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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for ZKSCAN1

Z-value: 0.44

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Transcription factors associated with ZKSCAN1

Gene Symbol Gene ID Gene Info
ZKSCAN1
ENSG00000106261.12 zinc finger with KRAB and SCAN domains 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZKSCAN1hg19_v2_chr7_+_99613195_996132060.673.3e-01Click!

Activity profile of ZKSCAN1 motif

Sorted Z-values of ZKSCAN1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_4364762 0.31 ENST00000262366.3
GLIS2
GLIS family zinc finger 2
chr5_+_135394840 0.27 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr22_+_29702572 0.24 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1
growth arrest-specific 2 like 1
chr14_+_101361107 0.21 ENST00000553584.1
ENST00000554852.1
MEG8
maternally expressed 8 (non-protein coding)
chr5_+_174151536 0.20 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr6_-_43276535 0.19 ENST00000372569.3
ENST00000274990.4
CRIP3
cysteine-rich protein 3
chr16_-_838329 0.18 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
RPUSD1
RNA pseudouridylate synthase domain containing 1
chr17_+_36858694 0.17 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr9_+_132934835 0.16 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr19_-_3062465 0.15 ENST00000327141.4
AES
amino-terminal enhancer of split
chr22_+_30805086 0.14 ENST00000439838.1
ENST00000439023.3
RP4-539M6.19
Uncharacterized protein
chr1_+_160321120 0.12 ENST00000424754.1
NCSTN
nicastrin
chr1_+_16083098 0.11 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr1_+_16083123 0.11 ENST00000510393.1
ENST00000430076.1
FBLIM1
filamin binding LIM protein 1
chr20_-_56265680 0.11 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr16_+_616995 0.11 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
PIGQ
NHLRC4
phosphatidylinositol glycan anchor biosynthesis, class Q
NHL repeat containing 4
chrX_+_47441712 0.11 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr1_+_16083154 0.11 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr17_+_18163848 0.11 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
MIEF2
mitochondrial elongation factor 2
chr19_-_3063099 0.10 ENST00000221561.8
AES
amino-terminal enhancer of split
chr1_+_27648648 0.10 ENST00000374076.4
TMEM222
transmembrane protein 222
chr20_+_4152356 0.10 ENST00000379460.2
SMOX
spermine oxidase
chr19_+_8478154 0.10 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr19_-_2739992 0.09 ENST00000545664.1
ENST00000589363.1
ENST00000455372.2
SLC39A3
solute carrier family 39 (zinc transporter), member 3
chr16_+_67562702 0.09 ENST00000379312.3
ENST00000042381.4
ENST00000540839.3
FAM65A
family with sequence similarity 65, member A
chr12_-_123450986 0.09 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr15_+_75494214 0.09 ENST00000394987.4
C15orf39
chromosome 15 open reading frame 39
chr11_+_70049269 0.09 ENST00000301838.4
FADD
Fas (TNFRSF6)-associated via death domain
chr10_-_126432619 0.09 ENST00000337318.3
FAM53B
family with sequence similarity 53, member B
chr16_+_19125252 0.09 ENST00000566735.1
ENST00000381440.3
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr16_+_2076869 0.09 ENST00000424542.2
ENST00000432365.2
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr19_+_13051206 0.09 ENST00000586760.1
CALR
calreticulin
chr1_-_149908217 0.08 ENST00000369140.3
MTMR11
myotubularin related protein 11
chr16_+_50313426 0.08 ENST00000569265.1
ADCY7
adenylate cyclase 7
chr6_+_30844192 0.08 ENST00000502955.1
ENST00000505066.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr11_+_72975524 0.08 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr20_-_62199427 0.08 ENST00000427522.2
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr20_+_43343476 0.08 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr12_+_113416340 0.08 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr16_-_4665023 0.07 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr2_+_74120094 0.07 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2
actin, gamma 2, smooth muscle, enteric
chr10_-_126432821 0.07 ENST00000280780.6
FAM53B
family with sequence similarity 53, member B
chr5_+_149980622 0.07 ENST00000394243.1
SYNPO
synaptopodin
chr5_+_137774706 0.07 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2
receptor accessory protein 2
chr15_-_78112553 0.07 ENST00000562933.1
LINGO1
leucine rich repeat and Ig domain containing 1
chr1_-_155224751 0.07 ENST00000350210.2
ENST00000368368.3
FAM189B
family with sequence similarity 189, member B
chr17_+_17685422 0.07 ENST00000395774.1
RAI1
retinoic acid induced 1
chr2_+_71127699 0.07 ENST00000234392.2
VAX2
ventral anterior homeobox 2
chr4_-_176733897 0.06 ENST00000393658.2
GPM6A
glycoprotein M6A
chr14_+_38033252 0.06 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr1_+_11333245 0.06 ENST00000376810.5
UBIAD1
UbiA prenyltransferase domain containing 1
chr15_+_40731920 0.06 ENST00000561234.1
BAHD1
bromo adjacent homology domain containing 1
chr19_+_10196781 0.06 ENST00000253110.11
C19orf66
chromosome 19 open reading frame 66
chr1_+_46668994 0.06 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chr7_-_72439997 0.06 ENST00000285805.3
TRIM74
tripartite motif containing 74
chr5_+_127039075 0.06 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr11_+_72975559 0.06 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_+_64808675 0.06 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr11_-_61197480 0.06 ENST00000439958.3
ENST00000394888.4
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr2_+_231902193 0.06 ENST00000373640.4
C2orf72
chromosome 2 open reading frame 72
chr17_+_75372165 0.06 ENST00000427674.2
SEPT9
septin 9
chr1_-_160549235 0.05 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr11_-_58343319 0.05 ENST00000395074.2
LPXN
leupaxin
chr19_-_3062881 0.05 ENST00000586742.1
AES
amino-terminal enhancer of split
chr11_+_46366918 0.05 ENST00000528615.1
ENST00000395574.3
DGKZ
diacylglycerol kinase, zeta
chr7_+_73588575 0.05 ENST00000265753.8
EIF4H
eukaryotic translation initiation factor 4H
chr7_+_72742178 0.05 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr10_+_118349920 0.05 ENST00000531984.1
PNLIPRP1
pancreatic lipase-related protein 1
chr4_+_39460620 0.05 ENST00000340169.2
ENST00000261434.3
LIAS
lipoic acid synthetase
chr9_-_123639600 0.05 ENST00000373896.3
PHF19
PHD finger protein 19
chr1_+_27648709 0.05 ENST00000608611.1
ENST00000466759.1
ENST00000464813.1
ENST00000498220.1
TMEM222
transmembrane protein 222
chr17_-_73150629 0.05 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1
hematological and neurological expressed 1
chr12_+_9066472 0.05 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr17_-_73150599 0.04 ENST00000392566.2
ENST00000581874.1
HN1
hematological and neurological expressed 1
chr6_-_30640811 0.04 ENST00000376442.3
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr11_+_72975578 0.04 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr19_-_19051993 0.04 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3
homer homolog 3 (Drosophila)
chr20_+_43343517 0.04 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr3_-_48542197 0.04 ENST00000442747.1
ENST00000444115.1
SHISA5
shisa family member 5
chr2_-_183387430 0.04 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr17_-_15370915 0.04 ENST00000312177.6
CDRT4
CMT1A duplicated region transcript 4
chrX_+_109245863 0.04 ENST00000372072.3
TMEM164
transmembrane protein 164
chr22_-_38484922 0.04 ENST00000428572.1
BAIAP2L2
BAI1-associated protein 2-like 2
chr7_+_73588665 0.04 ENST00000353999.6
EIF4H
eukaryotic translation initiation factor 4H
chr6_-_44281043 0.04 ENST00000244571.4
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr19_+_3178736 0.04 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr19_+_13135790 0.04 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr16_-_19729453 0.04 ENST00000564480.1
KNOP1
lysine-rich nucleolar protein 1
chr6_+_157099036 0.04 ENST00000350026.5
ENST00000346085.5
ENST00000367148.1
ENST00000275248.4
ARID1B
AT rich interactive domain 1B (SWI1-like)
chr15_+_78370140 0.04 ENST00000409568.2
SH2D7
SH2 domain containing 7
chr3_+_53528659 0.04 ENST00000350061.5
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr15_-_78369994 0.04 ENST00000300584.3
ENST00000409931.3
TBC1D2B
TBC1 domain family, member 2B
chr11_+_46366799 0.04 ENST00000532868.2
DGKZ
diacylglycerol kinase, zeta
chr10_+_106113515 0.03 ENST00000369704.3
ENST00000312902.5
CCDC147
coiled-coil domain containing 147
chr1_+_207277632 0.03 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chr17_+_27071002 0.03 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TRAF4
TNF receptor-associated factor 4
chr12_-_49319265 0.03 ENST00000552878.1
ENST00000453172.2
FKBP11
FK506 binding protein 11, 19 kDa
chr2_-_200320768 0.03 ENST00000428695.1
SATB2
SATB homeobox 2
chr9_-_139357413 0.03 ENST00000277537.6
SEC16A
SEC16 homolog A (S. cerevisiae)
chr15_+_75498739 0.03 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr4_+_39460689 0.03 ENST00000381846.1
LIAS
lipoic acid synthetase
chr5_-_134734901 0.03 ENST00000312469.4
ENST00000423969.2
H2AFY
H2A histone family, member Y
chr17_-_39928501 0.03 ENST00000420370.1
JUP
junction plakoglobin
chr13_+_76445187 0.03 ENST00000318245.4
C13orf45
chromosome 13 open reading frame 45
chr4_+_39460659 0.03 ENST00000513731.1
LIAS
lipoic acid synthetase
chr2_+_69201705 0.03 ENST00000377938.2
GKN1
gastrokine 1
chr2_+_27070964 0.03 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr19_+_39138320 0.03 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4
actinin, alpha 4
chr7_+_75024903 0.02 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chr19_+_39647271 0.02 ENST00000599657.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr19_-_344786 0.02 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr17_-_26684473 0.02 ENST00000540200.1
POLDIP2
polymerase (DNA-directed), delta interacting protein 2
chr19_+_16830774 0.02 ENST00000524140.2
NWD1
NACHT and WD repeat domain containing 1
chr1_-_36615065 0.02 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr12_+_8995832 0.02 ENST00000541459.1
A2ML1
alpha-2-macroglobulin-like 1
chr9_-_101558777 0.02 ENST00000375018.1
ENST00000353234.4
ANKS6
ankyrin repeat and sterile alpha motif domain containing 6
chr16_+_56899114 0.02 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
SLC12A3
solute carrier family 12 (sodium/chloride transporter), member 3
chr17_+_5031687 0.02 ENST00000250066.6
ENST00000304328.5
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr1_-_27709793 0.02 ENST00000374027.3
ENST00000374025.3
CD164L2
CD164 sialomucin-like 2
chr2_+_27071045 0.02 ENST00000401478.1
DPYSL5
dihydropyrimidinase-like 5
chrX_-_15402498 0.02 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr12_+_25055243 0.02 ENST00000599478.1
AC026310.1
Protein 101060047
chr2_+_27071292 0.01 ENST00000431402.1
ENST00000434719.1
DPYSL5
dihydropyrimidinase-like 5
chr4_-_186732048 0.01 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr2_-_158345462 0.01 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr16_+_8736232 0.01 ENST00000562973.1
METTL22
methyltransferase like 22
chr7_+_72742162 0.01 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chr1_-_53704157 0.01 ENST00000371466.4
ENST00000371470.3
MAGOH
mago-nashi homolog, proliferation-associated (Drosophila)
chr15_+_78384901 0.01 ENST00000328828.5
SH2D7
SH2 domain containing 7
chr3_-_179322436 0.01 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr10_+_23384435 0.01 ENST00000376510.3
MSRB2
methionine sulfoxide reductase B2
chr9_-_123639445 0.01 ENST00000312189.6
PHF19
PHD finger protein 19
chr11_-_568369 0.01 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG
MIR210 host gene (non-protein coding)
chr12_-_25055177 0.01 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr14_-_67982146 0.01 ENST00000557779.1
ENST00000557006.1
TMEM229B
transmembrane protein 229B
chr3_+_38388251 0.01 ENST00000427323.1
ENST00000207870.3
ENST00000542835.1
XYLB
xylulokinase homolog (H. influenzae)
chr11_-_73720276 0.00 ENST00000348534.4
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr3_+_51663407 0.00 ENST00000432863.1
ENST00000296477.3
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr1_-_51796987 0.00 ENST00000262676.5
TTC39A
tetratricopeptide repeat domain 39A
chr3_-_47023455 0.00 ENST00000446836.1
ENST00000425441.1
CCDC12
coiled-coil domain containing 12
chr6_-_30640761 0.00 ENST00000415603.1
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.3 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.1 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors