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avrg: A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for SPDEF

Z-value: 1.25

Motif logo

Transcription factors associated with SPDEF

Gene Symbol Gene ID Gene Info
ENSG00000124664.6 SPDEF

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPDEFhg19_v2_chr6_-_34524049_34524091-0.991.3e-02Click!

Activity profile of SPDEF motif

Sorted Z-values of SPDEF motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SPDEF

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_57914275 0.60 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DDIT3
DNA-damage-inducible transcript 3
chr8_-_56986768 0.48 ENST00000523936.1
RPS20
ribosomal protein S20
chr12_+_29302023 0.43 ENST00000551451.1
FAR2
fatty acyl CoA reductase 2
chr1_-_43638168 0.42 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr8_-_56987061 0.42 ENST00000009589.3
ENST00000524349.1
ENST00000519606.1
ENST00000519807.1
ENST00000521262.1
ENST00000520627.1
RPS20
ribosomal protein S20
chr11_+_36616355 0.35 ENST00000532470.2
C11orf74
chromosome 11 open reading frame 74
chr4_-_44728530 0.34 ENST00000507534.1
GNPDA2
glucosamine-6-phosphate deaminase 2
chr1_-_43637915 0.33 ENST00000236051.2
EBNA1BP2
EBNA1 binding protein 2
chr1_-_193028426 0.33 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr2_-_63815628 0.32 ENST00000409562.3
WDPCP
WD repeat containing planar cell polarity effector
chr4_+_39640787 0.32 ENST00000532680.1
RP11-539G18.2
RP11-539G18.2
chr19_+_37178482 0.31 ENST00000536254.2
ZNF567
zinc finger protein 567
chr14_+_89029866 0.30 ENST00000557693.1
ENST00000555120.1
ZC3H14
zinc finger CCCH-type containing 14
chr14_+_35761580 0.30 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr1_+_151129135 0.30 ENST00000602841.1
SCNM1
sodium channel modifier 1
chr4_-_44728559 0.30 ENST00000509756.1
ENST00000507917.1
ENST00000295448.3
GNPDA2
glucosamine-6-phosphate deaminase 2
chr3_-_37218023 0.30 ENST00000416425.1
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr1_-_193028632 0.29 ENST00000421683.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr1_+_235492300 0.28 ENST00000476121.1
ENST00000497327.1
GGPS1
geranylgeranyl diphosphate synthase 1
chr1_-_235324772 0.28 ENST00000408888.3
RBM34
RNA binding motif protein 34
chr18_-_19180681 0.28 ENST00000269214.5
ESCO1
establishment of sister chromatid cohesion N-acetyltransferase 1
chr4_+_48833160 0.28 ENST00000506801.1
OCIAD1
OCIA domain containing 1
chr7_+_6414128 0.27 ENST00000348035.4
ENST00000356142.4
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr1_-_235324530 0.27 ENST00000447801.1
ENST00000366606.3
ENST00000429912.1
RBM34
RNA binding motif protein 34
chr14_-_31926623 0.26 ENST00000356180.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr15_+_55700741 0.26 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr17_-_56065540 0.26 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr14_+_35761540 0.26 ENST00000261479.4
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr3_+_197464046 0.26 ENST00000428738.1
FYTTD1
forty-two-three domain containing 1
chr17_+_65714018 0.26 ENST00000581106.1
ENST00000535137.1
NOL11
nucleolar protein 11
chr16_+_25123148 0.25 ENST00000570981.1
LCMT1
leucine carboxyl methyltransferase 1
chr4_+_48833234 0.25 ENST00000510824.1
ENST00000425583.2
OCIAD1
OCIA domain containing 1
chr17_-_56065484 0.25 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr1_-_184723942 0.25 ENST00000318130.8
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chrX_-_131352152 0.25 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr17_+_65713925 0.24 ENST00000253247.4
NOL11
nucleolar protein 11
chr2_+_27805880 0.24 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512
zinc finger protein 512
chr20_+_60962143 0.24 ENST00000343986.4
RPS21
ribosomal protein S21
chr7_+_128379449 0.24 ENST00000479257.1
CALU
calumenin
chr14_+_89029336 0.24 ENST00000556945.1
ENST00000556158.1
ENST00000557607.1
ZC3H14
zinc finger CCCH-type containing 14
chr1_+_67395922 0.24 ENST00000401042.3
ENST00000355356.3
MIER1
mesoderm induction early response 1, transcriptional regulator
chr14_+_60716159 0.24 ENST00000325658.3
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr2_+_198380289 0.24 ENST00000233892.4
ENST00000409916.1
MOB4
MOB family member 4, phocein
chr5_-_114961858 0.23 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2
TMED7
TICAM2
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr6_-_150039249 0.23 ENST00000543571.1
LATS1
large tumor suppressor kinase 1
chr17_-_8286484 0.23 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
RPL26
ribosomal protein L26
chr2_+_162016916 0.23 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr8_-_100025238 0.23 ENST00000521696.1
RP11-410L14.2
RP11-410L14.2
chr2_-_128784846 0.23 ENST00000259235.3
ENST00000357702.5
ENST00000424298.1
SAP130
Sin3A-associated protein, 130kDa
chr5_+_76326187 0.22 ENST00000312916.7
ENST00000506806.1
AGGF1
angiogenic factor with G patch and FHA domains 1
chr2_+_162016827 0.22 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr14_-_69864993 0.22 ENST00000555373.1
ERH
enhancer of rudimentary homolog (Drosophila)
chr12_+_109490370 0.22 ENST00000257548.5
ENST00000536723.1
ENST00000536393.1
USP30
ubiquitin specific peptidase 30
chr14_+_89029366 0.22 ENST00000555799.1
ENST00000555755.1
ENST00000393514.5
ZC3H14
zinc finger CCCH-type containing 14
chr15_-_65809581 0.22 ENST00000341861.5
DPP8
dipeptidyl-peptidase 8
chr2_+_65454863 0.22 ENST00000260641.5
ACTR2
ARP2 actin-related protein 2 homolog (yeast)
chr8_-_130951940 0.22 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
FAM49B
family with sequence similarity 49, member B
chr11_-_32816156 0.21 ENST00000531481.1
ENST00000335185.5
CCDC73
coiled-coil domain containing 73
chr10_-_119806085 0.21 ENST00000355624.3
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr4_-_153700864 0.21 ENST00000304337.2
TIGD4
tigger transposable element derived 4
chr4_+_48833015 0.21 ENST00000509122.1
ENST00000509664.1
ENST00000505922.2
ENST00000514981.1
OCIAD1
OCIA domain containing 1
chr11_+_57480046 0.21 ENST00000378312.4
ENST00000278422.4
TMX2
thioredoxin-related transmembrane protein 2
chr1_-_169337176 0.21 ENST00000472647.1
ENST00000367811.3
NME7
NME/NM23 family member 7
chr1_-_193028621 0.21 ENST00000367455.4
ENST00000367454.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr17_-_7835228 0.21 ENST00000303731.4
ENST00000571947.1
ENST00000540486.1
ENST00000572656.1
TRAPPC1
trafficking protein particle complex 1
chr6_-_150039170 0.20 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr12_+_29302119 0.20 ENST00000536681.3
FAR2
fatty acyl CoA reductase 2
chr1_+_170501270 0.20 ENST00000367763.3
ENST00000367762.1
GORAB
golgin, RAB6-interacting
chr7_-_91875109 0.20 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1
KRIT1, ankyrin repeat containing
chr18_+_48556470 0.20 ENST00000589076.1
ENST00000590061.1
ENST00000591914.1
ENST00000342988.3
SMAD4
SMAD family member 4
chr11_+_94706973 0.20 ENST00000536741.1
KDM4D
lysine (K)-specific demethylase 4D
chr2_-_128785619 0.20 ENST00000450957.1
SAP130
Sin3A-associated protein, 130kDa
chr16_+_25123041 0.19 ENST00000399069.3
ENST00000380966.4
LCMT1
leucine carboxyl methyltransferase 1
chr1_+_235491714 0.19 ENST00000471812.1
ENST00000358966.2
ENST00000282841.5
ENST00000391855.2
GGPS1
geranylgeranyl diphosphate synthase 1
chr14_+_89029253 0.19 ENST00000251038.5
ENST00000359301.3
ENST00000302216.8
ZC3H14
zinc finger CCCH-type containing 14
chr10_-_120840309 0.19 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr11_+_73498898 0.19 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr18_+_21033239 0.19 ENST00000581585.1
ENST00000577501.1
RIOK3
RIO kinase 3
chr2_+_198380763 0.19 ENST00000448447.2
ENST00000409360.1
MOB4
MOB family member 4, phocein
chr7_+_77428149 0.19 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr2_+_39103103 0.19 ENST00000340556.6
ENST00000410014.1
ENST00000409665.1
ENST00000409077.2
ENST00000409131.2
MORN2
MORN repeat containing 2
chrX_+_47444613 0.19 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr1_+_84944926 0.19 ENST00000370656.1
ENST00000370654.5
RPF1
ribosome production factor 1 homolog (S. cerevisiae)
chr4_+_159593418 0.18 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr10_-_14996017 0.18 ENST00000378241.1
ENST00000456122.1
ENST00000418843.1
ENST00000378249.1
ENST00000396817.2
ENST00000378255.1
ENST00000378254.1
ENST00000378278.2
ENST00000357717.2
DCLRE1C
DNA cross-link repair 1C
chr6_-_139308777 0.18 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
REPS1
RALBP1 associated Eps domain containing 1
chr12_+_49961990 0.18 ENST00000551063.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr3_+_32023232 0.18 ENST00000360311.4
ZNF860
zinc finger protein 860
chr2_+_27805971 0.18 ENST00000413371.2
ZNF512
zinc finger protein 512
chr8_-_101964265 0.18 ENST00000395958.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr10_-_15902449 0.18 ENST00000277632.3
FAM188A
family with sequence similarity 188, member A
chr10_-_14996070 0.17 ENST00000378258.1
ENST00000453695.2
ENST00000378246.2
DCLRE1C
DNA cross-link repair 1C
chr4_+_141445311 0.17 ENST00000323570.3
ENST00000511887.2
ELMOD2
ELMO/CED-12 domain containing 2
chr14_+_67826709 0.17 ENST00000256383.4
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr13_+_25670268 0.17 ENST00000281589.3
PABPC3
poly(A) binding protein, cytoplasmic 3
chr4_+_48833119 0.17 ENST00000444354.2
ENST00000509963.1
ENST00000509246.1
OCIAD1
OCIA domain containing 1
chr2_+_48667983 0.17 ENST00000449090.2
PPP1R21
protein phosphatase 1, regulatory subunit 21
chr1_-_184723701 0.17 ENST00000367512.3
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr7_+_139025105 0.17 ENST00000541170.3
C7orf55-LUC7L2
C7orf55-LUC7L2 readthrough
chr4_+_48833312 0.17 ENST00000508293.1
ENST00000513391.2
OCIAD1
OCIA domain containing 1
chr4_-_668108 0.17 ENST00000304312.4
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr3_-_37217756 0.17 ENST00000440230.1
ENST00000421276.2
ENST00000421307.1
ENST00000354379.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr2_+_118846008 0.17 ENST00000245787.4
INSIG2
insulin induced gene 2
chr15_-_59949693 0.17 ENST00000396063.1
ENST00000396064.3
ENST00000484743.1
ENST00000559706.1
ENST00000396060.2
GTF2A2
general transcription factor IIA, 2, 12kDa
chr5_+_31532373 0.16 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22
chromosome 5 open reading frame 22
chr11_+_94706804 0.16 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr22_+_44351419 0.16 ENST00000396202.3
SAMM50
SAMM50 sorting and assembly machinery component
chr12_-_120663792 0.16 ENST00000546532.1
ENST00000548912.1
PXN
paxillin
chr1_+_169337172 0.16 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1
basic leucine zipper nuclear factor 1
chr13_+_111855414 0.16 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr15_-_80215984 0.16 ENST00000485386.1
ENST00000479961.1
ST20
ST20-MTHFS
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr1_+_193028552 0.16 ENST00000400968.2
ENST00000432079.1
TROVE2
TROVE domain family, member 2
chr3_-_196669298 0.15 ENST00000411704.1
ENST00000452404.2
NCBP2
nuclear cap binding protein subunit 2, 20kDa
chr8_-_101734170 0.15 ENST00000522387.1
ENST00000518196.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr1_-_67896069 0.15 ENST00000370995.2
ENST00000361219.6
SERBP1
SERPINE1 mRNA binding protein 1
chr13_+_27998681 0.15 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr14_+_89029323 0.15 ENST00000554602.1
ZC3H14
zinc finger CCCH-type containing 14
chr7_-_38948774 0.15 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr4_-_159592996 0.15 ENST00000508457.1
C4orf46
chromosome 4 open reading frame 46
chrX_+_117629766 0.15 ENST00000276204.6
ENST00000276202.7
DOCK11
dedicator of cytokinesis 11
chr17_-_47755436 0.15 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP
speckle-type POZ protein
chr14_+_60716276 0.15 ENST00000528241.2
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr10_-_14996321 0.15 ENST00000378289.4
DCLRE1C
DNA cross-link repair 1C
chr20_+_42839722 0.15 ENST00000442383.1
ENST00000435163.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr1_-_67896095 0.15 ENST00000370994.4
SERBP1
SERPINE1 mRNA binding protein 1
chr5_+_86564739 0.15 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr4_-_159593179 0.15 ENST00000379205.4
C4orf46
chromosome 4 open reading frame 46
chr2_+_54014168 0.15 ENST00000405123.3
ENST00000185150.4
ENST00000378239.5
ERLEC1
endoplasmic reticulum lectin 1
chr2_+_63816126 0.15 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr5_-_31532160 0.15 ENST00000511367.2
ENST00000513349.1
DROSHA
drosha, ribonuclease type III
chr1_-_19811996 0.15 ENST00000264203.3
ENST00000401084.2
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr2_+_162016804 0.15 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr4_+_48833183 0.15 ENST00000503016.1
OCIAD1
OCIA domain containing 1
chr7_+_77428066 0.15 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr19_-_52674896 0.14 ENST00000322146.8
ENST00000597065.1
ZNF836
zinc finger protein 836
chr21_-_36421626 0.14 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr2_+_101618965 0.14 ENST00000456292.1
ENST00000409711.1
ENST00000441435.1
RPL31
ribosomal protein L31
chr8_-_57906362 0.14 ENST00000262644.4
IMPAD1
inositol monophosphatase domain containing 1
chr15_-_55700216 0.14 ENST00000569205.1
CCPG1
cell cycle progression 1
chr3_-_139108475 0.14 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr2_+_187350973 0.14 ENST00000544130.1
ZC3H15
zinc finger CCCH-type containing 15
chr5_+_158690089 0.14 ENST00000296786.6
UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr19_-_55690758 0.14 ENST00000590851.1
SYT5
synaptotagmin V
chr7_-_91875358 0.14 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1
KRIT1, ankyrin repeat containing
chr3_-_69101461 0.14 ENST00000543976.1
TMF1
TATA element modulatory factor 1
chr20_+_42839600 0.13 ENST00000439943.1
ENST00000437730.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr2_+_187350883 0.13 ENST00000337859.6
ZC3H15
zinc finger CCCH-type containing 15
chr1_+_24829384 0.13 ENST00000374395.4
ENST00000436717.2
RCAN3
RCAN family member 3
chr3_+_100428316 0.13 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TFG
TRK-fused gene
chr14_-_31926701 0.13 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr2_-_27294500 0.13 ENST00000447619.1
ENST00000429985.1
ENST00000456793.1
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr11_-_71823715 0.13 ENST00000545944.1
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr4_+_166128735 0.13 ENST00000226725.6
KLHL2
kelch-like family member 2
chr7_+_114562172 0.13 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr11_-_71823796 0.13 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr2_-_39103014 0.13 ENST00000295373.6
ENST00000417233.1
DHX57
DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
chr4_-_83812157 0.13 ENST00000513323.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr2_-_54014055 0.13 ENST00000263634.3
ENST00000406687.1
GPR75-ASB3
GPR75-ASB3 readthrough
chrX_+_53078273 0.12 ENST00000332582.4
GPR173
G protein-coupled receptor 173
chr16_-_25122735 0.12 ENST00000563176.1
RP11-449H11.1
RP11-449H11.1
chr3_+_100428188 0.12 ENST00000418917.2
ENST00000490574.1
TFG
TRK-fused gene
chr1_+_169337412 0.12 ENST00000426663.1
BLZF1
basic leucine zipper nuclear factor 1
chr3_-_196669248 0.12 ENST00000447325.1
NCBP2
nuclear cap binding protein subunit 2, 20kDa
chr14_+_105212297 0.12 ENST00000556623.1
ENST00000555674.1
ADSSL1
adenylosuccinate synthase like 1
chr3_-_133380731 0.12 ENST00000260810.5
TOPBP1
topoisomerase (DNA) II binding protein 1
chr17_-_47755338 0.12 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
SPOP
speckle-type POZ protein
chr7_+_91875508 0.12 ENST00000265742.3
ANKIB1
ankyrin repeat and IBR domain containing 1
chr11_-_94706705 0.12 ENST00000279839.6
CWC15
CWC15 spliceosome-associated protein homolog (S. cerevisiae)
chr7_+_11013491 0.12 ENST00000403050.3
ENST00000445996.2
PHF14
PHD finger protein 14
chr4_-_83812402 0.12 ENST00000395310.2
SEC31A
SEC31 homolog A (S. cerevisiae)
chr19_+_38880695 0.12 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr12_-_102513843 0.12 ENST00000551744.2
ENST00000552283.1
NUP37
nucleoporin 37kDa
chr12_+_7072354 0.12 ENST00000537269.1
U47924.27
U47924.27
chr7_+_128379346 0.12 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr12_-_64616019 0.12 ENST00000311915.8
ENST00000398055.3
ENST00000544871.1
C12orf66
chromosome 12 open reading frame 66
chr19_-_45004556 0.12 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180
zinc finger protein 180
chr12_+_27396901 0.12 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr2_+_45878790 0.12 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr4_-_83812248 0.12 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
SEC31A
SEC31 homolog A (S. cerevisiae)
chr12_+_118814185 0.11 ENST00000543473.1
SUDS3
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr17_-_62658186 0.11 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr12_+_102513950 0.11 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chr16_+_4666475 0.11 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr12_+_123868320 0.11 ENST00000402868.3
ENST00000330479.4
SETD8
SET domain containing (lysine methyltransferase) 8
chr14_+_60715928 0.11 ENST00000395076.4
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_+_43124087 0.11 ENST00000304979.3
ENST00000372550.1
ENST00000440068.1
PPIH
peptidylprolyl isomerase H (cyclophilin H)
chr21_-_36421535 0.11 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr5_+_93954358 0.11 ENST00000504099.1
ANKRD32
ankyrin repeat domain 32
chr12_+_50794730 0.11 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
LARP4
La ribonucleoprotein domain family, member 4
chr2_+_148602058 0.11 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A
activin A receptor, type IIA
chr17_+_7477040 0.11 ENST00000581384.1
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr12_+_10366223 0.11 ENST00000545290.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr11_+_61197508 0.11 ENST00000541135.1
ENST00000301761.2
RP11-286N22.8
SDHAF2
Uncharacterized protein
succinate dehydrogenase complex assembly factor 2
chr15_-_65810042 0.11 ENST00000321147.6
DPP8
dipeptidyl-peptidase 8
chr11_+_63754294 0.11 ENST00000543988.1
OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr8_+_15397732 0.10 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
TUSC3
tumor suppressor candidate 3
chr3_-_69101413 0.10 ENST00000398559.2
TMF1
TATA element modulatory factor 1
chr1_+_110091189 0.10 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr22_+_44351301 0.10 ENST00000350028.4
SAMM50
SAMM50 sorting and assembly machinery component
chr15_-_65282274 0.10 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0006043 glucosamine catabolic process(GO:0006043)
0.2 0.5 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.4 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.6 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.6 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.3 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.1 0.4 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.4 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.2 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.5 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.4 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.2 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 1.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.3 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.2 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.8 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.2 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.5 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.2 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.3 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.0 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:1903423 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.0 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.0 GO:0090149 mitochondrial membrane fission(GO:0090149)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 0.5 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.4 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.4 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 0.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.4 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.4 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.5 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.2 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.1 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.8 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0035276 ethanol binding(GO:0035276)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo