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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for ZIC2_GLI1
Z-value: 0.77
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Transcription factors associated with ZIC2_GLI1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GLI1 | hg19_v2_chr12_+_57857475_57857475 | -0.40 | 6.0e-01 | Click! |
| ZIC2 | hg19_v2_chr13_+_100634004_100634026 | -0.38 | 6.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_-_26027480 Show fit | 1.02 |
ENST00000377364.3
|
histone cluster 1, H4b |
|
| chr16_-_21452040 Show fit | 0.45 |
ENST00000521589.1
|
nuclear pore complex interacting protein family, member B3 |
|
| chr20_+_36149602 Show fit | 0.40 |
ENST00000062104.2
ENST00000346199.2 |
neuronatin |
|
| chr1_+_209941942 Show fit | 0.29 |
ENST00000487271.1
ENST00000477431.1 |
TRAF3 interacting protein 3 |
|
| chr16_+_86612112 Show fit | 0.25 |
ENST00000320241.3
|
forkhead box L1 |
|
| chrX_+_47444613 Show fit | 0.25 |
ENST00000445623.1
|
TIMP metallopeptidase inhibitor 1 |
|
| chr15_-_83224682 Show fit | 0.22 |
ENST00000562833.1
|
RP11-152F13.10 |
|
| chr17_+_73089382 Show fit | 0.19 |
ENST00000538213.2
ENST00000584118.1 |
solute carrier family 16 (monocarboxylate transporter), member 5 |
|
| chr20_-_62493217 Show fit | 0.18 |
ENST00000601296.1
|
C20ORF135 |
|
| chr1_-_45308616 Show fit | 0.18 |
ENST00000447098.2
ENST00000372192.3 |
patched 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZIC2_GLI1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.0 | 0.3 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
| 0.0 | 0.3 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.0 | 0.2 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.0 | 0.2 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.0 | 0.2 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
| 0.0 | 0.2 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.0 | 0.1 | GO:1903570 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 0.0 | 0.1 | GO:2000174 | regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176) |
| 0.0 | 0.1 | GO:0034444 | regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.0 | 0.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 0.1 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.0 | 0.1 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
| 0.0 | 0.1 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 0.0 | 0.1 | GO:0005607 | laminin-2 complex(GO:0005607) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0051430 | corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.0 | 0.2 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.0 | 0.2 | GO:0005119 | smoothened binding(GO:0005119) |
| 0.0 | 0.2 | GO:0048185 | activin binding(GO:0048185) |
| 0.0 | 0.1 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
| 0.0 | 0.1 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.0 | 0.1 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.0 | 0.1 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 0.0 | 0.1 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.0 | 0.1 | GO:0035939 | microsatellite binding(GO:0035939) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.2 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |