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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for ZFHX3
Z-value: 0.96
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Transcription factors associated with ZFHX3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZFHX3 | hg19_v2_chr16_-_73082274_73082274 | 0.95 | 4.6e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_+_71934962 Show fit | 1.39 |
ENST00000543234.1
|
inositol polyphosphate phosphatase-like 1 |
|
| chr8_-_145754428 Show fit | 0.76 |
ENST00000527462.1
ENST00000313465.5 ENST00000524821.1 |
chromosome 8 open reading frame 82 |
|
| chr17_+_4692230 Show fit | 0.62 |
ENST00000331264.7
|
glycolipid transfer protein domain containing 2 |
|
| chr17_+_61151306 Show fit | 0.49 |
ENST00000580068.1
ENST00000580466.1 |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
|
| chr22_-_30970560 Show fit | 0.45 |
ENST00000402369.1
ENST00000406361.1 |
galactose-3-O-sulfotransferase 1 |
|
| chr11_+_57559005 Show fit | 0.38 |
ENST00000534647.1
|
catenin (cadherin-associated protein), delta 1 |
|
| chr19_-_58864848 Show fit | 0.36 |
ENST00000263100.3
|
alpha-1-B glycoprotein |
|
| chr22_-_30722912 Show fit | 0.34 |
ENST00000215790.7
|
TBC1 domain family, member 10A |
|
| chrM_-_14670 Show fit | 0.34 |
ENST00000361681.2
|
mitochondrially encoded NADH dehydrogenase 6 |
|
| chr19_+_50016610 Show fit | 0.33 |
ENST00000596975.1
|
Fc fragment of IgG, receptor, transporter, alpha |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZFHX3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 0.5 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 0.3 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 0.0 | 0.2 | GO:0040031 | snRNA modification(GO:0040031) |
| 0.0 | 0.1 | GO:0036511 | trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512) |
| 0.0 | 0.1 | GO:0051958 | methotrexate transport(GO:0051958) |
| 0.0 | 0.1 | GO:0032661 | regulation of interleukin-18 production(GO:0032661) |
| 0.0 | 0.1 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
| 0.0 | 0.1 | GO:0090402 | senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402) |
| 0.0 | 0.1 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 0.3 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.0 | 0.2 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.0 | 0.1 | GO:0071062 | rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.0 | 0.1 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | GO:0034485 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) |
| 0.0 | 0.7 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 0.5 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.1 | 0.3 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.0 | 0.1 | GO:0015350 | methotrexate transporter activity(GO:0015350) |
| 0.0 | 0.1 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.0 | 0.1 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.0 | 0.1 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.0 | 0.1 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |