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avrg: A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for ZFHX3

Z-value: 1.29

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Transcription factors associated with ZFHX3

Gene Symbol Gene ID Gene Info
ENSG00000140836.10 ZFHX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZFHX3hg19_v2_chr16_-_73082274_730822740.954.6e-02Click!

Activity profile of ZFHX3 motif

Sorted Z-values of ZFHX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZFHX3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_71934962 1.39 ENST00000543234.1
INPPL1
inositol polyphosphate phosphatase-like 1
chr8_-_145754428 0.76 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr17_+_4692230 0.62 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr17_+_61151306 0.49 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr22_-_30970560 0.45 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr11_+_57559005 0.38 ENST00000534647.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr19_-_58864848 0.36 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr22_-_30722912 0.34 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chrM_-_14670 0.34 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr19_+_50016610 0.33 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_-_111649074 0.29 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr7_+_150725510 0.29 ENST00000461373.1
ENST00000358849.4
ENST00000297504.6
ENST00000542328.1
ENST00000498578.1
ENST00000356058.4
ENST00000477719.1
ENST00000477092.1
ABCB8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr2_-_87248975 0.28 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chr14_+_38033252 0.25 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr7_+_100026406 0.25 ENST00000414441.1
MEPCE
methylphosphate capping enzyme
chr9_-_215744 0.25 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr17_+_17685422 0.22 ENST00000395774.1
RAI1
retinoic acid induced 1
chr19_-_46234119 0.22 ENST00000317683.3
FBXO46
F-box protein 46
chr1_-_168464875 0.22 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr11_-_111649015 0.20 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr2_+_133174147 0.19 ENST00000329321.3
GPR39
G protein-coupled receptor 39
chr19_+_926000 0.19 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chrM_+_10053 0.19 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr2_+_105050794 0.18 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chrM_+_10464 0.18 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr11_-_559377 0.17 ENST00000486629.1
C11orf35
chromosome 11 open reading frame 35
chr16_+_87636474 0.16 ENST00000284262.2
JPH3
junctophilin 3
chrX_-_15288154 0.15 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9
ankyrin repeat and SOCS box containing 9
chr17_-_26697304 0.15 ENST00000536498.1
VTN
vitronectin
chr5_+_60933634 0.14 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr22_-_22337204 0.14 ENST00000430142.1
ENST00000357179.5
TOP3B
topoisomerase (DNA) III beta
chr17_-_26733179 0.14 ENST00000440501.1
ENST00000321666.5
SLC46A1
solute carrier family 46 (folate transporter), member 1
chr7_-_100026280 0.14 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr16_-_75284758 0.14 ENST00000561970.1
BCAR1
breast cancer anti-estrogen resistance 1
chr16_-_69385681 0.13 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr20_-_33735070 0.13 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr11_-_125366089 0.12 ENST00000366139.3
ENST00000278919.3
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr11_-_61687739 0.11 ENST00000531922.1
ENST00000301773.5
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr8_-_101733794 0.11 ENST00000523555.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr1_-_160549235 0.11 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr3_-_49066811 0.10 ENST00000442157.1
ENST00000326739.4
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr4_-_155511887 0.09 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr12_+_53835383 0.09 ENST00000429243.2
PRR13
proline rich 13
chr22_-_30970498 0.09 ENST00000431313.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr13_-_30880979 0.09 ENST00000414289.1
KATNAL1
katanin p60 subunit A-like 1
chr6_-_31681839 0.08 ENST00000409239.1
ENST00000461287.1
LY6G6E
XXbac-BPG32J3.20
lymphocyte antigen 6 complex, locus G6E (pseudogene)
Uncharacterized protein
chr15_+_76352178 0.08 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr6_+_34204642 0.08 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr14_-_54425475 0.07 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr4_-_22444733 0.06 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr17_-_64225508 0.06 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr4_+_74347400 0.06 ENST00000226355.3
AFM
afamin
chr6_-_161085291 0.06 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr2_+_88047606 0.06 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr7_+_133615169 0.06 ENST00000541309.1
EXOC4
exocyst complex component 4
chr5_+_140625147 0.06 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr2_-_60780607 0.05 ENST00000537768.1
ENST00000335712.6
ENST00000356842.4
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr8_+_104831472 0.05 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr7_-_86595190 0.05 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L
KIAA1324-like
chrX_+_9431324 0.05 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr7_-_7575477 0.04 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr7_+_130126012 0.04 ENST00000341441.5
MEST
mesoderm specific transcript
chr13_-_30881134 0.03 ENST00000380617.3
ENST00000441394.1
KATNAL1
katanin p60 subunit A-like 1
chr3_+_69915363 0.03 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr12_+_59989918 0.03 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr8_-_18541603 0.03 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr4_-_69111401 0.03 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr3_-_114477787 0.03 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_+_53835425 0.03 ENST00000549924.1
PRR13
proline rich 13
chr8_+_98900132 0.03 ENST00000520016.1
MATN2
matrilin 2
chr2_+_190541153 0.03 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr4_+_100495864 0.02 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chr5_+_95066823 0.02 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr12_+_53835539 0.02 ENST00000547368.1
ENST00000379786.4
ENST00000551945.1
PRR13
proline rich 13
chr8_-_87242589 0.02 ENST00000419776.2
ENST00000297524.3
SLC7A13
solute carrier family 7 (anionic amino acid transporter), member 13
chr1_-_153585539 0.02 ENST00000368706.4
S100A16
S100 calcium binding protein A16
chr11_+_74459876 0.02 ENST00000299563.4
RNF169
ring finger protein 169
chrX_-_110655306 0.01 ENST00000371993.2
DCX
doublecortin
chr12_+_53835508 0.01 ENST00000551003.1
ENST00000549068.1
ENST00000549740.1
ENST00000546581.1
ENST00000549581.1
ENST00000541275.1
PRR13
PCBP2
proline rich 13
poly(rC) binding protein 2
chr6_-_152793728 0.01 ENST00000495090.2
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_+_170632250 0.01 ENST00000367760.3
PRRX1
paired related homeobox 1
chr14_+_39703112 0.01 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr8_+_104831440 0.00 ENST00000515551.1
RIMS2
regulating synaptic membrane exocytosis 2
chr6_+_28317685 0.00 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
ZKSCAN3
zinc finger with KRAB and SCAN domains 3
chr7_+_48211048 0.00 ENST00000435803.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:0090402 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0072096 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling