr11_+_13299186 0.17 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr5_+_43121698 0.17 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
ZNF131
zinc finger protein 131
chr7_+_116593568 0.17 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr13_+_115079949 0.17 ENST00000361283.1
CHAMP1
chromosome alignment maintaining phosphoprotein 1
chr14_+_35452104 0.17 ENST00000216774.6
ENST00000546080.1
SRP54
signal recognition particle 54kDa
chrX_+_46696372 0.17 ENST00000218340.3
RP2
retinitis pigmentosa 2 (X-linked recessive)
chr5_-_122759032 0.17 ENST00000510582.3
ENST00000328236.5
ENST00000306481.6
ENST00000508442.2
ENST00000395431.2
CEP120
centrosomal protein 120kDa
chr11_+_9595180 0.17 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr8_+_128748308 0.17 ENST00000377970.2
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr5_-_79950775 0.17 ENST00000439211.2
DHFR
dihydrofolate reductase
chr6_-_52149475 0.16 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
MCM3
minichromosome maintenance complex component 3
chr12_-_77459306 0.16 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F7
E2F transcription factor 7
chr11_-_59436453 0.16 ENST00000300146.9
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr9_-_99180597 0.16 ENST00000375256.4
ZNF367
zinc finger protein 367
chr20_-_35724388 0.16 ENST00000344359.3
ENST00000373664.3
RBL1
retinoblastoma-like 1 (p107)
chr1_-_222885770 0.16 ENST00000355727.2
ENST00000340020.6
AIDA
axin interactor, dorsalization associated
chr6_-_160210604 0.16 ENST00000420894.2
ENST00000539756.1
ENST00000544255.1
TCP1
t-complex 1
chr3_+_14219858 0.16 ENST00000306024.3
LSM3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr8_-_120868078 0.16 ENST00000313655.4
DSCC1
DNA replication and sister chromatid cohesion 1
chr7_+_90225796 0.16 ENST00000380050.3
CDK14
cyclin-dependent kinase 14
chr15_+_71185148 0.16 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr17_+_42733730 0.15 ENST00000359945.3
ENST00000425535.1
C17orf104
chromosome 17 open reading frame 104
chr7_-_148581251 0.15 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr10_+_96305610 0.15 ENST00000371332.4
ENST00000239026.6
HELLS
helicase, lymphoid-specific
chr14_+_51706886 0.15 ENST00000457354.2
TMX1
thioredoxin-related transmembrane protein 1
chr14_+_36295504 0.15 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr3_+_41240925 0.15 ENST00000396183.3
ENST00000349496.5
ENST00000453024.1
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr2_-_219433014 0.15 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37
ubiquitin specific peptidase 37
chr7_-_559853 0.14 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr17_-_73781567 0.14 ENST00000586607.1
H3F3B
H3 histone, family 3B (H3.3B)
chr7_+_94285637 0.14 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr2_+_48541776 0.14 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr5_+_36876833 0.14 ENST00000282516.8
ENST00000448238.2
NIPBL
Nipped-B homolog (Drosophila)
chr6_-_144329531 0.14 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
PLAGL1
pleiomorphic adenoma gene-like 1
chr7_+_116593292 0.14 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
ST7
suppression of tumorigenicity 7
chr7_+_120591170 0.14 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr7_-_148581360 0.14 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr1_+_222988464 0.14 ENST00000420335.1
RP11-452F19.3
RP11-452F19.3
chr7_+_26240776 0.14 ENST00000337620.4
CBX3
chromobox homolog 3
chr15_+_100106126 0.14 ENST00000558812.1
ENST00000338042.6
MEF2A
myocyte enhancer factor 2A
chr8_-_67525473 0.14 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr20_-_5931051 0.14 ENST00000453074.2
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr2_-_96700664 0.14 ENST00000359548.4
ENST00000377137.3
ENST00000439254.1
ENST00000453542.1
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr4_+_72052964 0.14 ENST00000264485.5
ENST00000425175.1
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chrX_+_118708517 0.14 ENST00000346330.3
UBE2A
ubiquitin-conjugating enzyme E2A
chr13_-_73356009 0.14 ENST00000377780.4
ENST00000377767.4
DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr1_-_23670817 0.13 ENST00000478691.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr10_-_13390021 0.13 ENST00000537130.1
SEPHS1
selenophosphate synthetase 1
chrX_+_118708493 0.13 ENST00000371558.2
UBE2A
ubiquitin-conjugating enzyme E2A
chr17_-_56065540 0.13 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chrX_+_131157322 0.13 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chrX_+_131157290 0.13 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chrX_+_24711997 0.13 ENST00000379068.3
ENST00000379059.3
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit
chr20_+_25388293 0.13 ENST00000262460.4
ENST00000429262.2
GINS1
GINS complex subunit 1 (Psf1 homolog)
chr5_+_138629337 0.13 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
MATR3
matrin 3
chr14_+_35452169 0.13 ENST00000555557.1
SRP54
signal recognition particle 54kDa
chr1_-_243418344 0.13 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr11_-_77705687 0.13 ENST00000529807.1
ENST00000527522.1
ENST00000534064.1
INTS4
integrator complex subunit 4
chr1_-_23670813 0.13 ENST00000374612.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr7_+_120590803 0.13 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chrX_+_70798261 0.13 ENST00000373696.3
ACRC
acidic repeat containing
chr17_+_7477040 0.13 ENST00000581384.1
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr1_-_229694406 0.12 ENST00000344517.4
ABCB10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chrX_-_53449593 0.12 ENST00000375340.6
ENST00000322213.4
SMC1A
structural maintenance of chromosomes 1A
chr14_-_50154921 0.12 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2
polymerase (DNA directed), epsilon 2, accessory subunit
chr6_-_160210715 0.12 ENST00000392168.2
ENST00000321394.7
TCP1
t-complex 1
chr7_+_94139105 0.12 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr4_+_72053017 0.12 ENST00000351898.6
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr2_+_219433588 0.12 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr3_+_44803209 0.12 ENST00000326047.4
KIF15
kinesin family member 15
chr22_+_42394780 0.12 ENST00000328823.9
WBP2NL
WBP2 N-terminal like
chr17_+_58677539 0.12 ENST00000305921.3
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr15_+_80987617 0.12 ENST00000258884.4
ENST00000558464.1
ABHD17C
abhydrolase domain containing 17C
chr5_+_93954358 0.12 ENST00000504099.1
ANKRD32
ankyrin repeat domain 32
chr1_-_243418621 0.12 ENST00000366544.1
ENST00000366543.1
CEP170
centrosomal protein 170kDa
chrX_-_131623982 0.11 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr3_-_133380731 0.11 ENST00000260810.5
TOPBP1
topoisomerase (DNA) II binding protein 1
chr12_-_48499591 0.11 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr12_-_122238464 0.11 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr11_+_74303612 0.11 ENST00000527458.1
ENST00000532497.1
ENST00000530511.1
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr12_-_81331460 0.11 ENST00000549417.1
LIN7A
lin-7 homolog A (C. elegans)
chr4_-_170679024 0.11 ENST00000393381.2
C4orf27
chromosome 4 open reading frame 27
chr12_-_133263893 0.11 ENST00000535270.1
ENST00000320574.5
POLE
polymerase (DNA directed), epsilon, catalytic subunit
chr6_-_27100529 0.11 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr7_-_99699538 0.11 ENST00000343023.6
ENST00000303887.5
MCM7
minichromosome maintenance complex component 7
chr4_-_130014532 0.11 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
SCLT1
sodium channel and clathrin linker 1
chr14_-_69864993 0.10 ENST00000555373.1
ERH
enhancer of rudimentary homolog (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 0.7 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.2 0.6 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.2 1.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.0 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.4 GO:0034059 response to anoxia(GO:0034059)
0.1 0.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.3 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.3 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.2 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.3 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.2 GO:0038162 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.5 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.4 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.5 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:0061010 external genitalia morphogenesis(GO:0035261) gall bladder development(GO:0061010)
0.0 0.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.7 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.1 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.0 GO:0060266 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.4 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.1 GO:0071789 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.2 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.0 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) lung growth(GO:0060437)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.0 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.5 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.5 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.3 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.2 GO:0000811 GINS complex(GO:0000811)
0.1 0.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.7 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.1 GO:1990907 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.5 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.5 GO:0032143 single thymine insertion binding(GO:0032143)
0.1 0.3 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.6 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.6 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 2.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.8 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling