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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for TP63
Z-value: 0.78
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Transcription factors associated with TP63
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TP63 | hg19_v2_chr3_+_189507432_189507459 | 0.64 | 3.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_+_101417919 Show fit | 0.99 |
ENST00000561338.1
|
aldehyde dehydrogenase 1 family, member A3 |
|
| chr7_-_110174754 Show fit | 0.40 |
ENST00000435466.1
|
AC003088.1 |
|
| chr11_+_393428 Show fit | 0.35 |
ENST00000533249.1
ENST00000527442.1 |
plakophilin 3 |
|
| chr11_+_64073699 Show fit | 0.32 |
ENST00000405666.1
ENST00000468670.1 |
estrogen-related receptor alpha |
|
| chr10_-_75532373 Show fit | 0.31 |
ENST00000595757.1
|
Uncharacterized protein; cDNA FLJ44715 fis, clone BRACE3021430 |
|
| chr20_+_34679725 Show fit | 0.31 |
ENST00000432589.1
|
erythrocyte membrane protein band 4.1-like 1 |
|
| chr19_-_3500635 Show fit | 0.31 |
ENST00000250937.3
|
deoxyhypusine hydroxylase/monooxygenase |
|
| chr17_-_14140166 Show fit | 0.31 |
ENST00000420162.2
ENST00000431716.2 |
CMT1A duplicated region transcript 15 |
|
| chr14_-_94595993 Show fit | 0.30 |
ENST00000238609.3
|
interferon, alpha-inducible protein 27-like 2 |
|
| chr14_+_35514323 Show fit | 0.29 |
ENST00000555211.1
|
family with sequence similarity 177, member A1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TP63
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.0 | GO:0060166 | olfactory pit development(GO:0060166) |
| 0.1 | 0.5 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.1 | 0.4 | GO:0019470 | 4-hydroxyproline catabolic process(GO:0019470) |
| 0.0 | 0.4 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.0 | 0.3 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
| 0.0 | 0.3 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.0 | 0.2 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 0.0 | 0.2 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.0 | 0.2 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.0 | 0.2 | GO:0090131 | mesenchyme migration(GO:0090131) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.3 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 0.2 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.1 | 0.2 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.0 | 0.2 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.0 | 0.1 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 0.0 | 0.1 | GO:0031523 | Myb complex(GO:0031523) |
| 0.0 | 0.1 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.0 | 0.1 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) |
| 0.0 | 0.1 | GO:1990393 | 3M complex(GO:1990393) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.1 | 0.5 | GO:0004974 | leukotriene B4 receptor activity(GO:0001632) leukotriene receptor activity(GO:0004974) |
| 0.1 | 0.4 | GO:0003842 | 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842) |
| 0.0 | 0.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 0.2 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.0 | 0.2 | GO:0034040 | lipid-transporting ATPase activity(GO:0034040) |
| 0.0 | 0.2 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 0.2 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.0 | 0.1 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.0 | 0.1 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |