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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for ZNF8

Z-value: 0.38

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Transcription factors associated with ZNF8

Gene Symbol Gene ID Gene Info
ENSG00000083842.8 zinc finger protein 8
ENSG00000273439.1 zinc finger protein 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF8hg19_v2_chr19_+_58790314_587903580.534.7e-01Click!

Activity profile of ZNF8 motif

Sorted Z-values of ZNF8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_61429315 0.20 ENST00000530725.1
ENST00000532232.1
RP11-163N6.2
chr17_+_48585794 0.19 ENST00000576179.1
ENST00000419930.1
MYCBP associated protein
chr2_+_240323439 0.19 ENST00000428471.1
ENST00000413029.1
Uncharacterized protein
chr19_+_35739897 0.14 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
lipolysis stimulated lipoprotein receptor
chr6_+_29691056 0.14 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
major histocompatibility complex, class I, F
chr10_+_135192695 0.13 ENST00000368539.4
ENST00000278060.5
ENST00000357296.3
polyamine oxidase (exo-N4-amino)
chr19_+_35739782 0.12 ENST00000347609.4
lipolysis stimulated lipoprotein receptor
chr19_-_18392422 0.12 ENST00000252818.3
jun D proto-oncogene
chr22_-_37415475 0.11 ENST00000403892.3
ENST00000249042.3
ENST00000438203.1
thiosulfate sulfurtransferase (rhodanese)
chr9_-_37576333 0.11 ENST00000541607.1
F-box protein 10
chr3_-_9994021 0.10 ENST00000411976.2
ENST00000412055.1
proline-rich transmembrane protein 3
chr5_+_134210035 0.09 ENST00000506916.1
thioredoxin domain containing 15
chr6_+_31939608 0.08 ENST00000375331.2
ENST00000375333.2
serine/threonine kinase 19
chr17_-_56591978 0.08 ENST00000583656.1
myotubularin related protein 4
chrX_+_129535937 0.07 ENST00000305536.6
ENST00000370947.1
RNA binding motif protein, X-linked 2
chr8_+_38244638 0.07 ENST00000526356.1
leucine zipper-EF-hand containing transmembrane protein 2
chr17_+_34136459 0.07 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr5_+_10353780 0.07 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr1_-_246670614 0.07 ENST00000403792.3
SET and MYND domain containing 3
chr1_-_186344802 0.06 ENST00000451586.1
translocated promoter region, nuclear basket protein
chr11_-_46638720 0.06 ENST00000326737.3
harbinger transposase derived 1
chr12_+_52463751 0.06 ENST00000336854.4
ENST00000550604.1
ENST00000553049.1
ENST00000548915.1
chromosome 12 open reading frame 44
chr7_+_117824086 0.06 ENST00000249299.2
ENST00000424702.1
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr17_-_45908875 0.06 ENST00000351111.2
ENST00000414011.1
mitochondrial ribosomal protein L10
chr1_+_70671363 0.05 ENST00000370951.1
ENST00000370950.3
ENST00000405432.1
ENST00000454435.2
serine/arginine-rich splicing factor 11
chr11_+_46402482 0.05 ENST00000441869.1
midkine (neurite growth-promoting factor 2)
chr17_+_48585745 0.05 ENST00000323776.5
MYCBP associated protein
chr4_+_170541678 0.05 ENST00000360642.3
ENST00000512813.1
chloride channel, voltage-sensitive 3
chr2_-_240322643 0.05 ENST00000345617.3
histone deacetylase 4
chr22_+_37415700 0.04 ENST00000397129.1
mercaptopyruvate sulfurtransferase
chr6_-_116601044 0.04 ENST00000368608.3
TSPY-like 1
chr5_-_93447333 0.04 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr11_-_58345569 0.04 ENST00000528954.1
ENST00000528489.1
leupaxin
chr2_+_198365122 0.04 ENST00000604458.1
HSPE1-MOB4 readthrough
chr4_+_170541835 0.03 ENST00000504131.2
chloride channel, voltage-sensitive 3
chr7_-_74489609 0.03 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
Williams-Beuren syndrome chromosome region 16
chr1_-_100715372 0.03 ENST00000370131.3
ENST00000370132.4
dihydrolipoamide branched chain transacylase E2
chr11_-_46638378 0.03 ENST00000529192.1
harbinger transposase derived 1
chr1_+_211500129 0.03 ENST00000427925.2
ENST00000261464.5
TNF receptor-associated factor 5
chr4_+_170541660 0.03 ENST00000513761.1
ENST00000347613.4
chloride channel, voltage-sensitive 3
chr16_+_68573116 0.03 ENST00000570495.1
ENST00000563169.2
ENST00000564323.1
ENST00000562156.1
ENST00000573685.1
ZFP90 zinc finger protein
chr2_-_105946491 0.03 ENST00000393359.2
transforming growth factor, beta receptor associated protein 1
chr22_+_37415676 0.03 ENST00000401419.3
mercaptopyruvate sulfurtransferase
chrX_+_102631248 0.03 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_128913906 0.02 ENST00000356892.3
SAM and SH3 domain containing 3
chr14_+_105941118 0.02 ENST00000550577.1
ENST00000538259.2
cysteine-rich protein 2
chr17_+_7517264 0.02 ENST00000593717.1
ENST00000572182.1
ENST00000574539.1
ENST00000576728.1
ENST00000575314.1
ENST00000570547.1
ENST00000572262.1
ENST00000576478.1
AC007421.1
sex hormone-binding globulin
chr10_-_73611046 0.02 ENST00000394934.1
ENST00000394936.3
prosaposin
chr22_+_37415776 0.02 ENST00000341116.3
ENST00000429360.2
ENST00000404393.1
mercaptopyruvate sulfurtransferase
chr3_+_49236910 0.02 ENST00000452691.2
ENST00000366429.2
coiled-coil domain containing 36
chr22_+_37415728 0.02 ENST00000404802.3
mercaptopyruvate sulfurtransferase
chr12_+_79258547 0.01 ENST00000457153.2
synaptotagmin I
chr8_+_145064233 0.01 ENST00000529301.1
ENST00000395068.4
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr19_+_52074502 0.01 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
zinc finger protein 175
chr17_+_48624450 0.01 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
spermatogenesis associated 20
chr1_-_228296956 0.01 ENST00000366744.1
ENST00000348259.5
ENST00000366747.3
ENST00000366746.3
ENST00000295008.4
ENST00000336520.3
ENST00000366731.5
ENST00000411464.2
ENST00000457264.1
ENST00000336300.5
ENST00000430433.1
ENST00000391867.3
mitochondrial ribosomal protein L55
chr10_-_1034237 0.01 ENST00000381466.1
Uncharacterized protein
chr11_+_46638805 0.01 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
autophagy related 13
chr22_+_30163340 0.01 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr7_+_100303676 0.01 ENST00000303151.4
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr2_+_169926047 0.01 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr6_+_106959718 0.01 ENST00000369066.3
absent in melanoma 1
chr16_+_29973351 0.01 ENST00000602948.1
ENST00000279396.6
ENST00000575829.2
ENST00000561899.2
transmembrane protein 219
chr19_-_55652290 0.00 ENST00000589745.1
troponin T type 1 (skeletal, slow)
chr12_-_46662772 0.00 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
solute carrier family 38, member 1
chr6_+_29691198 0.00 ENST00000440587.2
ENST00000434407.2
major histocompatibility complex, class I, F
chr5_-_137911049 0.00 ENST00000297185.3
heat shock 70kDa protein 9 (mortalin)

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.2 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.1 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway